STIP1 (NM_006819) Human Untagged Clone

CAT#: SC115872

STIP1 (untagged)-Human stress-induced-phosphoprotein 1 (STIP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STIP1
• Synonyms: HEL-S-94n; HOP; IEF-SSP-3521; P60; STI1; STI1L
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115872 sequence for NM_006819 edited (data generated by NextGen Sequencing)
  ATGGAGCAGGTCAATGAGCTGAAGGAGAAAGGCAACAAGGCCCTGAGCGTGGGTAACATC
  GATGATGCCTTACAGTGCTACTCCGAAGCTATTAAGCTGGATCCCCACAACCACGTGCTG
  TACAGCAACCGTTCTGCTGCCTATGCCAAGAAAGGAGACTACCAGAAGGCTTATGAGGAT
  GGCTGCAAGACTGTCGACCTAAAGCCTGACTGGGGCAAGGGCTATTCACGAAAAGCAGCA
  GCTCTAGAGTTCTTAAACCGCTTTGAAGAAGCCAAGCGAACCTATGAGGAGGGCTTAAAA
  CACGAGGCAAATAACCCTCAACTGAAAGAGGGTTTACAGAATATGGAGGCCAGGTTGGCA
  GAGAGAAAATTCATGAACCCTTTCAACATGCCTAATCTGTATCAGAAGTTGGAGAGTGAT
  CCCAGGACAAGGACACTACTCAGTGATCCTACCTACCGGGAGCTGATAGAGCAGCTACGA
  AACAAGCCTTCTGACCTGGGCACGAAACTACAAGATCCCCGGATCATGACCACTCTCAGC
  GTCCTCCTTGGGGTCGATCTGGGCAGTATGGATGAGGAGGAAGAGATTGCAACACCTCCA
  CCACCACCCCCTCCCAAAAAGGAGACCAAGCCAGAGCCAATGGAAGAAGATCTTCCAGAG
  AATAAGAAGCAGGCACTGAAAGAAAAAGAGCTGGGGAACGATGCCTACAAGAAGAAAGAC
  TTTGACACAGCCTTGAAGCATTACGACAAAGCCAAGGAGCTGGACCCCACTAACATGACT
  TACATTACCAATCAAGCAGCGGTATACTTTGAAAAGGGCGACTACAATAAGTGCCGGGAG
  CTTTGTGAGAAGGCCATTGAAGTGGGGAGAGAAAACCGAGAAGACTATCGACAGATTGCC
  AAAGCATATGCTCGAATTGGCAACTCCTACTTCAAAGAAGAAAAGTACAAGGATGCCATC
  CATTTCTATAACAAGTCTCTGGCAGAGCACCGAACCCCAGATGTGCTCAAGAAATGCCAG
  CAGGCAGAGAAAATCCTGAAGGAGCAAGAGCGGCTGGCCTACATAAACCCCGACCTGGCT
  TTGGAGGAGAAGAACAAAGGCAACGAGTGTTTTCAGAAAGGGGACTATCCCCAGGCCATG
  AAGCATTATACAGAAGCCATCAAAAGGAACCCGAAAGATGCCAAATTATACAGCAATCGA
  GCTGCCTGCTACACCAAACTCCTGGAGTTCCAGCTGGCACTCAAGGACTGTGAGGAATGT
  ATCCAGCTGGAGCCGACCTTCATCAAGGGTTATACACGGAAAGCCGCTGCGCTGGAAGCG
  ATGAAGGACTACACCAAAGCCATGGATGTGTACCAGAAGGCGCTAGACCTGGACTCCAGC
  TGTAAGGAGGCGGCAGACGGCTACCAGCGCTGTATGATGGCGCAGTACAACCGGCACGAC
  AGCCCCGAAGATGTGAAGCGACGAGCCATGGCCGACCCTGAGGTGCAGCAGATCATGAGT
  GACCCAGCCATGCGCCTTATCCTGGAACAGATGCAGAAGGACCCCCAGGCACTCAGCGAA
  CACTTAAAGAATCCTGTAATAGCACAGAAGATCCAGAAGCTGATGGATGTGGGTCTGATT
  GCAATTCGGTGA
  
  Clone variation with respect to NM_006819.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006819 unedited
  GTTANCATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGCGGCGCGTG
  CGGTTGGGAACGCGGAGCGGACGGATTCGATTCAACGGGGTTCCGGACCGCGCTGCGCTA
  TGGAGCAGGTCAATGAGCTGAAGGAGAAAGGCAACAAGGCCCTGAGCGTGGGTAACATCG
  ATGATGCCTTACAGTGCTACTCCGAAGCTATTAAGCTGGATCCCCACAACCACGTGCTGT
  ACAGCAACCGTTCTGCTGCCTATGCCAAGAAAGGAGACTACCAGAAGGCTTATGAGGATG
  GCTGCAAGACTGTCGACCTAAAGCCTGACTGGGGCAAGGGCTATTCACGAAAAGCAGCAG
  CTCTAGAGTTCTTAAACCGCTTTGAAGAAGCCAAGCGAACCTATGAGGAGGGCTTAAAAC
  ACGAGGCAAATAACCCTCAACTGAAAGAGGGTTTACAGAATATGGAGGCCAGGTTGGCAG
  AGAGAAAATTCATGAACCCTTTCAACATGCCTAATCTGTATCAGAAGTTGGAGAGTGATC
  CCAGGACAAGGACACTACTCAGTGATCCTACCTACCGGGAGCTGATAGAGCAGCTACGAA
  ACAAGCCTTCTGACCTGNGCACGAAACTACAAGATCCCCGGATCATGACCACTCTCAGCG
  TCCTCCTTGGGGTCGATCTGGGCAGTATGGATGAGGAGGAAGAGATTGCAACACCTNCAC
  CACCNACCCCTCCCAAAAAGGAGACCAAGCCAGAGCCAATGGAAGAAGATCTTCCAGAGA
  ATAAGAAGCAGGCACTGAAAGACAAAGACTGGGGAACGATGCCCTACAGAAAGAAGACCT
  TGACACAGCCTTGAAGCATTACGACAAAGCCAAGGAGCTGGACCCCNACTACATGACTTA
  CATTACCAATCAGCAGCGGTATACTTTGAN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006819 unedited
  AGCTATGNCCGCGGCCGCAATCTAGNAGTCGGTTTTTTTTTTTTTTTTTTAACCACGCCC
  CAACTGGGGCTTGTTTTATTGGGAGAAAGGGGGACCGCAGAATAAACAACGTGAGACAGC
  TGGGACCTGAGGCTGGAAGAACCCCCTCCCCTCCCCATAACATGCCCACTGCCCCAAATA
  AAAAAAAAACCAACTATGGGAGAGCAGCCGAGACAGCAACTAGGGGCAGGGGAAAGAGAC
  ATGGAACTCGAGGGCAGCGGTGAAGAGACCATGCGTGTGCTGGGAGGGCCCAGAGGCAGC
  GGCGGCACAAACAGCGCAGGTACGAGTCTCTGTGTCTTCCCCGGGGTTATGTATAAATAT
  AGAGAGATGAGGCCTTCTCTCCCCTGCTCTCCCTTCCGCTCCGTGCTGCTCGCCGCGGTC
  CCAGCTCCTCTTTCCACATGAGGGCGAAGGGAAGGGGGGATGAACAAGTCATCACCGAAT
  TGCAATCAGACCCACATCCATCAGCTTCTGGATCTTCTGTGCTATTACAGGATTCTTTAA
  GTGTTCGCTGAGTGCCTGGGGGTCCTTCTGCATCTGTTCCAGGATAAGGCGCATGGCTGG
  GTCACTCATGATCTGCTGCACCTCAGGGTCGGCCATGGCTCGTCGCTTCACATCTTCGGG
  GCTGTCGTGCCGGTTGTACTGCGCCATCATACAGCGCTGGTAGCCGTCTGCCGCCTCCTT
  ACAGCTGGAGTCCAGGTCTAGCGCCTTCTGGTACACATCCATGGCTTTGGTGTAGTCCTT
  CATCGCTTCCAGCGCAGCGGCTTTCCGTGTATACCCTTGATGAAGGGTCGCTCAGCTGGA
  ACATNNCTCACATCCTTTGATGCAGCTGGAACTCCAGAGTTGGTGTACAGGCGCTCGAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006819
• ORF Size: 1632 bp
• Insert Size: 2440
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006819.1, NP_006810.1
• RefSeq Size: 2113
• RefSeq ORF: 1632
• Locus ID: 10963
• Domains: TPR, STI1
• Protein Families: Stem cell - Pluripotency
• Protein Pathways: Prion diseases
• Gene Summary: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]). [supplied by OMIM, Jul 2009]
  Transcript Variant: This variant (2) uses an alternate 5' terminal exon and thus differs in the 5' UTR and 5' coding region, and uses an alternate start codon, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform a.