Complement Component 6 (C6) (NM_000065) Human Untagged Clone

CAT#: SC115886

C6 (untagged)-Human complement component 6 (C6), transcript variant 1


  "NM_000065" in other vectors (4)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol C6
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC115886 sequence for NM_000065 edited (data generated by NextGen Sequencing)
ATGGCCAGACGCTCTGTCTTGTACTTCATCCTGCTGAATGCTCTGATCAACAAGGGCCAA
GCCTGCTTCTGTGATCACTATGCATGGACTCAGTGGACCAGCTGCTCAAAAACTTGCAAT
TCTGGAACCCAGAGCAGACACAGACAAATAGTAGTAGATAAGTACTACCAGGAAAACTTT
TGTGAACAGATTTGCAGCAAGCAGGAGACTAGAGAATGTAACTGGCAAAGATGCCCCATC
AACTGCCTCCTGGGAGATTTTGGACCATGGTCAGACTGTGACCCTTGTATTGAAAAACAG
TCTAAAGTTAGATCTGTCTTGCGTCCCAGTCAGTTTGGGGGACAGCCATGCACTGAGCCT
CTGGTAGCCTTTCAACCATGCATTCCATCTAAGCTCTGCAAAATTGAAGAGGCTGACTGC
AAGAATAAATTTCGCTGTGACAGTGGCCGCTGCATTGCCAGAAAGTTAGAATGCAATGGA
GAAAATGACTGTGGAGACAATTCAGATGAAAGGGACTGTGGGAGGACAAAGGCAGTATGC
ACACGGAAGTATAATCCCATCCCTAGTGTACAGTTGATGGGCAATGGGTTTCATTTTCTG
GCAGGAGAGCCCAGAGGAGAAGTCCTTGATAACTCTTTCACTGGAGGAATATGTAAAACT
GTCAAAAGCAGTAGGACAAGTAATCCATACCGTGTTCCGGCCAATCTGGAAAATGTCGGC
TTTGAGGTACAAACTGCAGAAGATGACTTGAAAACAGATTTCTACAAGGATTTAACTTCT
CTTGGACACAATGAAAATCAACAAGGCTCATTCTCAAGTCAGGGGGGGAGCTCTTTCAGT
GTACCAATTTTTTATTCCTCAAAGAGAAGTGAAAATATCAACCATAATTCTGCCTTCAAA
CAAGCCATTCAAGCCTCTCACAAAAAGGATTCTAGTTTTATTAGGATCCATAAAGTGATG
AAAGTCTTAAACTTCACAACGAAAGCTAAAGATCTGCACCTTTCTGATGTCTTTTTGAAA
GCACTTAACCATCTGCCTCTAGAATACAACTCTGCTTTGTACAGCCGAATATTCGATGAC
TTTGGGACTCATTACTTCACCTCTGGCTCCCTGGGAGGCGTGTATGACCTTCTCTATCAG
TTTAGCAGTGAGGAACTAAAGAACTCAGGTTTAACCGAGGAAGAAGCCAAACACTGTGTC
AGGATTGAAACAAAGAAACGCGTTTTATTTGCTAAGAAAACAAAAGTGGAACATAGGTGC
ACCACCAACAAGCTGTCAGAGAAACATGAAGGTTCATTTATACAGGGAGCAGAGAAATCC
ATATCCCTGATTCGAGGTGGAAGGAGTGAATATGGAGCAGCTTTGGCATGGGAGAAAGGG
AGCTCTGGTCTGGAGGAGAAGACATTTTCTGAGTGGTTAGAATCAGTGAAGGAAAATCCT
GCTGTGATTGACTTTGAGCTTGCCCCCATCGTGGACTTGGTAAGAAACATCCCCTGTGCA
GTGACAAAACGGAACAACCTCAGGAAAGCTTTGCAAGAGTATGCAGCCAAGTTCGATCCT
TGCCAGTGTGCTCCATGCCCTAATAATGGCCGACCCACCCTCTCAGGGACTGAATGTCTG
TGTGTGTGTCAGAGTGGCACCTATGGTGAGAACTGTGAGAAACAGTCTCCAGATTATAAA
TCCAATGCAGTAGACGGACAGTGGGGTTGTTGGTCTTCCTGGAGTACCTGTGATGCTACT
TATAAGAGATCGAGAACCCGAGAATGCAATAATCCTGCCCCCCAACGAGGAGGGAAACGC
TGTGAGGGGGAGAAGCGACAAGAGGAAGACTGCACATTTTCAATCATGGAAAACAATGGA
CAACCATGTATCAATGATGATGAAGAAATGAAAGAGGTCGATCTTCCTGAGATAGAAGCA
GATTCCGGGTGTCCTCAGCCAGTTCCTCCAGAAAATGGATTTATCCGGAATGAAAAGCAA
CTATACTTGGTTGGAGAAGATGTTGAAATTTCATGCCTTACTGGCTTTGAAACTGTTGGA
TACCAGTACTTCAGATGCTTACCAGACGGGACCTGGAGACAAGGGGATGTGGAATGCCAA
CGGACGGAGTGCATCAAGCCAGTTGTGCAGGAAGTCCTGACAATTACACCATTTCAGAGA
TTGTATAGAATTGGTGAATCCATTGAGCTAACTTGCCCCAAAGGCTTTGTTGTTGCTGGG
CCATCAAGGTACACATGCCAGGGGAATTCCTGGACACCACCCATTTCAAACTCTCTCACC
TGTGAAAAAGATACTCTAACAAAATTAAAAGGCCATTGTCAGCTGGGACAGAAACAATCA
GGATCTGAATGCATTTGTATGTCTCCAGAAGAAGACTGTAGCCATCATTCAGAAGATCTC
TGTGTGTTTGACACAGACTCCAACGATTACTTTACTTCACCCGCTTGTAAGTTTTTGGCT
GAGAAATGTTTAAATAATCAGCAACTCCATTTTCTACATATTGGTTCCTGCCAAGACGGC
CGCCAGTTAGAATGGGGTCTTGAAAGGACAAGACTTTCATCCAACAGCACAAAGAAAGAA
TCCTGTGGCTATGACACCTGCTATGACTGGGAAAAATGTTCAGCCTCCACTTCCAAATGT
GTCTGCCTATTGCCCCCACAGTGCTTCAAGGGTGGAAACCAACTCTACTGTGTCAAAATG
GGATCATCAACAAGTGAGAAAACATTGAACATCTGTGAAGTGGGAACTATAAGATGTGCA
AACAGGAAGATGGAAATACTGCATCCTGGAAAGTGTTTGGCCTAG

Clone variation with respect to NM_000065.2
356 c=>a
>OriGene 5' read for NM_000065 unedited
CTAGATTTTGTATCCGACTTACTATNAGGNCGGCACGCGCAATTCGGCACGAGGCATTGC
CTTGTGTTAGCTAGCAATAAGAAAAGAAGCTTTGTTTGGATTAACATATATACCCTCTTC
ATTCTGCATACCTATTTTTTCCCCAATAATTTGCAGCTTATGTCCGAGGACACCACAAAC
TCTGCTTAAAGGGCCTGGAGGCTCTCAAGGCATGGCCAGACGCTCTGTCTTGTACTTCAT
CCTGCTGAATGCTCTGATCAACAAGGGCCAAGCCTGCTTCTGTGATCACTATGCATGGAC
TCAGTGGACCAGCTGCTCAAAAACTTGCAATTCTGGAACCCAGAGCAGACACAGACAAAT
AGTAGTAGATAAGTACTACCAGGAAAACTTTTGTGAACAGATTTGCAGCAAGCAGGAGAC
TAGAGAATGTAACTGGCAAAGATGCCCCATCAACTGCCTCCTGGGAGATTTTGGACCATG
GTCAGACTGTGACCCTTGTATTGAAAAACAGTCTAAAGTTAGATCTGTCTTGCGTCCCAG
TCAGTTTGGGGGACAGCCATGCACTGAGCCTCTGGTAGCCTTTCAACCATGCATTCCATC
TAAGCTCTGCAAAATTGAAGAGGCTGACTGCAAGAATAAATTTCGCTGTGACAGTGGCCG
CTGCATTGCCAGATAGTTAGAATGCAATGGAGAAAATGACTGTGGAGACCATTCAGATGA
TAGGGACTGTGGGAGGACATAGGCAGTATGCACACGGAAGTATAATCCCATCCCTAGTGT
ACAGTTGATGGGCAATGGNGTTCATTTTCTGGCAAGAGAGCCCAGAAGAGAAGTCCTTGA
TACTCTTNCCTGGNAGAATATGTAAACTGTCAAAGCAGTAGGACAAGTAATCATACCGTG
TNCCGCCATCTGNAAATGTCGCTTNGAGTACAACTGCAGAGAGACTGAA
>OriGene 3' read for NM_000065 unedited
TTCTATGNACCGCGCCGCATTCTAGGATCGAGTTTTTTTTTTTTTTTTTTTCAGAGTTCT
GGAGATTTCTGTTTATTAACTCATTGAAAAAAATATGGGTTTTATTCTTATTTCTAATTG
TGAGAATGCTTAATGTCACAGGCTACATAAGGGCCTCAAAAGTCACATTATTTTTGTACA
ATGTGAACAGGAGAATTTACGAGACTGCTGTGGAAGTTGGTACCTAGGGGTATGCTACAG
GGCGTCATGAGCTGGAACTGAATAAGACATGCCCAAACAGGAGAGTCAGGGGAGAATAAT
GATCTCAAACTAACAGAAAATAATTTTTGTCAGTAACTTTGAGCATGCCAGTCTGCTGTT
TGTGCAAGAATTCTCATTTGTAGGAGTTGGTTCTTCGGGATGGTAAATCTGTTCATTGTG
CTGGGCCTAGCAGTAATTGTGCTAGGCCAAACACTTTCCAGGATGCAGTATTTCCATCTT
CCTGTTTGCACATCTTATAGTTCCCACTTCACAGATGTTCAATGTTTTCTCACTTGTTGA
TGATCCCATTTTGACACAGTAGAGTTGGTTTCCACCCTTGAAGCACTGTGGGGGCAATAG
GCAGACACATTTGGAAGTGGAGGCTGAACATTNTTCCCAGTCATAGCAGGTGTCATAGCC
ACAGGATTCTTTCTTTGTGCTGTTGGATGAAAGTCTTGTCCTTTCAGACCCCATTCTAAC
TGGNCGCCGTCTTGGCAGGAACCCATATGTAGAANATGGGAGTGCTGATTATTTAAACAT
TNCTCACCAAAAACTTTACAGCGGGTGAAGTAAAGTATCGTTGGAGTCTGTGTCAAACCA
CAGAGATCTTCTGATGATGGCTACAGTCTTCTTCTGGAGAATACAAAGCATTCGATCCTG
ANTGTTCTGTCCAGCTGACATGGCCTTTTAANTTGTAGATATCTTTTACAGTGAAAA
Restriction Sites NotI-NotI     
ACCN NM_000065
Insert Size 3110 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_000065.1, NP_000056.1
RefSeq Size 3551 bp
RefSeq ORF 2805 bp
Locus ID 729
Cytogenetics 5p13.1
Domains CCP, tsp_1, MACPF, ldl_recept_a, kazal, FIMAC
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus
Gene Summary 'This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012]'
Transcript Variant: This variant (1) represents the predominant transcript. Variants 1 and 2 both encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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