PDE10A (NM_006661) Human Untagged Clone

CAT#: SC115943

PDE10A (untagged)-Human phosphodiesterase 10A (PDE10A), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PDE10A
• Synonyms: ADSD2; HSPDE10A; IOLOD; LINC00473; PDE10A19
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001130690 edited
  ACTCCGCGGCGTCCCCAGGGCGCCAGCTTCGCCCTCGCCGCCGCGGCCGCGCTGCTCTTC
  GGCTCCGACATGGAAGATGGACCTTCTAATAATGCGAGCTGCTTCCGAAGGCTGACCGAG
  TGCTTCCTGAGCCCCAGTTTGACAGATGAAAAAGTGAAGGCATATCTTTCTCTTCACCCC
  CAGGTATTAGATGAATTTGTATCTGAAAGTGTTAGTGCAGAGACAGTAGAGAAATGGCTG
  AAGAGGAAGAACAACAAATCAGAAGATGAATCAGCTCCTAAGGAAGTCAGCAGGTACCAA
  GATACGAATATGCAGGGAGTTGTATATGAACTAAACAGCTATATAGAACAACGGTTGGAC
  ACAGGAGGAGACAACCAGCTACTCCTCTATGAACTGAGCAGCATCATTAAAATAGCCACA
  AAAGCCGATGGATTTGCACTGTATTTCCTTGGAGAGTGCAATAATAGCCTGTGTATATTC
  ACGCCACCTGGGATAAAGGAAGGAAAACCCCGCCTCATCCCTGCTGGGCCCATCACTCAG
  GGCACCACCGTCTCTGCTTATGTGGCCAAGTCCAGGAAAACACTGCTAGTAGAAGACATC
  CTTGGAGATGAACGATTTCCAAGAGGTACTGGACTGGAATCAGGGACTCGTATCCAGTCT
  GTTCTTTGCTTACCAATTGTCACTGCAATTGGTGACTTGATTGGTATTCTCGAGCTGTAT
  CGGCACTGGGGCAAAGAAGCCTTCTGTCTTAGTCACCAGGAGGTTGCAACAGCAAATCTT
  GCCTGGGCTTCAGTAGCAATACATCAGGTGCAGGTATGCAGAGGCCTTGCCAAACAGACA
  GAATTGAATGACTTCCTACTCGACGTATCAAAAACATATTTTGATAACATAGTTGCAATA
  GATTCTCTACTTGAACACATAATGATATATGCAAAAAACCTGGTGAATGCCGATCGTTGT
  GCGCTTTTCCAGGTGGACCATAAGAACAAGGAGTTATATTCAGACCTTTTTGATATTGGA
  GAGGAAAAGGAAGGAAAACCTGTCTTCAAGAAGACCAAAGAGATAAGATTTTCAATTGAG
  AAAGGAATTGCTGGCCAAGTAGCAAGAACAGGGGAAGTCCTGAACATTCCAGATGCCTAT
  GCAGACCCACGCTTTAACAGAGAAGTAGACTTGTACACAGGCTACACCACGCGGAACATC
  CTGTGCATGCCCATCGTCAGCCGAGGCAGCGTGATAGGTGTGGTGCAGATGGTCAACAAA
  ATCAGTGGCAGTGCCTTCTCTAAAACAGATGAAAACAACTTCAAAATGTTTGCCGTCTTT
  TGTGCTTTAGCCTTACACTGTGCTAATATGTATCATAGAATTCGCCACTCAGAGTGCATT
  TACCGGGTAACGATGGAAAAGCTGTCCTACCATAGCATTTGTACTTCAGAAGAGTGGCAA
  GGTCTCATGCAATTCACCCTTCCCGTGCGTCTCTGCAAAGAAATTGAATTATTCCACTTT
  GACATTGGTCCTTTTGAAAACATGTGGCCTGGAATTTTTGTCTACATGGTTCATCGGTCC
  TGTGGGACATCCTGCTTTGAGCTTGAAAAGTTGTGTCGTTTTATTATGTCTGTGAAGAAG
  AACTATCGGCGGGTTCCTTATCACAACTGGAAGCATGCGGTCACTGTAGCACACTGCATG
  TATGCCATACTTCAGAACAATCACACGCTTTTCACAGACCTTGAGCGCAAAGGACTGCTG
  ATTGCGTGTCTGTGTCATGACCTGGACCACAGGGGCTTCAGTAACAGCTACCTGCAGAAG
  TTCGACCACCCTCTGGCCGCTCTCTACTCCACTTCCACCATGGAGCAGCACCACTTCTCC
  CAGACTGTGTCCATCCTCCAGTTGGAAGGGCACAATATCTTCTCCACTCTGAGCTCCAGT
  GAATATGAGCAGGTGCTTGAGATCATCCGCAAAGCCATCATTGCCACAGACCTTGCTTTA
  TACTTTGGAAACAGGAAGCAGTTGGAAGAGATGTACCAGACCGGATCACTAAACCTTAAT
  AATCAATCACATAGAGACCGTGTAATTGGTTTGATGATGACTGCCTGTGACCTTTGTTCT
  GTGACAAAACTGTGGCCCGTTACAAAATTGACGGCAAATGATATATATGCAGAATTCTGG
  GCTGAGGGTGATGAAATGAAGAAATTGGGAATACAGCCTATTCCTATGATGGACAGAGAC
  AAGAAGGATGAAGTCCCCCAAGGCCAGCTTGGGTTCTACAATGCCGTGGCCATTCCCTGC
  TATACAACCCTTACCCAGATCCTCCCTCCCACGGAGCCTCTTCTGAAAGCATGCAGGGAT
  AATCTCAGTCAGTGGGAGAAGGTGATTCGAGGGGAGGAGACTGCAACCTGGATTTCATCC
  CCATCCGTGGCTCAGAAGGCAGCTGCATCTGAAGATTGAGCACTGGTCACCCTGACACGC
  TGTCCCACCTACAGATCCTCATCTTGCTTCTTTGACATTCTTTTCCTTTTTTTGGGGGGG
  GTGGGGGGAACCTGCACCT
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006661 unedited
  NGGGGTTCACATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCAGCTC
  CCTTGAGCGTCCCCACCAGCAGTAGTCACCGCGGCGGCGGTGGCAGCGGCGGCGGGCGGC
  GGCGGCTCTTCCTCTCGCCTGCGCTCCAGGGCTTGCTGCTTCCAGCCCGTGCCGGTCCCC
  GGCCGCCGCCGCCGCCCCGGCTCCCCCTTGGCCAGGCCGCCCGCCGCGCGGGCTCCCCCG
  GCTTCCCCGGCGCCGGCCCAGGCGGCGGCGGCCAAACTCCGCGGCGTCCCCAGGGCGCCA
  GCTTCGCCCTCGCCGCCGCGGCCGCGCTGCTCTTCGGCTCCGACATGGAAGATGGACCTT
  CTAATAATGCGAGCTGCTTCCGAAGGCTGACCGAGTGCTTCCTGAGCCCCAGTTTGACAG
  ATGAAAAAGTGAAGGCATATCTTTCTCTTCACCCCCAGGTATTAGATGAATTTGTATCTG
  AAAGTGTTAGTGCAGAGACAGTAGAGAAATGGCTGAAGAGGAAGAACAACAAATCAGAAG
  ATGAATCAGCTCCTAAGGAAGTCAGCAGGTACCAAGATACGAATATGCAGGGAGTTGTAT
  ATGAACTAAACAGCTATATAGAACAACGGTTGGACACAGGAGGAGACAACCAGCTACTCC
  TCTATGAACTGAGCAGCATCATTAAAATAGCCACAAAAGCCGATGGATTTGCACTGTATT
  TCCTTGGAGAGTGCAATAATAGCCTGTGTATATTCACGCCACCTGNGATAAAGGAAGGAA
  AACCCCGNCTCATCCCTGCTGGGCCCATCACTCAGGGCACCACCGTCTCTGCTTATGTGG
  CCAAGTCCAGGAAACACTGCTAGTAGAAGACTCCTTGGAGATGACGATTNCCAAGAGTAC
  TGGACTGGATCAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006661 unedited
  TAATGGACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTATTTTGTTCT
  TTATGCAAAGGGTTCAGTAAAACTGCCAANACAACAACAAAAACAATTTTAAAAACTGAC
  ATCTTTTGAACTGCTACTTGAAGTTCTGAGATTTATTGTAACATATACCTCATCTCTTCT
  CAAAAAGACAGGAAGTCTACTTCGTCTAGTGTTAAATTTATTGATCTCAGCCCTTTAGGT
  TGAACTTAAAGAATTATGTTTAGTCTAACTAAATTCATGAAGCTCTGAAATAAGAGTTTG
  ACGTTTTGCCATCATTTCTTACTCTGTAACCTCAACGACATTTGTCCTGAGGCTGTGGAC
  TACAACTCAAGTTAATTACAAGTAGGTCATACATGAACATTCACCATTCACAATAGTAAT
  GTGTAAAAATTCCTATTTATATCCAACAACATCAAAGCAACATTGATGTTAAAGCCCAAG
  TACAATACCATAATAGTACCATTTTAAACCCTTATTAGAAAGATACAATGGAAAAGTACC
  CCTTCTGGATAATTTTTGTCCATTTCCTTTAAGGCCTCAGCAATATTAGCCTATTAGAAA
  AGGCTGGTTTGCAAGTCAAATGGAGTCACTTGGCCAGCTGATTTCTGAACGTGGGGGTGG
  TCCTGGTTGCTCAGTGTCTATGATGCCTCACAGAAGAGATTGGCAGGAAGTCCTCTGCTT
  GACTTATTTATTTGATGGTACCTTCTTGAAGAGGTTTGCACCCCAGTTACCAGGTGCANG
  TTCCCCCCACCCCCCCCAAAAAAAGGAAAAAATGNTCAAAAGCCAGATGAGGATCTCGTA
  GTGGGACAGCGTGTCAAGGTGACCAGTGCTCAATCTTCAGATGCAGCTGCCCTCTGAGCC
  CCGNATGGGGATGAAAATCCAGTTGCAGGCTCCTCCCTCCAAAAACCTTTTCCCCCTGAC
  TGAGATATTACCTGCATGCGTTCAAAAGAGGCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006661
• ORF Size: 2340 bp
• Insert Size: 2600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006661.1, NP_006652.1
• RefSeq Size: 4576
• RefSeq ORF: 2340
• Locus ID: 10846
• Domains: PDEase, GAF
• Protein Families: Druggable Genome
• Protein Pathways: Progesterone-mediated oocyte maturation, Purine metabolism
• Gene Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011]
  Transcript Variant: This variant (2) has an additional exon in the 5' region, which includes an in-frame AUG start codon, as compared to variant 1. The resulting isoform (2) has an alternate and shorter N-terminus, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.