PDE10A (NM_006661) Human Untagged Clone

CAT#: SC115943

PDE10A (untagged)-Human phosphodiesterase 10A (PDE10A), transcript variant 2


  "NM_006661" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PDE10A
Synonyms ADSD2; HSPDE10A; IOLOD; LINC00473; PDE10A19
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_001130690 edited
ACTCCGCGGCGTCCCCAGGGCGCCAGCTTCGCCCTCGCCGCCGCGGCCGCGCTGCTCTTC
GGCTCCGACATGGAAGATGGACCTTCTAATAATGCGAGCTGCTTCCGAAGGCTGACCGAG
TGCTTCCTGAGCCCCAGTTTGACAGATGAAAAAGTGAAGGCATATCTTTCTCTTCACCCC
CAGGTATTAGATGAATTTGTATCTGAAAGTGTTAGTGCAGAGACAGTAGAGAAATGGCTG
AAGAGGAAGAACAACAAATCAGAAGATGAATCAGCTCCTAAGGAAGTCAGCAGGTACCAA
GATACGAATATGCAGGGAGTTGTATATGAACTAAACAGCTATATAGAACAACGGTTGGAC
ACAGGAGGAGACAACCAGCTACTCCTCTATGAACTGAGCAGCATCATTAAAATAGCCACA
AAAGCCGATGGATTTGCACTGTATTTCCTTGGAGAGTGCAATAATAGCCTGTGTATATTC
ACGCCACCTGGGATAAAGGAAGGAAAACCCCGCCTCATCCCTGCTGGGCCCATCACTCAG
GGCACCACCGTCTCTGCTTATGTGGCCAAGTCCAGGAAAACACTGCTAGTAGAAGACATC
CTTGGAGATGAACGATTTCCAAGAGGTACTGGACTGGAATCAGGGACTCGTATCCAGTCT
GTTCTTTGCTTACCAATTGTCACTGCAATTGGTGACTTGATTGGTATTCTCGAGCTGTAT
CGGCACTGGGGCAAAGAAGCCTTCTGTCTTAGTCACCAGGAGGTTGCAACAGCAAATCTT
GCCTGGGCTTCAGTAGCAATACATCAGGTGCAGGTATGCAGAGGCCTTGCCAAACAGACA
GAATTGAATGACTTCCTACTCGACGTATCAAAAACATATTTTGATAACATAGTTGCAATA
GATTCTCTACTTGAACACATAATGATATATGCAAAAAACCTGGTGAATGCCGATCGTTGT
GCGCTTTTCCAGGTGGACCATAAGAACAAGGAGTTATATTCAGACCTTTTTGATATTGGA
GAGGAAAAGGAAGGAAAACCTGTCTTCAAGAAGACCAAAGAGATAAGATTTTCAATTGAG
AAAGGAATTGCTGGCCAAGTAGCAAGAACAGGGGAAGTCCTGAACATTCCAGATGCCTAT
GCAGACCCACGCTTTAACAGAGAAGTAGACTTGTACACAGGCTACACCACGCGGAACATC
CTGTGCATGCCCATCGTCAGCCGAGGCAGCGTGATAGGTGTGGTGCAGATGGTCAACAAA
ATCAGTGGCAGTGCCTTCTCTAAAACAGATGAAAACAACTTCAAAATGTTTGCCGTCTTT
TGTGCTTTAGCCTTACACTGTGCTAATATGTATCATAGAATTCGCCACTCAGAGTGCATT
TACCGGGTAACGATGGAAAAGCTGTCCTACCATAGCATTTGTACTTCAGAAGAGTGGCAA
GGTCTCATGCAATTCACCCTTCCCGTGCGTCTCTGCAAAGAAATTGAATTATTCCACTTT
GACATTGGTCCTTTTGAAAACATGTGGCCTGGAATTTTTGTCTACATGGTTCATCGGTCC
TGTGGGACATCCTGCTTTGAGCTTGAAAAGTTGTGTCGTTTTATTATGTCTGTGAAGAAG
AACTATCGGCGGGTTCCTTATCACAACTGGAAGCATGCGGTCACTGTAGCACACTGCATG
TATGCCATACTTCAGAACAATCACACGCTTTTCACAGACCTTGAGCGCAAAGGACTGCTG
ATTGCGTGTCTGTGTCATGACCTGGACCACAGGGGCTTCAGTAACAGCTACCTGCAGAAG
TTCGACCACCCTCTGGCCGCTCTCTACTCCACTTCCACCATGGAGCAGCACCACTTCTCC
CAGACTGTGTCCATCCTCCAGTTGGAAGGGCACAATATCTTCTCCACTCTGAGCTCCAGT
GAATATGAGCAGGTGCTTGAGATCATCCGCAAAGCCATCATTGCCACAGACCTTGCTTTA
TACTTTGGAAACAGGAAGCAGTTGGAAGAGATGTACCAGACCGGATCACTAAACCTTAAT
AATCAATCACATAGAGACCGTGTAATTGGTTTGATGATGACTGCCTGTGACCTTTGTTCT
GTGACAAAACTGTGGCCCGTTACAAAATTGACGGCAAATGATATATATGCAGAATTCTGG
GCTGAGGGTGATGAAATGAAGAAATTGGGAATACAGCCTATTCCTATGATGGACAGAGAC
AAGAAGGATGAAGTCCCCCAAGGCCAGCTTGGGTTCTACAATGCCGTGGCCATTCCCTGC
TATACAACCCTTACCCAGATCCTCCCTCCCACGGAGCCTCTTCTGAAAGCATGCAGGGAT
AATCTCAGTCAGTGGGAGAAGGTGATTCGAGGGGAGGAGACTGCAACCTGGATTTCATCC
CCATCCGTGGCTCAGAAGGCAGCTGCATCTGAAGATTGAGCACTGGTCACCCTGACACGC
TGTCCCACCTACAGATCCTCATCTTGCTTCTTTGACATTCTTTTCCTTTTTTTGGGGGGG
GTGGGGGGAACCTGCACCT
>OriGene 5' read for NM_006661 unedited
NGGGGTTCACATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCAGCTC
CCTTGAGCGTCCCCACCAGCAGTAGTCACCGCGGCGGCGGTGGCAGCGGCGGCGGGCGGC
GGCGGCTCTTCCTCTCGCCTGCGCTCCAGGGCTTGCTGCTTCCAGCCCGTGCCGGTCCCC
GGCCGCCGCCGCCGCCCCGGCTCCCCCTTGGCCAGGCCGCCCGCCGCGCGGGCTCCCCCG
GCTTCCCCGGCGCCGGCCCAGGCGGCGGCGGCCAAACTCCGCGGCGTCCCCAGGGCGCCA
GCTTCGCCCTCGCCGCCGCGGCCGCGCTGCTCTTCGGCTCCGACATGGAAGATGGACCTT
CTAATAATGCGAGCTGCTTCCGAAGGCTGACCGAGTGCTTCCTGAGCCCCAGTTTGACAG
ATGAAAAAGTGAAGGCATATCTTTCTCTTCACCCCCAGGTATTAGATGAATTTGTATCTG
AAAGTGTTAGTGCAGAGACAGTAGAGAAATGGCTGAAGAGGAAGAACAACAAATCAGAAG
ATGAATCAGCTCCTAAGGAAGTCAGCAGGTACCAAGATACGAATATGCAGGGAGTTGTAT
ATGAACTAAACAGCTATATAGAACAACGGTTGGACACAGGAGGAGACAACCAGCTACTCC
TCTATGAACTGAGCAGCATCATTAAAATAGCCACAAAAGCCGATGGATTTGCACTGTATT
TCCTTGGAGAGTGCAATAATAGCCTGTGTATATTCACGCCACCTGNGATAAAGGAAGGAA
AACCCCGNCTCATCCCTGCTGGGCCCATCACTCAGGGCACCACCGTCTCTGCTTATGTGG
CCAAGTCCAGGAAACACTGCTAGTAGAAGACTCCTTGGAGATGACGATTNCCAAGAGTAC
TGGACTGGATCAC
>OriGene 3' read for NM_006661 unedited
TAATGGACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTATTTTGTTCT
TTATGCAAAGGGTTCAGTAAAACTGCCAANACAACAACAAAAACAATTTTAAAAACTGAC
ATCTTTTGAACTGCTACTTGAAGTTCTGAGATTTATTGTAACATATACCTCATCTCTTCT
CAAAAAGACAGGAAGTCTACTTCGTCTAGTGTTAAATTTATTGATCTCAGCCCTTTAGGT
TGAACTTAAAGAATTATGTTTAGTCTAACTAAATTCATGAAGCTCTGAAATAAGAGTTTG
ACGTTTTGCCATCATTTCTTACTCTGTAACCTCAACGACATTTGTCCTGAGGCTGTGGAC
TACAACTCAAGTTAATTACAAGTAGGTCATACATGAACATTCACCATTCACAATAGTAAT
GTGTAAAAATTCCTATTTATATCCAACAACATCAAAGCAACATTGATGTTAAAGCCCAAG
TACAATACCATAATAGTACCATTTTAAACCCTTATTAGAAAGATACAATGGAAAAGTACC
CCTTCTGGATAATTTTTGTCCATTTCCTTTAAGGCCTCAGCAATATTAGCCTATTAGAAA
AGGCTGGTTTGCAAGTCAAATGGAGTCACTTGGCCAGCTGATTTCTGAACGTGGGGGTGG
TCCTGGTTGCTCAGTGTCTATGATGCCTCACAGAAGAGATTGGCAGGAAGTCCTCTGCTT
GACTTATTTATTTGATGGTACCTTCTTGAAGAGGTTTGCACCCCAGTTACCAGGTGCANG
TTCCCCCCACCCCCCCCAAAAAAAGGAAAAAATGNTCAAAAGCCAGATGAGGATCTCGTA
GTGGGACAGCGTGTCAAGGTGACCAGTGCTCAATCTTCAGATGCAGCTGCCCTCTGAGCC
CCGNATGGGGATGAAAATCCAGTTGCAGGCTCCTCCCTCCAAAAACCTTTTCCCCCTGAC
TGAGATATTACCTGCATGCGTTCAAAAGAGGCCC
Restriction Sites NotI-NotI     
ACCN NM_006661
ORF Size 2340 bp
Insert Size 2600
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_006661.1, NP_006652.1
RefSeq Size 4576
RefSeq ORF 2340
Locus ID 10846
Domains PDEase, GAF
Protein Families Druggable Genome
Protein Pathways Progesterone-mediated oocyte maturation, Purine metabolism
Gene Summary The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011]
Transcript Variant: This variant (2) has an additional exon in the 5' region, which includes an in-frame AUG start codon, as compared to variant 1. The resulting isoform (2) has an alternate and shorter N-terminus, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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