ATG7 (NM_006395) Human Untagged Clone

CAT#: SC116085

ATG7 (untagged)-Human ATG7 autophagy related 7 homolog (S. cerevisiae) (ATG7), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ATG7
• Synonyms: APG7-LIKE; APG7L; GSA7
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006395 edited
  GAATTCGGCACGAGGGCCGGAAGTTGAGCGGCGGCAAGAAATAATGGCGGCAGCTACGGG
  GGATCCTGGACTCTCTAAACTGCAGTTTGCCCCTTTTAGTAGTGCCTTGGATGTTGGGTT
  TTGGCATGAGTTGACCCAGAAGAAGCTGAACGAGTATCGGCTGGATGAAGCTCCCAAGGA
  CATTAAGGGTTATTACTACAATGGTGACTCTGCTGGGCTGCCAGCTCGCTTAACATTGGA
  GTTCAGTGCTTTTGACATGAGTGCTCCCACCCCAGCCCGTTGCTGCCCAGCTATTGGAAC
  ACTGTATAACACCAACACACTCGAGTCTTTCAAGACTGCAGATAAGAAGCTCCTTTTGGA
  ACAAGCAGCAAATGAGATATGGGAATCCATAAAATCAGGCACTGCTCTTGAAAACCCTGT
  ACTCCTCAACAAGTTCCTCCTCTTGACATTTGCAGATCTAAAGAAGTACCACTTCTACTA
  TTGGTTTTGCTATCCTGCCCTCTGTCTTCCAGAGAGTTTACCTCTCATTCAGGGGCCAGT
  GGGTTTGGATCAAAGGTTTTCACTAAAACAGATTGAAGCACTAGAGTGTGCATATGATAA
  TCTTTGTCAAACAGAAGGAGTCACAGCTCTTCCTTACTTCTTAATCAAGTATGATGAGAA
  CATGGTGCTGGTTTCCTTGCTTAAACACTACAGTGATTTCTTCCAAGGTCAAAGGACGAA
  GATAACAATTGGTGTATATGATCCCTGTAACTTAGCCCAGTACCCTGGATGGCCTTTGAG
  GAATTTTTTGGTCCTAGCAGCCCACAGATGGAGTAGCAGTTTCCAGTCTGTTGAAGTTGT
  TTGCTTCCGTGACCGTACCATGCAGGGGGCGAGAGACGTTGCCCACAGCATCATCTTCGA
  AGTGAAGCTTCCAGAAATGGCATTTAGCCCAGATTGTCCTAAAGCAGTTGGATGGGAAAA
  GAACCAGAAAGGAGGCATGGGACCAAGGATGGTGAACCTCAGTGAATGTATGGACCCTAA
  AAGGTTAGCTGAGTCATCAGTGGATCTAAATCTCAAACTGATGTGTTGGAGATTGGTTCC
  TACTTTAGACTTGGACAAGGTTGTGTCTGTCAAATGTCTGCTGCTTGGAGCCGGCACCTT
  GGGTTGCAATGTAGCTAGGACGTTGATGGGTTGGGGCGTGAGACACATCACATTTGTGGA
  CAATGCCAAGATCTCCTACTCCAATCCTGTGAGGCAGCCTCTCTATGAGTTTGAAGATTG
  CCTAGGGGGTGGTAAGCCCAAGGCTCTGGCAGCAGCGGACCGGCTCCAGAAAATATTCCC
  CGGTGTGAATGCCAGAGGATTCAACATGAGCATACCTATGCCTGGGCATCCAGTGAACTT
  CTCCAGTGTCACTCTGGAGCAAGCCCGCAGAGATGTGGAGCAACTGGAGCAGCTCATCGA
  AAGCCATGATGTCGTCTTCCTATTGATGGACACCAGGGAGAGCCGGTGGCTTCCTGCCGT
  CATTGCTGCAAGCAAGAGAAAGCTGGTCATCAATGCTGCTTTGGGATTTGACACATTTGT
  TGTCATGAGACATGGTCTGAAGAAACCAAAGCAGCAAGGAGCTGGGGACTTGTGTCCAAA
  CCACCCTGTGGCATCTGCTGACCTCCTGGGCTCATCGCTTTTTGCCAACATCCCTGGTTA
  CAAGCTTGGCTGCTACTTCTGCAATGATGTGGTGGCCCCAGGAGATTCAACCAGAGACCG
  GACCTTGGACCAGCAGTGCACTGTGAGTCGTCCAGGACTGGCCGTGATTGCAGGAGCCCT
  GGCCGTGGAATTGATGGTATCTGTTTTGCAGCATCCAGAAGGGGGCTATGCCATTGCCAG
  CAGCAGTGACGATCGGATGAATGAGCCTCCAACCTCTCTTGGGCTTGTGCCTCACCAGAT
  CCGGGGATTTCTTTCACGGTTTGATAATGTCCTTCCCGTCAGCCTGGCATTTGACAAATG
  TACAGCTTGTTCTTCCAAAGTTCTTGATCAATATGAACGAGAAGGATTTAACTTCCTAGC
  CAAGGTGTTTAATTCTTCACATTCCTTCTTAGAAGACTTGACTGGTCTTACATTGCTGCA
  TCAAGAAACCCAAGCTGCTGAGATCTGGGACATGAGCGACGATGAGACCATCTGAGATGG
  CCCCGCTGTGGGGCTGACTTCTCCCCGGCCGCCTGCTGAGGAGCTCTCCATCGCCAGAGC
  AGGACTGCTGACCCCAGGCTTGGTGATTCTGGGCCCCTCCTCCATACCCCGAGGTCTGGG
  ATTCCCCCCTCTGCTGCCCAGGAGTGGCCAGTGTTCGGCGTTGCTCGGGATTCAAGATAC
  CACCAGTTCAGAGCTAAATAATAACCTTGGCCTTGGCCTTGCTATTGACCTGGGAAAAAA
  AAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006395 unedited
  TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCGGAAGTTGAGCGG
  CGGCAAGAAATAATGGCGGCAGCTACGGGGGATCCTGGACTCTCTAAACTGCAGTTTGCC
  CCTTTTAGTAGTGCCTTGGATGTTGGGTTTTGGCATGAGTTGACCCAGAAGAAGCTGAAC
  GAGTATCGGCTGGATGAAGCTCCCAAGGACATTAAGGGTTATTACTACAATGGTGACTCT
  GCTGGGCTGCCAGCTCGCTTAACATTGGAGTTCAGTGCTTTTGACATGAGTGCTCCCACC
  CCAGCCCGTTGCTGCCCAGCTATTGGAACACTGTATAACACCAACACACTCGAGTCTTTC
  AAGACTGCAGATAAGAAGCTCCTTTTGGAACAAGCAGCAAATGAGATATGGGAATCCATA
  AAATCAGGCACTGCTCTTGAAAACCCTGTACTCCTCAACAAGTTCCTCCTCTTGACATTT
  GCAGATCTAAAGAAGTACCACTTCTACTATTGGTTTTGCTATCCTGCCCTCTGTCTTCCA
  GAGAGTTTACCTCTCATTCAGGGGCCAGTGGGTTTGGATCAAAGGTTTTCACTAAAACAG
  ATTGAAGCACTAGAGTGTGCATATGATAATCTTTGTCAAACAGAAGGAGTCACAGCTCTT
  CCTTACTTCTTAATCAAGTATGATGAGAACATGGTGCTGGTTTCCTTGCTTAACACTACA
  GTGATTTCTTTCAGGTCAAAGGACGAAGATAACATTGGTGTATATGATCCCCNTGTACTA
  CCCAGTACCCTGGATGGCCTTTGAGGGATNTTTAGTCCTAGCAGCCACAGATGGAGTANN
  CAGTTCCAGTCTGGTGAAAGTGTTTGCTTCCGTGACCGTACATGCAGGGGGCGANAGAAC
  GTGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006395 unedited
  ATGGACCGCGGCCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCCCAGTCAATAG
  CAAGGCCAAGGCCAAGGTTATTATTTAGCTCTGAACTGGTGGCATCTTGAATCCCGAGCA
  ACGCCGAACACTGGCCACTCCTGGGCAGCAGAGGGGGGAATCCCAGACCTCGGGGTATGG
  AGGAGGGGCCCAGAATCACCAAGCCTGGGGTCAGCAGTCCTGCTCTGGCGATGGAGAGCT
  CCTCAGCACGCGGCCGGGGAGAAGTCAGCCCCACAGCGGGGCCATCTCAGATGGTCTCAT
  CGCCGCTCATGTCCCAGATCTCAGCAGCTTGGGTTTCTTGATGCAGCAATGTAAGACCAG
  TCAAGTCTTCTAAGAAGGAATGTGAAGAATTAAACCCCTTGGCTAGGAAGTTAACTCCTT
  CTCGCTCATATCGATCAACAACTTTGGAAGAACAAGCTGTACATTTGTCAAATTGCCAGG
  CTGACGGGAAGGACATCTTCAAACCGTGAAAGAAATCCCCGGTTCTGGCGAGGCACAACC
  CCCAAAAAGGTTGGAGGCTCTTTATTCCCGATCGCACTTGTGCTTGGCAATGGCTTAACC
  CCCTTTATGGATGCTGCAAAACACATACCCATTCATTCCACCGCGCCGGGCTCCTGCATC
  CACCGCGCATCCAGGAAAACCCACACCGCCACTGTGGGTCCAAGGTCCGCGCCTCGGACA
  AATCTTCTGGGCCCCCCCCTTTTTCACATATCTATACCCCTCCTTCGTACCCCTGGCCCC
  CGACACAAACCCAGTGCTCCACCAGCGCCACCCAACCCCCACGCGGCCCCGGACACAGTC
  CCCCCGCCCCCCGTGTGCTCGTTCCCTTNTCCCATCCCCCACCACCCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006395
• ORF Size: 2112 bp
• Insert Size: 2380
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006395.1, NP_006386.1
• RefSeq Size: 2396
• RefSeq ORF: 2112
• Locus ID: 10533
• Domains: ThiF
• Protein Pathways: Regulation of autophagy
• Gene Summary: This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
  Transcript Variant: This variant (1), as well as variants 4, 5, 6, and 7, encodes the longest isoform (a).