NPC2 (NM_006432) Human Untagged Clone

CAT#: SC116115

NPC2 (untagged)-Human Niemann-Pick disease, type C2 (NPC2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NPC2
• Synonyms: EDDM1; HE1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116115 sequence for NM_006432 edited (data generated by NextGen Sequencing)
  ATGCGTTTCCTGGCAGCTACATTCCTGCTCCTGGCGCTCAGCACCGCTGCCCAGGCCGAA
  CCGGTGCAGTTCAAGGACTGCGGTTCTGTGGATGGAGTTATAAAGGAAGTGAATGTGAGC
  CCATGCCCCACCCAACCCTGCCAGCTGAGCAAAGGACAGTCTTACAGCGTCAATGTCACC
  TTCACCAGCAATATTCAGTCTAAAAGCAGCAAGGCCGTGGTGCATGGCATCCTGATGGGC
  GTCCCAGTTCCCTTTCCCATTCCTGAGCCTGATGGTTGTAAGAGTGGAATTAACTGCCCT
  ATCCAAAAAGACAAGACCTATAGCTACCTGAATAAACTACCAGTGAAAAGCGAATATCCC
  TCTATAAAACTGGTGGTGGAGTGGCAACTTCAGGATGACAAAAACCAAAGTCTCTTCTGC
  TGGGAAATCCCAGTACAGATCGTTTCTCATCTCTAA
  
  Clone variation with respect to NM_006432.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006432 unedited
  ATATTTGTATACGACTCACTATAGGGCGGCNCGCGAATTCGCACGAGGCCTGACTGGGCT
  CCTCCCCGGGCCCGCCCCGACGGTTTGTCTTGTGACCGCGGGCGGCCGCTGCTTCTTTCC
  CGAGCTTGGAACTTCGTTATCCGCGATGCGTTTCCTGGCAGCTACATTCCTGCTCCTGGC
  GCTCAGCACCGCTGCCCAGGCCGAACCGGTGCAGTTCAAGGACTGCGGTTCTGTGGATGG
  AGTTATAAAGGAAGTGAATGTGAGCCCATGCCCCACCCAACCCTGCCAGCTGAGCAAAGG
  ACAGTCTTACAGCGTCAATGTCACCTTCACCAGCAATATTCAGTCTAAAAGCAGCAAGGC
  CGTGGTGCATGGCATCCTGATGGGCGTCCCAGTTCCCTTTCCCATTCCTGAGCCTGATGG
  TTGTAAGAGTGGAATTAACTGCCCTATCCAAAAAGACAAGACCTATAGCTACCTGAATAA
  ACTACCAGTGAAAAGCGAATATCCCTCTATAAAACTGGTGGTGGAGTGGCAACTTCAGGA
  TGACAAAAACCAAAGTCTCTTCTGCTGGGAAATCCCAGTACAGATCGTTTCTCATCTCTA
  AGTGCCTCATTGAGTTCGGTGCATCTGGCCAATGAGTCTGCTGAGACTCTTGACAGCACC
  TCCAGCTCTGCTGCTTCAACAACAGTGACTTGCTCTCCAATGGTATCCCAGTGATTCGTT
  GAAGAGGAGGTGCTCTGTAGCAGAAACTGAGCTCCGGGTGGCTGGTTCTCAGTGGTTGNC
  TCATGTCTCTTTTTCTGTCTTAAGNGGNTTCATTAATGCAGCACTTGGNTAGCAGATGTT
  TATTTTTTTTTTAACACATAAACTTGTGGCCTCTTCTACACCTGGAATTTACTCTGAATA
  ATAAAACTCGTTGTCCTGTCTCTGCAAAAAAAAAAAAAACTCGCTCTAGATGCGGCCGCG
  TCAAGCTGTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006432 unedited
  GCGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTGCAGAAGACAGACAAACGAG
  TTTTTATTTATTCAAGAGTAAATTTCCAGGTGTAGAAAGAGGCCACAAGTTAATGTTGTT
  AAAAAAAAAATTAAACATCTGCTAACCAAGTGCTGCATTTAATGAAACCACCTAAGACAG
  AAAAAGAGACATGAGACAACCACTGAGAACCAGCCACCCGGAGCTCAGTTTCTGCTACAG
  AGCACCTCCTCTTCAACGAATCACTGGATACCATTGGAGAGCAAGTCACTGTTGTTGAAG
  CAGCAGAGCTGGAGGTGCTGTCAAGAGTCTCAGCAGACTCATTGGCCAGATGCACCGAAC
  TCAATGAGGCACTTAGAGATGAGAAACGATCTGTACTGGGATTTCCCAGCAGAAGAGACT
  TTGGTTTTTGTCATCCTGAAGTTGCCACTCCACCACCAGTTTTATAGAGGGATATTCGCT
  TTTCACTGGTAGTTTATTCAGGTAGCTATAGGTCTTGTCTTTTTGGATAGGGCAGTTAAT
  TCCACTCTTACAACCATCAGGCTCAGGAATGGGAAAGGGAACTGGGACGCCCATCAGGAT
  GCCATGCACCACGGCCTTGCTGCTTTTAGACTGAATATTGCTGGTGAAGGTGACATTGAC
  GCTGTAAGACTGTCCTTTGCTCANCTGGCANGGGTTGGGTGGGGCATGGGCTCACATTCA
  CTTCCTTTATACTNCATCCACAGACCGCAGTCCTTTGACTGCACCCGGTTCGCCTGGGNN
  CACGTGCTGNACGCCAGGACAGGAATGTANCTGCAGGAAACGCATCGCGGATAACGAAAG
  TCCCAGCTCGGGAAAGAAGCACGGCCGCCCGCGTCACAAGACAAACTGTCGGGGCCGCCC
  GGGNAGGGACCCAATCAGGCTGGTGCGAAATCCGGNCGCCCTTAGTGGAGTCGATACA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006432
• ORF Size: 456 bp
• Insert Size: 850
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006432.3, NP_006423.1
• RefSeq Size: 921
• RefSeq ORF: 456
• Locus ID: 10577
• Domains: ML
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq, Jul 2008]