TSG101 (NM_006292) Human Untagged Clone

CAT#: SC116200

TSG101 (untagged)-Human tumor susceptibility gene 101 (TSG101)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TSG101
• Synonyms: TSG10; VPS23
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006292, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGTGTCGGAGAGCCAGCTCAAGAAAATGGTGTCCAAGTACAAATACAGAGACCTAACTGTACGTG
  AAACTGTCAATGTTATTACTCTATACAAAGATCTCAAACCTGTTTTGGATTCATATGTTTTTAACGATGG
  CAGTTCCAGGGAACTAATGAACCTCACTGGAACAATCCCTGTGCCTTATAGAGGTAATACATACAATATT
  CCAATATGCCTATGGCTACTGGACACATACCCATATAATCCCCCTATCTGTTTTGTTAAGCCTACTAGTT
  CAATGACTATTAAAACAGGAAAGCATGTTGATGCAAATGGGAAGATATATCTTCCTTATCTACATGAATG
  GAAACACCCACAGTCAGACTTGTTGGGGCTTATTCAGGTCATGATTGTGGTATTTGGAGATGAACCTCCA
  GTCTTCTCTCGTCCTATTTCGGCATCCTATCCGCCATACCAGGCAACGGGGCCACCAAATACTTCCTACA
  TGCCAGGCATGCCAGGTGGAATCTCTCCATACCCATCCGGATACCCTCCCAATCCCAGTGGTTACCCAGG
  CTGTCCTTACCCACCTGGTGGTCCATATCCTGCCACAACAAGTTCTCAGTACCCTTCTCAGCCTCCTGTG
  ACCACTGTTGGTCCCAGTAGGGATGGCACAATCAGCGAGGACACCATCCGAGCCTCTCTCATCTCTGCGG
  TCAGTGACAAACTGAGATGGCGGATGAAGGAGGAAATGGATCGTGCCCAGGCAGAGCTCAATGCCTTGAA
  ACGAACAGAAGAAGACCTGAAAAAGGGTCACCAGAAACTGGAAGAGATGGTTACCCGTTTAGATCAAGAA
  GTAGCCGAGGTTGATAAAAACATAGAACTTTTGAAAAAGAAGGATGAAGAACTCAGTTCTGCTCTGGAAA
  AAATGGAAAATCAGTCTGAAAACAATGATATCGATGAAGTTATCATTCCCACAGCTCCCTTATACAAACA
  GATCCTGAATCTGTATGCAGAAGAAAACGCTATTGAAGACACTATCTTTTACTTGGGAGAAGCCTTGAGA
  AGGGGCGTGATAGACCTGGATGTCTTCCTGAAGCATGTACGTCTTCTGTCCCGTAAACAGTTCCAGCTGA
  GGGCACTAATGCAAAAAGCAAGAAAGACTGCCGGTCTCAGTGACCTCTACTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006292 unedited
  AAGTTTTGATTTGTAACCGACTTACTATAGGCGGCCGCGCAATTCGCACGAGGCTGGGGC
  AGCCCAGCAGCGGCTGACCCTCTGCCTGCGGGGAAGGGAGTCGCCAGGCGGCCGTCATGG
  CGGTGTCGGAGAGCCAGCTCAAGAAAATGGTGTCCAAGTACAAATACAGAGACCTAACTG
  TACGTGAAACTGTCAATGTTATTACTCTATACAAATATCTCAAACCTGTTTTGGATTCAT
  ATGTTTTTAACGATGGCAGTTCCAGGGAACTAATGAACCTCACTGGAACAATCCCTGTGC
  CTTATAGAGGTAATACATACAATATTCCAATATGCCTATGGCTACTGGACACATACCCAT
  ATAATCCCCCTATCTGTTTTGTTAAGCCTACTAGTTCAATGACTATTAAAACAGGAAAGC
  ATGTTGATGCAAATGGGAAGATATATCTTCCTTATCTACATGAATGGAAACACCCACAGT
  CAGACTTGTTGGGGCTTATTCAGGTCATGATTGTGGTATTTGGAGATGAACCTCCAGTCT
  TCTCTCGTCCTATTTCGGCATCCTATCCGCCATACCAGGCAACGGGGCCACCAAATACTT
  CCTACATGCCAGGCATGCCAGGTGGAATCTCTCCATACCCATCCGGATACCCTCCCAATC
  CCAGTGGTTACCCAGGCTGTCCTTACCCACCTGGTGGTCCATATCCTGCCACAACAAGTT
  CTCAGTACCCTTCTCAGCCTCCTGTGACCACTGGTTGGTCCCAGTAGGGATGGCANCATC
  AGCGAGGACACCATCCGAGCCTCTCTCATCTCTGCGGGTCAGTGACAACTGAGATGGGCG
  ATGAAAGANGAAATGGATCGTGCCCCAGCAGAGCTCAATGCCTTGNAACGAACAGAAGAA
  GACTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006292 unedited
  ACAGAAGCACGCNNTTCGACNANNCGAGTTCCTCCCCCTCCTCTCTTTTTTTTATGCAAC
  AATGTCTATTTAGCAGTCCCAACATTCAGCACAAAAAGTTTACAGAGGATAGAAAGTGCA
  TTAATAAAAGCCAGTCTTTACCAAAAGAAAACAGAACATATATTATTGATTCAAAATATT
  TTACACTTGAATGATAAACTGCAATAACTTATTCTGGGCACCTACTGATAAAAGGAAGAG
  AAGACTACTTTAAGAACAGCTCAACCTCCAGCTGGTATCAGAGAAGTCAGCAGAGGTCAC
  TGATACCGGTAGTCTTTCTTGCTTTTTGAATTAGTGCCCTCAGCTGGAACTGTTTACGGG
  ACAGAACACGTACATGCTTTAGGAAGACATCCAGGTCTATCACGCCCCTTCTCAAGGCTT
  TTCCCAAGTAAAAGATAGTGTCTTCAATAGCGTTTTCTTCTGCATACAGATCCAGGATCT
  GCCCGCATAAGGCACCCGTGGGACTGATAACTTCATCGATATCATTGCTTTCAGACTGAT
  TTTCCTTCTTTCCCCAACAAACTGAGCCCTTATCCTTCCTTTTCAAAGTTCTATGTTTTA
  ATCAACCTTGGGTACCTTCTGAACCAACCGGGAAACATTCTTTCCAGTTTCTGAGGACTA
  TTTTTAAGGTTTTTTTTGTTTTTTCACGCAATTGAGCTTTCCTGGGACAAACCATTTCTT
  CCTTCCATCCCATTTTAATTTGCCCTTGATTGTTAAATAAAAACCCCTCTATGGTGCCCT
  CCCTGATCGCGCCTCCCTATTGGAAAAAAAGGGCAAAAGAGGCCTAAAGAGTATGAGAAC
  TCGTGGCGCCCGTCCCGGCCCCCACCTGGTACGGCCCCCCGGCAACCCCTGTAATGGGAG
  GCCCCCCGTGGTTTGGATACATCCCCGTCCTGCCGGACTCAAAAATTTTGTGGCCCTCCC
  CCGCTCCGCGCTCCAATTTATATCCACAACACCCCCGCTCCTTCCTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006292
• ORF Size: 1173 bp
• Insert Size: 1560
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006292.2, NP_006283.1
• RefSeq Size: 1550
• RefSeq ORF: 1173
• Locus ID: 7251
• Domains: UBCc
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Endocytosis
• Gene Summary: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]