SEC24B (NM_006323) Human Untagged Clone

CAT#: SC116223

SEC24B (untagged)-Human SEC24 family, member B (S. cerevisiae) (SEC24B), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SEC24B
• Synonyms: SEC24
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006323, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCGGCCCCCGCCGGGTCCTCTCACCCGGCCGCCAGCGCCCGGATCCCGCCCAAGTTCGGCGGAGCGG
  CCGTCTCAGGAGCCGCAGCGCCCGCGGGCCCGGGTGCGGGCCCGGCGCCGCACCAGCAGAACGGTCCAGC
  CCAGAATCAAATGCAGGTTCCATCTGGATATGGATTGCATCATCAAAACTATATTGCTCCCTCAGGACAT
  TACTCTCAAGGACCTGGGAAAATGACCTCATTGCCATTGGATACCCAGTGTGGTGATTACTACTCTGCTC
  TCTATACAGTACCAACACAAAATGTGACTCCTAACACAGTGAACCAGCAACCAGGAGCACAGCAGTTGTA
  CAGCAGGGGTCCTCCTGCCCCTCATATTGTGGGATCCACTCTAGGATCTTTCCAAGGTGCTGCATCGTCA
  GCATCCCATTTGCATACGAGTGCCTCCCAACCATACTCCTCTTTTGTGAATCACTACAATAGTCCAGCCA
  TGTACTCTGCCAGCTCTTCTGTTGCGTCTCAGGGATTTCCCTCTACTTGTGGTCATTATGCTATGTCAAC
  TGTTTCTAATGCCGCGTATCCTAGTGTTTCATATCCCTCTCTGCCTGCTGGTGATACATATGGGCAAATG
  TTTACCTCACAGAATGCTCCGACTGTTAGGCCAGTTAAAGATAATTCATTCTCTGGTCAAAATACAGCTA
  TCAGCCATCCATCGCCACTTCCACCTCTACCATCACAACAGCACCACCAGCAGCAAAGTCTTTCAGGATA
  CAGTACTCTAACGTGGTCATCTCCAGGCCTTCCATCGACTCAAGACAATCTCATCCGAAACCACACAGGA
  TCCCTGGCTGTAGCGAACAACAACCCAACCATTACTGTTGCAGATTCTTTATCCTGTCCTGTTATGCAAA
  ATGTTCAGCCTCCCAAGTCCAGCCCAGTGGTATCCACTGTTTTATCAGGATCCTCAGGATCCTCATCAAC
  AAGAACACCTCCCACTGCAAATCACCCAGTTGAGCCTGTGACCTCAGTTACACAGCCATCAGAGCTATTA
  CAACAAAAAGGCGTGCAGTATGGTGAATATGTTAATAACCAAGCTAGCTCCGCACCAACTCCCTTGTCAT
  CAACTTCCGATGATGAGGAAGAGGAGGAGGAGGATGAGGAAGCAGGTGTTGACAGCTCTTCTACCACAAG
  CAGTGCTTCTCCAATGCCCAACAGTTATGATGCCCTGGAAGGAGGCAGTTACCCAGATATGCTTTCTTCA
  TCAGCAAGCAGTCCTGCTCCTGATCCCGCCCCTGAACCTGATCCTGCTTCTGCTCCAGCTCCAGCTTCAG
  CTCCAGCTCCTGTCGTCCCTCAGCCTTCAAAAATGGCTAAGCCTTTTGGCTATGGCTATCCAACACTTCA
  GCCTGGTTATCAGAATGCTACAGCACCACTTATTTCTGGAGTACAGCCCAGTAACCCGGTATATTCTGGA
  TTCCAGCAGTATCCTCAACAGTATCCTGGTGTGAACCAGCTATCCTCCAGTATAGGAGGATTGAGTCTTC
  AGAGTTCTCCACAACCAGAAAGCCTGAGACCTGTAAACCTTACTCAGGAGAGGAATATTTTACCTATGAC
  TCCTGTTTGGGCTCCTGTACCTAACTTGAATGCAGACCTCAAAAAATTAAACTGTAGCCCAGATTCATTT
  CGGTGTACTTTGACAAATATTCCACAGACACAGGCTTTACTGAATAAAGCTAAGCTTCCTTTAGGATTGT
  TGTTACATCCCTTCAGAGACCTAACGCAATTACCAGTGATAACATCAAATACCATTGTGAGGTGCCGATC
  CTGTCGAACGTATATTAACCCCTTTGTATCCTTCATTGATCAACGTAGATGGAAATGCAATTTGTGCTAT
  AGAGTAAACGATGTTCCTGAAGAATTTATGTATAACCCCCTTACCCGATCTTATGGAGAGCCTCATAAAC
  GACCAGAAGTTCAGAATTCAACTGTGGAGTTCATTGCTTCTTCAGATTACATGCTGCGTCCTCCTCAACC
  TGCAGTTTACTTGTTTGTTTTAGATGTGTCTCATAATGCAGTGGAAGCTGGATATTTGACAATTTTGTGC
  CAGTCACTCCTAGAAAATCTAGACAAGCTTCCTGGAGATTCACGAACAAGAATAGGATTCATGACCTTTG
  ATAGCACTATTCATTTCTACAATTTACAAGAAGGATTATCACAGCCTCAAATGTTGATTGTGTCTGATAT
  AGATGATGTTTTTCTACCTACACCGGATAGTTTACTTGTGAATCTATATGAAAGTAAAGAGCTTATAAAA
  GACTTACTGAATGCATTACCAAACATGTTCACCAATACAAGAGAAACACACAGTGCCCTTGGTCCTGCAC
  TTCAGGCTGCCTTTAAATTAATGTCTCCAACAGGTGGCCGTGTGTCTGTATTTCAGACACAGTTACCTTC
  CTTGGGTGCAGGACTTCTGCAATCCAGAGAAGATCCTAATCAGAGATCAAGTACAAAGGTGGTACAACAT
  CTTGGCCCTGCAACTGATTTTTATAAGAAACTTGCATTAGATTGCTCGGGACAGCAAACTGCAGTGGATT
  TGTTCCTTTTAAGTTCACAGTATTCTGATCTTGCTTCTCTAGCTTGCATGTCCAAGTATTCTGCAGGGTG
  CATCTATTATTATCCATCATTCCACTATACTCACAATCCTTCACAAGCAGAAAAGTTACAAAAAGACCTA
  AAACGGTATCTCACAAGAAAAATTGGGTTTGAAGCTGTTATGAGAATAAGGTGTACTAAAGGTCTTTCAA
  TGCACACTTTTCACGGTAACTTCTTTGTCCGTTCTACTGATTTGTTATCCCTTGCCAACATCAATCCTGA
  TGCTGGATTTGCGGTGCAGTTGTCAATTGAAGAAAGTTTAACAGATACTTCCTTAGTATGTTTTCAAACA
  GCCCTATTATATACATCAAGCAAAGGTGAGCGGAGAATTAGAGTACATACACTTTGTTTGCCAGTGGTAA
  GTTCACTAGCAGATGTATATGCGGGAGTGGATGTACAAGCTGCCATCTGCCTTCTGGCAAACATGGCTGT
  GGATCGGTCCGTTTCATCAAGTCTGTCAGATGCAAGAGATGCCTTAGTGAATGCTGTAGTGGACTCATTG
  TCTGCATATGGCTCAACTGTCTCAAATTTACAGCACTCTGCATTGATGGCGCCCAGCTCCCTCAAGTTGT
  TTCCTCTCTATGTTTTGGCCCTTCTCAAACAGAAAGCATTTAGAACGGGTACAAGCACACGGCTGGATGA
  TCGTGTATATGCCATGTGTCAGATAAAGTCTCAGCCACTTGTTCATCTAATGAAAATGATTCATCCCAAC
  TTATACAGGATAGACAGATTGACAGATGAGGGTGCAGTACATGTTAATGACAGGATTGTACCACAGCCAC
  CTCTTCAAAAATTGTCTGCAGAGAAGCTGACAAGAGAAGGTGCTTTCCTTATGGACTGTGGCTCTGTTTT
  TTACATTTGGGTTGGGAAAGGCTGTGACAATAACTTCATAGAGGATGTGCTTGGATATACTAATTTTGCA
  TCAATACCACAGAAAATGACACATCTTCCAGAGCTAGATACACTTTCATCAGAAAGAGCCAGATCCTTCA
  TAACTTGGCTTAGAGACAGCAGACCATTAAGTCCAATCCTTCACATAGTAAAAGATGAGAGTCCTGCCAA
  AGCAGAATTTTTTCAGCATTTGATTGAAGACCGGACAGAGGCTGCATTTTCTTACTATGAATTTTTGCTT
  CATGTTCAGCAGCAGATTTGTAAGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006323 unedited
  NTTGTTCGAATTTTGGTATACGACTCACTATAGGGCGGCCGGCGATTCGGCACCAGGCCC
  ACCTCCCTGAAGCGGAGCCGCCGTCGCCACCAGCGCCGTCATGTCGGCCCCCGCCGGGTC
  CTCTCACCCGGCCGCCAGCGCCCGGATCCCGCCCAAGTTCGGCGGAGCGGCCGTCTCAGG
  AGCCGCAGCGCCCGCGGGCCCGGGTGCGGGCCCGGCGCCGCACCAGCAGAACGGTCCAGC
  CCAGAATCAAATGCAGGTTCCATCTGGATATGGATTGCATCATCAAAACTATATTGCTCC
  CTCAGGACATTACTCTCAAGGACCTGGGAAAATGACCTCATTGCCATTGGATACCCAGTG
  TGGTGATTACTACTCTGCTCTCTATACAGTACCAACACAAAATGTGACTCCTAACACAGT
  GAACCAGCAACCAGGAGCACAGCAGTTGTACAGCAGGGGTCCTCCTGCCCCTCATATTGT
  GGGATCCACTCTAGGATCTTTCCAAGGTGCTGCATCGTCAGCATCCCATTTGCATACGAG
  TGCCTCCCAACCATACTCCTCTTTTGTGAATCACTACAATAGTCCAGCCATGTACTCTGC
  CAGCTCTTCTGTTGCGTCTCAGGGATTTCCCTCTACTTGTGGTCATTATGCTATGTCAAC
  TGTTTCTAATGCCGCGTATCCTAGTGTTTCATATCCCTCTCTGCCTGCTGGTGATACATA
  TGGGCAAATGTTTACCTCACAGAATGCTCCGACTGGTAGGCCAGTTANAGATAATTCATT
  CTNTGGTCAANATACAGCTATCAGCCATCCATCGCCACTTTCACCTCTACCATCACAACA
  GCACCACCAGCAGCAAGTNCTTTAGGGATACAGACTCTTAACGGTGGTCATTTCCAGGGC
  TTTCATCGACTCCAGACATCTCATTCGAAACACACAGATCCCCTGN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006323 unedited
  CTATGGCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTGTCAAGCGAA
  ATAGTTTTAATTAGTAGGCTGATCATAAATAAATCTACATAAAAGATTTAACAGAATTAC
  AAAGAGTTTTGTGTTCCTTTGTGGACTCAATTCATAATATGCATTAGTCAACCTCATTCT
  CTAACTGTGACAAAAAGAGTTGTCATCCAACAATGCAGCACAGTTTAAGCAATTCATATG
  CTATAGTTACATTTTTACATTTTCTTTACAAATGTAACATTTATGTACATTATATATAGA
  TTTTTTTCTATAGTTCATGTACTGAAACTCTATTGTTTTTACAGAGAAAATGTTGAATTC
  ATTTAATGAATAAGAAACATTCCTTGTTAAAAAGTAATTCATATAAACAAATAACACGGT
  ACCAATGCCTTTTGGCATCTCTTGCCAGAGTTCAAGTCCAGAAATGTTATATTAATTATA
  AGAAAAAAGAATTTATCTAATTTTACATTATGACATATCATTCCACATAGCTACATAAAT
  TTGCCAGCTTGCAATGAACAGAGCACTGTACTGCCATACTACTGGAAATGTGTAGAAACC
  AATTCAAAATATACTTGGTGAAACAGCATCATCGTTACCATTAATTTGAGTTGAAAAAGA
  TCTGTCAAGTTCTTTCTTCCCCTTTACTTTTTACCAAAGCCTCAGACAGAGTGCTGTGCG
  TTGCATCTTGTATTAACAAATGCCTTCATTTCAAATTTCTCACGCGCTTCTCTGACAGAT
  TATGCTTTACCCTAGTTATAGATCTTTTTCTTATTCATTNTATNCTACTTCACTTACAAA
  TCTGCTGCTGAACATGAAGCANAATTCATAGNTAGAAATGCAGCCTCTGTCCGGTCTTCA
  TCAATGCTGAAAAATCTGCTTTGCAGACTCTCATCTTACTAGTGAAGATGNACTTAATGT
  CTGTGCCTTAGCCAGTATGAAGAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006323
• ORF Size: 3807 bp
• Insert Size: 4860
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006323.1, NP_006314.1
• RefSeq Size: 4758
• RefSeq ORF: 3807
• Locus ID: 10427
• Domains: zf-Sec23_Sec24, Sec23_trunk, Sec23_helical, Gelsolin
• Gene Summary: The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein is thought to be a cargo-binding component of the COPII vesicle, and is thought to be involved in the transport of secretory proteins from the endoplasmic reticulum to the Golgi apparatus. Mutations in this gene have been associated with neural tube defects, and are thought to be a result of a disruption in interactions with the protein encoded by the VANGL planar cell polarity protein 2 (VANGL2) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
  Transcript Variant: This variant (1) lacks an in-frame exon in the 5' coding region and uses an alternate in-frame splice site in the central coding region, compared to variant 3. The encoded isoform (a) is shorter, compared to isoform c.