GM CSF Receptor alpha (CSF2RA) (NM_006140) Human Untagged Clone

CAT#: SC116268

CSF2RA (untagged)-Human colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (CSF2RA), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CSF2RA
• Synonyms: alphaGMR; CD116; CDw116; CSF2R; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; GM-CSF-R-alpha; GMCSFR; GMR; SMDP4
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116268 sequence for NM_006140 edited (data generated by NextGen Sequencing)
  ATGCTTCTCCTGGTGACAAGCCTTCTGCTCTGTGAGTTACCACACCCAGCATTCCTCCTG
  ATCCCAGAGAAATCGGATCTGCGAACAGTGGCACCAGCCTCTAGTCTCAATGTGAGGTTT
  GACTCCAGGACGATGAATTTAAGCTGGGACTGCCAAGAAAACACAACCTTCAGCAAGTGT
  TTCTTAACTGACAAGAAGAACAGAGTCGTGGAACCCAGGCTCAGTAACAACGAATGTTCG
  TGCACATTTCGTGAAATTTGTCTGCATGAAGGAGTCACATTTGAGGTTCACGTGAATACT
  AGTCAAAGAGGATTTCAACAGAAACTGCTTTATCCAAATTCAGGAAGGGAGGGTACCGCT
  GCTCAGAATTTCTCCTGTTTCATCTACAATGCGGATTTAATGAACTGTACCTGGGCGAGG
  GGTCCGACGGCCCCCCGTGACGTCCAGTATTTTTTGTACATACGAAACTCAAAGAGAAGG
  AGGGAGATCCGGTGTCCTTATTACATACAAGACTCAGGAACCCATGTGGGATGTCACCTG
  GATAACCTGTCAGGATTAACGTCTCGCAATTACTTTCTGGTTAACGGAACCAGCCGAGAA
  ATTGGCATCCAATTCTTTGATTCACTTTTGGACACAAAGAAAATAGAACGATTCAACCCT
  CCCAGCAATGTCACCGTACGTTGCAACACGACGCACTGCCTCGTACGGTGGAAACAGCCC
  AGGACCTATCAGAAGCTGTCGTACCTGGACTTTCAGTACCAGCTGGACGTCCACAGAAAG
  AATACCCAGCCTGGCACGGAAAACCTACTGATTAATGTTTCTGGTGATTTGGAAAATAGA
  TACAACTTTCCAAGCTCTGAGCCCAGAGCAAAACACAGTGTGAAGATCAGAGCTGCAGAC
  GTCCGCATCTTGAATTGGAGCTCCTGGAGTGAAGCCATTGAATTTGGTTCTGACGACGGG
  AACCTCGGCTCTGTGTACATTTATGTGCTCCTAATCGTGGGAACCCTTGTCTGTGGCATC
  GTCCTCGGCTTCCTCTTTAAAAGGTTCCTTAGGATACAGCGGCTGTTCCCGCCAGTTCCA
  CAGATCAAAGACAAACTGAATGATAACCATGAGGTGGAAGACGAGATCATCTGGGAGGAA
  TTCACCCCAGAGGAAGGGAAAGGCTACCGCGAAGAGGTCTTGACCGTGAAGGAAATTACC
  TGA
  
  Clone variation with respect to NM_006140.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006140 unedited
  GTCAGGATATGTAAACGACTTACTATAGGGCGGCCGCGCAATTCGCACGAGGAAAAGCGG
  TGGAAGGAGAGGAAGCGGATGCCGTGGGGTTTACAGCAGGGAAAATCCGTGGAGACAGCA
  GATCCGAGAAGCGGCGATGTTTGCGTAGAACCCTGTACGTGCTTCCTTCGGCCTGTCGCT
  CTTCCCTTCTCTCTGACCAGCACCATGCTTCTCCTGGTGACAAGCCTTCTGCTCTGTGAG
  TTACCACACCCAGCATTCCTCCTGATCCCAGAGAAATCGGATCTGCGAACAGTGGCACCA
  GCCTCTAGTCTCAATGTGAGGTTTGACTCCAGGACGATGAATTTAAGCTGGGACTGCCAA
  GAAAACACAACCTTCAGCAAGTGTTTCTTAACTGACAAGAAGAACAGAGTCGTGGAACCC
  AGGCTCAGTAACAACGAATGTTCGTGCACATTTCGTGAAATTTGTCTGCATGAAGGAGTC
  ACATTTGAGGTTCACGTGAATACTAGTCAAAGAGGATTTCAACAGAAACTGCTTTATCCA
  AATTCAGGAAGGGAGGGTACCGCTGCTCAGAATTTCTCCTGTTTCATCTACAATGCGGAT
  TTAATGAACTGTACCTGNGCGAAGGGTCCGACGGCCCCCCGTGACGTCCAGTATTTTTTG
  TACATACGAAACTCAAAGAGAAGGAAGGAGATCCCGTGTCCTTATTACATACAAGACTCA
  NGAACCCATGTGGGATGTCACCTGGATAACCTGTCCAGATTAACGTCTCGCAATTACTTT
  CTGGTTAAGGAACCAGCCGAGAAATGGCATCCAATTCTTTGATTCACTTTCGGCACAAAG
  AAAATGAACGATTCACCCTCCCAGCATGTCACCGTACGTTGAACACCACGCCTGCCCGTA
  CGGTGAAACAGCCCAGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006140 unedited
  TAGAGTCGAGNNNTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTCCCCACCCAAATATCAGGGGTTTAATAATTAATAATAATGGGGGGTTTGGAAAAG
  CAATTTTGCTTTGTCACCCAGGTTGGGGGGCAATGGGGCAATTTTGGTTAACTACAACCT
  CCGCCTAAGGGGTTAAAGCAATTTTCCTGCCTCACCCTCCCAAGTACCTGGGATGATGGG
  CGTCCCCCCCCGGGCCTGGGAAAATTTCTGCATTTTTAGCCCAAAGGGGGTTTCACCATG
  TGGGGCAGGCTGGTCTTGAACTCCTGACCTAAGGGGATCCCCCTGCCTTGGCCTCCCAAA
  GGGCTGGGATTACAGGCGTGACCCACCGCCCCTGGCCCCAAATGTCATGTTTTTAAATAA
  AACCTTAAAAAATGATTTAAGGGTTCCCAGCTTCTTCAAAAAAACAGTTCCTCCGTGTCC
  CGGAGGCGGAAATGTCCATGCCATTCCTACACCCTTTGGGTCTCAGGTAATTTCCTTCAC
  GGACAAGACCTCTTCGGGGAACCCTTTCCCTTCCTGTGGGGTGAATTCCTCCCAAAGATC
  CCGTCTTCCCCTCAGGGTTATATTCANTTTGCCTTGATCTGGGAACTGGCGGAACACCCG
  CTGATCCTAAGAACCTTTAAAGAGGAACCCAGGACCATCCCCCAAAAGGGTTCCCACATT
  AGACCCATAATGTCACAAACCCGGGTTCCCGTTGTAAACCCAATTAAGGTTTACTCCAGG
  ACCCCATTTAAGAGCGGCCGTTGCATTTTGATCTCACATTGGTTTTGCTCGGGCTAAAAC
  TTGAAATTTTTTCTTTTCCAACACAAAAACATTATAAAGGTTCCCGGCCCCTTGGATTTT
  TTTGGGCCTCCCTTGTCCTGAACAGAACCAAATCTTTATGGCTGGCGTGTCCCCCAAAGG
  AGGCGTTGGTTCACAAGGGAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006140
• Insert Size: 1910 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006140.3, NP_006131.2
• RefSeq Size: 1844 bp
• RefSeq ORF: 1203 bp
• Locus ID: 1438
• Cytogenetics: X;Y
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Pathways in cancer
• Gene Summary: 'The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) and variants 2 and 7 encode the same isoform (a), which is membrane-bound.