SIRPB1 (NM_006065) Human Untagged Clone

CAT#: SC116388

SIRPB1 (untagged)-Human signal-regulatory protein beta 1 (SIRPB1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SIRPB1
• Synonyms: CD172b; SIRP-BETA-1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006065 edited
  GAATTCGGCACGAGAGACGTTTGGACAGAGCAGGCTCCTAAGGTCTCCAGAATGCCCGTG
  CCAGCCTCCTGGCCCCACCTTCCTAGTCCTTTCCTGCTGATGACGCTACTGCTGGGGAGA
  CTCACAGGAGTGGCAGGTGAGGACGAGCTACAGGTGATTCAGCCTGAAAAGTCCGTATCA
  GTTGCAGCTGGAGAGTCGGCCACTCTGCGCTGTGCTATGACGTCCCTGATCCCTGTGGGG
  CCCATCATGTGGTTTAGAGGAGCTGGAGCAGGCCGGGAATTAATCTACAATCAGAAAGAA
  GGCCACTTCCCACGGGTAACAACTGTTTCAGAACTCACAAAGAGAAACAACCTGGACTTT
  TCCATCAGCATCAGTAACATCACCCCAGCAGACGCCGGCACCTACTACTGTGTGAAGTTC
  CGGAAAGGGAGCCCTGACGACGTGGAGTTTAAGTCTGGAGCAGGCACTGAGCTGTCTGTG
  CGCGCCAAACCCTCTGCCCCCGTGGTATCGGGCCCTGCGGTGAGGGCCACACCTGAGCAC
  ACAGTGAGCTTCACCTGCGAGTCCCATGGCTTCTCTCCCAGAGACATCACCCTGAAATGG
  TTCAAAAATGGGAATGAGCTCTCAGACTTCCAGACCAACGTGGACCCCGCAGGAGACAGT
  GTGTCCTACAGCATCCACAGCACAGCCAGGGTGGTGCTGACCCGTGGGGACGTTCACTCT
  CAAGTCATCTGCGAGATGGCCCACATCACCTTGCAGGGGGACCCTCTTCGTGGGACTGCC
  AACTTGTCTGAGGCCATCCGAGTTCCACCCACCTTGGAGGTTACTCAACAGCCCATGAGG
  GCAGAGAACCAGGCAAACGTCACCTGCCAGGTGAGCAATTTCTACCCCCGGGGACTACAG
  CTGACCTGGTTGGAGAATGGAAATGTGTCCCGGACAGAAACAGCTTCGACCCTCATAGAG
  AACAAGGATGGCACCTACAACTGGATGAGCTGGCTCCTGGTGAACACCTGTGCCCACAGG
  GACGATGTGGTGCTCACCTGTCAGGTGGAGCATGATGGGCAGCAAGCAGTCAGCAAAAGC
  TATGCCCTGGAGATCTCAGCACACCAGAAGGAGCACGGCTCAGATATCACCCATGAACCA
  GCGCTGGCTCCTACTGCTCCACTCCTCGTAGCTCTCCTCCTGGGCCCCAAGCTGCTACTG
  GTGGTTGGTGTCTCTGCCATCTACATCTGCTGGAAACAGAAGGCCTGACTGACCCTCAGT
  CTCTGCTGCCTCCTCCTTTCTTGAGAAGCTCAGCCTGAGAGAAGGAGCTGGCGAGAACCT
  TCCCCACACTCAGCTCCAAACGCCTCCTCTCCCAGGTCATCTGCCTGCCCACACGCTCCT
  GTTCCACCTTCACAAGACCATGATGCCCCAAAGCAGTGTCTCTATTCACGGTCCTGAGCA
  GGGGCCATGGGATTGGGCTCTGGGCACTGACTCATGGCACCTCCCTAGAAGGTGAGAAAC
  ACTCCAAATCTAAACACACCAGGACTTCTCCCATCCGTCGCCTTGGGACTGGCCATAAAC
  CACAGACTCTCTCCAGGCTCTCAAGAGTTATCCTGTCTTCTGGATTCCTGCCTACCCCAA
  CTCCCCCAGCCTTGTTGAGGTTCTCTACTGCCTCCTGAATACACATGAACCCCTATACCA
  ATTTTAAGAAAAAAATGATTCTCTTTCCTCTTTGTCCAAGCATCCTATCCCTCAAACCCA
  AAAAGAAAGAAGCTCTCCCTTCTCTCTCTGTGATGGGGACAGTATTTCTTCTAGTATCCT
  GCAGCCTTCCCAGTCCTGCTGCTTGTGGTAGAAATGCTGCCACAGCCCAACATTGAGGAG
  CCCTCGATGACTGCCCTTTACAACTCATATTCAGTTCTGCCTCCAAAATGCATGTGTCCA
  CTTACGTGAGATGGTAAATGTTTAACAATGGACTTTCTGAAAGGGAAAAACCAAAAGCTG
  TTTTGCAGTGCTTGCCAATTTCXXXXXXXXXXXXXXAATTTAACAATTGGTTTTCAGGGC
  CCAGTCCAAGCCTGNTGCTGGAAACCTCAGAGTTAAATCCCTATTCTCCACACCTCTCAC
  CTCCACCACCCCTCCCTGTCCCAGCCAGCATCATCTCTTTGGGGACCACTCCTCTGGCTT
  TCATTTTTCAGCCACAGTGATTCTTTGGAAAAGTCAAATCATATCACTTCTCTGCTTCTT
  CCCCAACACAGCTGCATGGCTCCCGCTCTCCCTCCTTCAAGTCTCTGCTCAATGTCACTT
  CATTAAAGGCACCTTCTATAAACTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  ACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006065 unedited
  AGTATTTTGTAATACGACTCACTTATAGGGCGGCCGCGAATTCGCACGAGAAACGTTTGG
  ACAGAGCAGGCTCCTAAGGTCTCCAGAATGCCCGTGCCAGCCTCCTGGCCCCACCTTCCT
  AGTCCTTTCCTGCTGATGACGCTACTGCTGGGGAGACTCACAGGAGTGGCAGGTGAGGAC
  GAGCTACAGGTGATTCAGCCTGAAAAGTCCGTATCAGTTGCAGCTGGAGAGTCGGCCACT
  CTGCGCTGTGCTATGACGTCCCTGATCCCTGTGGGGCCCATCATGTGGTTTAGAGGAGCT
  GGAGCAGGCCGGGAATTAATCTACAATCAGAAAGAAGGCCACTTCCCACGGGTAACAACT
  GTTTCAGAACTCACAAAGAGAAACAACCTGGACTTTTCCATCAGCATCAGTAACATCACC
  CCAGCAGACGCCGGCACCTACTACTGTGTGAAGTTCCGGAAAGGGAGCCCTGACGACGTG
  GAGTTTAAGTCTGGAGCAGGCACTGAGCTGTCTGTGCGCGCCAAACCCTCTGCCCCCGTG
  GTATCGGGCCCTGCGGTGAGGGCCACACCTGAGCACACAGTGAGCTTCACCTGCGAGTCC
  CATGGCTTCTCTCCCAGAGACATCACCCTGAAATGGTTCAAAAATGGGAATGAGCTCTCA
  GACTTCCAGACCAACGTGGACCCCGCAGGAGACAGTGTGTCCTACAGCATCCACAGCACA
  GCCAGGGGTGGGTGCTGACCCGTGGGGGACGTTCACTCTCAAGTCATCTGCGAGATGGCC
  CACATCACCTTGCAGGGGGACCCTCTTCGTGGGACTGCCAACTTGTCTGAGGCCATNCGA
  GTTCCCCCACCTTGGNAGGTACTCACAGCCCATGAGGGCAGAGAACCAGGCAACGTCACT
  GCCAGTGAGCATTTCTACCCCGGGGACTACACTGACCTGGTTGAGATGGNAAATNGTCCN
  GNACGAAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006065 unedited
  GGGGGGGGGGCCACAAACCCAATCTTTTTNNNNNNANNNNTTACTGTGNNACGCGGNNCC
  GCATTCTNANGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAGTTTA
  TAAAAGGGGCCTTTAATGAAGTGACATTGAGCAGAAACTTGAAGGAGGGAGAGCGGGAGC
  CATGCATCTGTGTTGGGGAAAAAGCAGAAAAGTGATATGATTTGACTTTTCCAAAAAATC
  ACTGGGGCTGAAAAATGAAAGCCAGAGGAGTGGTCCCCAAAAAAATGATGCTGGCTGGGA
  CAGGGAGGGGTGGTGGAGGTGAAAGGTGTGGAAAATAGGGATTTAACTTTGAGGTTTCCA
  GCAACAGGCTTGGACTGGGCCCTGAAAACCAATTGTTAAATTTCAGGAATCTTGCAATCT
  GGTTGTTTAACTGTTGGCAGTGTGAAATTGGTCAGGTTGGGAGTTATTACACTAGAGAAA
  TTGGCAAGCACTGCAAAACAGCTTTTGGTTTTTCCCTTTCAGAAAGTCCATTGTTAAACA
  TTTACCATCTCACGTAAGTGGACACATGCATTTTGGAGGCAGAACTGAATATGAGTTGTA
  AAGGGCAGTCATCGAGGGCTCCTCAATGTTGGGCTGTGGCAGCATTTCTACCACAAGCAA
  AATGACTGGGAAGGCTGCAGGATACTAAAAGAAATCTGTTCCCATCACAAAAAGAGAAGG
  AGAGCTCTTTTCTTTTTGGTTTTGAGGCATACGATGCTTGGACAAAAAGAAAGGAGATCC
  TTTTTTTCTTCAAAATGGAATTGGGGTCCATGTTTTTTCAGAGGCCACTAAAAAACCTCA
  CAAGGTTGGGGGATTTGGGTTAGCCAGGATTCCAAAAAAAGGTAACCCTTTGAACCTGGA
  AAAAATTGGGGTTTTTGGCCACTCCAAAGCCAACGTTGGGAAAAACCTTGTGGGGTTTAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006065
• ORF Size: 1197 bp
• Insert Size: 2380
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006065.1, NP_006056.1
• RefSeq Size: 3804
• RefSeq ORF: 1197
• Locus ID: 10326
• Domains: ig, IGc1, IG
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Isoforms 1 and 3 are the same length but differ in their amino acid sequences.