COX17 (NM_005694) Human Untagged Clone

CAT#: SC116566

COX17 (untagged)-Human COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) (COX17), nuclear gene encoding mitochondrial protein

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: COX17
• Synonyms: MGC104397; MGC117386
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116566 sequence for NM_005694 edited (data generated by NextGen Sequencing)
  ATGCCGGGTCTGGTTGACTCAAACCCTGCCCCGCCTGAGTCTCAGGAGAAGAAGCCGCTG
  AAGCCCTGCTGCGCTTGCCCGGAGACCAAGAAGGCGCGCGATGCGTGTATCATCGAGAAA
  GGAGAAGAACACTGTGGACATCTAATTGAGGCCCACAAGGAATGCATGAGAGCCCTAGGA
  TTTAAAATATGA
  
  Clone variation with respect to NM_005694.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005694 unedited
  GCACGAGGGACTGCCGGAAGTGACTGCGGACGAATCGGCGTTTGCCGAGGCTGGCATAGA
  TTTGGCTGTCTCCGCTCATAGCTGCTTTTGGCGCGAAAGATGCCGGGTCTGGTTGACTCA
  AACCCTGCCCCGCCTGAGTCTCAGGAGAAGAAGCCGCTGAAGCCCTGCTGCGCTTGCCCG
  GAGACCAAGAAGGCGCGCGATGCGTGTATCATCGAGAAAGGAGAAGAACACTGTGGACAT
  CTAATTGAGGCCCACAAGGAATGCATGAGAGCCCTAGGATTTAAAATATGAAATGGTGGT
  CTGCTGTGTGAATAAATAATTCCTGAAGAATGAAGAAGATTAATTTTGGGAGTTCTTTGA
  CGAACTTTGATATGTGGAAAAAGTATTTATAATTTATTGTAAGAAGAAAGTAAAATATTA
  CTAGTGGAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTT
  TCCTGAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTG
  GAAGTTGCCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATTAAGTTGCATCATTTTG
  TCTGACTAGGTGTCCTTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005694 unedited
  GACGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCCACTAGTAATATTTTA
  CTTTCTTCTTACAATAAATTATAAATACTTTTTCCACATATCAAAGTTCGTCAAAGAACT
  CCCAAAATTAATCTTCTTCATTCTTCAGGAATTATTTATTCACACAGCAGACCACCATTT
  CATATTTTAAATCCTAGGGCTCTCATGCATTCCTTGTGGGCCTCAATTAGATGTCCACAG
  TGTTCTTCTCCTTTCTCGATGATACACGCATCGCGCGCCTTCTTGGTCTCCGGGCAAGCG
  CAGCAGGGCTTCAGCGGCTTCTTCTCCTGAGACTCAGGCGGGGCAGGGTTTGAGTCAACC
  AGACCCGGCATCTTTCGCGCCAAAAGCAGCTATGAGCGGAGACAGCCAAATCTATGCCAG
  CCTCGGCAAACGCCGATTCGTCCGCAGTCACTTCCGGCAGTCCCTCGTGCCGAATTCGCG
  GCCGCCCTATAGTGAGTCGTATTACAAAATTCTGACGGTTCACTAAACGAGCTCTGCTTA
  TATAGACCTCCCACCGTACACGCCTACCGCCCATTTGCGTCAACGGGGCGGGGTTATTAC
  GACATTTTGGAAAGTCCCGTTGATTTTGGTGCCAAAACAAACTCCCATTGACGTCAATGG
  GGGTGGAGACTTGGAAATCCCCGTGAGTCAAACCGCTATCCACGCCCATTGGTGTACTGC
  CAAAACCGCATCACCATGGTAATAGCGATGACTAATACGTAGATGTACTGCCAAGTANGA
  AAGTCCCGTAAGTCATGTACTGGGCATAATGCCAGGCGGGCCATTTACCGTCATTGACGT
  CCATAGGGGGGCCGACCTGGCATATGATACACTTGATGTACTGCCAAGTGGGCAGTTTAC
  CGTAATACTCCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005694
• ORF Size: 192 bp
• Insert Size: 460
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_005694.1, NP_005685.1
• RefSeq Size: 423
• RefSeq ORF: 192
• Locus ID: 10063
• Protein Pathways: Metabolic pathways, Oxidative phosphorylation
• Gene Summary: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. [provided by RefSeq, Jul 2008]