ELOC (NM_005648) Human Untagged Clone

CAT#: SC116611

TCEB1 (untagged)-Human transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) (TCEB1), transcript variant 1


  "NM_005648" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ELOC
Synonyms SIII; TCEB1
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_005648 edited
ATGGATGGAGAGGAGAAAACCTATGGTGGCTGTGAAGGACCTGATGCCATGTATGTCAAA
TTGATATCATCTGATGGCCATGAATTTATTGTAAAAAGAGAACATGCATTAACATCAGGC
ACGATAAAAGCCATGTTGAGTGGCCCAGGTCAGTTTGCTGAGAACGAAACCAATGAGGTC
AATTTTAGAGAGATACCTTCACATGTGCTATCGAAAGTATGCATGTATTTTACGTACAAG
GTTCGCTACACTAACAGCTCCACCGAGATTCCTGAATTCCCAATTGCACCTGAAATTGCA
CTGGAACTGCTGATGGCTGCGAACTTCTTAGATTGTTAA
>OriGene 5' read for NM_005648 unedited
GTTCAGATTTGTATACGACTCCTATAGGGCGGCCGCGAATCGGCACGAGGCCCGGACAGG
CAGCTGGGGGTGGGGGGGCGGCCCTGGGATAGGGGCTGTGGCAGTACGCGGGGACCCGGC
TGCGGTGGCTGCGGGACTGACGAGAAACTACTAAAGTTCCTGGGGAAGCAAAGTAGAATT
TCATAAGAACAAAATGGATGGAGAGGAGAAAACCTATGGTGGCTGTGAAGGACCTGATGC
CATGTATGTCAAATTGATATCATCTGATGGCCATGAATTTATTGTAAAAAGAGAACATGC
ATTAACATCAGGCACGATAAAAGCCATGTTGAGTGGCCCAGGTCAGTTTGCTGAGAACGA
AACCAATGAGGTCAATTTTAGAGAGATACCTTCACATGTGCTATCGAAAGTATGCATGTA
TTTTACGTACAAGGTTCGCTACACTAACAGCTCCACCGAGATTCCTGAATTCCCAATTGC
ACCTGAAATTGCACTGGAACTGCTGATGGCTGCGAACTTCTTAGATTGTTAAATAAAATA
AATTATAATAAACTGTTAACTCTTTTCAGTATTTAATACCTGTAGTTCAGTTAGTAACTT
TTTCATATATAGCATGTTGCCTGTATGCAGTTGAACTATATAAAGTTCATTGCAAAGCAG
ATTATCTTGTTTTTTTGCATAGCAATCAAAGTTGAAATTTGTTTGCTACATCAACAAATT
AAGGACCATTTCACAAACTGAGAAATAAACCAATATGCCAATTAAAAAAAAAAAAAAAAA
CTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCTGGACAGATCCCGTTGGCATCC
CTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTGNNAGTTGCCACTCCAGTGCCACCAGC
CTTGT
>OriGene 3' read for NM_005648 unedited
CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAATTGGCATATTTGTTTA
TTTCTCAGTTTGTGAAAATGTCCTTAATTTGTTGATGTAGCAAACAAATTTCAACTTTGA
TTGCTATGCAAAAAAACAAGATAATCTGCTTTGCAATGAACTTTATATAGTTCAACTGCA
TACAGGCAACATGCTATATATGAAAAAGTTACTAACTGAACTACAGGTATTAAATACTGA
AAAGAGTTAACAGTTTATTATAATTTATTTTATTTAACAATCTAAGAAGTTCGCAGCCAT
CAGCAGTTCCAGTGCAATTTCAGGTGCAATTGGGAATTCAGGAATCTCGGTGGAGCTGTT
AGTGTAGCGAACCTTGTACGTAAAATACATGCATACTTTCGATAGCACATGTGAAGGTAT
CTCTCTAAAATTGACCTCATTGGTTTCGTTCTCAGCAAACTGACCTGGGCCACTCAACAT
GGCTTTTATCGTGCCTGATGTTAATGCATGTTCTCTTTTTACAATAAATTCATGGCCATC
AGATGATATCAATTTGACATACATGGCATCAGGTCCTTCACAGCCACCATAGGTTNTCTC
CTCTCCATCCATTTTGTTCTTATGAAATTCTACTTTGCTTCCCCAGGAACTTTAGTAGTT
TCTCGTCAGTCCCGCAGCCACCGCAACCGGGTCCCCGCGTACTGCCACAGNCCCTATCCC
ATGGCCGCCCCCCCACCCCCAATTGTCTGCTCCCGCCTCGTGCCGAATTTCGGGCCGCCC
TATATTGAGTCGAATACAAAATCCTGACGGNTCACTAAACGACCTCTGCTTAATAAACCT
CCACCGTACACGCTACCGCCCTTTGGGTAACGGGGCGGGGTATTACAACATTTGGAAGTC
CGGTGGTTTGGCGCCAAAAAAACTCCCTTGCCGCAATGGGGTGGGAACCTGG
Restriction Sites NotI-NotI     
ACCN NM_005648
Insert Size 800 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_005648.2, NP_005639.1
RefSeq Size 668 bp
RefSeq ORF 339 bp
Locus ID 6921
Cytogenetics 8q21.11
Domains Skp1
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Pathways in cancer, Renal cell carcinoma, Ubiquitin mediated proteolysis
Gene Summary 'This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011]'
Transcript Variant: This variant (1) represents the predominant transcript. Variants 1-7 encode the same protein (isoform a).

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