TRF2 (TERF2) (NM_005652) Human Untagged Clone

CAT#: SC116614

TERF2 (untagged)-Human telomeric repeat binding factor 2 (TERF2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TERF2
• Synonyms: TRBF2; TRF2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116614 sequence for NM_005652 edited (data generated by NextGen Sequencing)
  ATGGCGGGAGGAGGCGGGAGTAGCGACGGCAGCGGGCGGGNAGCTGGCAGGCGGGCGTCC
  CGCAGTAGCGGGCGGGCCCGGCGGGGGCGCCACGAGCCGGGGCTGGGGGGCCCGGCGGAG
  CGCGGCGCGGGGGAGGCACGGCTGGAAGAGGCAGTCAATCGCTGGGTGCTCAAGTTCTAC
  TTCCACGAGGCGCTGCGGGCCTTTCGGGGTAGCCGGTACGGGGACTTCAGACAGATCCGG
  GACATCATGCAGGCTTTGCTTGTCAGGCCCTTGGGGAAGGAGCACACCGTGTCCCGATTG
  CTGCGGGTTATGCAGTGTCTGTCGCGGATTGAAGAAGGGGAAAATTTAGACTGTTCCTTT
  GATATGGAGGCTGAGCTCACACCACTGGAATCAGCTATCAATGTGCTGGAGATGATTAAA
  ACGGAATTTACACTGACAGAAGCAGTGGTCGAATCCAGTAGAAAACTGGTCAAGGAAGCT
  GCTGTCATTATTTGTATCAAAAACAAAGAATTTGAAAAGGCTTCAAAAATTTTGAAAAAA
  CATATGTCCAAGGACCCCACAACTCAGAAGCTGAGAAATGATCTCCTGAATATTATTCGA
  GAAAAGAACTTGGCCCATCCTGTTATCCAGAACTTTTCATATGAGACCTTCCAGCAGAAG
  ATGCTGCGCTTCCTGGAGAGCCACCTGGATGACGCCGAGCCCTACCTCCTCACGATGGCC
  AAAAAGGCTTTGAAATCTGAGTCCGCTGCCTCAAGTACAGGGAAGGAAGATAAACAGCCA
  GCACCAGGGCCTGTGGAAAAGCCACCCAGAGAACCCGCAAGGCAGCTACGGAATCCTCCA
  ACCACCATTGGAATGATGACTCTGAAAGCAGCTTTCAAGACTCTGTCTGGTGCACAGGAT
  TCTGAGGCAGCCTTTGCAAAACTGGACCAGAAGGATCTGGTTCTTCCTACTCAAGCTCTC
  CCAGCATCACCAGCCCTCAAAAACAAGAGACCCAGAAAAGATGAAAACGAAAGTTCAGCC
  CCGGCTGACGGTGAGGGTGGCTCGGAACTGCAGCCCAAGAACAAGCGCATGACAATAAGC
  AGATTGGTCTTGGAGGAGGACAGCCAGAGTACTGAGCCCAGCGCAGGCCTCAACTCCTCC
  CAGGAGGCCGCTTCAGCGCCACCATCCAAGCCCACCGTTCTCAACCAACCCCTCCCTGGA
  GAGAAGAATCCCAAAGTACCCAAAGGCAAGTGGAACAGCTCTAATGGGGTTGAAGAAAAG
  GAGACTTGGGTGGAAGAGGATGAACTGTTTCAAGTTCAGGCANCACCAGATGAAGACAGT
  ACAACCAATATAACAAAAAAGCAGAAGTGGACTGTAGAAGAAAGCGAGTGGGTCAAGGCT
  GGAGTGCAGAAATATGGGGAAGGAAACTGGGCTGCCATTTCTAAAAATTACCCATTTGTT
  AACCGAACAGCTGTGATGATTAAGGATCGCTGGCGGACCATGAAAAGACTTGGCATGAAC
  TGA
  
  Clone variation with respect to NM_005652.3
  41 c=>n;1303 g=>n
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005652 unedited
  ATTTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCGGCCGGGAGGGC
  GGGGAGGGCGCGCGGCGATCGGACACGATGGCGGGAGGAGGCGGGAGTAGCGACGGCAGC
  GGGCGGGCAGCTGGCAGGCGGGCGTCCCGCAGTAGCGGGCGGGCCCGGCGGGGGCGCCAC
  GAGCCGGGGCTGGGGGGCCCGGCGGAGCGCGGCGCGGGGGAGGCACGGCTGGAAGAGGCA
  GTCAATCGCTGGGTGCTCAAGTTCTACTTCCACGAGGCGCTGCGGGCCTTTCGGGGTAGC
  CGGTACGGGGACTTCAGACAGATCCGGGACATCATGCAGGCTTTGCTTGTCAGGCCCTTG
  GGGAAGGAGCACACCGTGTCCCGATTGCTGCGGGTTATGCAGTGTCTGTCGCGGATTGAA
  GAAGGGGAAAATTTAGACTGTTCCTTTGATATGGAGGCTGAGCTCACACCACTGGAATCA
  GCTATCAATGTGCTGGAGATGATTAAAACGGAATTTACACTGACAGAAGCAGTGGTCGAA
  TCCAGTAGAAAACTGGTCAAGGAAGCTGCTGTCATTATTTGTATCAAAAACAAAGAATTT
  GAAAAGGCTTCAAAAATTTTGAAAAAACATATGTCCAAGGACCCCACAACTCAGAAGCTG
  AGAAATGATCTCCTGAATATTATTCGAGAAAAGAACTTGGCCCATCCTGTTATCCAGAAC
  TTTTTATATGAGACCTTCCAGCAGAAGATGCTGCGCTTCCTGGAGAGCCACCTGGATGAC
  GCCGAGCCCTACCTCCTCACGATGGCCAAAAAGGCTTTGAAATCTGAGTCCGCTGCCTCA
  AGTACGGGAANGGAGATAAACAGNCAGCACCAGGCCTGTGGAAAAGCCCCCAGAGAACCG
  CCAGGCAGCTAACGGATCCTTCAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005652 unedited
  CCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAGAGAACAAGACTTTAATG
  AAGAATGCTACAAGTATGGACAATAATTAGTTCTCACCTTTTAAAAAAAGATACAGAAAA
  CACTTTACTGAAATTTTTTGCTAAAAAGACAGTCTTTAAGGGTGTCCGGGAGAGACAGCA
  AGCACAACACAGTACAAAAGGAGAAGGGAATGTTGAATTCCAGTGCAAGACACGAACACA
  GCACAATTAGGGAATCAGGAGGAAGCAACCATTTCACAAAGAATGAAATTAGGCATTTAT
  ATTCAATCGGATTTTTTTTAAGCTTTAAAAGTCCAGCATAAGGAAGGGAATTGGGAAAAG
  AGGCAGGGGACAGGGGGCAGGGGATCAGGGAACTAATCTTATCTACAATCACCATTTTAC
  CAAAAAACACACTGGTTCAACCACATGAGAAGTGGAGGATTAACCTGCCTACATAGCCCA
  GCAGATGTTGACAGCAAATGCCAAGGCAGACAGGTCTAGGGTTGATGTCACGACTGGCTA
  AAGAGTTTTTAAAGGGAATCTTATTCCACAAGGACTGGTCTGTCATCAACCTGNGTTCAT
  AACAGACTAAGTTCCTTTGCATTTGCATCAGAAGGCCAGAACTTGACGTGGAACANAATT
  ACTCCAAATAATACTCACATTGCTGGTTNTAACAGGTCATGGAGTCACAAGTGGCTCCTA
  ATAGACTTCACCATTTCCTANGAGAAGGTTCTACAGATTACCAGGGATTTAAATTTAAGC
  CAACCCACTAAGAANGGGAACGCTAATGATATTCTGGCACTGCACAAGCTGTGTGCCTGT
  CATCTCTGCCAAGGACATGGGTTGGGACTGGNCTCTGCTTCCTACCTCCATGATCTCCAC
  CGTGATGAAGTGGAATGGGACCCTCCCCAGTCGAAGGAGGTCGCCAAAATCTTATCCCAC
  CCCACTCTTGAAGGACG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005652
• Insert Size: 3000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005652.2, NP_005643.1
• RefSeq Size: 2909 bp
• RefSeq ORF: 1503 bp
• Locus ID: 7014
• Cytogenetics: 16q22.1
• Domains: myb_DNA-binding
• Protein Families: Transcription Factors
• Gene Summary: 'This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. [provided by RefSeq, Jul 2008]'