RbAp48 (RBBP4) (NM_005610) Human Untagged Clone

CAT#: SC116632

RBBP4 (untagged)-Human retinoblastoma binding protein 4 (RBBP4), transcript variant 1


  "NM_005610" in other vectors (5)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol RBBP4
Synonyms lin-53; NURF55; RBAP48
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_005610, the custom clone sequence may differ by one or more nucleotides


ATGGCCGACAAGGAAGCAGCCTTCGACGACGCAGTGGAAGAACGAGTGATCAACGAGGAATACAAAATAT
GGAAAAAGAACACCCCTTTTCTTTATGATTTGGTGATGACCCATGCTCTGGAGTGGCCCAGCCTAACTGC
CCAGTGGCTTCCAGATGTAACCAGACCAGAAGGGAAAGATTTCAGCATTCATCGACTTGTCCTGGGGACA
CACACATCGGATGAACAAAACCATCTTGTTATAGCCAGTGTGCAGCTCCCTAATGATGATGCTCAGTTTG
ATGCGTCACACTACGACAGTGAGAAAGGAGAATTTGGAGGTTTTGGTTCAGTTAGTGGAAAAATTGAAAT
AGAAATCAAGATCAACCATGAAGGAGAAGTAAACAGGGCCCGTTATATGCCCCAGAACCCTTGTATCATC
GCAACAAAGACTCCTTCCAGTGATGTTCTTGTTTTTGACTATACAAAACATCCTTCTAAACCAGATCCTT
CTGGAGAGTGCAACCCAGACTTGCGTCTCCGTGGACATCAGAAGGAAGGCTATGGGCTTTCTTGGAACCC
AAATCTCAGTGGGCACTTACTTAGTGCTTCAGATGACCATACCATCTGCCTGTGGGACATCAGTGCCGTT
CCAAAGGAGGGAAAAGTGGTAGATGCGAAGACCATCTTTACAGGGCATACGGCAGTAGTAGAAGATGTTT
CCTGGCATCTACTCCATGAGTCTCTGTTTGGGTCAGTTGCTGATGATCAGAAACTTATGATTTGGGATAC
TCGTTCAAACAATACTTCCAAACCAAGCCACTCAGTTGATGCTCACACTGCTGAAGTGAACTGCCTTTCT
TTCAATCCTTATAGTGAGTTCATTCTTGCCACAGGATCAGCTGACAAGACTGTTGCCTTGTGGGATCTGA
GAAATCTGAAACTTAAGTTGCATTCCTTTGAGTCACATAAGGATGAAATATTCCAGGTTCAGTGGTCACC
TCACAATGAGACTATTTTAGCTTCCAGTGGTACTGATCGCAGACTGAATGTCTGGGATTTAAGTAAAATT
GGAGAGGAACAATCCCCAGAAGATGCAGAAGACGGGCCACCAGAGTTGTTGTTTATTCATGGTGGTCATA
CTGCCAAGATATCTGATTTCTCCTGGAATCCCAATGAACCTTGGGTGATTTGTTCTGTATCAGAAGACAA
TATCATGCAAGTGTGGCAAATGGCAGAGAACATTTATAATGATGAAGACCCTGAAGGAAGCGTGGATCCA
GAAGGACAAGGGTCCTAG


>OriGene 5' read for NM_005610 unedited
TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCACAGAGCGAGCTCT
TGCAGCCTCCCCGCCCCTCCCGCAACGCTCGACCCCAGGATTCCCCCGGCTCGCCTGCCC
GCCATGGCCGACAAGGAAGCAGCCTTCGACGACGCAGTGGAAGAACGAGTGATCAACGAG
GAATACAAAATATGGAAAAAGAACACCCCTTTTCTTTATGATTTGGTGATGACCCATGCT
CTGGAGTGGCCCAGCCTAACTGCCCAGTGGCTTCCAGATGTAACCAGACCAGAAGGGAAA
GATTTCAGCATTCATCGACTTGTCCTGGGGACACACACATCGGATGAACAAAACCATCTT
GTTATAGCCAGTGTGCAGCTCCCTAATGATGATGCTCAGTTTGATGCGTCACACTACGAC
AGTGAGAAAGGAGAATTTGGAGGTTTTGGTTCAGTTAGTGGAAAAATTGAAATAGAAATC
AAGATCAACCATGAAGGAGAAGTAAACAGGGCCCGTTATATGCCCCAGAACCCTTGTATC
ATCGCAACAAAGACTCCTTCCAGTGATGTTCTTGTCTTTGACTATACAAAACATCCTTCT
AAACCAGATCCTTCTGGAGAGTGCAACCCAGACTTGCGTCTCCGTGGACATCAGAAGGAA
GGCTATGGGCTTTCTTGGAACCCANATCTCAGTGGGCACTTACTTAGTGCTTCAGATGAC
CATACCATCTGCCTGTGGGACATCAGTGCCCTTCCCAAAGAAGGAAAAGTGGTAGATGCG
AAGACCCATCTTACAGGGCATACGGCAGTAGTAGAAGATGTTCCTGGCATCTACTCCATG
AGTCTCTGTTTGGGCCAGTGCTGATGATCAAAAACTATGATTTGGGATACTCGCTCAAAC
AT
>OriGene 3' read for NM_005610 unedited
TATGAACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTATGTAGAAA
AACAATTTATTCCATTTTAAGCACTTACACAGTTAGTCATGGAGAGTAACAGGCCTGCTG
GTGAAACAGGTCACCCAAAATGGAGATGGCATCAAACTAGTGGTCAAGGACTAACTCCTA
AAAAAAAAAACAACTCTTATCAAGGATTAATTTAATTTTTAAAACAAATACAAGTTATTG
ATTCACTCTTCTCAACTTGACAGTCTACCTGTGGTATAACTGTCAGGTAAAAACATACAT
CTTTACAACTTGGTGGTCCCAAGTTAAAAAAAAAAAAAAAAAAACCAACAACAAAAAAAA
AAACACCATTTCACAGACAGGAAATAAACAACATGAAAACAGCTCAAGAAATACACTAAC
GAGCAAAAATATATGAATATATGGGGAAAGAGGAACGTGTTGTTTTGACTTAACTGAAAA
AACCAAGAGGAAACTGGTCTACGTATGAAAATGTGCATCCTGGAAAGTCAGGTGTCAAGA
TTTTCGAGTAGGAATCTATACGACTTGAATCTCCCCCTATTTCCTGAATAAAAGTGACAT
CTTTCAGTATTTATACTTCATGGCTCAAACACCTACCTCATTTGGCTCTATTCCTTACTC
ACTCTAGCCTTTACTTAAATGAGTCTGAAAAACTTGGGGATATAGCATAAGAAGAAAAAT
AATCACACATAATATTCCCCTTTCTGTAGCTACTTTAGACCTGNGTTACTAGAAAATTCC
TGAAGAAAATTTCAACGTAAGTCTGTGGCTTNTGTGAATCAAGCCCCCCTATAAATTTAG
AAAACACCCACGTTTGGCTATAGCATTATCGTGGTACTATTTATANAGGGAAGCTGATAA
AGN
Restriction Sites ECoRI-NOT     
ACCN NM_005610
Insert Size 2440 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_005610.1, NP_005601.1
RefSeq Size 2314 bp
RefSeq ORF 1278 bp
Locus ID 5928
Cytogenetics 1p35.1
Domains WD40
Protein Families Druggable Genome, Transcription Factors
Gene Summary 'This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]'
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.

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