SAE1 (NM_005500) Human Untagged Clone

CAT#: SC116689

SAE1 (untagged)-Human SUMO1 activating enzyme subunit 1 (SAE1), transcript variant 1


  "NM_005500" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SAE1
Synonyms AOS1; HSPC140; SUA1; UBLE1A
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC116689 sequence for NM_005500 edited (data generated by NextGen Sequencing)
ATGGTGGAGAAGGAGGAGGCTGGCGGCGGCATTAGCGAGGAGGAGGCGGCACAGTATGAC
CGGCAGATCCGCCTGTGGGGACTGGAGGCCCAGAAACGGCTGCGGGCCTCTCGGGTGCTT
CTTGTCGGCTTGAAAGGACTTGGGGCTGAAATTGCCAAGAATCTCATCTTGGCAGGAGTG
AAAGGACTGACCATGCTGGATCACGAACAGGTAACTCCAGAAGATCCCGGAGCTCAGTTC
TTGATTCGTACTGGGTCTGTTGGCCGAAATAGGGCTGAAGCCTCTTTGGAGCGAGCTCAG
AATCTCAACCCCATGGTGGATGTGAAGGTGGACACTGAGGATATAGAGAAGAAACCAGAG
TCATTTTTCACTCAATTCGATGCTGTGTGTCTGACTTGCTGCTCCAGGGATGTCATAGTT
AAAGTTGACCAGATCTGTCACAAAAATAGCATCAAGTTCTTTACAGGAGATGTTTTTGGC
TACCATGGATACACATTTGCCAATCTAGGAGAGCATGAGTTTGTAGAGGAGAAAACTAAA
GTTGCCAAAGTTAGCCAAGGAGTAGAAGATGGGCCCGACACCAAGAGAGCAAAACTTGAT
TCTTCTGAGACAACGATGGTCAAAAAGAAGGTGGTCTTCTGCCCTGTTAAAGAAGCCCTG
GAGGTGGACTGGAGCAGTGAGAAAGCAAAGGCTGCTCTGAAGCGCACGACCTCCGACTAC
TTTCTCCTTCAAGTGCTCTTAAAGTTCCGTACAGATAAAGGAAGAGATCCCAGTTCTGAT
ACATATGAGGAAGATTCTGAGTTGTTGCTCCAGATACGAAATGATGTGCTTGACTCACTG
GGTATTAGTCCTGACCTGCTTCCTGAGGACTTTGTCAGGTACTGCTTCTCCGAGATGGCC
CCAGTGTGTGCGGTGGTTGGAGGGATTTTGGCACAGGAAATTGTGAAGGCCCTGTCTCAG
CGGGACCCTCCTCACAACAACTTCTTCTTCTTCGATGGCATGAAGGGGAATGGGATTGTG
GAGTGCCTTGGCCCCAAGTGA

Clone variation with respect to NM_005500.2
>OriGene 5' read for NM_005500 unedited
AAATTTGGGATTTTGTAATCCGACTTACTATAGGGNCGGACCGCGCAATTCGGCACGAGG
CCGGAGCTGAGGCAGGAAGAGCCGGCGCCATGGTGGAGAAGGAGGAGGCTGGCGGCGGCA
TTAGCGAGGAGGAGGCGGCACAGTATGACCGGCAGATCCGCCTGTGGGGACTGGAGGCCC
AGAAACGGCTGCGGGCCTCTCGGGTGCTTCTTGTCGGCTTGAAAGGACTTGGGGCTGAAA
TTGCCAAGAATCTCATCTTGGCAGGAGTGAAAGGACTGACCATGCTGGATCACGAACAGG
TAACTCCAGAAGATCCCGGAGCTCAGTTCTTGATTCGTACTGGGTCTGTTGGCCGAAATA
GGGCTGAAGCCTCTTTGGAGCGAGCTCAGAATCTCAACCCCATGGTGGATGTGAAGGTGG
ACACTGAGGATATAGAGAAGAAACCAGAGTCATTTTTCACTCAATTCGATGCTGTGTGTC
TGACTTGCTGCTCCAGGGATGTCATAGTTAAAGTTGACCAGATCTGTCACAAAAATAGCA
TCAAGTTCTTTACAGGAGATGTTTTTGGCTACCATGGATACACATTTGCCAATCTAGGAG
AGCATGAGTTTGTAGAGGAGAAAACTAAAGTTGCCAAAGTTAGCCAAGGAGTAGAAGATG
GGCCCGACACCAAGAGAGCAAAACTTGATTCTTCTGAGACAACGATGGTCAAAAAGAAGG
TGGTCTTCTGCCCTGTTAAAGAAGCCCTGNGAGTGGACTGGAGCAGTGAGAAAGCAAGGC
TGCTCTGAAGCGCACGACCTNCGACTACTTTCTCCTTNCAGTGCTCTTAAAGTTCCGTAC
AGATNAAGGAAGAGATCCCAGTTCTGATACATATGAAGAAAGATTCTGAGTGNTGCTNCA
GATACGAATGATGTGC
>OriGene 3' read for NM_005500 unedited
AGAGTCGAGTTTTTTTTTTTTTTTTTTCCTAAAGCAAGTAACTTTATTATCATTCCTTTA
AAAAGAACCAAGGAAAATTCACAACATATGTGAAACACAAACAGCTGTGGTTTAGGAGGT
AAACAAAGGACCAACATAGCCCTGAAATGCAACAGCCTCTGAGTGACTTGAGCCGCATGT
GACTGGGGTTCTGTTAAAAGGGCAGGCTCCTCCCTCCTAGCCCTGAAGCCCCAGGAACCT
GCCTTGAAAGACAAGCTCTCTAATACTCAACTTGCAGGGTCTCGCCCTAACATCCAAGAC
TTGGTAGCATCTCCTTTCTCCCAAAACCCAGCTGGAACTCAACTAATCCTAAACGAAAAC
TCAAGAACAGCACACCAGATGCCACCTGTTGTTTGTCAGGGTCTCAAACTCCAGAGGAAA
TGCATTTGCCTGTCATGGTTTTCCTCTCTAAGGGCACCTGTCTGAACTTGGAGCTGTGCT
TCCACTGGTGCCTCATGGNGCCTGGGCCTACTCTCCACCTGAATTCACACTTTTCTCTAT
AGGTATCAGGTGGGGAATAAGTCCAAGAAGGTGACAAGAGGCTCCCGAGCACAGAGCTTG
CTCATTCCTGNCANGCATCTCCCACAATGCCCCANNAGGGCTGCGAGGCCCGGNACAGCA
TANGGACAGAGAAAGGGCANAGGGGTGCTTGGAAGTGCTCATCACTCANGGGAGCTGCCA
GGCCCCGGATGACANGCANCCTGAACAGTGCTGGAAACAAGACAGNCACCCTGCGCCCCT
TGTCNAGCANCTGCTTNTGATGGGAAANCACACGTCGNCACCACCTTCTTCGTGCANGAA
ATGNTNTGTATCGGGCCCATGACTCAGTTTNCCTTGCTGGAGATGCCTTCATGAAGAAGG
NGACAGGNATACAGNTGGCATGCTGCANTGGCATCTCTGGGCTGCAAAACTTGGNTACTT
GGGGCANGACTNACAATCCATTCCTTATGCTCANAAAAAAAATGTGNAGAGAGGTCGCTA
AAAGGCTNCAATNCTG
Restriction Sites NotI-NotI     
ACCN NM_005500
ORF Size 1041 bp
Insert Size 2050
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_005500.1, NP_005491.1
RefSeq Size 2119
RefSeq ORF 1041
Locus ID 10055
Domains ThiF
Protein Pathways Ubiquitin mediated proteolysis
Gene Summary Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]). [supplied by OMIM, Mar 2010]
Transcript Variant: This variant (1) encodes the longest isoform (a).

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