VEGFC (NM_005429) Human Untagged Clone

CAT#: SC116730

VEGFC (untagged)-Human vascular endothelial growth factor C (VEGFC)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: VEGFC
• Synonyms: Flt4-L; LMPH1D; LMPHM4; VRP
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005429 edited
  GGCACCAGGGGAGAGGGACCAGGAGGGGCCCGCGGCCTCGCAGGGGCGCCCGCGCCCCCA
  CCCCTGCCCCCGCCAGCGGACCGGTCCCCCACCCCCGGTCCTTCCACCATGCACTTGCTG
  GGCTTCTTCTCTGTGGCGTGTTCTCTGCTCGCCGCTGCGCTGCTCCCGGGTCCTCGCGAG
  GCGCCCGCCGCCGCCGCCGCCTTCGAGTCCGGACTCGACCTCTCGGACGCGGAGCCCGAC
  GCGGGCGAGGCCACGGCTTATGCAAGCAAAGATCTGGAGGAGCAGTTACGGTCTGTGTCC
  AGTGTAGATGAACTCATGACTGTACTCTACCCAGAATATTGGAAAATGTACAAGTGTCAG
  CTAAGGAAAGGAGGCTGGCAACATAACAGAGAACAGGCCAACCTCAACTCAAGGACAGAA
  GAGACTATAAAATTTGCTGCAGCACATTATAATACAGAGATCTTGAAAAGTATTGATAAT
  GAGTGGAGAAAGACTCAATGCATGCCACGGGAGGTGTGTATAGATGTGGGGAAGGAGTTT
  GGAGTCGCGACAAACACCTTCTTTAAACCTCCATGTGTGTCCGTCTACAGATGTGGGGGT
  TGCTGCAATAGTGAGGGGCTGCAGTGCATGAACACCAGCACGAGCTACCTCAGCAAGACG
  TTATTTGAAATTACAGTGCCTCTCTCTCAAGGCCCCAAACCAGTAACAATCAGTTTTGCC
  AATCACACTTCCTGCCGATGCATGTCTAAACTGGATGTTTACAGACAAGTTCATTCCATT
  ATTAGACGTTCCCTGCCAGCAACACTACCACAGTGTCAGGCAGCGAACAAGACCTGCCCC
  ACCAATTACATGTGGAATAATCACATCTGCAGATGCCTGGCTCAGGAAGATTTTATGTTT
  TCCTCGGATGCTGGAGATGACTCAACAGATGGATTCCATGACATCTGTGGACCAAACAAG
  GAGCTGGATGAAGAGACCTGTCAGTGTGTCTGCAGAGCGGGGCTTCGGCCTGCCAGCTGT
  GGACCCCACAAAGAACTAGACAGAAACTCATGCCAGTGTGTCTGTAAAAACAAACTCTTC
  CCCAGCCAATGTGGGGCCAACCGAGAATTTGATGAAAACACATGCCAGTGTGTATGTAAA
  AGAACCTGCCCCAGAAATCAACCCCTAAATCCTGGAAAATGTGCCTGTGAATGTACAGAA
  AGTCCACAGAAATGCTTGTTAAAAGGAAAGAAGTTCCACCACCAAACATGCAGCTGTTAC
  AGACGGCCATGTACGAACCGCCAGAAGGCTTGTGAGCCAGGATTTTCATATAGTGAAGAA
  GTGTGTCGTTGTGTCCCTTCATATTGGAAAAGACCACAAATGAGCTAAGATTGTACTGTT
  TTCCAGTTCATCGATTTTCTATTATGGAAAACTGTGTTGCCACAGTAGAACTGTCTGTGA
  ACAGAGAGACCCTTGTGGGTCCATGCTAACAAAGACAAAAGTCTGTCTTTCCTGAACCAT
  GTGGATAACTTTACAGAAATGGACTGGAGCTCATCTGCAAAAGGCCTCTTGTAAAGACTG
  GTTTTCTGCCAATGACCAAACAGCCAAGATTTTCCTCTTGTGATTTCTTTAAAAGAATGA
  CTATATAATTTATTTCCACTAAAAATATTGTTTCTGCATTCATTTTTATAGCAACAACAA
  TTGGTAAAACTCACTGTGATCAATATTTTTATATCATGCAAAATATGTTTAAAATAAAAT
  GAAAATTGTATTAT
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005429 unedited
  GATTTTGGTATACGACTCACTATAGGGCGGCCGCGAATTCGGCACCAGGGGNAAAGGGAC
  CAGGAGGGGCCCGCGGCCTCGCAGGGGCGCCCGCGCCCCCACCCCTGCCCCCGCCAGCGG
  ACCGGTCCCCCACCCCCGGTCCTTCCACCATGCACTTGCTGGGCTTCTTCTCTGTGGCGT
  GTTCTCTGCTCGCCGCTGCGCTGCTCCCGGGTCCTCGCGAGGCGCCCGCCGCCGCCGCCG
  CCTTCGAGTCCGGACTCGACCTCTCGGACGCGGAGCCCGACGCGGGCGAGGCCACGGCTT
  ATGCAAGCAAAGATCTGGAGGAGCAGTTACGGTCTGTGTCCAGTGTAGATGAACTCATGA
  CTGTACTCTACCCAGAATATTGGAAAATGTACAAGTGTCAGCTAAGGAAAGGAGGCTGGC
  AACATAACAGAGAACAGGCCAACCTCAACTCAAGGACAGAAGAGACTATAAAATTTGCTG
  CAGCACATTATAATACAGAGATCTTGAAAAGTATTGATAATGAGTGGAGAAAGACTCAAT
  GCATGCCACGGGAGGTGTGTATAGATGTGGGGAAGGAGTTTGGAGTCGCGACAAACACCT
  TCTTTAAACCTCCATGTGTGTCCGTCTACAGATGTGGNGGTTGCTGCAATAGTGAGGGGC
  TGCAGTGCATGAACACCAGCACGAGCTACCTCAGNCAGACGTTATTTGAAATTACAGTGC
  CTCTCTCTCAGGGCCCANACCAGTANNNCATCAGTTTGCCAATCACACTTCCTGCCGATG
  CATGTCTAACTGGATGNTACAGACAGNTCATTNCATATTAGACCGTCCTGNCAGCACACT
  ACCCAGTGTCAGGCAGCGACAAGACTGCCCCACATTACATGGGATAATACTCTGCCGAGC
  CTGCTCAGAGAATTATTTTTCCTCGAGCTGAGAGACCACAGAGGATCCTGACTCGTGACA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005429
• Insert Size: 1900 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005429.2, NP_005420.1
• RefSeq Size: 2076 bp
• RefSeq ORF: 1260 bp
• Locus ID: 7424
• Cytogenetics: 4q34.3
• Domains: PDGF, CXCXC
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Bladder cancer, Cytokine-cytokine receptor interaction, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma
• Gene Summary: 'The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors. [provided by RefSeq, Apr 2014]'