XRCC2 (NM_005431) Human Untagged Clone

CAT#: SC116732

XRCC2 (untagged)-Human X-ray repair complementing defective repair in Chinese hamster cells 2 (XRCC2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: XRCC2
• Synonyms: FANCU
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116732 sequence for NM_005431 edited (data generated by NextGen Sequencing)
  ATGTGTAGTGCCTTCCATAGGGCTGAGTCTGGGACCGAGCTCCTTGCCCGACTTGAAGGT
  AGAAGTTCCTTGAAAGAAATAGAACCAAATCTGTTTGCTGATGAAGATTCACCTGTGCAT
  GGTGATATTCTTGAATTTCATGGCCCAGAAGGAACAGGAAAAACAGAAATGCTTTATCAC
  CTAACAGCACGATGTATACTTCCCAAATCAGAAGGTGGCCTGGAAGTAGAAGTCTTATTT
  ATTGATACAGATTACCACTTTGATATGCTCCGGCTAGTTACAATTCTTGAGCACAGACTA
  TCCCAAAGCTCTGAAGAAATAATCAAATACTGCCTGGGAAGATTTTTTTTGGTGTACTGC
  AGTAGTAGCACCCACTTACTTCTTACACTTTACTCACTAGAAAGTATGTTTTGTAGTCAC
  CCATCTCTCTGCCTTTTGATTTTGGATAGCCTGTCAGCTTTTTACTGGATAGACCGCGTC
  AATGGAGGAGAAAGTGTGAACTTACAGGAGTCTACTCTGAGGAAATGTTCTCAGTGCTTA
  GAGAAGCTTGTAAATGACTATCGCCTGGTTCTTTTTGCAACGACACAAACTATAATGCAG
  AAAGCCTCGAGCTCATCAGAAGAACCTTCTCATGCCTCTCGACGACTGTGTGATGTGGAC
  ATAGACTACAGACCTTATCTCTGTAAGGCATGGCAGCAACTGGTGAAGCACAGGATGTTT
  TTCTCCAAACAAGATGATTCTCAAAGCAGCAACCAATTTTCATTAGTTTCACGTTGTTTA
  AAAAGTAACAGTTTAAAAAAACATTTTTTTATTATTGGAGAAAGTGGGGTTGAATTTTGT
  TGA
  
  Clone variation with respect to NM_005431.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005431 unedited
  GGAACGTCACATTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGCCTCGT
  GCCGAATTCGGCACGAGGGTAGAGTCTGCGCAGTTGGTGAATGGCGTTGGTGGCGGGAAA
  GTTGAGTCTCTCCTGCGCCGAGCCTTCGGGGCGATGTGTAGTGCCTTCCATAGGGCTGAG
  TCTGGGACCGAGCTCCTTGCCCGACTTGAAGGTAGAAGTTCCTTGAAAGAAATAGAACCA
  AATCTGTTTGCTGATGAAGATTCACCTGTGCATGGTGATATTCTTGAATTTCATGGCCCA
  GAAGGAACAGGAAAAACAGAAATGCTTTATCACCTAACAGCACGATGTATACTTCCCAAA
  TCAGAAGGTGGCCTGGAAGTAGAAGTCTTATTTATTGATACAGATTACCACTTTGATATG
  CTCCGGCTAGTTACAATTCTTGAGCACAGACTATCCCAAAGCTCTGAAGAAATAATCAAA
  TACTGCCTGGGAAGATTTTTTTTGGTGTACTGCAGTAGTAGCACCCACTTACTTCTTACA
  CTTTACTCACTAGAAAGTATGTTTTGTAGTCACCCATCTCTCTGCCTTTTGATTTTGGAT
  AGCCTGTCAGCTTTTTACTGGATAGACCGCGTCAATGGAGGAGAAAGTGTGAACTTACAG
  GAGTCTACTCTGANGAAATGTTCTCAGTGCTTAGAGAAGCTTGTAAATGACTATCGCCTG
  GTTCTTTTTGCAACGACACANACTATNATGCAGAAAGCCTCGAGCTCATCAGAAGNACCT
  TCTCATGCCTCTCGACGACTGTGTGATGTGGACATAGACTACAGACCTTATCTCTGTNAG
  GCATGGCAGCNACTGGNTGAGCACAGGNATGNTTNNTCTCCCAACAGATGATTCTCAAAG
  CAGCACN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005431 unedited
  ATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTATTTTTTATTTT
  TTAGAGATGGAGTCGCCCAGGCGGGAGTGCAATGGCGCGATCTCAGCTCACTGCAACCTC
  CACCTCCTGGGTTCCAGCAATTCTCCTGCCTCGGCCTCCTGAGTAGCTGGCACCACAGGC
  ACGCACCACCATGCCCAGCTAATTTTTTGTATTTTAATAGAGATGGGGTTTCACCGTGTT
  GCCCAGGCTGGTCTTGACCTCCTGAGCGCGGGCAATCCACCCACCTCGGCCTCGCAAAGT
  GCTAGGATCACAGGCATGAGCCACCACGCCCAGTCAGTCTTGTTCCTTTTTATGGCTGTA
  TAGTATTCCCTGGTGTGTATGTACCACATTTTTTTAATCCAGTCTGTCACTGATGGGCAG
  TGCTGCAACGAACATACGCGTGCATGTGTCTTTATAACAATGATTTCTATTCCTTTGGGT
  ATATACCCAGTAATGAGATTGCTGGGTTGAATGGTATCTCTGTCTTTATCCCCACACTGT
  CTTCCACAATGGCTGAACTAATTTAATTTACATTTCCACCAACAGTGTATAAGCATATCT
  TTTTCTCCACAACCTCACCAGCATCTGTTATTTTCTGACATTTTTATAATAGCCATTTGG
  ACTGGTGTGAGATGGTATCTCGTTGTTGTTTCGATTTGCATTTCTCTAATGATCAGTGAT
  GCTGGGCTTTTTTTCATAGGATTGTTGGCCACAGATGTCTTCTTTTGAAAAGTGTCTGTT
  CATGTCCCTTGCCACCTTTTAATGGGGTGGCTTTTTCTTCTAAATTTGTTTAAATACGTA
  TAGGAGCTGGATTTCAGACCTTTCTAGATGCATAGTTGCAACAATTTTCTCCCATCTGGA
  AGCTGCCTGGTTACTCTCCTTGAAATTTCCTTTGCTGGGCGCTCTTTAGTTTAATAAGAC
  CCATTGGGAATTTTTGCTCTGTTGCAATTGTTTTGGCGTCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005431
• Insert Size: 3500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005431.1, NP_005422.1
• RefSeq Size: 3094 bp
• RefSeq ORF: 843 bp
• Locus ID: 7516
• Cytogenetics: 7q36.1
• Protein Families: Druggable Genome
• Protein Pathways: Homologous recombination
• Gene Summary: 'This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. [provided by RefSeq, Jul 2008]'