CCR8 (NM_005201) Human Untagged Clone

CAT#: SC116904

CCR8 (untagged)-Human chemokine (C-C motif) receptor 8 (CCR8)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCR8
• Synonyms: CC-CKR-8; CCR-8; CDw198; CKRL1; CMKBR8; CMKBRL2; CY6; GPRCY6; TER1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005201, RT-PCR generated
  ATGGATTATACACTTGACCTCAGTGTGACAACAGTGACCGACTACTACTACCCTGATATC
  TTCTCAAGCCCCTGTGATGCGGAACTTATTCAGACAAATGGCAAGTTGCTCCTTGCTGTC
  TTTTATTGCCTCCTGTTTGTATTCAGTCTTCTGGGAAACAGCCTGGTCATCCTGGTCCTT
  GTGGTCTGCAAGAAGCTGAGGAGCATCACAGATGTATACCTCTTGAACCTGGCCCTGTCT
  GACCTGCTTTTTGTCTTCTCCTTCCCCTTTCAGACCTACTATCTGCTGGACCAGTGGGTG
  TTTGGGACTGTAATGTGCAAAGTGGTGTCTGGCTTTTATTACATTGGCTTCTACAGCAGC
  ATGTTTTTCATCACCCTCATGAGTGTGGACAGGTACCTGGCTGTTGTCCATGCCGTGTAT
  GCCCTAAAGGTGAGGACGATCAGGATGGGCACAACGCTGTGCCTGGCAGTATGGCTAACC
  GCCATTATGGCTACCATCCCATTGCTAGTGTTTTACCAAGTGGCCTCTGAAGATGGTGTT
  CTACAGTGTTATTCATTTTACAATCAACAGACTTTGAAGTGGAAGATCTTCACCAACTTC
  AAAATGAACATTTTAGGCTTGTTGATCCCATTCACCATCTTTATGTTCTGCTACATTAAA
  ATCCTGCACCAGCTGAAGAGGTGTCAAAACCACAACAAGACCAAGGCCATCAGGTTGGTG
  CTCATTGTGGTCATTGCATCTTTACTTTTCTGGGTCCCATTCAACGTGGTTCTTTTCCTC
  ACTTCCTTGCACAGTATGCACATCTTGGATGGATGTAGCATAAGCCAACAGCTGACTTAT
  GCCACCCATGTCACAGAAATCATTTCCTTTACTCACTGCTGTGTGAACCCTGTTATCTAT
  GCTTTTGTTGGGGAGAAGTTCAAGAAACACCTCTCAGAAATATTTCAGAAAAGTTGCAGC
  CAAATCTTCAACTACCTAGGAAGACAAATGCCTAGGGAGAGCTGTGAAAAGTCATCATCC
  TGCCAGCAGCACTCCTCCCGTTCCTCCAGCGTAGACTACATTTTGTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005201 unedited
  CTTCCCTCGTTTTGTTTCCAGACTAGGGGANGGCGGCACACCCTGTGATGTGAATCTGCA
  GAATTCGGCTTATGGATTATACACTTGACCTCAGTGTGACAACAGTGACCGACTACTACT
  ACCCTGATATCTTCTCAAGCCCCTGTGATGCGGAACTTATTCAGACAAATGGCAAGTTGC
  TCCTTGCTGTCTTTTATTGCCTCCTGTTTGTATTCAGTCTTCTGGGAAACAGCCTGGTCA
  TCCTGGTCCTTGTGGTCTGCAAGAAGCTGAGGAGCATCACAGATGTATACCTCTTGAACC
  TGGCCCTGTCTGACCTGCTTTTTGTCTTCTCCTTCCCCTTTCAGACCTACTATCTGCTGG
  ACCAGTGGGTGTTTGGGACTGTAATGTGCAAAGTGGTGTCTGGCTTTTATTACATTGGCT
  TCTACAGCAGCATGTTTTTCATCACCCTCATGAGTGTGGACAGGTACCTGGCTGTTGTCC
  ATGCCGTGTATGCCCTAAAGGTGAGGACGATCAGGATGGGCACAACGCTGTGCCTGGCAG
  TATGGCTAACCGCCATTATGGCTACCATCCCATTGCTAGTGTTTTACCAAGTGGCCTCTG
  AAGATGGTGTTCTACAGTGTTATTCATTTTACAATCAACAGACTTTGAAGTGGAAGATCT
  TCACCAACTTCAAAATGAACATTTTAGGCTTGTTGATCCCATTCACCATCTTTATGTTCT
  GCTACATTAAAATCCTGCACCAGCTGAAGAGGTGTCAAAACCACAACAAGACCCAAGCCA
  TCAGGTTGNGTGCTACATGTGGTCATTGCATNCTTACTTTTCTGGGTCCCATTCAACGTG
  GTTCTTTTCTCACTTCCTTGCACAGTATGCACATCTTTGGATGGATGTAGCATAAGCAAC
  AGCTGACTTATGCCCCCATGTCA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005201 unedited
  NNNNAAAATAACTGTGNACCGCGGCCCGCTTNCTAGNGATCGAAANCTTGATATCGGTAC
  CGAGCTCGGNATCCCTAGTAACGGCCGCCAGTGTGCTGGAATTCGGCTTAGTCTTCATTG
  ATCCTCACAAAATGTAGTCTACGCTGGAGGAACGGGAGGAGTGCTGCTGGCAGGATGATG
  ACTTTTCACAGCTCTCCCTAGGCATTTGTCTTCCTAGGTAGTTGAAGATTTGGCTGCAAC
  TTTTCTGAAATATTTCTGAGAGGTGTTTCTTGAACTTCTCCCCAACAAAAGCATAGATAA
  CAGGGTTCACACAGCAGTGAGTAAAGGAAATGATTTCTGTGACATGGGTGGCATAAGTCA
  GCTGTTGGCTTATGCTACATCCATCCAAGATGTGCATACTGTGCAAGGAAGTGAGGAAAA
  GAACCACGTTGAATGGGACCCAGAAAAGTAAAGATGCAATGACCACAATGAGCACCAACC
  TGATGGCCTTGGTCTTGTTGTGGTTTTGACACCTCTTCAGCTGGTGCAGGATTTTAATGT
  AGCAGAACATAAAGATGGTGAATGGGATCAACAAGCCTAAAATGTTCATTTTGAAGTTGG
  TGAAGATCTTCCACTTCAAAGTCTGTTGATTGTAAAATGAATAACACTGTAGAACACCAT
  CTTCAGAGGCCACTTGGTAAAACACTAGCAATGGGATGGTAGCCATAATGGCGGTTAGCC
  ATACTGCCAGGCACAGCGTTGTGCCCATCCTGATCGTCCTCACCTTTAGGGCATACACGG
  CATGGACAACAGCCAGGTACCTGTCCACAACTCATGAAGGTGATGAAAAACATGCCGCTG
  GTAAAACCCCAGGTATAAAGACCCAGACACCCTTTTGCCCTTTACAGTTCCCAAAACCCA
  CTGG
  
• Restriction Sites: Please inquire
• ACCN: NM_005201
• Insert Size: 1300 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005201.2, NP_005192.1
• RefSeq Size: 2370 bp
• RefSeq ORF: 1068 bp
• Locus ID: 1237
• Cytogenetics: 3p22.1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction
• Gene Summary: 'This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]'