Y14 (RBM8A) (NM_005105) Human Untagged Clone

CAT#: SC116929

RBM8A (untagged)-Human RNA binding motif protein 8A (RBM8A)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RBM8A
• Synonyms: BOV-1A; BOV-1B; BOV-1C; C1DELq21.1; DEL1q21.1; MDS014; RBM8; RBM8B; TAR; Y14; ZNRP; ZRNP1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_005105, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGACGTGCTAGATCTTCACGAGGCTGGGGGCGAAGATTTCGCCATGGATGAGGATGGGGACGAGA
  GCATTCACAAACTGAAAGAAAAAGCGAAGAAACGGAAGGGTCGCGGCTTTGGCTCCGAAGAGGGGTCCCG
  AGCGCGGATGCGTGAGGATTATGACAGCGTGGAGCAGGATGGCGATGAACCCGGACCACAACGCTCTGTT
  GAAGGCTGGATTCTCTTTGTAACTGGAGTCCATGAGGAAGCCACCGAAGAAGACATACACGACAAATTCG
  CAGAATATGGGGAAATTAAAAACATTCATCTCAACCTCGACAGGCGAACAGGATATCTGAAGGGGTATAC
  TCTAGTTGAATATGAAACATACAAGGAAGCCCAGGCTGCTATGGAGGGACTCAATGGCCAGGATTTGATG
  GGACAGCCCATCAGCGTTGACTGGTGTTTTGTTCGGGGTCCACCAAAAGGCAAGAGGAGAGGTGGCCGAA
  GACGCAGCAGAAGTCCAGACCGGAGACGTCGCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005105 unedited
  NGGTTCANAATTTGTAATACGACTTACTATAGGGCGGCCGCGAAATTCGCACGAGGGCGA
  GATGGCGGACGTGCTAGATCTTCACGAGGCTGGGGGCGAAGATTTCGCCATGGATGAGGA
  TGGGGACGAGAGCATTCACAAACTGAAAGAAAAAGCGAAGAAACGGAAGGGTCGCGGCTT
  TGGCTCCGAAGAGGGGTCCCGAGCGCGGATGCGTGAGGATTATGACAGCGTGGAGCAGGA
  TGGCGATGAACCCGGACCACAACGCTCTGTTGAAGGCTGGATTCTCTTTGTAACTGGAGT
  CCATGAGGAAGCCACCGAAGAAGACATACACGACAAATTCGCAGAATATGGGGAAATTAA
  AAACATTCATCTCAACCTCGACAGGCGAACAGGATATCTGAAGGGGTATACTCTAGTTGA
  ATATGAAACATACAAGGAAGCCCAGGCTGCTATGGAGGGACTCAATGGCCAGGATTTGAT
  GGGACAGCCCATCAGCGTTGACTGGTGTTTTGTTCGGGGTCCACCAAAAGGCAAGAGGAG
  AGGTGGCCGAAGACGCAGCAGAAGTCCAGACCGGAGACGTCGCTGACAGGTCCTCTGTTG
  TCCAGGTGTTCTCTTCAAGATTCCATTTGACCATGCAGCCTTGGACAAATAGGACTGNGG
  TGGAACTTGCTGTGTTTATATTTAATCTCTTACCGTATATGCGTAGTATTTGAGTTGCGA
  ATAAATGTTCCATTTTTGTTNTCTACATTTAATGTTACTTTCCTGTCCTAAAATGAAAAG
  TCTAAAGCATAGCAGGNCTGTATGGATCATTGTGAAGATACTTCTAGGNACTGAACTCTA
  TGNATTNCTTTNTTTTTCTTNTTNTGAGAAGAGTCTTGCTGTGTTACCCANGNNTGNATG
  CAGCTGATATAGCTACTGCAGCTTCAACTCTGGGCTCAAGCATNCTCTGNCTACTGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005105 unedited
  NNTTTTAGCTTTGNACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGG
  CATTTGGAAAATGTTAAATTTTATTATTTAACATTCTTTACCATTATAGTTACTGCACAT
  AAGACTATTACTACTAAAGGTCACTTCAGAGTCCCTGCAAAATGGCCTGGAATTTTGGCA
  GCACCCATTTTACACAATATTTCTTTTTCCACAAAATAACAGACATACCAGGAAAATCAT
  TTCAGCTAAAAATATGAGTGAGGTGGTAGAAATATCATCCCTTATAAAGCGCAATGTTAG
  AATAGTACTTGAGAAAGCAGGATTGTTTTAAGTTCCAAGATTTAACAAACTTACTGTTCA
  GCATCATATTCAAGCCTAAAAGGAAGATAGGATTTTCAAGATATATTTCCAACTTCTTTA
  ACATGGCACCATGGATGAACTGTTTCTCAGCACTGTGCTGCTTCACTTGGAATTAAGGAT
  GAATTGGGAGGAGACAGTATGACATAGGTGGGTAGGTTGGGTGGTGAGGGGAACCAGTTC
  TAATAGTCCTCAACTCCACTCCAGCTGTTCCTGTTCCACACGGTCCACTGAGCTGGCCCA
  GTCCCTTTCACTCAGTGTGTCACCAAAGGCAGCTTCAAGGCTCAATGGCAAGAGACCACC
  TATAACCTCTTCACCTTCTGCTGCCTCTTTCTGCTGCCACTGACTGCCATGGCCATCTGC
  TATAGCCGCATTGTCCTCAGTGTGTCCAGGCCCCAGACAGGNAAGGNGAGCCATGGTGAG
  ACTNCAATTCCCAGCCCTAATCCTTAAAACCTAGACTGTGNCTCTAGCATCATTTANTTA
  TCTACCTACCCTATAGCTATCTACCAGTCACTAAACCATGGTGAGAATCTACCATGTCTA
  GCACCTGAGCTAGAGATAATTTTGNTGAATCCCTTCCATATAACAGCTGAGGTAGCTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005105
• ORF Size: 525 bp
• Insert Size: 2880
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_005105.2, NP_005096.1
• RefSeq Size: 2787
• RefSeq ORF: 525
• Locus ID: 9939
• Domains: RRM
• Protein Families: Druggable Genome
• Protein Pathways: Spliceosome
• Gene Summary: This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013]