MVP (NM_005115) Human Untagged Clone

CAT#: SC116936

MVP (untagged)-Human major vault protein (MVP), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MVP
• Synonyms: LRP; VAULT1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005115 edited
  GAATTCGGCACGAGGGTTTGTTGCAGCTACCTGCACTTCTAGATCCCTGGGCTTAGGAGT
  CACCATGGCAACTGAAGAGTTCATCATCCGCATCCCCCCATACCACTATATCCATGTGCT
  GGACCAGAACAGCAACGTGTCCCGTGTGGAGGTCGGGCCAAAGACCTACATCCGGCAGGA
  CAATGAGAGGGTACTGTTTGCCCCCATGCGCATGGTGACCGTCCCCCCACGTCACTACTG
  CACAGTGGCCAACCCTGTGTCTCGGGATGCCCAGGGCTTGGTGCTGTTTGATGTCACAGG
  GCAAGTTCGGCTTCGCCACGCTGACCTCGAGATCCGGCTGGCCCAGGACCCCTTCCCCCT
  GTACCCAGGGGAGGTGCTGGAAAAGGACATCACACCCCTGCAGGTGGTTCTGCCCAACAC
  TGCCCTCCATCTAAAGGCGCTGCTTGATTTTGAGGATAAAGATGGAGACAAGGTGGTGGC
  AGGAGATGAGTGGCTTTTCGAGGGACCTGGCACGTACATCCCCCGGAAGGAAGTGGAGGT
  CGTGGAGATCATTCAGGCCACCATCATCAGGCAGAACCAGGCTCTGCGGCTCAGGGCCCG
  CAAGGAGTGCTGGGACCGGGACGGCAAGGAGAGGGTGACAGGGGAAGAATGGCTGGTCAC
  CACAGTAGGGGCGTACCTCCCAGCGGTGTTTGAGGAGGTTCTGGATTTGGTGGACGCCGT
  CATCCTTACGGAAAAGACAGCCCTGCACCTCCGGGCTCGGCGGAACTTCCGGGACTTCAG
  GGGAGTGTCCCGCCGCACTGGGGAGGAGTGGCTGGTAACAGTGCAGGACACAGAGGCCCA
  CGTGCCAGATGTCCACGAGGAGGTGCTGGGGGTTGTGCCCATCACCACCCTGGGCCCCCA
  CAACTACTGCGTGATTCTCGACCCTGTCGGACCGGATGGCAAGAATCAGCTGGGGCAGAA
  GCGCGTGGTCAAGGGAGAGAAGTCTTTTTTCCTCCAGCCAGGAGAGCAGCTGGAACAAGG
  CATCCAGGATGTGTATGTGCTGTCGGAGCAGCAGGGGCTGCTGCTGAGGGCCCTGCAGCC
  CCTGGAGGAGGGGGAGGATGAGGAGAAGGTCTCACACCAGGCTGGGGACCACTGGCTCAT
  CCGCGGACCCCTGGAGTATGTGCCATCTGCCAAAGTGGAGGTGGTGGAGGAGCGCCAGGC
  CATCCCTCTAGACGAGAACGAGGGCATCTATGTGCAGGATGTCAAGACCGGAAAGGTGCG
  CGCTGTGATTGGAAGCACCTACATGCTGACCCAGGACGAAGTCCTGTGGGAGAAAGAGCT
  GCCTCCCGGGGTGGAGGAGCTGCTGAACAAGGGGCAGGACCCTCTGGCAGACAGGGGTGA
  GAAGGACACAGCTAAGAGCCTCCAGCCCTTGGCGCCCCGGAACAAGACCCGTGTGGTCAG
  CTACCGCGTGCCCCACAACGCTGCGGTGCAGGTGTACGACTACCGAGAGAAGCGAGCCCG
  CGTGGTCTTCGGGCCTGAGCTGGTGTCGCTGGGTCCTGAGGAGCAGTTCACAGTGTTGTC
  CCTCTCAGCTGGGCGGCCCAAGCGTCCCCATGCCCGCCGTGCGCTCTGCCTGCTGCTGGG
  GCCTGACTTCTTCACAGACGTCATCACCATCGAAACGGCGGATCATGCCAGGCTGCAACT
  GCAGCTGGCCTACAACTGGCACTTTGAGGTGAATGACCGGAAGGACCCCCAAGAGACGGC
  CAAGCTCTTTTCAGTGCCAGACTTTGTAGGTGATGCCTGCAAAGCCATCGCATCCCGGGT
  GCGGGGGGCCGTGGCCTCTGTCACTTTCGATGACTTCCATAAGAACTCAGCCCGCATCAT
  TCGCACTGCTGTCTTTGGCTTTGAGACCTCGGAAGCGAAGGGCCCCGATGGCATGGCCCT
  GCCCAGGCCCCGGGACCAGGCTGTCTTCCCCCAAAACGGGCTGGTGGTCAGCAGTGTGGA
  CGTGCAGTCAGTGGAGCCTGTGGATCAGAGGACCCGGGACGCCCTGCAACGCAGCGTCCA
  GCTGGCCATCGAGATCACCACCAACTCCCAGGAAGCGGCGGCCAAGCATGAGGCTCAGAG
  ACTGGAGCAGGAAGCCCGCGGCCGGCTTGAGCGGCAGAAGATCCTGGACCAGTCAGAAGC
  CGAGAAAGCTCGCAAGGAACTTTTGGAGCTGGAGGCTCTGAGCATGGCCGTGGAGAGCAC
  CGGGACTGCCAAGGCGGAGGCCGAGTCCCGTGCGGAGGCAGCCCGGATTGAGGGAGAAGG
  GTCCGTGCTGCAGGCCAAGCTAAAAGCACAGGCCTTGGCCATTGAAACGGAGGCTGAGCT
  CCAGAGGGTCCAGAAGGTCCGAGAGCTGGAACTGGTCTATGCCCGGGCCCAGCTGGAGCT
  GGAGGTGAGCAAGGCTCAGCAGCTGGCTGAGGTGGAGGTGAAGAAGTTCAAGCAGATGAC
  AGAGGCCATAGGCCCCAGCACCATCAGGGACCTTGCTGTGGCTGGGCCTGAGATGCAGGT
  AAAACTGCTCCAGTCCCTGGGCCTGAAATCAACCCTCATCACCGATGGCTCCACTCCCAT
  CAACCTCTTCAACACAGCCTTTGGGCTGCTGGGGATGGGGCCCGAGGGTCAGCCCCTGGG
  CAGAAGGGTGGCCAGTGGGCCCAGCCCTGGGGAGGGGATATCCCCCCAGTCTGCTCAGGC
  CCCTCAAGCTCCTGGAGACAACCACGTGGTGCCTGTACTGCGCTAACTCCTGATTAATAC
  AATGGAAGTTTCTGGGCATTTACAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005115 unedited
  CAGATTTGTATACGACTCATATAGGCGGCNCGCGAATTCGCACAGGGGTTTGTTGCAGCT
  ACCTGCACTTCTAGATCCCTGGGCTTAGGAGTCACCATGGCAACTGAAGAGTTCATCATC
  CGCATCCCCCCATACCACTATATCCATGTGCTGGACCAGAACAGCAACGTGTCCCGTGTG
  GAGGTCGGGCCAAAGACCTACATCCGGCAGGACAATGAGAGGGTACTGTTTGCCCCCATG
  CGCATGGTGACCGTCCCCCCACGTCACTACTGCACAGTGGCCAACCCTGTGTCTCGGGAT
  GCCCAGGGCTTGGTGCTGTTTGATGTCACAGGGCAAGTTCGGCTTCGCCACGCTGACCTC
  GAGATCCGGCTGGCCCAGGACCCCTTCCCCCTGTACCCAGGGGAGGTGCTGGAAAAGGAC
  ATCACACCCCTGCAGGTGGTTCTGCCCAACACTGCCCTCCATCTAAAGGCGCTGCTTGAT
  TTTGAGGATAAAGATGGAGACAAGGTGGTGGCAGGAGATGAGTGGCTTTTCGAGGGACCT
  GGCACGTACATCCCCCGGAAGGAAGTGGAGGTCGTGGAGATCATTCAGGCCACCATCATC
  AGGCAGAACCAGGCTCTGCGGCTCAGGGCCCGCAAGGAGTGCTGGGACCGGGACGGCAAG
  GAGAGGGTGACAGGGGAAGAATGGCTGGTCACCACAGTAGGGGCGTACCTCCCAGCGGTG
  TTTGAGGAGGNTCTGGATTTGGTGGACGCCGTCATCCTTACGGAAAAGAAGCCCTGCACC
  TCCGGGCTCGGCGGAACTTCCGGGACTTCAGGGGAGTGTCCCGCCGCACTGGNGNAGAGT
  GGGCTGGTACAGTGCANGACACAGAAGGCCACGTGCCANAAGTNCACAAGGAGTGCTGGG
  GGGGTTGTTGCCATTACCACCCTGGGCCCCNACAACTACTGCGTGAATCTCGACCCTGTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005115 unedited
  GCCGCACTCTAAAGTCGAGTTTTTTTTTTTTTTTTTTGTAAATGCCCAAAAACTTCCATT
  GTATTAATCAGGAGTTAGCGCAGTACAGGCACCACGTGGTTGTCTCCAGGAGCTTGAGGG
  GCCTGAGCAGACTGGGGGGATATCCCCTCCCCAGGGCTGGGCCCACTGGCCACCCTTCTG
  CCCAGGGGCTGACCCTCGGGCCCCATCCCCAGCAGCCCAAAGGCTGTGTTGAAGAGGTTG
  ATGGGAGTGGAGCCATCGGTGATGAGGGTTGATTTCAGGCCCAGGGACTGGAGCAGTTTT
  ACCTGCATCTCAGGCCCAGCCACAGCAAGGTCCCTGATGGTGCTGGGGCCTATGGCCTCT
  GTCATCTGCTTGAACTTCTTCACCTCCACCTCAGCCAGCTGCTGAGCCTTGCTCACCTCC
  AGCTCCAGCTGGGCCCGGGCATAGACCAGTTCCAGCTCTCGGACCTTCTGGACCCTCTGG
  AGCTCAGCCTCCGTTTCAATGGCCAAGGCCTGTGCTTTTAGCTTGGCCTGCAGCACGGAC
  CCTTCTCCCTCAATCCGGGCTGCCTCCGCACGGGACTCGGCCTCCGCCTTGGCAGTTCCG
  GTGCTCTCCACGGCCATGCTCAGAGCCTCCAGCTCCAAAAGTTCCTTGCGAGCCTTTCTC
  GGTTCTGACCGGGCCAGGATCCTCTGCCGCTCAAGCCGGCCCGGGGGCTCTCTGCTCCAG
  TCTCCTGACCCCAATGCTTGGCCGCCGCCTCCTGGGAGTTGTCGGGGATCCCCATGGCCA
  ACTTGAACCCTGGGTTCAAGGGCGTCCCGGGTCCTCTTGATACAAAGCTCCACTGACTGC
  ACGTCCCACTGCTGGACCCAACCCGTTTGGTGGAATTACGCCTGTCCCAGGCTCGGGCAG
  GGCCTTCCTCGGGGCCCTTCCTTCCCAGGCTAAAAGCACAACGAATGCAAGGAGCGGCCT
  GGTCTCTTGGAAACACCCAAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005115
• ORF Size: 2682 bp
• Insert Size: 2740
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_005115.3, NP_005106.2
• RefSeq Size: 2821
• RefSeq ORF: 2682
• Locus ID: 9961
• Domains: Vault
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
  Transcript Variant: This variant (2, also known as S-MVP) uses a different splice site in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same isoform 1.