RAB7 (RAB7A) (NM_004637) Human Untagged Clone

CAT#: SC117240

RAB7A (untagged)-Human RAB7A, member RAS oncogene family (RAB7A)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RAB7A
• Synonyms: PRO2706; RAB7
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117240 sequence for NM_004637 edited (data generated by NextGen Sequencing)
  ATGACCTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGG
  AAGACATCACTCATGAACCAGTATGTGAATAAGAAATTCAGCAATCAGTACAAAGCCACA
  ATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAG
  ATATGGGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGT
  GCAGACTGCTGCGTTCTGGTATTTGATGTGACTGCCCCCAACACATTCAAAACCCTAGAT
  AGCTGGAGAGATGAGTTTCTCATCCAGGCCAGTCCCCGAGATCCTGAAAACTTCCCATTT
  GTTGTGTTGGGAAACAAGATTGACCTCGAAAACAGACAAGTGGCCACAAAGCGGGCACAG
  GCCTGGTGCTACAGCAAAAACAACATTCCCTACTTTGAGACCAGTGCCAAGGAGGCCATC
  AACGTGGAGCAGGCGTTCCAGACGATTGCACGGAATGCACTTAAGCAGGAAACGGAGGTG
  GAGCTGTACAACGAATTTCCTGAACCTATCAAACTGGACAAGAATGACCGGGCCAAGGCC
  TCGGCAGAAAGCTGCAGTTGCTGA
  
  Clone variation with respect to NM_004637.5
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004637 unedited
  TGTATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTCGTGCC
  GAATTCGGCACGAGGATAAAGCCTGAGGCGGCGGCAGCGGCGGAGTTGGCGGCTTGGAGA
  GCTCGGGAGAGTTCCCTGGAACCAGAACTTGGACCTTCTCGCTTCTGTCCTCCGTTTAGT
  CTCCTCCTCGGCGGGAGCCCTCGCGACGCGCCCGGCCCGGAGCCCCCAGCGCAGCGGCCG
  CGTTTGAAGGATGACCTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTC
  TGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAATAAGAAATTCAGCAATCAGTA
  CAAAGCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGT
  CACAATGCAGATATGGGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTT
  CTACAGAGGTGCAGACTGCTGCGTTCTGGTATTTGATGTGACTGCCCCCAACACATTCAA
  AACCCTAGATAGCTGGAGAGATGAGTTTCTCATCCAGGCCAGTCCCCGAGATCCTGAAAA
  CTTCCCATTTGTTGTGTCTGGGAAACAAGATCGACCCTCGAAACCAGACAGTGGCCACAA
  AAGCGGCACAGGCCTGTTGCTACAGCAAAAACCACATTCCCTACTTTGAGACCAGTGCCA
  CAGAAGCCATCCACGTGGAGCAGGCGTTCCAGACGATTGCACGGAATGCACCTTAGCATG
  AAACGGAGGTGGAGCTGTACACCGAATTTCCTGACCTATCAACTGGACAAGAATGCCCGG
  GCCAAGGCTCNGCANAAAGCTGCACTTGCTGAGGGGCCTTGAGAGTTGACCCAGATCCTT
  TCAAACCAGGACCACGTAAGCGCTCAACCAATTCCCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004637 unedited
  TGACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTAACAAGGGTCTTGGTCAATTTTATTGGCATTGGG
  TTCATTTTTTTACAAAAAAACTCACCCCACCCCCTAAAATGTAAACCTTTGGAAAAAGGA
  AAAGTGCTCCGTTAAACAAGCTACAATGCAGGGGCGAAATTCTCTAGGAAGGGAGCAAAA
  CTGCCAGGGTTCCAACCAAAGAAAGAGGTTAATTAATAATGGGCAATATTGGGGAAATGG
  GTGGGGAAAANAGAAAAAGCTCCGCTAACCTAAGAAACCACAACCCTGAAAGGAGCGCCT
  TCTAGAACAAAGGTAAAATCACTAGGACAGATCTGTTAAGGTTTTCCTTTCACTCTTGTA
  NAAAATGCTGATCTAACGGGAGTTTTGAGTGTGGGGCAGGGGGGAAAAAAAAGAAAGAAA
  TGAGAATTTAATTTTTGAAATACGGGATTTATCCATCGACATACCACTGTATATGCAAAT
  CACGTTTTGGAAAATTANACACGGAAGGGACCTGACGTTTTCCCCTGAAAAATGAAAAGC
  TTTTTGCTCTTAGTCTTTGATAAAGGCGACATAATCTTGGGTTACTGACAGAATACTGCC
  GCTACCGGGATTTCCAATCTGAGTACACCTTGAATCCAACAGGGTTAACCCTCCCCTTAA
  GGGCTGTTTTCAGGACTAAAACCTTATCAAGAATTTTTACCTAATTAACATTTTATTGGG
  GCTTTTTTGCATGTCCTAAAAACTTTTCTAAAAACTTCCTTATAAAGGGTCTGAAAAAGA
  CTTGTTTTTAAAGTACACCCTTACGATGATCTCCAAATCNCCTGAAAATGGGGTAACCTT
  ATGGGCTGGGCCCACACTCCAGGGGTCCCTTAGGGGGGGGAAGGGGGGANACACCCNGAC
  TTAAAATCCGTTTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004637
• ORF Size: 624 bp
• Insert Size: 2100
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_004637.5, NP_004628.4
• RefSeq Size: 2240
• RefSeq ORF: 624
• Locus ID: 7879
• Protein Families: Druggable Genome
• Gene Summary: RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]