CDK2AP1 (NM_004642) Human Untagged Clone

CAT#: SC117244

CDK2AP1 (untagged)-Human cyclin-dependent kinase 2 associated protein 1 (CDK2AP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDK2AP1
• Synonyms: doc-1; DOC1; DORC1; p12DOC-1; ST19
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117244 sequence for NM_004642 edited (data generated by NextGen Sequencing)
  ATGTCTTACAAACCGAACTTGGCCGCGCACATGCCCGCCGCCGCCCTCAACGCCGCTGGG
  AGTGTCCACTCGCCTTCCACCAGCATGGCAACGTCTTCACAGTACCGCCAGCTGCTCAGT
  GACTACGGGCCACCGTCCCTAGGCTACACCCAGGGAACTGGGAACAGCCAGGTGCCCCAA
  AGCAAATACGCGGAGCTGCTGGCCATCATTGAAGAGCTGGGGAAGGAGATCAGACCCACG
  TACGCAGGGAGCAAGAGTGCCATGGAGAGGCTGAAGCGCGGCATCATTCACGCTAGAGGA
  CTGGTTCGGGAGTGCTTGGCAGAAACGGAACGGAATGCCAGATCCTAG
  
  Clone variation with respect to NM_004642.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004642 unedited
  GGTTCAAAATTGTAAACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGCCTCGTGCC
  GAATTCGGCACGAGGGCCGCCCGGGGGGATGTCTTACAAACCGAACTTGGCCGCGCACAT
  GCCCGCCGCCGCCCTCAACGCCGCTGGGAGTGTCCACTCGCCTTCCACCAGCATGGCAAC
  GTCTTCACAGTACCGCCAGCTGCTCAGTGACTACGGGCCACCGTCCCTAGGCTACACCCA
  GGGAACTGGGAACAGCCAGGTGCCCCAAAGCAAATACGCGGAGCTGCTGGCCATCATTGA
  AGAGCTGGGGAAGGAGATCAGACCCACGTACGCAGGGAGCAAGAGTGCCATGGAGAGGCT
  GAAGCGCGGCATCATTCACGCTAGAGGACTGGTTCGGGAGTGCTTGGCAGAAACGGAACG
  GAATGCCAGATCCTAGCTGCCTTGTTGGTTTTGAAGGATTTCCATCTTTTTACAAGATGA
  GAAGTTACAGTTCATCTCCCCTGTTCAGATGAAACCCTTGTTTTCAAAATGGTTACAGTT
  TCGTTTTTCCTCCCATGGTTCACTTGGCTCTGAACCTACAGTCTCAAAGATTGAGAAAAG
  ATTTTGCAGTTAATTAGGATTTGCATTTTAAGTAGTTAGGAACTGCCCNAGTTTTTTTTG
  TTTTTTAAGCATTGATTTAAAAGATGCACGGGAAAGTATCTTACAGCANACTGTAGTTTG
  CCTCCAAGACACCCATGTCTCCCCTTAAAATCTCTCTTTGGATACATTTTGTACCCATGG
  GGTGTCTTGNTCCNTTTCATAGCTAATACACTGTAGGGTNATTTGTTTTGACGCATATTG
  ACAGCACGCTTTACTTAGTAGCCGGTTCCCATTTGCCATACAATGTAAGGNTCTGCTAAT
  GTACTNCTTTTTTGGCTAAGCATTGCATGACTATTAATGGCTTCAAGTCAATTTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004642 unedited
  NNNNNAAAANNNNNTTTTCTTTAGGANCGCGGNNCCGCATTCTANNGATCGGTTTTTTTT
  TTTTTTTTTTTTTTTAATAAAAATAAGCTTTATTACATCAAGTAATAAATACATACAAAG
  ATGCAAACAGTTTTAGTCATTTTCTTCCAGATGTTTTTATCAACTTACAATAAACGCAGA
  ACTGAGATCTACTTACAGTCTTAGTATGAAAGTGTTCGGGGGTCCTTGTTAGGTTTGGTG
  GGTTGCTCTTTCTTCTGTATTTATAACTTGTGCATTTTTAAAAATTGACTTTGAAGCACT
  AATAGTCATGCAAATGCTTAAGCAAAAAAGAAGTACATTAAGCAGAACCTACATTGTATG
  GCAAATGGGAACCCGCTACTAAGTAAAGCGTGCTGTCAATATGCGTTCAAAACAAAATCC
  CTACAGTGGTATTTAGCTTATGAAAGGGACAAAGANCACCNTGGGTAACAAATGTTTTCC
  AAAAGAGAAGATAAAGGGAGACCATGTTGTCTTGGAGCAAACTACCGTTTGCTGTAAAAT
  AACTTTCCGGGCATCTTTTAAATCAATGCTTAAAAAACAAAAAAACCTGGGCAAGTCCCT
  ACTTACTAAATGGCAATCCTAATATACCGCAAAACTTTTTTAATCTTTTAACTTGAGGGT
  CAAAGCCAGTAACCTTGGGAGGAAAAACAAACTGTGACCCTTTGAAAACAAGGTTTATTT
  TAACGGGGGAAAGAACTGGACCTCTTATTTGGAAAAGAGGGAACCTTTAAAACCCCAGGG
  CGTAGGATTGGGGTTCCGTCCCTTTTTGGGAAACCTCCCCACAAGCCTTTTAGGGAAAGG
  CCCCGGTTAACCTCTCAGGGGCTTGGCCCCGTGGACGGGGGGTAATCCTTTCCCCTTTTA
  AAAGGGGCCCCCTCCCTTTTTTTTTTGGGCCCGGGGGTCCCCACCTGGGGGAACCGGGAG
  GGGGGCCCTAATTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004642
• ORF Size: 348 bp
• Insert Size: 1180
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_004642.2, NP_004633.1
• RefSeq Size: 1627
• RefSeq ORF: 348
• Locus ID: 8099
• Gene Summary: The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer protein (isoform 1).