RABGGTB (NM_004582) Human Untagged Clone

CAT#: SC117291

RABGGTB (untagged)-Human Rab geranylgeranyltransferase, beta subunit (RABGGTB)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RABGGTB
• Synonyms: GGTB
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_004582, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGCACTCCACAGAAGGATGTTATTATCAAGTCAGATGCACCGGACACTTTGTTATTGGAGAAACATG
  CAGATTATATCGCATCCTATGGCTCAAAGAAAGATGATTATGAATACTGTATGTCTGAGTATTTGAGAAT
  GAGTGGCATCTATTGGGGTCTGACAGTAATGGATCTCATGGGACAACTTCATCGCATGAATAGAGAAGAG
  ATTCTGGCATTTATTAAGTCTTGCCAACATGAATGTGGTGGAATAAGTGCTAGTATCGGACATGATCCTC
  ATCTTTTATACACTCTTAGTGCTGTCCAGATTCTTACGCTGTATGACAGTATTAATGTTATTGACGTAAA
  TAAAGTTGTGGAATATGTTAAAGGTCTACAGAAAGAAGATGGTTCTTTTGCTGGAGATATTTGGGGAGAA
  ATTGACACAAGATTCTCTTTTTGTGCGGTGGCAACTTTGGCTTTGTTGGGGAAGCTTGATGCTATTAATG
  TGGAAAAGGCAATCGAATTTGTTTTATCCTGTATGAACTTTGACGGTGGATTTGGTTGCAGACCAGGTTC
  TGAATCCCATGCTGGGCAGATCTATTGTTGCACAGGATTTCTGGCAATTACAAGTCAGTTGCATCAAGTA
  AATTCTGATTTACTTGGCTGGTGGCTTTGTGAACGACAATTACCCTCAGGCGGGCTCAATGGAAGGCCGG
  AGAAGTTACCAGATGTATGCTACTCATGGTGGGTCCTGGCTTCCCTAAAGATAATTGGAAGACTTCATTG
  GATTGATAGAGAGAAACTGCGTAATTTCATTTTAGCATGTCAAGATGAAGAAACGGGGGGATTTGCAGAC
  AGGCCAGGAGATATGGTGGATCCTTTTCATACCTTATTTGGAATTGCTGGATTGTCACTTTTGGGAGAAG
  AACAGATTAAACCTGTTAATCCTGTCTTTTGCATGCCTGAAGAAGTGCTTCAGAGAGTGAATGTTCAGCC
  TGAGCTAGTGAGCTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004582 unedited
  TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTTAGACATGGGCACT
  CCACAGAAGGATGTTATTATCAAGTCAGATGCACCGGACACTTTGTTATTGGAGAAACAT
  GCAGATTATATCGCATCCTATGGCTCAAAGAAAGATGATTATGTATGTATAATTTTTTTA
  TGTTGGAAAGTTTATTTTAAAGAAGTGTGACAGTCATAAGCAGTGAGACAGTATTTATGT
  CTTAAAATGGCATCCAACTCCATGCAGAGAACTGAGGATGTGCTGTGCCTTTGAACTTCA
  GTTAAGTGTGCTTTGGACGTCTGAGGCTGTGGGCTTATTAGAATCTCAGTTTTTACCTAT
  ACTGAGAGGGCTTGCCAGACAAAGTAGATGAGGGTTTGAGGTACAAAACGGGTTTCTCTT
  TTTGTAGTTAGGGGTAATACTTTCAAGGTCAATGATGTGTTGGCATGTATTATCTGAATC
  TATTGCTGATGTGTAATAACACTTTAGCTCTAGAATTACTCTGAGACCTTGAAAAAGTTT
  TACCTTAAATTTTTAAATTTCGAGGAAAACTCTGGGACAATCTTAGCAAAAAGTAGTAAA
  CAACTTAGTTAAGAGTAAATGTTTTTCCCTGTAGTATCCAAACTCAGTTGTCTTAGTCTA
  CCGATTTGTGGGATATATGGTATGTATTAATTNTTTACTTAAGTGTTANGTTCCCATAAC
  CTTNGAAATACCTCTATTAGCATCATGGAGTTAAGGCCATATGGATGGGNGCTGGACTCG
  TTTCTGCCTTTATCTGCTATCTATCTTTATGCCCTGAATNTGGGTTAGTAGCAACTAAGA
  GCACCACCTGTAAAAAAACTCTTTNTTCCTTTTAGAGCTTNACCTCACTTTGTGCCAGAC
  TGGAGAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004582 unedited
  TGTCCGCGGCCGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTTGTATAATTATATAA
  TTTATTAAAATTAATTTAACACAATATACAAAATATTAACAGTAGTCACTTTTAGATTCG
  ATAAGCACTTCAAATACAGAAATGTTAAAATGGCAAAACTATACTATGCAACTTTCAATT
  CAATGAATCTAGCTCACTAGCTCAGGCTGAACATTCACTCTCTGAAACACTTCTTCAGGC
  ATGCAAAAGACAGGATTAACAGGTTTAATCTGTTCTTCTCCCAAAAGTGACAATCCAGCA
  ATTCCAAATAAGGTATGAAAAGGATCCACCATATCTCCTGGCCTGTCTGCAAATCCCCCC
  GTTTCTTCATCTTGACATGCTAAAATGAAATTACGCAGTTTCTCTCTATCAATCCAATGA
  AGTCTTCCAATTATCTTTAGGGAAGCCAGGACCCCCCATGAGTAGCATACATCTGGGAAC
  TTCTCCGGCCTTCCATTGAGCCCGCCTGAGGGTAATTGTCGTTCACAAAGCCACCCGCCA
  AGTAAATCAAAATTTTACTTGATGCAACTGACTTGTAATTGCCAGAAATCCTGGGCAACA
  ATAGATCTGCCCACCCTGGGATCCAAAACCCGGTCTGCCACCCATTCCCCCGGTCAAGAT
  TATACAGGAAAAAACAAATACAATTGCCCTTTCCCCATTTAAACAATCACGCTTTCTCAC
  CAAAGCCAAATTGCCCCCCCCCACAAGAGAATCTTGGGTCTTTTCTCCCCAAATAATCCA
  GCCAGAGAACCACCTTTTTTTCTGTGACCTTCAGCTACTCCCCAATCTATTTTACCTCAA
  TAACTTAATACCTGCATACAGCGCACCATCCGGCCCGCCCAACAACGTCACAAAAACAGG
  CGCTGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004582
• Insert Size: 2740 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004582.2, NP_004573.2
• RefSeq Size: 1526 bp
• RefSeq ORF: 996 bp
• Locus ID: 5876
• Cytogenetics: 1p31.1
• Domains: prenyltrans
• Protein Families: Druggable Genome
• Gene Summary: 'This gene encodes the beta-subunit of the enzyme Rab geranylgeranyl-transferase (RabGGTase), which belongs to the protein prenyltransferase family. RabGGTase catalyzes the post-translational addition of geranylgeranyl groups to C-terminal cysteine residues of Rab GTPases. Three small nucleolar RNA genes are present in the intronic regions of this gene. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 3. [provided by RefSeq, Jan 2013]'
  Transcript Variant: This variant (1) encodes the supported protein.