RAB5C (NM_004583) Human Untagged Clone

CAT#: SC117292

RAB5C (untagged)-Human RAB5C, member RAS oncogene family (RAB5C), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RAB5C
• Synonyms: L1880; RAB5CL; RAB5L; RABL
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_004583 edited
  ATGGCGGGTCGGGGAGGCGCAGCACGACCCAATGGACCAGCTGCTGGGAACAAGATCTGT
  CAATTTAAGCTGGTTCTGCTGGGGGAGTCTGCGGTAGGCAAATCCAGCCTCGTCCTCCGC
  TTTGTCAAGGGACAGTTTCACGAGTACCAGGAGAGCACAATTGGAGCGGCCTTCCTCACA
  CAGACTGTCTGCCTGGATGACACAACAGTCAAGTTTGAGATCTGGGACACAGCTGGACAG
  GAGCGGTATCACAGCCTGGCCCCCATGTACTATCGGGGGGCCCAGGCTGCCATCGTGGTC
  TATGACATCACCAACACAGATACATTTGCACGGGCCAAGAACTGGGTGAAGGAGCTACAG
  AGGCAGGCCAGCCCCAACATCGTCATTGCACTCGCGGGTAACAAGGCAGACCTGGCCAGC
  AAGAGAGCCGTGGAATTCCAGGAAGCACAAGCCTATGCAGACGACAACAGTTTGCTGTTC
  ATGGAGACATCAGCAAAGACTGCAATGAACGTGAACGAAATCTTCATGGCAATAGCTAAG
  AAGCTTCCCAAGAACGAGCCCCAGAATGCAACTGGTGCTCCAGGCCGAAACCGAGGTGTG
  GACCTCCAGGAGAACAACCCAGCCAGCCGGAGCCAGTGCTGCAGCAACTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004583 unedited
  AATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGACCAGTCCCCACCCGCACG
  CTCTCTGGACCACTACAGCTGGACGGGCAATGGCGGGTCGGGGAGGCGCAGCACGACCCA
  ATGGACCAGCTGCTGGGAACAAGATCTGTCAATTTAAGCTGGTTCTGCTGGGGGAGTCTG
  CGGTAGGCAAATCCAGCCTCGTCCTCCGCTTTGTCAAGGGACAGTTTCACGAGTACCAGG
  AGAGCACAATTGGAGCGGCCTTCCTCACACAGACTGTCTGCCTGGATGACACAACAGTCA
  AGTTTGAGATCTGGGACACAGCTGGACAGGAGCGGTATCACAGCCTGGCCCCCATGTACT
  ATCGGGGGGCCCAGGCTGCCATCGTGGTCTATGACATCACCAACACAGATACATTTGCAC
  GGGCCAAGAACTGGGTGAAGGAGCTACAGAGGCAGGCCAGCCCCAACATCGTCATTGCAC
  TCGCGGGTAACAAGGCAGACCTGGCCAGCAAGAGAGCCGTGGAATTCCAGGAAGCACAAG
  CCTATGCAGACGACAACAGTTTGCTGTTCATGGAGACATCAGCAAAGACTGCAATGAACG
  TGAACGAAATCTTCATGGCAATAGCTAAGAAGCTTCCCAAGAACGAGCCCCAGAATGCAA
  CTGGTGCTCCAGGCCGAAACCGAGGTGTGGACCTTCAGGAGAACAACCCAGCCAGCCGGA
  GCCAGTGCTGCAGCAACTGAGCCCCCCTTGCCTGCCCGCTGTCCCCGCCTCCTCCGCCTG
  AATGACCCGACTGGAATCCACTCTACCAATCGCACTTAACGACTCCGGCCACACTGGGGG
  GGCAGGCGGGAAGGGGCCCACCCGGATTTCTCCTATAATTTGGATCTAGGGCCGGATTGA
  GCCATTCCACCTGCGCCCTTGTGTAAATATCCCATCCCATTTCTAACCCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004583 unedited
  GCTATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGAGGTCGAT
  CGATCGGCTGACTATATTGACAAGATACTGATTGGTTACATGTTGAAGAAAACATACAAT
  ACAAAATACAGAAAAAGTTGGTTCCGTCCCCTCCCACTCCCCCCCTTACCCACCCACCCC
  CAAATACTCATCATCATGATTTGGTCAGAACAGGGCTCAGAGCCAGAGGTTGGGGTGACC
  GAGGGTGGAGGGGTTGTGGGCAATGGGTTCGTGGCTGTCACAATAATGCTGTGATAATGC
  TGTGGTTTCCCAGCAGGGAGGTGGGAGCGGGGAGGGGGCTGCAGCCTGATGAGAGCCAGC
  TGAAGGAAGAGCTGCCTCTCCCTTCCTAAGCCCCTTCCCAAGGTCTGCCCCACCGCCCAA
  ACCAAAGACCACTCCGAACAAAGTGAGGATGTGGATGCTCTTGCTGGGTCCGCTGTTCCG
  CAGGAGGGAAAGAAAGGGTAGCTGCACTGACCCCACTGTCCCCATATACAAGGGTTGGGG
  GGCAAGAGCATGTGGCTACTCCCAGCAAGGGAAAATGGGAGAGCAGTANAAAGGGGAGGA
  AGTGGGAAGAGCAGAAGATCATATATATTAAAAAAGTGACTTAAGACTTAAAATTGAATT
  AGTATTTGTACAGAAAGGTGCANGTGGAATGACTCACTCCGGCCTATGATCAAAATTATA
  TGGAGAAATCATGGTGGACCCCTCCCCCTGCCCCCCCAGTGGTGGCCCCGAGTCGTTAAG
  TGCGATTGGTTAAAGTGGATTCCAGTCGGGTCATTCANGCGGAGGGAGCGGNGGCANCGG
  GCAGGCAAGGGGGGGCTCAATGCTGCACACTGGCTCCGCTGGCTGGGNTGTCTCCTGGAG
  GTCCACCTCGGTTTCGCCTGNACACAGTTGCATCTGGGCTCGTCTTGGGAGCTCCTAGCT
  ATGCATGAGATTCGTCCGTCATTGC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004583
• Insert Size: 1570 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004583.2, NP_004574.2
• RefSeq Size: 1674 bp
• RefSeq ORF: 651 bp
• Locus ID: 5878
• Cytogenetics: 17q21.2
• Domains: ras, RAN, RAS, RHO, RAB
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis
• Gene Summary: 'Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010]'
  Transcript Variant: This variant (2) lacks an exon in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (a).