TAPA1 (CD81) (NM_004356) Human Untagged Clone

CAT#: SC117455

CD81 (untagged)-Human CD81 molecule (CD81)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CD81
• Synonyms: CVID6; S5.7; TAPA1; TSPAN28
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_004356, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGAGTGGAGGGCTGCACCAAGTGCATCAAGTACCTGCTCTTCGTCTTCAATTTCGTCTTCTGGCTGG
  CTGGAGGCGTGATCCTGGGTGTGGCCCTGTGGCTCCGCCATGACCCGCAGACCACCAACCTCCTGTATCT
  GGAGCTGGGAGACAAGCCCGCGCCCAACACCTTCTATGTAGGCATCTACATCCTCATCGCTGTGGGCGCT
  GTCATGATGTTCGTTGGCTTCCTGGGCTGCTACGGGGCCATCCAGGAATCCCAGTGCCTGCTGGGGACGT
  TCTTCACCTGCCTGGTCATCCTGTTTGCCTGTGAGGTGGCCGCCGGCATCTGGGGCTTTGTCAACAAGGA
  CCAGATCGCCAAGGATGTGAAGCAGTTCTATGACCAGGCCCTACAGCAGGCCGTGGTGGATGATGACGCC
  AACAACGCCAAGGCTGTGGTGAAGACCTTCCACGAGACGCTTGACTGCTGTGGCTCCAGCACACTGACTG
  CTTTGACCACCTCAGTGCTCAAGAACAATTTGTGTCCCTCGGGCAGCAACATCATCAGCAACCTCTTCAA
  GGAGGACTGCCACCAGAAGATCGATGACCTCTTCTCCGGGAAGCTGTACCTCATCGGCATTGCTGCCATC
  GTGGTCGCTGTGATCATGATCTTCGAGATGATCCTGAGCATGGTGCTGTGCTGTGGCATCCGGAACAGCT
  CCGTGTACTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004356 unedited
  GTCAGAATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCCTCGTGCCG
  AATTCGGCACGAGGGACCGGCCCGCGCCCCGCAGGCCGCCCGCCGCCCGCGCCGCCATGG
  GAGTGGAGGGCTGCACCAAGTGCATCAAGTACCTGCTCTTCGTCTTCAATTTCGTCTTCT
  GGCTGGCTGGAGGCGTGATCCTGGGTGTGGCCCTGTGGCTCCGCCATGACCCGCAGACCA
  CCAACCTCCTGTATCTGGAGCTGGGAGACAAGCCCGCGCCCAACACCTTCTATGTAGGCA
  TCTACATCCTCATCGCTGTGGGCGCTGTCATGATGTTCGTTGGCTTCCTGGGCTGCTACG
  GGGCCATCCAGGAATCCCAGTGCCTGCTGGGGACGTTCTTCACCTGCCTGGTCATCCTGT
  TTGCCTGTGAGGTGGCCGCCGGCATCTGGGGCTTTGTCAACAAGGACCAGATCGCCAAGG
  ATGTGAAGCAGTTCTATGACCAGGCCCTACAGCAGGCCGTGGTGGATGATGACGCCNACA
  ACGCCAAGGCTGTGGTGAAGACCTTCCACGAGACGCTTGACTGCTGTGGCTCCAGCACAC
  TGACTGCTTTGACCACCTCAGTGCTCAAGAAACCATTGTGTCCCTCGGGCAGCAACATCA
  TCAGCAACCCTCTTCAAGGAGACTGCCACCAGAAGATCGATGACCTCTTCTCCGGGAAGC
  TGTACCTCATCGGCATTGCTGCCATCGTGGTCGCTGTGATCATGATCTTCGAGATGATCC
  TGAGCATGGTGCTGGGCTGTGGCATTCCGGACAGCTTCGTGTACTGAAGCCCCGCAGCTT
  TTGCCACAGGGACTCTTGGAGTGCCCCCTAAGTGACCGGCACCTCCGAGGGGGCCATAAC
  CGCTGGGATTTTACGTTTCCGGATTACCCTGCTACCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004356 unedited
  TTTCCTGTGTTCCCNTTTTTAAATGACGAGTCAGGCAGTTGTGATTACAGTTGAAGGCGA
  CGTGTTAGTAAAGGACAGGTGCATGAAGGCAGAGAGTGCCCACAGACTCGGCTCTCGAAC
  CGGGGCAGGAGGGAACAAGGTGAGCTGTGCAGCCCACAGGACGGGCGGGCTGGGTGGACA
  CAGCCCCCCAAGTTGGCCAAGCTGAGTCTCTGGGCGAGTGGCTCCCATGAGAGGCCTGGC
  TGAGCAGGCAGAGCACCCTGGGACCCCAGGGCAGAAGGACCCCTGCCCTCCAGTCCCCAA
  GACCCAGGCCCGTCTCCACTCATACACGCCACCTACATGTGACGTCAGCCCTGAAAAGGT
  AACAGGAAAGTTCAGAACAAAAACAAAACCCCAAAAGTAAAAAGGCTACGTGTAGCAGAG
  TAATACCGGAAACGTTATATACACAGGCGGTGATGGCCCCCTCGGAAGTGTCCGGGTCAC
  TTATGGGGCACTGCAGAGGTCCCTGTGGCCAGAGCTGCGGGGCCTCAGTACACGGAGCTG
  TTCCGGATGCCACAGCACAGCACCATGCTCATGATCATCTCGAAGATCATGATCACAGCG
  ACCACGATGGCAGCAATGCCGATGAGGTACAGCTTCCCGGAGAAGAGGTCATCGATCTTC
  TGGTGGCAGTCCTCCTTGAAGAGGTTGCTGATGATGTTGCTGCCCGAGGGACACAAATTG
  TTCTTGAGCACTGAGGTGGTCAAAGCAGTCAGTGTGCTGGAGCCACAGCAGTCAAGCGTC
  TCGTGGAAGGTCTTCACCACAGCCTTTGGGCGTTGTTGGCGTCATCATCCACCACGGCCT
  GCTGTAAGGCCTGGTCATAGAACTGCTTCACATCCTTGGCGATCTGGTCCTTGTTGACAT
  AGCCCAGATGCCGGCGGGCACTTACATGCAAACAGGATGACCATGCAGTTGAATAACGTC
  CC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004356
• Insert Size: 1400 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004356.3, NP_004347.1
• RefSeq Size: 1497 bp
• RefSeq ORF: 711 bp
• Locus ID: 975
• Cytogenetics: 11p15.5
• Domains: transmembrane4
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: B cell receptor signaling pathway
• Gene Summary: 'The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]'
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).