FKBP1B (NM_004116) Human Untagged Clone

CAT#: SC117568

FKBP1B (untagged)-Human FK506 binding protein 1B, 12.6 kDa (FKBP1B), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FKBP1B
• Synonyms: FKBP1L; FKBP12.6; OTK4; PKBP1L; PPIase
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_004116, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGCGTGGAGATCGAGACCATCTCCCCCGGAGACGGAAGGACATTCCCCAAGAAGGGCCAAACGTGTG
  TGGTGCACTACACAGGAATGCTCCAAAATGGGAAGAAGTTTGATTCATCCAGAGACAGAAACAAACCTTT
  CAAGTTCAGAATTGGCAAACAGGAAGTCATCAAAGGTTTTGAAGAGGGTGCAGCCCAGATGAGCTTGGGG
  CAGAGGGCGAAGCTGACCTGCACCCCTGATGTGGCATATGGAGCCACGGGCCACCCCGGTGTCATCCCTC
  CCAATGCCACCCTCATCTTTGACGTGGAGCTGCTCAACTTAGAGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004116 unedited
  GTTCAGGAATTATGTATACGACTCACTATAGGGNGACTCNCGCGAATCGGCACGAGGCCT
  CGTGCCGAATTCGGCACGAGGAGGAGGCGAGCCGGAGCGACGGAAGGACATTCCCCAAGA
  AGGGCCAAACGTGTGTGGTGCACTACACAGGAATGCTCCAAAATGGGAAGAAGTTTGATT
  CATCCAGAGACAGAAACAAACCTTTCAAGTTCAGAATTGGCAAACAGGAAGTCATCAAAG
  GTTTTGAAGAGGGTGCAGCCCAGATGAGCTTGGGGCAGAGGGCGAAGCTGACCTGCACCC
  CTGATGTGGCATATGGAGCCACGGGCCACCCCGGTGTCATCCCTCCCAATGCCACCCTCA
  TCTTTGACGTGGAGCTGCTCAACTTAGAGTGAAGGCAGGAAGGAACTCAAGGTGGCTGAC
  GATGGCTGCTGCTCACCCTCCTAGCCTGCTCTGCCACTGGGACGGCTCCTGCATTTGGGG
  CTCTTGATCAGTGTGCTAACCTCACTGCCTCATGGCATCATCCATTCTCTCTGCCCAAGT
  TGCTCTGTATGTGTTCGTCAGTGTTCATGCGAATTCTTGCTTGAGGAAACTTCGGTTGCA
  GATTGAAGCATTTCAGGTTGTGCATTTTGTGTGATGCATGTAGTAGCCTTTCCTGATGAC
  AGAACACAGATCTCTTGTTCGCACAATCTACACTGGCTTACCTTCACTTAAACCACACAC
  ACAAGGTGCTCAGACATGANATGTACATTGCGTACCGTACACAGAGGGACTTGAGCCAGT
  TACCTTTGCTGTCACTTTCTCTCTAATAAATTCTGGTAGCTGCTCACTTAAACATGTCCT
  CTTTGAAAAATGTAAAATAAAGGTTTTGTGCTTGACAAAAAAAAAAAAAAAACTCGACTC
  TAATATGCGGCCGCGGCATAGCTGTTTCCTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004116 unedited
  ATGGCACTTCCAGGGCCGGNAAAGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATC
  TGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTT
  TTGTCAAGCACAGAGCCTTTATTTTACATTTTCTCAAAGAGGACATTGTTTAAGTGAGCA
  GCTAACAGAATTTATAAGAGAGAAAGTGACAGCAAAGGTAACTGGCTCAAGTCCCTCTGT
  GTACGGTACGCCATGTACATTTCATGTCTGAGCACCTTGTGTGTGTGGTTTAAGTGAAGG
  TAAGGCAGTGTANATTGTGCGAACAAGAGATCTGTGTTCTGTCATCAGGAAAGGCTACTA
  CATGCATCACACAAAATGCACAACCTGAAATGCTTCAATCTGCAACCGAAGTTTCCTCAA
  GCAAGAATTCGCATGAACACTGACGAACACATACAGAGCAACTTGGGCAGAGAGAATGGA
  TGATGCCATGAGGCAGTGAGGTTAGCACACTGATCAAGAGCCCCAAAAGCAGGAGCCGTC
  CCAGTGGCAGAGCAGGCTAGGAGGGTGAGCAGCAGCCATCTCCAGCCACCTTGAGTTCCT
  TCCTGCCTTCACTCTAAGTTGAGCAGCTCCACGTCAAAGATGGAGGGTGGCATTGGGAGG
  GATGANCACCGGGTGGCCCGTGGCTCCATATGCCACATCAGGGGTGCAGGTCAGCTTCGC
  CCTCTGCCCAAGCTCATCTGGGCTGCACCTCTTCANAACTTTGATGACTTCCTGTTGCCA
  TTCTGAACTGAAAGTTTTGNTCTGTCTCTGGATGATCAAACTTCTTCCATTTTGGACATT
  CTGGGGTATGACCACCACGTTTGCCCTCTGGGGGATGCCCTTCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004116
• Insert Size: 840 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004116.2, NP_004107.1
• RefSeq Size: 971 bp
• RefSeq ORF: 327 bp
• Locus ID: 2281
• Cytogenetics: 2p23.3
• Domains: FKBP
• Protein Families: Druggable Genome
• Gene Summary: 'The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) uses an alternate splice site in the 3' coding region, compared to variant 2. The resulting isoform (a) has a longer and distinct C-terminus, compared to isoform a.