BCL2A1 (NM_004049) Human Untagged Clone

CAT#: SC117596

BCL2A1 (untagged)-Human BCL2-related protein A1 (BCL2A1), transcript variant 1


  "NM_004049" in other vectors (6)

Reconstitution Protocol

USD 310.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol BCL2A1
Synonyms ACC-1; ACC-2; ACC1; ACC2; BCL2L5; BFL1; GRS; HBPA1
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_004049 edited
GAATTCGGCACCAGCTTCAAGGTGAGCCAGCTCAAGACTTTGCTCTCCACCAGGCAGAAG
ATGACAGACTGTGAATTTGGATATATTTACAGGCTGGCTCAGGACTATCTGCAGTACGTC
CTACAGATACCACAACCTGGATCAGGTCCAAGCAAAACGTCCAGAGTGCTACAAAAGGTT
GCGTTCTCAGTCCAAAAAGAAGTGGAAAAGAATCTGAAGTCATGCTTGGACAATGTTAAT
GTTGTGTCCGTAGACACTGCCAGAACACTATTCAACCAAGTGATGGAAAAGGAGTTTGAA
GACGACATCATTAACTGGGGAAGAATTGTAACCATATTTGCATTTGAAGGTATTCTCATC
AAGAAACTTCTACGACAGCAAATTGCCCCGGATGTGGATACCTATAAGGAGATTTCATAT
TTTGTTGCGGAGTTCATAATGAATAACACAGGAGAATGGATAAGGCAAAACGGAGGCTGG
GAAAATGGCTTTGTAAAGAAGTTTGAACCTAAATCTGGCTGGATGACTTTTCTAGAAGTT
ACAGGAAAGATCTGTGAAATGCTATCTCTCCTGAAGCAATACTGTTGACCAGAAAGGACA
CTCCATATTGTGAAACCGGCCTAATTTTTCTGACTGATATGGAAACGATTGCCAACACAT
ACTTCTACTTTTAAATAAACAACTTTGATGATGTAACTTGACCTTCCAGAGTTATGGAAA
TTTTGTCCCCATGTAATGAATAAATTGTATGTATTTTTCTCTAAAAAAAAAAAAAAAAAA
AACTCGAC
>OriGene 5' read for NM_004049 unedited
CAAATTTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACCGCTTCAAGTGAGCCA
GCTCAAGACTTTGCTCTCCACCAGGCAGAAGATGACAGACTGTGAATTTGGATATATTTA
CAGGCTGGCTCAGGACTATCTGCAGTACGTCCTACAGATACCACAACCTGGATCAGGTCC
AAGCAAAACGTCCAGAGTGCTACAAAAGGTTGCGTTCTCAGTCCAAAAAGAAGTGGAAAA
GAATCTGAAGTCATGCTTGGACAATGTTAATGTTGTGTCCGTAGACACTGCCAGAACACT
ATTCAACCAAGTGATGGAAAAGGAGTTTGAAGACGACATCATTAACTGGGGAAGAATTGT
AACCATATTTGCATTTGAAGGTATTCTCATCAAGAAACTTCTACGACAGCAAATTGCCCC
GGATGTGGATACCTATAAGGAGATTTCATATTTTGTTGCGGAGTTCATAATGAATAACAC
AGGAGAATGGATAAGGCAAAACGGAGGCTGGGAAAATGGCTTTGTAAAGAAGTTTGAACC
TAAATCTGGCTGGATGACTTTTCTAGAAGTTACAGGAAAGATCTGTGAAATGCTATCTCT
CCTGAAGCAATACTGTTGACCAGAAAGGACACTCCATATTGTGAAACCGGCCTAATTTTT
CTGACTGATATGGAAACGATTGCCAACACATACTTCTACTTTTAAATAAACACTTTGATG
ATGTACTTGACCTTCAGAGTATGGANATTTGTCCCATGTATGAATAATTGTATGTATTTT
TCTCTAAAAAAAAAAAAAAACTCACTCTAGATGCGGNCGCGCATAGCTGTTCTGAACAAN
CCGGNTGGATCCTGGACCTNCCAGGCCTTCTGCCTTGAGTGCCATCATGCACAGCTGCTA
TAAATATGTCATGTGCAGCTATGTNGGGGGGGG
>OriGene 3' read for NM_004049 unedited
NGGGGCNANNNCNNNNNCNNNTNTTCNNNNAANGNTTTATTTTAGGCCCGCGGNCCGCAT
ACTAGGATCGAGTTTTTTTTTTTTTTTTTTTNTAGANAAAATACATACAATTTATTCATT
ACATGGGGACAAAATTTCCATAACTCTGGAAGGTCAAGTTACATCATCAAAGTTGTTTAT
TTAAAAGTAGAAGTATGTGTTGGCAATCGTTTCCATATCAGTCAGAAAAATTAGGCCGGT
TTCACAATATGGAGTGTCCTTTCTGGTCAACAGTATTGCTTCAGGAGAGATAGCATTTCA
CAGATCTTTCCTGTAACTTCTAGAAAAGTCATCCAGCCAGATTTAGGTTCAAACTTCTTT
ACAAAGCCATTTTCCCAGCCTCCGTTTTGCCTTATCCATTCTCCTGTGTTATTCATTATG
AACTCCGCAACAAAATATGAAATCTCCTTATAGGTATCCACATCCGGGGCAATTTGCTGT
CGTAGAAGTTTCTTGATGAGAATACCTTCAAATGCAAATATGGTTACAATTCTTCCCCAG
TTAATGATGTCGTCTTCAAACTCCTTTTCCATCACTTGGTTGAATAGTNGTCTGGCAGTG
TCTACGGACACAACATTAACATTTGTCCAGCATGACTTCAGATTCTTTTCCACTTTCTTT
TTGGACTGAGAACGCACCCTTTTGTAGCACTCTGGACGTTNTGCTTGGACCTGATCCAGG
TTGTGGTATCTGTAGGACGTACTGCAGATAGTCCTTGACCAGCCTGTAATATATCCCAAT
TCACAGTCTGTCATCTTCTGCCTGGTGGAAAGCAAAAGCCTTGAGCTGGCTCACCTTGAA
GCTGGTGCCGAATTCCCGGCCGCCTTATGGAGTCGTATAACAAATTTGACGGTTCACTAA
CGACTTTGCTATTAGGACTTCCACCGACACGCTACCGGCATTTGCGTAACGGGCCGGGTA
TTACCAATTTTGGAAAGTCCGTTGATTTGGGCCCAACCACTCCCTTGACGTAAGGGGGGG
GG
Restriction Sites NotI-NotI     
ACCN NM_004049
Insert Size 850 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_004049.2, NP_004040.1
RefSeq Size 885 bp
RefSeq ORF 528 bp
Locus ID 597
Cytogenetics 15q25.1
Domains Bcl-2
Protein Families Druggable Genome
Protein Pathways Metabolic pathways
Gene Summary 'This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (1) encodes the longer isoform (1).

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