ATOX1 (NM_004045) Human Untagged Clone

CAT#: SC117628

ATOX1 (untagged)-Human ATX1 antioxidant protein 1 homolog (yeast) (ATOX1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ATOX1
• Synonyms: ATX1; HAH1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117628 sequence for NM_004045 edited (data generated by NextGen Sequencing)
  ATGCCGAAGCACGAGTTCTCTGTGGACATGACCTGTGGAGGCTGTGCTGAAGCTGTCTCT
  CGGGTCCTCAATAAGCTTGGAGGAGTTAAGTATGACATTGACCTGCCCAACAAGAAGGTC
  TGCATTGAATCTGAGCACAGCATGGACACTCTGCTTGCAACCCTGAAGAAAACAGGAAAG
  ACTGTTTCCTACCTTGGCCTTGAGTAG
  
  Clone variation with respect to NM_004045.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004045 unedited
  GTAACGTCAGAATTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACCAGCACCG
  CCGCCACACCGCCGCCACACCGCCGCTGCCTCAGTCATGCCGAAGCACGAGTTCTCTGTG
  GACATGACCTGTGGAGGCTGTGCTGAAGCTGTCTCTCGGGTCCTCAATAAGCTTGGAGGA
  GTTAAGTATGACATTGACCTGCCCAACAAGAAGGTCTGCATTGAATCTGAGCACAGCATG
  GACACTCTGCTTGCAACCCTGAAGAAAACAGGAAAGACTGTTTCCTACCTTGGCCTTGAG
  TAGCAGGGGCCTGGTCCCCACAGCCCACAGGATGGACCAAAGGGGGCAGGATGCTGATCC
  TCCCGCTGGCTTCCAGACAGACCTGGGACTTGGCAGTCATGCCGGGTGATGGTGTTCCTG
  CGGAGACCCTCAGTTGTCCTATTCCTTCCTAGCTTCCCTGCAATAAAATCAAGCTGCTTT
  TGTTGGNAAANAAAAAAAANNNNNAAAAAAAAAAAAAAAAAAAAAAAAANAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAACCCTCGACTTTAGATTGCGGCCGCGGTCATAGCTGTTTCCT
  GAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCAAGTGCCTCTCCTGGCCCTGAAGG
  TTGCCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATTAAGTTGCATCATTTTGTCTG
  ACTAGGTGTCCTTCAAAAAATTTGGGGGAGGGGGGGGGGTTTATTTAAAACAAAGGGCAC
  TTTTGGAAAAAACCCTTGTGGGCCTGGGGGGTCTTTTTGGGAACCAACCTGGGGGTCGTT
  GGGCAATTCTGTGGCTCATTGAATTCCCCCCTCTGGGGTTAAAGCATTTTCTTGCTTCAA
  CCTCCG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004045
• Insert Size: 570 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004045.3, NP_004036.1
• RefSeq Size: 498 bp
• RefSeq ORF: 207 bp
• Locus ID: 475
• Cytogenetics: 5q33.1
• Domains: HMA
• Gene Summary: 'This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. [provided by RefSeq, Jul 2008]'