NFkB Inducing Kinase NIK (MAP3K14) (NM_003954) Human Untagged Clone

CAT#: SC117658

MAP3K14 (untagged)-Human mitogen-activated protein kinase kinase kinase 14 (MAP3K14)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MAP3K14
• Synonyms: FTDCR1B; HS; HSNIK; NIK
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003954 edited
  CCACGCGTCCGCGCAACACTCGCTTGGTTGGGGAGATCGGCGCTTGGCCGGATGAGCACA
  AGCCTGGGAGATGGCAGTGATGGAAATGGCCTGCCCAGGTGCCCCTGGCTCAGCAGTGGG
  GCAGCAGAAGGAACTCCCCAAAGCCAAGGAGAAGACGCCGCCACTGGGGAAGAAACAGAG
  CTCCGTCTACAAGCTTGAGGCCGTGGAGAAGAGCCCTGTGTTCTGCGGAAAGTGGGAGAT
  CCTGAATGACGTGATTACCAAGGGCACAGCCAAGGAAGGCTCCGAGGCAGGGCCAGCTGC
  CATCTCTATCATCGCCCAGGCTGAGTGTGAGAATAGCCAAGAGTTCAGCCCCACCTTTTC
  AGAACGCATTTTCATCGCTGGGTCCAAACAGTACAGCCAGTCCGAGAGTCTTGATCAGAT
  CCCCAACAATGTGGCCCATGCTACAGAGGGCAAAATGGCCCGTGTGTGTTGGAAGGGAAA
  GCGTCGCAGCAAAGCCCGGAAGAAACGGAAGAAGAAGAGCTCAAAGTCCCTGGCTCATGC
  AGGAGTGGCCTTGGCCAAACCCCTCCCCAGGACCCCTGAGCAGGAGAGCTGCACCATCCC
  AGTGCAGGAGGATGAGTCTCCACTCGGCGCCCCATATGTTAGAAACACCCCGCAGTTCAC
  CAAGCCTCTGAAGGAACCAGGCCTTGGGCAACTCTGTTTTAAGCAGCTTGGCGAGGGCCT
  ACGGCCGGCTCTGCCTCGATCAGAACTCCACAAACTGATCAGCCCCTTGCAATGTCTGAA
  CCACGTGTGGAAACTGCACCACCCCCAGGACGGAGGCCCCCTGCCCCTGCCCACGCACCC
  CTTCCCCTATAGCAGACTGCCTCATCCCTTCCCATTCCACCCTCTCCAGCCCTGGAAACC
  TCACCCTCTGGAGTCCTTCCTGGGCAAACTGGCCTGTGTAGACAGCCAGAAACCCTTGCC
  TGACCCACACCTGAGCAAACTGGCCTGTGTAGACAGTCCAAAGCCCCTGCCTGGCCCACA
  CCTGGAGCCCAGCTGCCTGTCTCGTGGTGCCCATGAGAAGTTTTCTGTGGAGGAATACCT
  AGTGCATGCTCTGCAAGGCAGCGTGAGCTCAGGCCAGGCCCACAGCCTGACCAGCCTGGC
  CAAGACCTGGGCAGCAAGGGGCTCCAGATCCCGGGAGCCCAGCCCCAAAACTGAGGACAA
  CGAGGGTGTCCTGCTCACTGAGAAACTCAAGCCAGTGGATTATGAGTACCGAGAAGAAGT
  CCACTGGGCCACGCACCAGCTCCGCCTGGGCAGAGGCTCCTTCGGAGAGGTGCACAGGAT
  GGAGGACAAGCAGACTGGCTTCCAGTGCGCTGTCAAAAAGGTGCGGCTGGAAGTATTTCG
  GGCAGAGGAGCTGATGGCATGTGCAGGATTGACCTCACCCAGAATTGTCCCTTTGTATGG
  AGCTGTGAGAGAAGGGCCTTGGGTCAACATCTTCATGGAGCTGCTGGAAGGTGGCTCCCT
  GGGCCAGCTGGTCAAGGAGCAGGGCTGTCTCCCAGAGGACCGGGCCCTGTACTACCTGGG
  CCAGGCCCTGGAGGGTCTGGAATACCTCCACTCACGAAGGATTCTGCATGGGGACGTCAA
  AGCTGACAACGTGCTCCTGTCCAGCGATGGGAGCCACGCAGCCCTCTGTGACTTTGGCCA
  TGCTGTGTGTCTTCAACCTGATGGCCTGGGAAAGTCCTTGCTCACAGGGGACTACATCCC
  TGGCACAGAGACCCACATGGCTCCGGAGGTGGTGCTGGGCAGGAGCTGCGACGCCAAGGT
  GGATGTCTGGAGCAGCTGCTGTATGATGCTGCACATGCTCAACGGCTGCCACCCCTGGAC
  TCAGTTCTTCCGAGGGCCGCTCTGCCTCAAGATTGCCAGCGAGCCTCCGCCTGTGAGGGA
  GATCCCACCCTCCTGCGCCCCTCTCACAGCCCAGGCCATCCAAGAGGGGCTGAGGAAAGA
  GCCCATCCACCGCGTGTCTGCAGCGGAGCTGGGAGGGAAGGTGAACCGGGCACTACAGCA
  AGTGGGAGGTCTGAAGAGCCCTTGGAGGGGAGAATATAAAGAACCAAGACATCCACCGCC
  AAATCAAGCCAATTACCACCAGACCCTCCATGCCCAGCCGAGAGAGCTTTCGCCAAGGGC
  CCCAGGGCCCCGGCCAGCTGAGGAGACAACAGGCAGAGCCCCTAAGCTCCAGCCTCCTCT
  CCCACCAGAGCCCCCAGAGCCAAACAAGTCTCCTCCCTTGACTTTGAGCAAGGAGGAGTC
  TGGGATGTGGGAACCCTTACCTCTGTCCTCCCTGGAGCCAGCCCCTGCCAGAAACCCCAG
  CTCACCAGAGCGGAAAGCAACCGTCCCGGAGCAGGAACTGCAGCAGCTGGAAATAGAATT
  ATTCCTCAACAGCCTGTCCCAGCCATTTTCTCTGGAGGAGCAGGAGCAAATTCTCTCGTG
  CCTCAGCATCGACAGCCTCTCCCTGTCGGATGACAGTGAGAAGAACCCATCAAAGGCCTC
  TCAAAGCTCGCGGGACACCCTGAGCTCAGGCGTACACTCCTGGAGCAGCCAGGCCGAGGC
  TCGAAGCTCCAGCTGGAACATGGTGCTGGCCCGGGGGCGGCCCACCGACACCCCAAGCTA
  TTTCAATGGTGTGAAAGTCCAAATACAGTCTCTTAATGGTGAACACCTGCACATCCGGGA
  GTTCCACCGGGTCAAAGTGGGAGACATCGCCACTGGCATCAGCAGCCAGATCCCAGCTGC
  AGCCTTCAGCTTGGTGACCAAAGACGGGCAGCCTGTTCGCTACGACATGGAGGTGCCAGA
  CTCGGGCATCGACCTGCAGTGCACACTGGCCCCTGATGGCAGCTTCGCCTGGAGCTGGAG
  GGTCAAGCATGGCCAGCTGGAGAACAGGCCCTAACCCTGCCCTCCACCGCCGGCTCCACA
  CTGCCGGAAGCAGCCTTCCTGCTCGGTGCACGATGCTGCCCTGAAACACAGGCTCAGCCG
  TTCCCAGGGATCTGCCAGCCCCCGGCTCAGCAGTGGGACCAGGGCCTCGCAGCAGCAAGG
  TGGGGGCAAGCAGAATGCCTCCCAGGATTTCACACCTGAGCCCTGCCCCACCCTGCTGAG
  AAAACACTCCGCCACGTGAAGAGACAGAGGAGGATGGCAGGAGTTACCTCGGGAAACAAA
  CAGGATCTTCTCTGCCCTGCTCCAGTCGAGTTGGCCTGACCCGCTTGGATCAGTGACCAT
  TTGCTGGCAGACAGGGGAGAGCAGCTTCCAGCCTGGGTCAGAAGGGGTGGGCGAGCCCCT
  CGGCCCCTCACCCTCCAGGCTGCTGTGAGAGTGTCAAGTGTGTAAGGGCCCAAACTCAGG
  TTCAGTGCAGAACCAGGTCAGCAGGTATGCCCGCCCGTAGGTTAAGGGGGCCCTCTAAAC
  CCCTTGCCTGGCCTCACCTGGCCAGCTCACCCCTTTTGGGTGTAGGGGAAAAGAATGCCT
  GACCCTGGGAAGGCTCCCTGGTAGAATACACCACACTTTTCAGGTTGTTGCAACACAGGT
  CCTGAGTTGACCTCTGGTTCAGCCAAGGACCAAAGAAGGTGTGTAAGTGAAGTGGTTCTC
  AGTCCCCAGACATGTGCCCCTTTGCTGCTGGCTACCACTCTTCCCCAGAGCAGCAGGCCC
  CGAGCCCCTTCAGGCCCAGCACTGCCCCAGACTCGCTGGCACTCAGTTCCCTCATCTGTA
  AAGGTGAAGGGTGATGCAGGATATGCCTGACAGGAACAGTCTGTGGATGGACATGATCAG
  TGCTAAGGAAAGCAGCAGAGAGAGACGCTCCGGCGCCCCAGCCCCACTATCAGTGTCCAG
  CGTGCTGGTTCCCCAGAGCACAGCTCAGCATCACACTGACACTCACCCTGCCCTGCCCCT
  GGCCAGAGGGTACTGCCGACGGCACTTTGCACTCTGATGACCTCAAAGCACTTTCATGGC
  TGCCCTCTGGCAGGGCAGGGTAGGGCAGTGACACTGTAGGAGCATAGCAAGCCAGGAGAT
  GGGGTGAAGGGACACAGTCTTGAGCTGTCCACATGCATGTGACTCCTCAAACCTCTTCCA
  GATTTCTCTAAGAATAGCACCCCCTTCCCCATTGCCCCAGCTTAGCCTCTTCTCCCAGGG
  GAGCTACTCAGGACTCACGTAGCATTAAATCAGCTGTGAATCGTCAGGGGGTGTCTGCTA
  GCCTCAACCTCCTGGGGCAGGGGACGCCGAGACTCCGTGGGAGAAGCTCATTCCCACATC
  TTGCCAAGACAGCCTTTGTCCAGCTGTCCACATTGAGTCAGACTGCTCCCGGGGAGAGAG
  CCCCGGCCCCCAGCACATAAAGAACTGCAGCCTTGGTACTGCAGAGTCTGGGTTGTAGAG
  AACTCTTTGTAAGCAATAAAGTTTGGGGTGATGACAAATGTTAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003954 unedited
  CCTTCGAGATTTCGTAAACGTACTCACTATAGGGNCGTGGCGCGCAATTCCCGGGGATAT
  CGTTCGACCCACGCGTCCGCGCAACACTCGCTTGGTTGGGGAGATCGGCGCTTGGCCGGA
  TGAGCACAAGCCTGGGAGATGGCAGTGATGGAAATGGCCTGCCCAGGTGCCCCTGGCTCA
  GCAGTGGGGCAGCAGAAGGAACTCCCCAAAGCCAAGGAGAAGACGCCGCCACTGGGGAAG
  AAACAGAGCTCCGTCTACAAGCTTGAGGCCGTGGAGAAGAGCCCTGTGTTCTGCGGAAAG
  TGGGAGATCCTGAATGACGTGATTACCAAGGGCACAGCCAAGGAAGGCTCCGAGGCAGGG
  CCAGCTGCCATCTCTATCATCGCCCAGGCTGAGTGTGAGAATAGCCAAGAGTTCAGCCCC
  ACCTTTTCAGAACGCATTTTCATCGCTGGGTCCAAACAGTACAGCCAGTCCGAGAGTCTT
  GATCAGATCCCCAACAATGTGGCCCATGCTACAGAGGGCAAAATGGCCCGTGTGTGTTGG
  AAGGGAAAGCGTCGCAGCAAAGCCCGGAAGAAACGGAAGAAGAAGAGCTCANAGTCCCTG
  GCTCATGCANGAGTGGCCTTGGCCAAACCCCTCCCCAGGACCCCTGAGCAGGAGAGCTGC
  ACCATCCCAGTGCANGAGGATGAGTCTCCACTCGGCGCCCCATATGTTAGAAACACCCCG
  CAGTTCACCAAGCCTCTGAAAGAACCANGCCTNGAGCAACTCTGTTTTAAGCAGCTTGGC
  GAGGGCCTACGGCCGGCTCTGCCTCGATCAGGACTCCACAACTGATCAGCCCCTTGGCAT
  GTCTGGACCACGTGTGGNAACTGCACCACCCCAGGACGGAGCCCCCTTGCCCTGCCACGC
  CCCCTTTCCCTTAAGNAAACTGCTCATACCTTCCATGCACCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003954 unedited
  TGNGGGGGGTTCTTTGNNACCGCGGCCGCCCTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TAACAATTGTCATCACCCCAAACTTTATTGCTTACAAAAAGTTCTCTACAACCCAAACTC
  TGCAGTACCAAGGCTGCAGTTCTTTATGTGCTGGGGGCCGGGGCTCTCTCCCCGGGAGCA
  GTCTGACTCAATGTGGACAGCTGGACAAAGGCTGTCTTGGCAAGATGTGGGAATGAGCTT
  CTCCCACGGAGTCTCGGCGTCCCCTGCCCCAGGAGGTTGAGGCTAGCAAACACCCCCTGA
  CGATTCACAGCTGATTTAATGCTACGTGAGTCCTGAGTAGCTCCCCTGGGAGAAGAGGCT
  AAGCTGGGGCAATGGGGAAGGGGGTGCTATTCTTAGAGAAATCTGGAAGAGGTTTGAGGA
  GTCACATGCATGTGGACAGCTCAAGACTGTGTCCCTTCACCCCATCTCCTGGCTTGCTAT
  GCTCCTACAGTGTCACTGCCCTACCCTGCCCTGCCAGAGGGCAGCCATGAAAGTGCTTTG
  AGGTCATCAGAGTGCAAAGTGCCGTCGGCAGTACCCTCTGGCCAGGGGCAGGGCAGGGTG
  AGTGTCAGTGTGATGCTGAGCTGTGCTCTGGGGAACCAGCACGCTGGACACTGATAGTGG
  GGCTGGGGCGCCGGAACGTCTCTCTCTGCTGCTTTCCTTAGCACTGATCATGTCCATCCA
  CAGACTGTTCCTGTCAAGCATATCCTGCATCACCCTTCACCTTTACAGATGAGGGAACTG
  AGTGCCAGCGAGTCTGGGGCAGTGCTGGGCCTGAAGGGGCTCTGGGCCTGCTGCTCTGGG
  GAAGAGTGGTAGCCAGCANNCAAGGGGCACATGTCTGG
  
• Restriction Sites: Please inquire
• ACCN: NM_003954
• ORF Size: 2844 bp
• Insert Size: 4600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003954.1, NP_003945.1
• RefSeq Size: 4596
• RefSeq ORF: 2844
• Locus ID: 9020
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Apoptosis, Epithelial cell signaling in Helicobacter pylori infection, MAPK signaling pathway, T cell receptor signaling pathway
• Gene Summary: This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]