AGXT (NM_000030) Human Untagged Clone

CAT#: SC117664

AGXT (untagged)-Human alanine-glyoxylate aminotransferase (AGXT)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AGXT
• Synonyms: AGT; AGT1; AGXT1; PH1; SPAT; SPT; TLH6
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_000030, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCTCTCACAAGCTGCTGGTGACCCCCCCCAAGGCCCTGCTCAAGCCCCTCTCCATCCCCAACCAGC
  TCCTGCTGGGGCCTGGTCCTTCCAACCTGCCTCCTCGCATCATGGCAGCCGGGGGGCTGCAGATGATCGG
  GTCCATGAGCAAGGATATGTACCAGATCATGGACGAGATCAAGGAAGGCATCCAGTACGTGTTCCAGACC
  AGGAACCCACTCACACTGGTCATCTCTGGCTCGGGACACTGTGCCCTGGAGGCCGCCCTGGTCAATGTGC
  TGGAGCCTGGGGACTCCTTCCTGGTTGGGGCCAATGGCATTTGGGGGCAGCGAGCCGTGGACATCGGGGA
  GCGCATAGGAGCCCGAGTGCACCCGATGACCAAGGACCCTGGAGGCCACTACACACTGCAGGAGGTGGAG
  GAGGGCCTGGCCCAGCACAAGCCAGTGCTGCTGTTCTTAACCCACGGGGAGTCGTCCACCGGCGTGCTGC
  AGCCCCTTGATGGCTTCGGGGAACTCTGCCACAGGTACAAGTGCCTGCTCCTGGTGGATTCGGTGGCATC
  CCTGGGCGGGACCCCCCTTTACATGGACCGGCAAGGCATCGACATCCTGTACTCGGGCTCCCAGAAGGCC
  CTGAACGCCCCTCCAGGGACCTCGCTCATCTCCTTCAGTGACAAGGCCAAAAAGAAGATGTACTCCCGCA
  AGACGAAGCCCTTCTCCTTCTACCTGGACATCAAGTGGCTGGCCAACTTCTGGGGCTGTGACGACCAGCC
  CAGGATGTACCATCACACAATCCCCGTCATCAGCCTGTACAGCCTGAGAGAGAGCCTGGCCCTCATTGCG
  GAACAGGGCCTGGAGAACAGCTGGCGCCAGCACCGCGAGGCCGCGGCGTATCTGCATGGGCGCCTGCAGG
  CACTGGGGCTGCAGCTCTTCGTGAAGGACCCGGCGCTCCGGCTTCCCACAGTCACCACTGTGGCTGTACC
  CGCTGGCTATGACTGGAGAGACATCGTCAGCTACGTCATAGACCACTTCGACATTGAGATCATGGGTGGC
  CTTGGGCCCTCCACGGGGAAGGTGCTGCGGATCGGCCTGCTGGGCTGCAATGCCACCCGCGAGAATGTGG
  ACCGCGTGACGGAGGCCCTGAGGGCGGCCCTGCAGCACTGCCCCAAGAAGAAGCTGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000030 unedited
  GAATTTGTAATACGACTCACTATAGGGCGGCCCGCGAATTCGCACGAGCCAGGTTCCCGA
  GCGGCAGGTTGGGTGCGGACCCATGGCCTCTCACAAGCTGCTGGTGACCCCCCCCAGGCC
  CTGCTCAAGCCCCTCTCCATCCCCAACCAGCTCCTGCTGGGGCCTGGTCCTTCCAACCTG
  CCTCCTCGCATCATGGCAGCCGGGGGGCTGCAGATGATCGGGTCCATGAGCAAGGATATG
  TACCAGATCATGGACGAGATCAAGGAAGGCATCCAGTACGTGTTCCAGACCAGGAACCCA
  CTCACACTGGTCATCTCTGGCTCAGGACACTGTGCCCTGGAGGCCGCCCTGGTCAATGTG
  CTGGAGCCTGGGGACTCCTTCCTGGTTGGGGCCAATGGCATTTGGGGGCAGCGAGCCGTG
  GACATCGGGGAGCGCATAGGAGCCCGAGTGCACCCGATGACCAAGGACCCTGGAGGCCAC
  TACACACTGCAGGAGGTGGAGGAGGGCCTGGCCCAGCACAAGCCAGTGCTGCTGTTCTTA
  ACCCACGGNGAGTCGTCCACCGGCGTGCTGCAGCCCCTTGATGGCTTCGGNGAACTCTGC
  CACAGGTACAAGTGCCTGCTCCTGGTGGATTCGGTGGCATCCCTGGGCGGGACCCCCCTT
  TACATGGACCGGNCAGGCATCGACATCCTGTACTCGGGCTCCCAGAAGCCCCTGACGCCC
  CTNNCAGGACCTCGCTCATCTCCTTCAGTGACAGGCCCAAAAGAAGATGTACTCCCGCAA
  GAGAAGCCCTCCTCCTCTACCTGGACATAATGGCTGGGCACTTCGGGGCTGGTCGACCAG
  CCCAGATGTACATNACACATTCCCGCATCAGCCTGTACAGCCGANAGAGAGGCTGCCCTC
  ATGCCGGACAGGCCTGAAAACAATGGCGCACACCGGAGGCCGCGCGTATTGCTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000030 unedited
  CCCCCCCATTCGTGTGNNACCGCGGNNCCGCATTCTAGGANCGGCTTTTTTTTTTTTTTT
  TTTGTGAGGAGAGGTGGCCAGGCCCTTTATTAAACATTCCCGGGAGGCTCATGGCCTGGG
  GACTGCAGCTCATTTGGAAGGCACTGGGTTTTGCGCCCAAGTGGACTGTTTCCAGGAGGT
  GCCACTGGAGGGAAAAGGGCTGCCTGGGGCCAGGGAGGCTGCCTGGTTCTGCCTCCCGGG
  CTGGGTCAGTGGCTTTCCTGTCCCCAGGCCTGGAGGACCTTGCAGGGTCTGTTTGCTCCT
  GATCCCTCAGGGTGGGCATGGGACAGGTGTGTGCCAGTGCCAGCTGTGTGCCAGTGGGCA
  GGTCACAGCTTCTTCTTGGGGCAGTGCTGCAGGGCCGCCCTCAGGGCCTCCGTCACGCGG
  TCCACATTCTCGCGGGTGGCATTGCAGCCCAGCAGGCCGATCCGCAGCACCTTCCCCGTG
  GAGGGCCCAAGGCCACCCATGATCTCAATGTCGAAGTGGTCTATGACGTAGCTGACGATG
  TCTCTCCAGTCATAGCCAGCGGGTACAGCCACAGTGGTGACTGTGGGAAGCCGGAGCGCC
  GGGTCCTTCACGAAGAGCTGCAGCCTCAGTGCCTGCAGGCGCCCATGCAGATACGCCGCG
  GCCTCGCGGTGCTGGCGCCAGCTGTTCTCCAGGCCCTGTTCCGCAATGAGGGCCAGGCTC
  TCTCTCAGGCTGTACAGGCTGATGACGGGGGAATTGTGNGAAGGGACACCCTTNGCCTGG
  TCGGCACAGCCCCAGAAGTTGGCCCCCCACTTGATGTCCAGGCTACAGGGGAAAGCCCTC
  TTCTTGCGGGAGATATATTCTTTATTGCCATGTACATTCCAGGAAATATTCGGCCCTCTG
  CAGCACCCCCCACTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000030
• ORF Size: 1179 bp
• Insert Size: 1710
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_000030.1, NP_000021.1
• RefSeq Size: 1600
• RefSeq ORF: 1179
• Locus ID: 189
• Domains: aminotran_5
• Protein Families: Druggable Genome
• Protein Pathways: Alanine, aspartate and glutamate metabolism, Glycine, serine and threonine metabolism, Metabolic pathways
• Gene Summary: This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq, Jul 2008]