KAT2B (NM_003884) Human Untagged Clone

CAT#: SC117692

KAT2B (untagged)-Human K(lysine) acetyltransferase 2B (KAT2B)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KAT2B
• Synonyms: CAF; P/CAF; PCAF
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_003884, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCCGAGGCTGGCGGGGCCGGGCCGGGCGGCTGCGGGGCAGGAGCCGGGGCAGGGGCCGGGCCCGGGG
  CGCTGCCCCCGCAGCCTGCGGCGCTTCCGCCCGCGCCCCCGCAGGGCTCCCCCTGCGCCGCTGCCGCCGG
  GGGCTCGGGCGCCTGCGGTCCGGCGACGGCAGTGGCTGCAGCGGGCACGGCCGAAGGACCGGGAGGCGGT
  GGCTCGGCCCGAATCGCCGTGAAGAAAGCGCAACTACGCTCCGCTCCGCGGGCCAAGAAACTGGAGAAAC
  TCGGAGTGTACTCCGCCTGCAAGGCCGAGGAGTCTTGTAAATGTAATGGCTGGAAAAACCCTAACCCCTC
  ACCCACTCCCCCCAGAGCCGACCTGCAGCAAATAATTGTCAGTCTAACAGAATCCTGTCGGAGTTGTAGC
  CATGCCCTAGCTGCTCATGTTTCCCACCTGGAGAATGTGTCAGAGGAAGAAATGAACAGACTCCTGGGAA
  TAGTATTGGATGTGGAATATCTCTTTACCTGTGTCCACAAGGAAGAAGATGCAGATACCAAACAAGTTTA
  TTTCTATCTATTTAAGCTCTTGAGAAAGTCTATTTTACAAAGAGGAAAACCTGTGGTTGAAGGCTCTTTG
  GAAAAGAAACCCCCATTTGAAAAACCTAGCATTGAACAGGGTGTGAATAACTTTGTGCAGTACAAATTTA
  GTCACCTGCCAGCAAAAGAAAGGCAAACAATAGTTGAGTTGGCAAAAATGTTCCTAAACCGCATCAACTA
  TTGGCATCTGGAGGCACCATCTCAACGAAGACTGCGATCTCCCAATGATGATATTTCTGGATACAAAGAG
  AACTACACAAGGTGGCTGTGTTACTGCAACGTGCCACAGTTCTGCGACAGTCTACCTCGGTACGAAACCA
  CACAGGTGTTTGGGAGAACATTGCTTCGCTCGGTCTTCACTGTTATGAGGCGACAACTCCTGGAACAAGC
  AAGACAGGAAAAAGATAAACTGCCTCTTGAAAAACGAACTCTAATCCTCACTCATTTCCCAAAATTTCTG
  TCCATGCTAGAAGAAGAAGTATATAGTCAAAACTCTCCCATCTGGGATCAGGATTTTCTCTCAGCCTCTT
  CCAGAACCAGCCAGCTAGGCATCCAAACAGTTATCAATCCACCTCCTGTGGCTGGGACAATTTCATACAA
  TTCAACCTCATCTTCCCTTGAGCAGCCAAACGCAGGGAGCAGCAGTCCTGCCTGCAAAGCCTCTTCTGGA
  CTTGAGGCAAACCCAGGAGAAAAGAGGAAAATGACTGATTCTCATGTTCTGGAGGAGGCCAAGAAACCCC
  GAGTTATGGGGGATATTCCGATGGAATTAATCAACGAGGTTATGTCTACCATCACGGACCCTGCAGCAAT
  GCTTGGACCAGAGACCAATTTTCTGTCAGCACACTCGGCCAGGGATGAGGCGGCAAGGTTGGAAGAGCGC
  AGGGGTGTAATTGAATTTCACGTGGTTGGCAATTCCCTCAACCAGAAACCAAACAAGAAGATCCTGATGT
  GGCTGGTTGGCCTACAGAACGTTTTCTCCCACCAGCTGCCCCGAATGCCAAAAGAATACATCACACGGCT
  CGTCTTTGACCCGAAACACAAAACCCTTGCTTTAATTAAAGATGGCCGTGTTATTGGTGGTATCTGTTTC
  CGTATGTTCCCATCTCAAGGATTCACAGAGATTGTCTTCTGTGCTGTAACCTCAAATGAGCAAGTCAAGG
  GCTATGGAACACACCTGATGAATCATTTGAAAGAATATCACATAAAGCATGACATCCTGAACTTCCTCAC
  ATATGCAGATGAATATGCAATTGGATACTTTAAGAAACAGGGTTTCTCCAAAGAAATTAAAATACCTAAA
  ACCAAATATGTTGGCTATATCAAGGATTATGAAGGAGCCACTTTAATGGGATGTGAGCTAAATCCACGGA
  TCCCGTACACAGAATTTTCTGTCATCATTAAAAAGCAGAAGGAGATAATTAAAAAACTGATTGAAAGAAA
  ACAGGCACAAATTCGAAAAGTTTACCCTGGACTTTCATGTTTTAAAGATGGAGTTCGACAGATTCCTATA
  GAAAGCATTCCTGGAATTAGAGAGACAGGCTGGAAACCGAGTGGAAAAGAGAAAAGTAAAGAGCCCAGAG
  ACCCTGACCAGCTTTACAGCACGCTCAAGAGCATCCTCCAGCAGGTGAAGAGCCATCAAAGCGCTTGGCC
  CTTCATGGAACCTGTGAAGAGAACAGAAGCTCCAGGATATTATGAAGTTATAAGGTTCCCCATGGATCTG
  AAAACCATGAGTGAACGCCTCAAGAATAGGTACTACGTGTCTAAGAAATTATTCATGGCAGACTTACAGC
  GAGTCTTTACCAATTGCAAAGAGTACAACCCCCCTGAGAGTGAATACTACAAATGTGCCAATATCCTGGA
  GAAATTCTTCTTCAGTAAAATTAAGGAAGCTGGATTAATTGACAAGTGA
  
  
• Restriction Sites: Please inquire
• ACCN: NM_003884
• ORF Size: 2499 bp
• Insert Size: 4800
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: TrueClone

Reference Data

• RefSeq: NM_003884.3, NP_003875.3
• RefSeq Size: 4838
• RefSeq ORF: 2499
• Locus ID: 8850
• Domains: Acetyltransf, BROMO
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Notch signaling pathway
• Gene Summary: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008]