SCAP2 (SKAP2) (NM_003930) Human Untagged Clone

CAT#: SC117697

SKAP2 (untagged)-Human src kinase associated phosphoprotein 2 (SKAP2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SKAP2
• Synonyms: PRAP; RA70; SAPS; SCAP2; SKAP-HOM; SKAP55R
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117697 sequence for NM_003930 edited (data generated by NextGen Sequencing)
  ATGCCCAACCCCAGCAGCACCTCCTCTCCCTACCCCCTCCCTGAGGAAATTAGGAACCTG
  TTGGCAGATGTTGAAACATTTGTAGCAGATATACTGAAAGGAGAAAATTTATCCAAGAAA
  GCAAAGGAAAAGAGAGAATCCCTTATTAAGAAGATAAAAGATGTAAAGTCTATCTATCTT
  CAGGAATTTCAAGACAAAGGTGATGCAGAAGATGGGGAAGAATATGATGACCCTTTTGCT
  GGGCCTCCAGACACTATTTCATTAGCCTCAGAACGATATGATAAAGACGATGAAGCCCCC
  TCTGATGGAGCCCAGTTTCCTCCAATTGCAGCACAAGACCTTCCTTTTGTTCTAAAGGCT
  GGCTACCTTGAAAAACGCAGAAAAGATCACAGCTTTCTGGGATTTGAATGGCAGAAACGG
  TGGTGTGCTCTCAGTAAAACGGTATTCTATTATTATGGAAGTGATAAAGACAAACAACAG
  AAAGGTGAATTTGCAATAGATGGCTACAGTGTCAGAATGAATAACACTCTAAGAAAGGAT
  GGAAAGAAAGATTGCTGTTTTGAAATCTCTGCTCCTGATAAACGTATATATCAGTTTACA
  GCAGCTTCTCCCAAAGATGCTGAAGAATGGGTACAGCAGCTGAAATTTGTATTGCAAGAT
  ATGGAATCTGATATTATTCCTGAGGATTATGATGAGAGAGGAGAATTATATGATGATGTT
  GATCATCCTCTACCAATAAGCAATCCACTAACAAGCAGTCAACCAATAGATGATGAAATT
  TATGAAGAACTTCCAGAAGAAGAAGAGGACAGTGCTCCAGTGAAAGTGGAAGAACAAAGG
  AAGATGAGTCAGGATAGTGTCCATCACACCTCAGGGGATAAGAGCACTGATTATGCTAAT
  TTTTACCAGGGATTGTGGGATTGTACTGGAGCTTTTTCTGATGAGTTGTCATTTAAGCGT
  GGTGATGTGATTTACATTCTTAGCAAGGAATACAATAGATATGGCTGGTGGGTAGGAGAA
  ATGAAGGGAGCCATTGGCTTGGTGCCTAAAGCCTACATAATGGAGATGTATGATATTTGA
  
  Clone variation with respect to NM_003930.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003930 unedited
  CGTCAAAATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGGCTCGCTGG
  AGATTCAGTGACTTCCTTGTTGTGAGCCCCGGCCCGGCAGTGTCCCGACTCGTAGCCCCG
  CTGTTCTTAATCCGGGCCGCTAGCCTGAGTCTAGGTCGCAGCCGCAGCCCCACCCCGTCG
  GTCACCTTTTCAGCGCAGGTCCTTTCCCCGCACGCCCTGCGCTCCCTAACATGCCCAACC
  CCAGCAGCACCTCCTCTCCCTACCCCCTCCCTGAGGAAATTAGGAACCTGTTGGCAGATG
  TTGAAACATTTGTAGCAGATATACTGAAAGGAGAAAATTTATCCAAGAAAGCAAAGGAAA
  AGAGAGAATCCCTTATTAAGAAGATAAAAGATGTAAAGTCTATCTATCTTCAGGAATTTC
  AAGACAAAGGTGATGCAGAAGATGGGGAAGAATATGATGACCCTTTTGCTGGGCCTCCAG
  ACACTATTTCATTAGCCTCAGAACGATATGATAAAGACGATGAAGCCCCCTCTGATGGAG
  CCCAGTTTCCTCCAATTGCAGCACAAGACCTTCCTTTTGTTCTAAAGGCTGGCTACCTTG
  AAAAACGCAGAAAAGATCACAGCTTTCTGGGATTTGAATGGCAGAAACGGNTGGGTGTGC
  TCTCAGTAAAACGGTATTCTATTATTATGGAAGTGATAAAGACAAACAACAGAAAGGTGA
  ATTTGCAATAGATGGCTACAGTGTCAGAATGAATAACACTCTAAGAAAGGGATGGAAAGA
  AGATTGCTGTTNTGAAATCTCTGCTCCTGATNAACGTATATATCAGTTTACAGCAGCTTC
  TCCCAAGATGCTNGAGAATGGGTACAGCAGCTGAAAATTGTATTGCAGATATGGAATCTG
  ATATTATTCCTGAGGATATGATGAGAGAGGAGAATATTGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003930 unedited
  GCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCTGAGAGGAGTCTCACTCTGTCG
  CCCAGGCTGGAGTGCAAAGGAGCGATCTTGGCTAACTGCAACCTCTGCCTACCTTGTTCA
  AGCATTTCTCGTGCCTTGGCCTCCCAATTACCTGGGACTGCAGGTGAACATTACCACACT
  TGGCTAATTTTTATTACATACAGGGTTTTACCATGTTGGCCTGGCTGGGAGATTCTTTAT
  ACCATTTTGTTAGTGGCAGGGTGGTATTTCTTAAGAATTTTTTGCTTCATTAAATTTAAA
  CCTAAGTCCTGTATAAAATGTTGCCAGGCCCATCATCGCACCAGGATATTTGTACCGTAA
  AATGCTTTGCATGAGTCATACTTCTGGTACGCACTTCTGTTGCAGGCGACAGCTCACTGC
  CATTTGCAACTTCATCATTTTTTCTTTCTTGCGGCTGTACTTAATACGAATCAAATGTGT
  GAAAATACCTAATGACAATACAGTCGTCTATAACGTTTGAACATTCTTTTACATTCTTTG
  GTTATCAACCACATTCTTCAGCATCTACCAAAAAAGACTCGCATGATACACTAAATTTAA
  AATGCTATGAATTAACTCCTTACTCTCTAAAAATATTCGATGTCCAATGATCAAGAAACT
  TAGCAATCACCCCGGATTACCTTAGTGCCTACTATGCTTAGCAGACTCTTTGTACCCCTA
  AAATTGGGATGAATTCTTCCCCCAAATAAATGGGTAAATAAAAACCTTGATTTTTTCTTT
  GCAAAAACCACAGGTTTAACTTACCGGGCTGGCTTAACTTTACCTAATTTCCCTCCTTAA
  TTTCACACCAAAGCATTCCTTTACCCCCGTCCGCTCCAAAACGCCTAACCTCATCAATGT
  TTATAATAAAAGGAAAGGTAGGAGCGGCCACGCGTGCTTAAGACCTCCTTAATCAAGGCT
  GTGGAATACACAAGATAATCTTTCCAAACT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003930
• ORF Size: 1080 bp
• Insert Size: 2500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003930.3, NP_003921.2
• RefSeq Size: 3984
• RefSeq ORF: 1080
• Locus ID: 8935
• Domains: SH3, PH
• Gene Summary: The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).