WAVE 1 (WASF1) (NM_003931) Human Untagged Clone

CAT#: SC117699

WASF1 (untagged)-Human WAS protein family, member 1 (WASF1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: WASF1
• Synonyms: SCAR1; WAVE; WAVE1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117699 sequence for NM_003931 edited (data generated by NextGen Sequencing)
  ATGCCGCTAGTGAAAAGAAACATCGATCCTAGGCACTTGTGCCACACAGCACTGCCTAGA
  GGCATTAAGAATGAACTGGAATGTGTAACCAATATTTCCTTGGCAAATATAATTAGACAA
  CTAAGTAGCCTAAGTAAATATGCTGAAGATATATTTGGAGAATTATTCAATGAAGCACAT
  AGTTTTTCCTTCAGAGTCAACTCATTGCAAGAACGTGTGGACCGTTTATCTGTTAGTGTT
  ACACAGCTTGATCCAAAGGAAGAAGAATTGTCTTTGCAAGATATAACAATGAGGAAAGCT
  TTCCGAAGTTCTACAATTCAAGACCAGCAGCTTTTCGATCGCAAGACTTTGCCTATTCCA
  TTACAGGAGACGTACGATGTTTGTGAACAGCCTCCACCTCTCAATATACTCACTCCTTAT
  AGAGATGATGGTAAAGAAGGTCTGAAGTTTTATACCAATCCTTCGTATTTCTTTGATCTA
  TGGAAAGAAAAAATGTTGCAAGATACAGAGGATAAGAGGAAGGAAAAGAGGAAGCAGAAG
  CAGAAAAATCTAGATCGTCCTCATGAACCAGAAAAAGTGCCAAGAGCACCTCATGACAGG
  CGGCGAGAATGGCAGAAGCTGGCCCAAGGTCCAGAGCTGGCTGAAGATGATGCTAATCTC
  TTACATAAGCATATTGAAGTTGCTAATGGCCCAGCCTCTCATTTTGAAACAAGACCTCAG
  ACATACGTGGATCATATGGATGGATCTTACTCACTTTCTGCCTTGCCATTTAGTCAGATG
  AGTGAGCTTCTGACTAGAGCTGAGGAAAGGGTATTAGTCAGACCACATGAACCACCTCCA
  CCTCCACCAATGCATGGAGCAGGAGATGCAAAACCGATACCCACCTGTATCAGTTCTGCT
  ACAGGTTTGATAGAAAATCGCCCTCAGTCACCAGCTACAGGCAGAACACCTGTGTTTGTG
  AGCCCCACTCCCCCACCTCCTCCACCACCTCTTCCATCTGCCTTGTCAACTTCCTCATTA
  AGAGCTTCAATGACTTCAACTCCTCCCCCTCCAGTACCTCCCCCACCTCCACCTCCAGCC
  ACTGCTTTGCAAGCTCCAGCAGTACCACCACCTCCAGCTCCTCTTCAGATTGCCCCTGGA
  GTTCTTCACCCAGCTCCTCCTCCAATTGCACCTCCTCTAGTACAGCCCTCTCCACCAGTA
  GCTAGAGCTGCCCCAGTATGTGAGACTGTACCAGTTCATCCACTCCCACAAGGTGAAGTT
  CAGGGGCTGCCTCCACCCCCACCACCGCCTCCTCTGCCTCCACCTGGCATTCGACCATCA
  TCACCTGTCACAGTTACAGCTCTTGCTCATCCTCCCTCTGGGCTACATCCAACTCCATCT
  ACTGCCCCAGGTCCCCATGTTCCATTAATGCCTCCATCTCCTCCATCACAAGTTATACCT
  GCTTCTGAGCCAAAGCGCCATCCATCAACCCTACCTGTAATCAGTGATGCCAGGAGTGTG
  CTACTGGAAGCAATACGAAAAGGTATTCAGCTACGCAAAGTAGAAGAGCAGCGTGAACAG
  GAAGCTAAGCATGAACGCATTGAAAACGATGTTGCCACCATCCTGTCTCGCCGTATTGCT
  GTTGAATATAGTGATTCGGAAGATGATTCAGAATTTGATGAAGTAGATTGGTTGGAGTAA
  
  Clone variation with respect to NM_003931.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003931 unedited
  NGGGTCGTTTTTGTATACGACTCCTATAGGCGGCCGCGNATTCGGCACGAGGCTAGCTTC
  GGTACTCTGACACCTTCTCTTGCACTTGCGGATGATGAACTGGAATAACGATGAAAGAAA
  GCACATCCGATCTCAACATTCACGTCCTGCCCTATAACCGATTAATTAATTGATCCCCAG
  CTAGACTAGTGTTGGAGAAATCAGCATGTTAAAACAACTGTTGATGATAGCTGTTGGAGT
  AAAGTTGCAGTGGAAGCTATGGCTGCAAAATCGTTAAAATCTTCAAGGTGAACTGGCACA
  AAGGTTAATCTCAAGATGCCGCTAGTGAAAAGAAACATCGATCCTAGGCACTTGTGCCAC
  ACAGCACTGCCTAGAGGCATTAAGAATGAACTGGAATGTGTAACCAATATTTCCTTGGCA
  AATATAATTAGACAACTAAGTAGCCTAAGTAAATATGCTGAAGATATATTTGGAGAATTA
  TTCAATGAAGCACATAGTTTTTCCTTCAGAGTCAACTCATTGCAAGAACGTGTGGACCGT
  TTATCTGTTAGTGTTACACAGCTTGATCCAAAGGAAGAAGAATTGTCTTTGCAAGATATA
  ACAATGAGGAAAGCTTTCCGAAGTTCTACAATTCAAGACCAGCAGCTTTTCGATCGCAAG
  ACTTTGCCTATTCCATTACAGGAGACGTACGATGTTTGTGAACAGCCTCCACCTCTCAAT
  ATACTCACTCCTTATAGAGATGATGGTAANAGAAGGTTCTGAAGTTNTATACCAATCCTT
  CGTATTTCTTTGATCTATGGAAAGAANNAATGTTGCAAGATACAGNAGGATAGAGGAAGG
  NAAAGAGGAAGCAGAAGCAGAAAATTCTAGATCGTCCTCATGAACCAGNANAAGTGCCAG
  AGCACCTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003931 unedited
  TGGACCGGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTAACTTTTAAAA
  TGAACCATTTATTAAATCAGACTGTTATTCTTAACAGTTATGTAAGTTACATGTATGTTT
  AAGTCAGAGTATTTCACATGGAAAAGTTTTTAACTCCTATAGGCAAGCAAAATCATATCA
  CACAATATATAAGTGGGAAGGGGATACTGCTAAACATTCAAATAAGGCAAGTATATAAAA
  ACAATAAAACAATAATGAAAAAATTCAAGCATTCCTTTAAGAGAATTCAACACTACAAGC
  TAAATGTACTTTCTGAGTGTATTCGTATAATCAAGGCAGTGTTTCTTCTTTTAAAACATC
  AGGAAATGGAATAAGGCTCATTAGTAGATACAGCTGCCCTCAAGATTTCAATTTCAGTTG
  CTTTCTTTAAATTAAAATTCACAAAGTACACAATTAAGATATATCAAAAAACTGAATCTG
  CTACTCTAACAACAGCTGTCCATGCTTAATACTTAGTGGTTTATTTGACCAAATTAGTCT
  TTTCAGGGGGAAAAAAAGATAAGCCACTGTAAAACATTCAGTTTGAAATGTATGCTAATA
  TTTTCCTTAAAAATCAAAAGTTATGGAGGAAAAGGGTCATTTATTATAAGGAAAAGAAAG
  CCAAACACTATAATGACCCAACATTTTCCAGGAACAAGCACCCCAAAGGACATTTGCATT
  CACCTTTGCAATATTATCAATGCCTTTTTCTTACTCCACCAATCTACTTCATCAAATTCT
  GAAACCTCTTCCGAAATACTATTTTCAACAGCTATACCGGTGAAACCAGGATGGTGGCCA
  CCATCGTCTCCAAAGGCCTCCATGCCTTACCTTCCTGTTCACCCTCGTTTTTTTATTTTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003931
• ORF Size: 1680 bp
• Insert Size: 2620
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003931.2, NP_003922.1
• RefSeq Size: 3230
• RefSeq ORF: 1680
• Locus ID: 8936
• Domains: WH2
• Protein Families: Druggable Genome
• Protein Pathways: Adherens junction, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton
• Gene Summary: The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longest transcript.