DcR1 (TNFRSF10C) (NM_003841) Human Untagged Clone

CAT#: SC117710

TNFRSF10C (untagged)-Human tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain (TNFRSF10C)


  "NM_003841" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol TNFRSF10C
Synonyms CD263; DCR1; DCR1-TNFR; LIT; TRAIL-R3; TRAILR3; TRID
Vector pCMV6-XL6
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_003841 edited
GAATTCGGCACGAGGAACCTCTCCACGCGCACGAACTCAGCCAACGATTTCTGATAGATT
TTTGGGAGTTTGACCAGAGATGCAAGGGGTGAAGGAGCGCTTCCTACCGTTAGGGAACTC
TGGGGACAGAGCGCCCCGGCCGCCTGATGGCCGAGGCAGGGTGCGACCCAGGACCCAGGA
CGGCGTCGGGAACCATACCATGGCCCGGATCCCCAAGACCCTAAAGTTCGTCGTCGTCAT
CGTCGCGGTCCTGCTGCCAGTCCTAGCTTACTCTGCCACCACTGCCCGGCAGGAGGAAGT
TCCCCAGCAGACAGTGGCCCCACAGCAACAGAGGCACAGCTTCAAGGGGGAGGAGTGTCC
AGCAGGATCTCATAGATCAGAACATACTGGAGCCTGTAACCCGTGCACAGAGGGTGTGGA
TTACACCAACGCTTCCAACAATGAACCTTCTTGCTTCCCATGTACAGTTTGTAAATCAGA
TCAAAAACATAAAAGTTCCTGCACCATGACCAGAGACACAGTGTGTCAGTGTAAAGAAGG
CACCTTCCGGAATGAAAACTCCCCAGAGATGTGCCGGAAGTGTAGCAGGTGCCCTAGTGG
GGAAGTCCAAGTCAGTAATTGTACGTCCTGGGATGATATCCAGTGTGTTGAAGAATTTGG
TGCCAATGCCACTGTGGAAACCCCAGCTGCTGAAGAGACAATGAACACCAGCCCGGGGAC
TCCTGCCCCAGCTGCTGAAGAGACAATGAACACCAGCCCAGGGACTCCTGCCCCAGCTGC
TGAAGAGACAATGACCACCAGCCCGGGGACTCCTGCCCCAGCTGCTGAAGAGACAATGAC
CACCAGCCCGGGGACTCCTGCCCCAGCTGCTGAAGAGACAATGACCACCAGCCCGGGGAC
TCCTGCCTCTTCTCATTACCTCTCATGCACCATCGTAGGGATCATAGTTCTAATTGTGCT
TCTGATTGTGTTTGTTTGAAAGACTTCACTGTGGAAGAAATTCCTTCCTTACCTGAAAGG
TTCAGGTAGGCGCTGGCTGAGGGCGGGGGGCGCTGGACACTCTCTGCCCTGCCTCCCTCT
GCTGTGTTCCCACAGACAGAAACGCCTGCCCCTGCCCCAAGTCCTGGTGTCTCCAGCCTG
GCTCTATCTTCCTCCTTGTGATCGTCCCATCCCCACATCCCGTGCACCCCCCAGGACCCT
GGTCTCATCAGTCCCTCTCCTGGAGCTGGGGGTCCACACATCTCCCAGCCAAGTCCAAGA
GGGCAGGGCCAGTTCCTCCCATCTTCAGGCCCAGCCAGGCAGGGGGCAGTCGGCTCCTCA
ACTGGGTGACAAGGGTGAGGATGAGAAGTGGTCACGGGATTTATTCAGCCTTGGTCAGAG
CAGAACACAGAGATTTTCCGTGTGTTGGTTTTTACTCTAGTTCCCCTTCTCATCCCCCTT
CCTCAGGGTGTCCCCTAATTGCAAGGCCCCATTCCTGTCCCCAGCCCCAGGGCTCCTTGT
CCAGTGTCCCAGCCCCCAGCCCAGCCCTGTGCCCCACTGTCCTCTGGGAGGGAGGTGCTG
CATGGGCCCCTCCCCACCTGCTAAGGAGACTCGTTCTCTTCCAAGTGGTGAAAGGGCCCC
TGAGCGTGTAGACAGAGTGACTTGGTTTCTCCAGAAACTGGAAGCCTCATGGGCTGAGGA
ACTGCCTCCCACCCACAGCAGAGCCCTGGCGGACACAATCCCTTTTCCTCATGGCTGCCC
TGACTCTCTGAAGTGGCTTGGGGTTCTGGGCTGACTGTGGGGGACACATGGCCATCTTGA
GCATCACACAGACCGGCGGGTCCTGCTGCAGTCCTGTCCTTCCTGTAGTCTTCACTCCAC
AGCCTCACTCCACAGTGAGTGACCCTCACTGGACACCCTCACTCCACAGCCTGCAACCTG
AGGATXXXXXXXXXXXXXXXXXXXXXXXXACTCCAGCCTGGGGGACAGAGCGAGACTCCA
TCTCAAACAACACACACACACACAAAACAACCAAAAAAAAAAAAAAAAAACTCGAC
>OriGene 5' read for NM_003841 unedited
CCCCGCCCCGTTGNCGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGA
GCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAAT
TCGGCACGAGGAACCTCTCCACGCGCACGAACTCAGCCAACGATTTCTGATAGATTTTTG
GGAGTTTGACCAGAGATGCAAGGGGTGAAGGAGCGCTTCCTACCGTTAGGGAACTCTGGG
GACAGAGCGCCCCGGCCGCCTGATGGCCGAGGCAGGGTGCGACCCAGGACCCAGGACGGC
GTCGGGAACCATACCATGGCCCGGATCCCCAAGACCCTAAAGTTCGTCGTCGTCATCGTC
GCGGTCCTGCTGCCAGTCCTAGCTTACTCTGCCACCACTGCCCGGCAGGAGGAAGTTCCC
CAGCAGACAGTGGCCCCACAGCAACAGAGGCACAGCTTCAAGGGGGAGGAGTGTCCAGCA
GGATCTCATAGATCAGAACATACTGGAGCCTGNTACCCGTGCACAGAGGGTGTGGATTAC
ACCAACGCTTCCAACATGAACCTTCTTGCTTCCATGTACAGTTTGTNAATCAGATCAAAA
CATANNAGTCCTGCCCATGACCAGAGACACAGTGTGTCAGTGTAAAGAAGCACCTTCCGG
ATGAAACTNCCANAATGTGCCGNAGTGTANNCAGTGCCTATGGGGAAGTCCAGTCAGTAA
TGTACGTCTGGGATGTATCCAGTGTGTGAAGATTTGTGCCATGCCATGGGAAAACCCACG
CTGAGAGACATGACACCAGCCGGGACTCTGCCCACTGCTGAAAACATGAACCCGCCAGGA
CTCTGGCCACTGCTGAAGACATGACACCANCCGGGACTCTGCCCAGTNTGAAAACATGAC
CCAGCCGGGGATCTGCCCACTGTGAAAAAT
>OriGene 3' read for NM_003841 unedited
GGGCTAGTTTTACTAGNACCGCGCCCTTCTANGATCGATTTTTTTTTTTTTTTTTTGGTT
GTTTTGTGTGTGTGTGTGTTGTTTGAGATGGAGTCTCGCTCTGTCCCCCAGGCTGGAGTG
CAGTGGCGCGATCGCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGC
CTCAGCCTCCCGAGTAGCTGGGATTACAGGCTTTCTTTTTTCTCGCCCGGCTAATTTTTT
GGGGCGGGGGGAGACACCGGGTTTCACCGTGTTATCCCGCCAGGATCCCACTCTTGTCCC
CTTTCGATCCCCCCATTTCCCCCTCTCAAATGCTGGAATTCCAGGCCCGGCCCCACCCCG
CCCCGCCCTGAAAATCTTTTTCTCTCCCTTTTTCCAACTGGCCACTTCCCTTTTTCCCTC
CCTCCTCCCACTGCCCCTCGACCCACCCTCCCCGTGACCCGTTGCACCCACATTTCCACA
TCCTTCAGCTTCCCCATCTCCTTTTTTAAATGTAATAATTACCTTATCTCCCTCCCCACA
CACCCCGCGTGCGTCGTCGCCTTCTTACTCCGGGGCGCCATCCTCGCACCCCGTCTATAC
CCGATACCCTCTGGGGGCGCAGCCGCATGCCCCGCGCAAATACCCCAATAATTAGATAAA
ACCTCGCCCGCGGCCCCCCCCCGCGGTCGCCCGCCGCGCCCCCCATCCGCGACCCGACCC
CGCCCGCCGCCTCGTTCCCTCCCACGTGACTAACCCCCAGGCACGCCCATTCCCGACCCA
ATACAACGCACTCGCCGCGCGGCGCGAGGTTAGCAGTATTATCGGCCCGCGCGGAGAAAC
CCGTCTCGTAGGTGTCCAAGCCGCCCGCTTCCT
Restriction Sites NotI-NotI     
ACCN NM_003841
ORF Size 780 bp
Insert Size 2800
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Reference Data
RefSeq NM_003841.2, NP_003832.2
RefSeq Size 1404
RefSeq ORF 780
Locus ID 8794
Domains TNFR
Protein Families Druggable Genome, Transmembrane
Protein Pathways Apoptosis, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity
Gene Summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]

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