TIF1 alpha (TRIM24) (NM_003852) Human Untagged Clone

CAT#: SC117716

TRIM24 (untagged)-Human tripartite motif containing 24 (TRIM24), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRIM24
• Synonyms: hTIF1; PTC6; RNF82; TF1A; TIF1; TIF1A; TIF1ALPHA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_003852 edited
  ATGGAGGTGGCGGTGGAGAAGGCGGTGGCGGCGGCGGCAGCGGCCTCGGCTGCGGCCTCC
  GGGGGGCCCTCGGCGGCGCCGAGCGGGGAGAACGAGGCCGAGAGTCGGCAGGGCCCGGAC
  TCGGAGCGCGGCGGCGAGGCGGCCCGGCTCAACCTGTTGGACACTTGCGCCGTGTGCCAC
  CAGAACATCCAGAGCCGGGCGCCCAAGCTGCTGCCCTGCCTGCACTCTTTCTGCCAGCGC
  TGCCTGCCCGCGCCCCAGCGCTACCTCATGCTGCCCGCGCCCATGCTGGGCTCGGCCGAG
  ACCCCGCCACCCGTCCCTGCCCCCGGCTCGCCGGTCAGCGGCTCGTCGCCGTTCGCCACC
  CAAGTTGGAGTCATTCGTTGCCCAGTTTGCAGCCAAGAATGTGCAGAGAGACACATCATA
  GATAACTTTTTTGTGAAGGACACTACTGAGGTTCCCAGCAGTACAGTAGAAAAGTCAAAT
  CAGGTATGTACAAGCTGTGAGGACAACGCAGAAGCCAATGGGTTTTGTGTAGAGTGTGTT
  GAATGGCTCTGCAAGACGTGTATCAGAGCTCATCAGAGGGTAAAGTTCACAAAAGACCAC
  ACTGTCAGACAGAAAGAGGAAGTATCTCCAGAGGCAGTTGGTGTCACCAGCCAGCGACCA
  GTGTTTTGTCCTTTTCATAAAAAGGAGCAGCTGAAGCTGTACTGTGAGACATGTGACAAA
  CTGACATGTCGAGACTGTCAGTTGTTAGAACATAAAGAGCATAGATACCAATTTATAGAA
  GAAGCTTTTCAGAATCAGAAAGTGATCATAGATACACTAATCACCAAACTGATGGAAAAA
  ACAAAATACATAAAATTCACAGGAAATCAGATCCAAAACAGAATTATTGAAGTAAATCAA
  AATCAAAAGCAGGTGGAACAGGATATTAAAGTTGCTATATTTACACTGATGGTAGAAATA
  AATAAAAGGAAAAGCTCTACTGCATCAGTTAGAGAGCCTTGCAAAGGACCATCGCATGAA
  ACTTATGCAACAACAACAGGAAGTGGCTGGACTCTCTAAACAATTGGAGCATGTCATGCA
  TTTTTCTAAATGGGCAGTTTCCAGTGGCAGCAGTACAGCATTACTTTATAGCAAACGACT
  GATTACATACCGGTTACGGCACCTCCTTCGTGCAAGGTGTGATGCATCCCCAGTGACCAA
  CAACACCATCCAATTTCACTGTGATCCTAGTTTCTGGGCTCAAAATATCATCAACTTAGG
  TTCTTTAGTAATCGAGGATAAAGAGAGCCAGCCACAAATGCCTAAGCAGAATCCTGTCGT
  GGAACAGAATTCACAGCCACCAAGTGGTTTATCATCAAACCAGTTATCCAAGTTCCCAAC
  ACAGATCAGCCTAGCTCAATTACGGCTCCAGCATATGCAGCAACAGGTAATGGCTCAGAG
  GCAACAGGTGCAACGGAGGCCAGCACCTGTGGGTTTACCAAACCCTAGAATGCAGGGGCC
  CATCCAGCAACCTTCCATCTCTCATCAGCAACCGCCTCCACGTTTGATAAACTTTCAGAA
  TCACAGCCCCAAACCCAATGGACCAGTTCTTCCTCCTCATCCTCAACAACTGAGATATCC
  ACCAAACCAGAACATACCACGACAAGCAATAAAGCCAAACCCCCTACAGATGGCTTTCTT
  GGCTCAACAAGCCATAAAACAGTGGCAGATCAGCAGTGGACAGGGAACCCCATCAACTAC
  CAACAGCACATCCTCTACTCCTTCCAGCCCCACGATTACTAGTGCAGCAGGATATGATGG
  AAAGGCTTTTGGTTCACCTATGATCGATTTGAGCTCACCAGTGGGAGGGTCTTATAATCT
  TCCCTCTCTTCCGGATATTGACTGTTCAAGTACTATTATGCTGGACAATATTGTGAGGAA
  AGATACTAATATAGATCATGGCCAGCCAAGACCACCCTCAAACAGAACGGTCCAGTCACC
  AAATTCATCAGTGCCATCTCCAGGCCTTGCAGGACCTGTTACTATGACTAGTGTACACCC
  CCCAATACGTTCACCTAGTGCCTCCAGCGTTGGAAGCCGAGGAAGCTCTGGCTCTTCCAG
  CAAACCAGCAGGAGCTGACTCTACACACAAAGTCCCAGTGGTCATGCTGGAGCCAATTCG
  AATAAAACAAGAAAACAGTGGACCACCGGAAAATTATGATTTCCCTGTTGTTATAGTGAA
  GCAAGAATCAGATGAAGAATCTAGGCCTCAAAATGCCAATTATCCAAGAAGCATACTCAC
  CTCCCTGCTCTTAAATAGCAGTCAGAGCTCTACTTCTGAGGAGACTGTGCTAAGATCAGA
  TGCCCCTGATAGTACAGGAGATCAACCTGGACTTCACCAGGACAATTCCTCAAATGGAAA
  GTCTGAATGGTTGGATCCTTCCCAGAAGTCACCTCTTCATGTTGGAGAGACAAGGAAAGA
  GGATGACCCCAATGAGGACTGGTGTGCAGTTTGTCAAAACGGAGGGGAACTCCTCTGCTG
  TGAAAAGTGCCCCAAAGTATTCCATCTTTCTTGTCATGTGCCCACATTGACAAATTTTCC
  AAGTGGAGAGTGGATTTGCACTTTCTGCCGAGACTTATCTAAACCAGAAGTTGAATATGA
  TTGTGATGCTCCCAGTCACAACTCAGAAAAAAAGAAAACTGAAGGCCTTGTTAAGTTAAC
  ACCTATAGATAAAAGGAAGTGTGAGCGCCTACTTTTATTTCTTTACTGCCATGAAATGAG
  CCTGGCTTTTCAAGACCCTGTTCCTCTAACTGTGCCTGATTATTACAAAATAATTAAAAA
  TCCAATGGATTTGTCAACCATCAAGAAAAGACTACAAGAAGATTATTCCATGTACTCAAA
  ACCTGAAGATTTTGTAGCTGATTTTAGATTGATCTTTCAAAACTGTGCTGAATTCAATGA
  GCCTGATTCAGAAGTAGCCAATGCTGGTATAAAACTTGAAAATTATTTTGAAGAACTTCT
  AAAGAACCTCTATCCAGAAAAAAGGTTTCCCAAACCAGAATTCAGGAATGAATCAGAAGA
  TAATAAATTTAGTGATGATTCAGATGATGACTTTGTACAGCCCCGGAAGAAACGCCTCAA
  AAGCATTGAAGAACGCCAGTTGCTTAAATAATATGCAGCACCACTAGCTTGTGCTGGTTT
  TTAGATTTTTTTGTTTTCAAAAAAACATTTGTCAGTAATTTAACATCACTACAAAAAGAA
  GAGTTTGTGACTATTCTCATCTCTGTTTTGGACGTTTACTAGACTTTGATTTCCTTAATA
  GCCCATTTCTGTTAACCTCTTATCACTAAGAAAGAAAGGAAAGAAGGAGATGAATAGAAG
  AAAGAAAATGGAAAGAAGGAAAAAAGGAGGATAGAAAAAGGATGGAAGAAAGAAGCATTG
  AAAACAAAGACATTCTTCCCACTTCTTGGATTTTTAAACCACAGTCTGGAGTGATAGCTA
  CTGTAGAAAGGAAATAGACTTTGTATGAACTCTTTAAGTTGAAAAGTAAAAAATATATGT
  GGTTTGGATGTGTGCTTTAATTCAGCTTTAGAAATTAATACCACTACCCGTGAATTATAT
  GGCCTGACAATATGAATTAGGTGTACTGTACTGAAGAACAGTACTCCACAAACATGGGTG
  GTAACAAGAGTTCCATCCCAGGAGGCCAAACGGTGCAACAGAAGGGTAGGTTAGATGCTA
  TTAAGAAGGCACTTAATAGTACATCATGTAAGATGGCAACTGTATTAAAGAAAAATCCGG
  AAAACAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTC
  CTGAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTGGA
  AGTTGCCACTCC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003852 unedited
  GGTTCAGATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGGTCGGGGGC
  GGCGGGCGNGAACCGCGCTCTCGCTTCCCCGGCGGCGGCAAGGGCAGGACAATGGAGGTG
  GCGGTGGAGAAGGCGGTGGCGGCGGCGGCAGCGGCCTCGGCTGCGGCCTCCGGGGGGCCC
  TCGGCGGCGCCGAGCGGGGAGAACGAGGCCGAGAGTCGGCAGGGCCCGGACTCGGAGCGC
  GGCGGCGAGGCGGCCCGGCTCAACCTGTTGGACACTTGCGCCGTGTGCCACCAGAACATC
  CAGAGCCGGGCGCCCAAGCTGCTGCCCTGCCTGCACTCTTTCTGCCAGCGCTGCCTGCCC
  GCGCCCCAGCGCTACCTCATGCTGCCCGCGCCCATGCTGGGCTCGGCCGAGACCCCGCCA
  CCCGTCCCTGCCCCCGGCTCGCCGGTCAGCGGCTCGTCGCCGTTCGCCACCCAAGTTGGA
  GTCATTCGTTGCCCAGTTTGCAGCCAAGAATGTGCAGAGAGACACATCATAGATAACTTT
  TTTGTGAAGGACACTACTGAGGTTCCCAGCAGTACAGTAGAAAAGTCAAATCAGGTATGT
  ACAAGCTGTGAGGACAACGCAGAAGCCAATGGGTTTTGTGTAGAGTGTGTTGAATGGCTC
  TGCAAGACGTGTATCAGAGCTCATCAGAGGGTAAAGTTCACAAAAGACCACACTGTCAGA
  CAGAAAGAGGAAGTATCTCCAGAGGCAGTTGGTGTCACCAGCCAGCGACCAGTGTTTTGT
  CCTTTTCATAAAAAGAGCAGCTGAAGCTGTACTGTGAGACATGTGACANACTGACATGTC
  GAGACTGTCAGTTGTTAGAACTANAGAGCTAGATACCAATTATAGAAGAGCTTTTCAGAT
  CAGNAAGTGATCTAGATC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003852 unedited
  ATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTTTTCCGGATTTTTCTTTAATACAGTTG
  CCATCTTACATGATGTACTATTAAGTGCCTTCTTAATAGCATCTAACCTACCCTTCTGTT
  GCACCGTTTGGCCTCCTGGGATGGAACTCTTGTTACCACCCATGTTTGTGGAGTACTGTT
  CTTCAGTACAGTACACCTAATTCATATTGTCAGGCCATATAATTCACGGGTAGTGGTATT
  AATTTCTAAAGCTGAATTAAAGCACACATCCAAACCACATATATTTTTTACTTTTCAACT
  TAAAGAGTTCATACAAAGTCTATTTCCTTTCTACAGTAGCTATCACTCCAGACTGTGGTT
  TAAAAATCCAAGAAGTGGGAAGAATGTCTTTGTTTTCAATGCTTCTTTCTTCCATCCTTT
  TTCTATCCTCCTTTTTTCCTTCTTTCCATTTTCTTTCTTCTATTCATCTCCTTCTTTCCT
  TTCTTTCTTAGNGATAAGAGGTTAACAGAAATGGGCTATTAAGGAAATCAAAGTCTAGTA
  AACGTCCAAAACAGAGATGAGAATAGTCACAAACTCTCCTTTTTGTAGCGATGTTAAATA
  CTGACAAATGTTTTTTTTTGAAACCAAAAAATCTANAACCAGCACAAGCCTAGTGGTGCT
  GCATATTATTTAAGCACCTGGCGTTTCTTCATGCTTTTGAGGCGTTTCTCCGGGGCTGTC
  CAAGTCTTATTCTGAACATCCCTAAATTCATTACCTTCTGATCATTCCTGAATTCTGGTT
  TGGAAAACCTTTTTTTTGAAAGAAGCTCTTTAAAAGATCCTTAAAAAATTTTAAATTTTA
  ATCCACATTGGCTATTTTGAGATAGGCTCATTGATTCCCCCCAGTTTGAAAGATCATTTA
  AAAAAACTACCAATTTTCAAGGTTTGAGTCCTGGGAAAATTTTCTTGGACTCTTTTTTAA
  TGTGTGACAAACCTGGGATCTTAATATTTGTAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003852
• ORF Size: 3051 bp
• Insert Size: 4110
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003852.3, NP_003843.3
• RefSeq Size: 3905
• RefSeq ORF: 3051
• Locus ID: 8805
• Domains: zf-B_box, BROMO, RING, PHD, BBC
• Protein Families: Druggable Genome, Protein Kinase, Transcription Factors
• Gene Summary: The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.