Neuropilin 1 (NRP1) (NM_003873) Human Untagged Clone

CAT#: SC117726

NRP1 (untagged)-Human neuropilin 1 (NRP1), transcript variant 1


  "NM_003873" in other vectors (6)

Reconstitution Protocol

USD 1,860.00

2 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol NRP1
Synonyms BDCA4; CD304; NP1; NRP; VEGF165R
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC117726 sequence for NM_003873 edited (data generated by NextGen Sequencing)
ATGGAGAGGGGGCTGCCGCTCCTCTGCGCCGTGCTCGCCCTCGTCCTCGCCCCGGCCGGC
GCTTTTCGCAACGATAAATGTGGCGATACTATAAAAATTGAAAGCCCCGGGTACCTTACA
TCTCCTGGTTATCCTCATTCTTATCACCCAAGTGAAAAATGCGAATGGCTGATTCAGGCT
CCGGACCCATACCAGAGAATTATGATCAACTTCAACCCTCACTTCGATTTGGAGGACAGA
GACTGCAAGTATGACTACGTGGAAGTCTTCGATGGAGAAAATGAAAATGGACATTTTAGG
GGAAAGTTCTGTGGAAAGATAGCCCCTCCTCCTGTTGTGTCTTCAGGGCCATTTCTTTTT
ATCAAATTTGTCTCTGACTACGAAACACATGGTGCAGGATTTTCCATACGTTATGAACTT
TTCAAGAGAGGTCCTGAATGTTCCCAGAACTACACAACACCTAGTGGAGTGATAAAGTCC
CCCGGATTCCCTGAAAAATATCCCAACAGCCTTGAATGCACTTATATTGTCTTTGCGCCA
AAGATGTCAGAGATTATCCTGGAATTTGAAAGCTTTGACCTGGAGCCTGACTCAAATCCT
CCAGGGGGGATGTTCTGTCGCTACGACCGGCTAGAAATCTGGGATGGATTCCCTGATGTT
GGCCCTCACATTGGGCGTTACTGTGGACAGAAAACACCAGGTCGAATCCGATCCTCATCG
GGCATTCTCTCCATGGTTTTTTACACCGACAGCGCGATAGCAAAAGAAGGTTTCTCAGCA
AACTACAGTGTCTTGCAGAGCAGTGTCTCAGAAGATTTCAAATGTATGGAAGCTCTGGGC
ATGGAATCAGGAGAAATTCATTCTGACCAGATCACAGCTTCTTCCCAGTATAGCACCAAC
TGGTCTGCAGAGCGCTCCCGCCTGAACTACCCTGAGAATGGGTGGACTCCCGGAGAGGAT
TCCTACCGAGAGTGGATACAGGTAGACTTGGGCCTTCTGCGCTTTGTCACGGCTGTCGGG
ACACAGGGCGCCATTTCAAAAGAAACCAAGAAGAAATATTATGTCAAGACTTACAAGATC
GACGTTAGCTCCAACGGGGAAGACTGGATCACCATAAAAGAAGGAAACAAACCTGTTCTC
TTTCAGGGAAACACCAACCCTACAGATGTTGTGGTTGCAGTATTCCCCAAACCACTGATA
ACTCGATTTGTCCGAATCAAGCCTGCAACTTGGGAAACTGGCATATCTATGAGATTTGAA
GTATATGGTTGCAAGATAACAGATTATCCTTGCTCTGGAATGTTGGGTATGGTGTCTGGA
CTTATTTCTGACTCCCAGATCACATCATCCAACCAAGGGGACAGAAACTGGATGCCTGAA
AACATCCGCCTGGTAACCAGTCGCTCTGGCTGGGCACTTCCACCCGCACCTCATTCCTAC
ATCAATGAGTGGCTCCAAATAGACCTGGGGGAGGAGAAGATCGTGAGGGGCATCATCATT
CAGGGTGGGAAGCACCGAGAGAACAAGGTGTTCATGAGGAAGTTCAAGATCGGGTACAGC
AACAACGGCTCGGACTGGAAGATGATCATGGATGACAGCAAACGCAAGGCGAAGTCTTTT
GAGGGCAACAACAACTATGATACACCTGAGCTGCGGACTTTTCCAGCTCTCTCCACGCGA
TTCATCAGGATCTACCCCGAGAGAGCCACTCATGGCGGACTGGGGCTCAGAATGGAGCTG
CTGGGCTGTGAAGTGGAAGCCCCTACAGCTGGACCGACCACTCCCAACGGGAACTTGGTG
GATGAATGTGATGACGACCAGGCCAACTGCCACAGTGGAACAGGTGATGACTTCCAGCTC
ACAGGTGGCACCACTGTGCTGGCCACAGAAAAGCCCACGGTCATAGACAGCACCATACAA
TCAGAGTTTCCAACATATGGTTTTAACTGTGAATTTGGCTGGGGCTCTCACAAGACCTTC
TGCCACTGGGAACATGACAATCACGTGCAGCTCAAGTGGAGTGTGTTGACCAGCAAGACG
GGACCCATTCAGGATCACACAGGAGATGGCAACTTCATCTATTCCCAAGCTGACGAAAAT
CAGAAGGGCAAAGTGGCTCGCCTGGTGAGCCCTGTGGTTTATTCCCAGAACTCTGCCCAC
TGCATGACCTTCTGGTATCACATGTCTGGGTCCCACGTCGGCACACTCAGGGTCAAACTG
CGCTACCAGAAGCCAGAGGAGTACGATCAGCTGGTCTGGATGGCCATTGGACACCAAGGT
GACCACTGGAAGGAAGGGCGTGTCTTGCTCCACAAGTCTCTGAAACTTTATCAGGTGATT
TTCGAGGGCGAAATCGGAAAAGGAAACCTTGGTGGGATTGCTGTGGATGACATTAGTATT
AATAACCACATTTCACAAGAAGATTGTGCAAAACCAGCAGACCTGGATAAAAAGAACCCA
GAAATTAAAATTGATGAAACAGGGAGCACGCCAGGATACGAAGGTGAAGGAGAAGGTGAC
AAGAACATCTCCAGGAAGCCAGGCAATGTGTTGAAGACCTTAGACCCCATCCTCATCACC
ATCATAGCCATGAGCGCCCTGGGGGTCCTCCTGGGGGCTGTCTGTGGGGTCGTGCTGTAC
TGTGCCTGTTGGCATAATGGGATGTCAGAAAGAAACTTGTCTGCCCTGGAGAACTATAAC
TTTGAACTTGTGGATGGTGTGAAGTTGAAAAAAGACAAACTGAATACACAGAGTACTTAT
TCGGAGGCATGA

Clone variation with respect to NM_003873.5
418 a=>c;1161 c=>t;1266 c=>t;2595 t=>c
>OriGene 5' read for NM_003873 unedited
CGGCACCAGGGGAAAAGGGAGAGGAAGCCGGAGCTAAATGACAGGATGCAGGCGACTTGA
GACACAAAAAGAGAAGCGTTCCTCTCGGATCCAGGCATTGCCTCGCTGCTTTCTTTTCTC
CAAGACGGGCTGAGGATTGTACAGCTCTAGGCGGAGTTGGGGCTCTTCGGATCGCTTAGA
TTCTCCTCTTTGCTGCATTTCCCCCCACGTCCTCGTTCTCCCGCGTCTGCCTGCGGACCC
GGAGAAGGGAGAATGGAGAGGGGGCTGCCGCTCCTCTGCGCCGTGCTCGCCCTCGTCCTC
GCCCCGGCCGGCGCTTTTCGCAACGATAAATGTGGCGATACTATAAAAATTGAAAGCCCC
GGGTACCTTACATCTCCTGGTTATCCTCATTCTTATCACCCAAGTGAAAAATGCGAATGG
CTGATTCAGGCTCCGGACCCATACCAGAGAATTATGATCAACTTCAACCCTCACTTCGAT
TTGGAGGACAGAGACTGCAAGTATGACTACGTGGAAGTCTTCGATGGAGAAAATGAANAT
GGACATTTTAGGGGAAAGTTCTGTGGAAAGATAGCCCCTCCTCCTGTTGTGTCTTCAGGG
CCATTTCTTTNTATCAAATTTGTCTCTGACTACGAAACACATGGTGCAGGATTTTCCATA
CGTTATGAACTTTTCAAGAGAGGTCCCTGATGTTCCCAGAACTACCACACACCTAGTGGA
GTGATAAAAGTCCCCGGATTCCCTGAAAATACCCNACAGCNCTGATGCACTATATTGCTT
TGCGCAAGA
>OriGene 3' read for NM_003873 unedited
GAACGCGGCACGCATCTATATCGAGTTTTTTTTTTTTTTTTTTTTACCAGTAAAATGAAA
ACATTTTACTACAGAAAGTTTTATAGATTTCCATAAAGAAAAAAATGTTATTTTACACCT
TTAAAAATTACAAAACAATCTAAAACAATATAAACTGAACATTTTGTAACACTGCCTTTA
CAAATTAATAACTTTATAAACATACAATTTTTAAATATATTTATCAGTGCAAGATACTTT
AAATTTTAAAGTTGCAGTATCATTTTTCCTTGGCTGAAGACAACTTTAAGTCTGTTGCCT
TTAAAAACAACAAACGAGTGTTTCTTATAGCTTTCCTTCTGGTAGGATTATATCAACTAA
ATGAATGTCTCTGGGGACAAAAAACTATTCTTCTTTCATGGAGATCAATATTTTCCTGGA
AACAAAAGGCATTCTCAATCCAATTTAACTAAGATGAATGGACTGTCTCATCTATGATGC
AAATGTGACTCCCAACAAATGTCTTTGAGTGAGACGTCTAGCAATGTGGGAAGGAAGATC
TAAAAAATCTCATGTCCAACATGGCATGATAAAAATCCACCAAAACCAACCAAAGCTTCT
TTGGGTTAATTCATAAGCTGCCTGNTAAGATATTAGCTTCCCTGTGCTGTTAGAAGCTTA
AATGCTGCCAGCCCTTAAAGCAGTCCTTATTTCTTTGTGAGCCGCTGGGAAGTTCTAGAA
ACACTCATTTAAGTCTATCTCTTCAAGCTTGCTGTTATGAATTTTAAAACATTTGTTTGA
CTTTATGAGTTTTCCCCCTCTTATCTAAAATACTGACCCCCAAGCTCAAGATTATAGCTT
CATTCCTAATTAACAGTCCTTCCTACACTCCCCTGTGGGAACTATTACAAAATAGAAAGT
TCTCTGAGCCTTTTTCATATTTGGAAGAAAAATCCAGCCTTTGGATTTGAAAATTATCCG
TTCTTCCTCGGCCCATTGAAACCATTAT
Restriction Sites NotI-NotI     
ACCN NM_003873
ORF Size 2772 bp
Insert Size 5480
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Reference Data
RefSeq NM_003873.3, NP_003864.3
RefSeq Size 5890
RefSeq ORF 2772
Locus ID 8829
Domains F5_F8_type_C, CUB, MAM
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Axon guidance
Gene Summary This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Transcript Variant: This variant (1) represents the longest transcript and it encodes the longest protein (isoform a).

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