NUMB (NM_003744) Human Untagged Clone

CAT#: SC117802

NUMB (untagged)-Human numb homolog (Drosophila) (NUMB), transcript variant 3


  "NM_003744" in other vectors (7)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol NUMB
Synonyms C14orf41; c14_5527; S171
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_003744, the custom clone sequence may differ by one or more nucleotides


ATGAACAAATTACGGCAAAGTTTTAGGAGAAAGAAGGATGTTTATGTTCCAGAGGCCAGTCGTCCACATC
AGTGGCAGACAGATGAAGAAGGCGTTCGCACCGGAAAATGTAGCTTCCCGGTTAAGTACCTTGGCCATGT
AGAAGTTGATGAATCAAGAGGAATGCACATCTGTGAAGATGCTGTAAAAAGATTGAAAGCTACTGGAAAG
AAAGCAGTTAAAGCAGTTCTGTGGGTCTCAGCAGATGGACTCAGAGTTGTGGATGAAAAAACTAAGGACC
TCATAGTTGACCAGACGATAGAGAAAGTTTCTTTCTGTGCCCCAGACAGGAACTTTGATAGAGCCTTTTC
TTACATATGCCGTGATGGCACCACTCGTCGCTGGATCTGTCACTGCTTCATGGCTGTCAAGGACACAGGT
GAAAGGTTGAGCCATGCAGTAGGCTGTGCTTTTGCAGCCTGTTTAGAGCGCAAGCAGAAGCGGGAGAAGG
AATGTGGAGTGACTGCTACTTTTGATGCTAGTCGGACCACTTTTACAAGAGAAGGATCATTCCGTGTCAC
AACAGCCACTGAACAAGCAGAAAGAGAGGAGATCATGAAACAAATGCAAGATGCCAAGAAAGCTGAAACA
GATAAGATAGTCGTTGGTTCATCAGTTGCCCCTGGCAACACTGCCCCATCCCCATCCTCTCCCACCTCTC
CTACTTCTGATGCCACGACCTCTCTGGAGATGAACAATCCTCATGCCATCCCACGCCGGCATGCTCCAAT
TGAACAGCTTGCTCGCCAAGGCTCTTTCCGAGGTTTTCCTGCTCTTAGCCAGAAGATGTCACCCTTTAAA
CGCCAACTATCCCTACGCATCAATGAGTTGCCTTCCACTATGCAGAGGAAGACTGATTTCCCCATTAAAA
ATGCAGTGCCAGAAGTAGAAGGGGAGGCAGAGAGCATCAGCTCCCTGTGCTCACAGATCACCAATGCCTT
CAGCACACCTGAGGACCCCTTCTCATCTGCTCCGATGACCAAACCAGTGACAGTGGTGGCACCACAATCT
CCTACCTTCCAAGCTAATGGCACTGACTCAGCCTTCCATGTGCTTGCTAAGCCAGCCCATACTGCTCTAG
CACCCGTAGCAATGCCTGTGCGTGAAACCAACCCTTGGGCCCATGCCCCTGATGCTGCTAACAAGGAAAT
TGCAGCCACATGTTCGGGGACCGAGTGGGGTCAATCTTCTGGTGCTGCCTCTCCAGGTCTCTTCCAGGCC
GGTCATAGACGTACTCCCTCTGAGGCCGACCGATGGTTAGAAGAGGTGTCTAAGAGCGTCCGGGCTCAGC
AGCCCCAGGCCTCAGCTGCTCCTCTGCAGCCAGTTCTCCAGCCTCCTCCACCCACTGCCATCTCCCAGCC
AGCATCACCTTTCCAAGGGAATGCATTCCTCACCTCTCAGCCTGTGCCAGTGGGTGTGGTCCCAGCCCTG
CAACCAGCCTTTGTCCCTGCCCAGTCCTATCCTGTGGCCAATGGAATGCCCTATCCAGCCCCTAATGTGC
CTGTGGTGGGCATCACTCCCTCCCAGATGGTGGCCAACGTATTTGGCACTGCAGGCCACCCTCAGGCTGC
CCATCCCCATCAGTCACCCAGCCTGGTCAGGCAGCAGACATTCCCTCACTACGAGGCAAGCAGTGCTACC
ACCAGTCCCTTCTTTAAGCCTCCTGCTCAGCACCTCAACGGTTCTGCAGCTTTCAATGGTGTAGATGATG
GCAGGTTGGCCTCAGCAGACAGGCATACAGAGGTTCCTACAGGCACCTGCCCAGTGGATCCTTTTGAAGC
CCAGTGGGCTGCATTAGAAAATAAGTCCAAGCAGCGTACTAATCCCTCCCCTACCAACCCTTTCTCCAGT
GACTTACAGAAGACGTTTGAAATTGAACTTTAA


>OriGene 5' read for NM_003744 unedited
TACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGATTACAGGTGTGAGCTACCAC
AACCAGCTAGTTTCTGTATTGTGGATGAGCCATAGCAACAGCGAGGGGTTTCTGACATCA
GTCAGCTGCCGTGGTTTAATGCATTTGAGCCATATCTAGACAGTGCTTCAGTGTGGCTGA
CACAGCAGCATGGTCTTGACAAGTTTTCTTCATCCTACCACAAAATCCCAGTTGGTAATA
GAGACTTTACTCCTACCTATCAAAACCACAAAATGTCCCATTAGGGGGGGACATGTTGTA
CATGTTAGGATCATTCAAATAACCAAGATTATAAGGTGAGGAAAGATGCCCCTAACTGAT
TCTTTTGTCTCTCATCTTGTTGGTTCCAGGGACCGAGTGGGGTCAATCTTCTGGTGCTGC
CTCTCCAGGTCTCTTCCAGGCCGGTCATAGACGTACTCCCTCTGAGGCCGACCGATGGTT
AGAAGAGGTGTCTAAGAGCGTCCGGGCTCAGCAGCCCCAGGCCTCAGCTGCTCCTCTGCA
GCCAGTTCTCCAGCCTCCTCCACCCACTGCCATCTCCCAGCCAGCATCACCTTTCCAAGG
GAATGCATTCCTCACCTCTCAGCCTGTGCCAGTGGGTGTGGTCCCAGCCCTGCACCAGCC
TTTGTCCCTGCCCAGTCCTATCCTGTGGCCAATGGAATGCCCTATCCAGCCCCTAATGTG
CCTGTGGTGGGCATCACTCCCTCCCAGATGGTGGCCAACGTATTTGGCACTGCAGGCCAC
CCTCANGCTGCCCCATCCCATCAGTCACCCAGCCTGGTCAGGCAGCAGACATTTCCTTCA
CTACGAGCAGCAGTGCTACCACCAGTCCTTTCTTTAAAGCTCTGCTCACACCTCAACGGT
TCTGCAGCTTTCATGGTGTAAAGATGGCAGGTTGGCTCACCGACAGCATACAGAGGTTCT
ACNG
>OriGene 3' read for NM_003744 unedited
GGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCTACCATGAACATTTATTTTTG
TTAAAGCAGATTATAAATTTTCATCAGTACAAATATATATAACTTACATTTGATTGTAAG
GCCAACGTTCAAAAGTAAAAATGAGATGAGCTCTCTTATTGTTATCCGAGGTCAAGAGGC
TGCAACTGTCAAGGGGATGTTCTCACCAAAAGGGGGTTTGGGGGAAGAGGACACACACAA
AGCTAATAAAACCAGAATCCCCATCCCCACAAAACTCATGGGAACAAAATTTAAAGGATA
AAACAAAACCCACCAAGACCCATATTACAAACCAATATGGTAACCTGTGTTCCCTTCTAT
GGTATGATTATGTCATGTTACCTTAGTGTTAAAAGATTAACATAAGGAAACTGCAGCAAT
ATATAAAAGATATATTCTCTATAGAGCATATTTCGATTGATTCCATTAAAATAATGACAT
TAGAATTCCATCATAGGTTTAAAACCAGGACAATACTGCTTTTCCTTTATTTAAAAAAAA
CTACAACCTAGTGACTGTATTGGTCATAAGCATGATTGTTGTTGCAATGTGCTACTTACA
ATGAATGACTGACAGAAAACAAGCTAGGGATCCTGTCTGCAGCTTCCAGCCTTTCCTCTT
TTTATTTCAGTAGGCATCAATGATAAATCAATCTTATGTACAATTTCTTACAACTAGCCC
CTTTACCTTNTGCANNGATACTTTACACTCATACAACTTNCTAATATCTGAGAACTATTT
AAATATTCTAAATGCATANAAATAAGATTTCGCCTTTTGAATATATAAATATTATTCCTG
TACTCAAAATGGAGCTCAACTCCNCCCCAAAATATCTCTGCTGGGCAGTGCTGATTGCCC
TCTAGGAATCTGCAGCTACGTCCTCTTGTCCCAGCTGACACAACATCTTCTGATTT
Restriction Sites NotI-NotI     
ACCN NM_003744
ORF Size 408 bp
Insert Size 2440
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_003744.1, NP_003735.1
RefSeq Size 3614
RefSeq ORF 408
Locus ID 8650
Domains PID
Protein Pathways Notch signaling pathway
Gene Summary The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 1.

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