Alkyl DHAP synthase (AGPS) (NM_003659) Human Untagged Clone

CAT#: SC117846

AGPS (untagged)-Human alkylglycerone phosphate synthase (AGPS)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AGPS
• Synonyms: ADAP-S; ADAS; ADHAPS; ADPS; ALDHPSY; RCDP3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117846 sequence for NM_003659 edited (data generated by NextGen Sequencing)
  ATGGCGGAGGCGGCGGCTGCAGCGGGNGGGACTGGNTTGGGCGCGGGCGCGAGCTACGGG
  TCTGCAGCGGACCGGGACCGGGACCCGGACCCGGACCGCGCCGGGCGGAGGCTGCGGGTT
  CTCTCTGGCCATCTGCTGGGCCGGCCCCGGGAGGCTCTGAGTACCAATGAGTGCAAAGCG
  CGGAGAGCCGCGTCGGCGGCCACGGCAGCGCCCACGGCCACTCCCGCCGCGCAGGAGTCG
  GGCACCATCCCAAAGAAGCGGCAAGAAGTTATGAAATGGAATGGATGGGGATATAATGAT
  TCTAAATTCATCTTCAATAAGAAGGGCCAAATTGAATTGACTGGGAAAAGGTACCCTCTT
  AGTGGCATGGGTTTACCAACATTTAAAGAATGGATCCAAAATACCCTTGGAGTAAATGTG
  GAGCATAAAACTACCTCTAAAGCATCCTTAAATCCTAGTGATACACCTCCTTCTGTTGTA
  AATGAAGATTTTCTTCATGACCTTAAAGAAACTAATATTTCATATTCACAAGAGGCAGAT
  GATCGAGTATTTAGAGCTCATGGTCATTGTCTTCATGAGATATTTTTGCTCAGGGAAGGA
  ATGTTTGAGCGAATTCCTGATATAGTTTTATGGCCAACATGCCATGATGATGTAGTTAAG
  ATTGTGAATCTAGCTTGCAAATATAATCTTTGTATCATACCAATTGGTGGAGGAACAAGT
  GTTTCATATGGCCTGATGTGTCCTGCAGATGAGACAAGAACAATTATTTCTTTGGACACT
  TCACAAATGAATCGAATTCTCTGGGTTGATGAGAACAATTTGACAGCTCATGTAGAGGCT
  GGCATAACAGGACAAGAGTTGGAAAGACAGCTTAAAGAAAGTGGTTATTGTACAGGTCAT
  GAACCAGATTCCCTGGAGTTCAGTACTGTAGGAGGATGGGTATCTACTCGCGCATCAGGC
  ATGAAGAAGAATATCTATGGCAATATCGAGGACCTGGTGGTTCATATAAAAATGGTAACA
  CCTAGAGGTATAATAGAAAAAAGCTGTCAAGGACCTCGTATGTCAACAGGCCCTGATATC
  CATCACTTCATCATGGGATCTGAAGGAACTCTTGGTGTAATAACAGAAGCTACAATAAAA
  ATCAGACCAGTCCCTGAATACCAAAAGTATGGCTCAGTAGCTTTCCCTAATTTTGAACAA
  GGAGTAGCCTGTTTAAGAGAAATTGCAAAACAGAGATGTGCTCCGGCATCTATTCGCCTC
  ATGGACAACAAGCAGTTTCAGTTTGGTCATGCTCTTAAACCTCAGGTTTCCTCTATTTTT
  ACATCATTTTTGGACGGATTAAAAAAGTTTTATATTACAAAGTTTAAAGGATTTGACCCA
  AATCAGCTAAGTGTAGCCACATTACTGTTTGAGGGGGATCGTGAGAAGGTTCTTCAACAT
  GAAAAACAAGTGTATGATATTGCTGCAAAATTTGGTGGGTTGGCAGCTGGAGAAGATAAT
  GGACAGAGAGGTTATTTGCTGACCTATGTTATTGCATACATTCGAGACTTGGCTTTGGAA
  TACTATGTATTAGGAGAATCTTTTGAGACTTCTGCTCCTTGGGACAGGGTGGTAGATCTC
  TGTAGAAATGTAAAAGAAAGAATAACAAGGGAATGCAAAGAGAAGGGTGTTCAGTTTGCT
  CCTTTTTCTACATGCAGGGTGACGCAGACTTACGATGCAGGTGCTTGTATCTACTTCTAT
  TTTGCCTTTAACTACAGGGGAATTAGTGACCCACTGACCGTATTTGAACAAACTGAGGCA
  GCTGCTAGAGAAGAAATCCTTGCTAATGGAGGGAGCCTGTCACATCACCATGGAGTGGGC
  AAGTTACGGAAGCAATGGCTAAAGGAAAGTATCTCTGATGTCGGCTTTGGGATGCTGAAG
  TCTGTCAAGGAATATGTGGACCCCAATAACATCTTTGGAAACAGAAACCTTTTATAA
  
  Clone variation with respect to NM_003659.3
  27 t=>n;36 c=>n
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003659 unedited
  GGGTCAAAATTTGTATACGACTCACTATAGGCGGCCGCGATTCGGCACGAGGCCGGGCGG
  CAGCACAAGGCGGTAGCCATGGCGGAGGCGGCGGCTGCAGCGGGTGGGACTGGCTTGGGC
  GCGGGCGCGAGCTACGGGTCTGCAGCGGACCGGGACCGGGACCCGGACCCGGACCGCGCC
  GGGCGGAGGCTGCGGGTTCTCTCTGGCCATCTGCTGGGCCGGCCCCGGGAGGCTCTGAGT
  ACCAATGAGTGCAAAGCGCGGAGAGCCGCGTCGGCGGCCACGGCAGCGCCCACGGCCACT
  CCCGCCGCGCAGGAGTCGGGCACCATCCCAAAGAAGCGGCAAGAAGTTATGAAATGGAAT
  GGATGGGGATATAATGATTCTAAATTCATCTTCAATAAGAAGGGCCAAATTGAATTGACT
  GGGAAAAGGTACCCTCTTAGTGGCATGGGTTTACCAACATTTAAAGAATGGATCCAAAAT
  ACCCTTGGAGTAAATGTGGAGCATAAAACTACCTCTAAAGCATCCTTAAATCCTAGTGAT
  ACACCTCCTTCTGTTGTAAATGAAGATTTTCTTCATGACCTTAAAGAAACTAATATTTCA
  TATTCACAAGAGGCAGATGATCGAGTATTTAGAGCTCATGGTCATTGTCTTCATGAGATA
  TTTTTGCTCAGGGAAGGAATGTTTGAGCGAATTCCTGATATAGTTTTATGGCCAACATGC
  CATGATGATGTAGTTAAGAATGGTGAATCTAGCTTGCAAATATAATCTTTGTATCATACC
  AATTGGTGGNAGGAACAGGTGTTTCATATGGCCTGATGTGTCCTGCAGATGAGACAGAAA
  CAATATTTCTTTTGGCACTTCACAAATGATCGATTCTCTGGGGTGATGAGAACAATTGAC
  AGCTCATGTAGAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003659 unedited
  GACCGCGGCACGCAATCTAGTGTCGAGNNNTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTATTTAAAACCAAAAAAACAAATGTATCCAAAATATAGTCCATGATATATTTGATTA
  CTAGTATAACCACAGTTGAAAACTTAAAAAAAAAATTGACATTTTTTTGTAATGGTACTA
  ATGGATTTATAAAAGGTTTCTGTTTCCAAAAATGTTATTGGGGTCCACATATTCCTTGAC
  AGACTTCAGCATCCCAAAGCCGACATCAAAAATACTTTCCTTTAACCATTGCTTCCGTAA
  CTTGCCCACTCCATGGGGATGTGACAGGCTCCCTCCATTAACAAGGATTTCTTCTCTAAC
  AGCTGCCTCAGTTTGTTCAAATACGGGCAGGGGGTCACTAATTCCCCTGTAGTTAAAGGC
  AAAATAAAAGTAGATACAAGCACCTGCATCGTAAGTCTGCGTCACCCTGCATGTAAAAAA
  AGGAGCAAACTGAACACCCTTCTCTTTGCATTCCCTTGGTATTCTTTCTTTTACATTTCT
  ACAGAGATCTACCACCCTGTCCCAAGGAGCAGAAGTCTCAAAAGATTCTCCTAATACATA
  GTATTCCAAAGCCAAGTCTCGAATGTATGCAATAACATAGGTCAGCAAATAACCTCTCTG
  TCCATTATCTTCTCCAGCTGCCAACCCACCAAATTTTGCAGCAATATCATACACTTGTTT
  TTCATGTTGAAGAACCTTCTCACGATCCCCCTCAAACAGTAATGTGGCTACACTTANCTG
  ATTNGGGNCAAATCCTTTTAAACTTGNAATATANAACTTTTCTAATCCGCCCAAAAATGA
  TGTANNAATAGAGAAACCCTGAGTTTATGACATGACCAACTGAACTGCTTGTTGTCATGA
  GCGAATANATGCCGAGCCATCTCTGTTTGCATTNTCTTAACAGCTACTCTTGTCAAATAT
  GGAAGCTCTGAGCATCCTTTGGTTCAGGATGGNCGATTTTATTGANCTCTGTATACACAA
  ATTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003659
• ORF Size: 1977 bp
• Insert Size: 2260
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003659.1, NP_003650.1
• RefSeq Size: 2074
• RefSeq ORF: 1977
• Locus ID: 8540
• Domains: FAD-oxidase_C, FAD_binding_4
• Protein Pathways: Ether lipid metabolism, Metabolic pathways
• Gene Summary: This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq, Jul 2008]