CUL4A (NM_003589) Human Untagged Clone

CAT#: SC117869

CUL4A (untagged)-Human cullin 4A (CUL4A), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CUL4A
• Synonyms: cullin 4A; OTTHUMP00000018753; OTTHUMP00000018754
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117869 sequence for NM_003589 edited (data generated by NextGen Sequencing)
  ATGCTCTACAAGCAACTGCGTCAGGCCTGTGAAGACCACGTCCAGGCACAGATCCTTCCG
  TTTAGAGAAGACTCACTAGATAGTGTTTTATTTTTAAAGAAGATTAACACGTGCTGGCAG
  GACCACTGCAGACAAATGATCATGATCAGAAGCATCTTCCTGTTCTTGGACCGCACCTAT
  GTGCTGCAGAACTCCACGCTGCCCTCCATCTGGGATATGGGATTAGAACTGTTTAGAACC
  CATATTATTAGTGATAAAATGGTTCAGAGTAAAACCATTGATGGAATCCTACTGCTGATC
  GAGCGCGAGAGGAGCGGCGAGGCCGTGGACCGGAGCCTGTTGCGGAGCCTCCTGGGCATG
  CTGTCTGACCTGCAGGTGTATAAAGATTCATTTGAACTGAAATTTTTGGAAGAGACTAAT
  TGCTTATATGCTGCCGAAGGCCAAAGGTTAATGCAGGAAAGAGAGGTTCCAGAATATCTT
  AACCATGTAAGTAAACGCTTAGAGGAAGAGGGAGACAGAGTAATCACTTACTTGGACCAC
  AGCACACAGAAACCACTGATTGCTTGTGTGGAGAAACAGCTATTAGGAGAACATTTAACA
  GCAATTCTGCAGAAAGGGCTCGACCACTTACTGGATGAGAACAGAGTGCCGGACCTCGCA
  CAGATGTACCAGCTGTTCAGCCGGGTGAGGGGCGGGCAGCAGGCGCTGCTGCAGCACTGG
  AGCGAGTACATCAAGACTTTTGGAACAGCGATCGTAATCAATCCTGAGAAAGATAAAGAC
  ATGGTCCAAGACCTGTTGGACTTCAAGGACAAGGTGGACCACGTGATCGAGGTCTGCTTC
  CAGAAGAATGAGCGGTTCGTCAACCTGATGAAGGAGTCCTTTGAGACGTTCATCAACAAG
  AGACCCAACAAGCCTGCAGAACTGATCGCAAAGCATGTGGATTCAAAGTTAAGAGCAGGC
  AACAAAGAAGCCACAGACGAGGAGCTGGAGCGGACGTTGGACAAGATCATGATCCTGTTC
  AGGTTTATCCACGGTAAAGATGTCTTTGAAGCATTTTATAAAAAAGATTTGGCAAAAAGA
  CTCCTTGTTGGGAAAAGTGCCTCAGTCGATGCTGAAAAGTCTATGTTGTCAAAGCTCAAG
  CATGAGTGCGGTGCAGCCTTCACCAGCAAGCTGGAAGGCATGTTCAAGGACATGGAGCTT
  TCGAAGGACATTATGGTTCATTTCAAGCAGCATATGCAGAATCAGAGTGACTCAGGCCCT
  ATAGACCTCACAGTGAACATACTCACAATGGGCTACTGGCCAACATACACGCCCATGGAA
  GTGCACTTAACCCCAGAAATGATTAAACTTCAGGAAGTATTTAAGGCATTTTATCTTGGA
  AAGCACAGTGGTCGAAAACTTCAGTGGCAAACTACTTTGGGACATGCTGTTTTAAAAGCG
  GAGTTTAAAGAAGGGAAGAAGGAATTCCAGGTGTCCCTCTTCCAGACACTGGTGCTCCTC
  ATGTTCAACGAGGGAGATGGCTTCAGCTTTGAGGAGATAAAAATGGCCACGGGGATAGAG
  GATAGTGAATTGCGCAGAACGCTGCAGTCCCTGGCCTGTGGCAAAGCACGTGTGCTGATT
  AAAAGTCCCAGAGGAAAGGAAGTGGAAGATGGAGACAAGTTCATTTTTAATGGAGAGTTC
  AAGCACAAGTTGTTTAGAATAAAGATCAATCAAATTCAGATGAAGGAAACTGTTGAGGAA
  CAGGTTAGCACCACTGAGAGAGTGTTTCAGGATAGACAATATCAGATTGATGCTGCTATC
  GTCAGAATAATGAAGATGAGAAAGACTCTTGGTCATAATCTTCTAGTTTCTGAATTATAT
  AATCAGCTGAAATTTCCAGTAAAGCCTGGAGATTTGAAAAAGAGAATTGAATCTCTGATA
  GACAGAGACTATATGGAGAGAGACAAAGACAATCCGAATCAGTACCACTACGTGGCCTGA
  
  Clone variation with respect to NM_003589.2
  774 c=>t;1212 c=>t;1631 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003589 unedited
  GTGTCACGTATATTTGTCAATACGCACTCCACTATAGGGGCTGGCCGCGCAATTCGGCAC
  GAGGCGGTTCCGGCCCAGCCATGGCGGACGAGGCCCCGCGGAAGGGCAGCTTCTCGGCGC
  TCGTGGGCCGCACCAACGGCCTCACCAAGCCCGCGGCCCTGGCCGCCGCGCCCGCCAAGC
  CGGGGGGCGCGGGCGGCTCCAAGAAGCTGGTCATCAAGAACTTCCGAGACAGACCTCGGC
  TGCCCGACAACTACACGCAGGACACGTGGCGGAAGCTGCACGAGGCGGTGCGGGCCGTGC
  AGAGCAGCACCTCCATCAGGTACAACCTCGAGGAGCTCTACCAGGCTGTGGAAAATCTCT
  GTTCTCACAAAGTCTCCCCAATGCTCTACAAGCAACTGCGTCAGGCCTGTGAAGACCACG
  TCCAGGCACAGATCCTTCCGTTTAGAGAAGACTCACTAGATAGTGTTTTATTTTTAAAGA
  AGATTAACACGTGCTGGCAGGACCACTGCAGACAAATGATCATGATCAGAAGCATCTTCC
  TGTTCTTGGACCGCACCTATGTGCTGCAGAACTCCACGCTGCCCTCCATCTGGGATATGG
  GATTAGAACTGTTTAGAACCCATATTATTAGTGATAAAATGGTTCAGAGTAACACCATTG
  ATGGAATCCTACTGCTGATCGAGCGCGACAGGAGCGGCCAGCCCGTGGACCGGAACCTGT
  TGCGGAGCCTCCTGGGCATGCTGTCTGACCCTGCATGTGTATAAAGAACCATTCTGAACT
  GAAAATTTTTGGCACGAGACCTAATGCTTTATATGCTGCCCGAAGGCCAAAGTTTAATGC
  AGGAAANAGAGGTTCCCGCAAAACTTAACCATGTTAGTAACCGCTTACAGCAAGAGGGGA
  ACCGAGTAATACTTACCTGGCCCCCAGCCCCCAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003589 unedited
  GTCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAATTTTAAGGCCAATT
  AAACTAATTTTATTCAAAGTAAGTCTACATTAAATTACAATATTAACAATCTCTAGACAC
  AACGAACTTATAAGAAAAAAAAATAGAAATCTGTTTGGTCTTTCTTAGACCACATATCAT
  GGAACTCATAAATGAAAATTTTCAAAGATAGAAATGACAATTAAAGAGTGAGGATTTTAA
  TATGGAAACCCACAAGGTGTCATATTTCAAACCCGCATGTTTCAAAAAGAGACTCTTAAT
  AATTTAGCACAAAATCAAATTATATAAACTTGGTATATTCCAGAAAATATTGCTTTAAAC
  ACTTATGCCATGATCAAAATTCCTTTGGTAGCTTTTAATCAAAATGAAACATGCTATTAT
  GTAAAATATAAAGTACTTTTAAATGTTATCTCAAAAGTATCTTTGTCATAGTTACCCTTC
  TAACATCACTACTGAACTTTCCTTTCACTGTTCAACCTCATGTATATATACACAACACAA
  AACCAGGTACCAACAAAATCCTTTTAATCTTTCCACAAAATAACCTCTGCTTCACAACAT
  CAAGACTTTAAGTCTCCATAAACTTTTTACAGTTTACAGCAGAGAACAAGGATCGTCCCT
  GCGCATGACTGTAAAAACCAAACCAAACTTTATTATTGCAATCACACAAATACTGCAATT
  AAAAAAAATCAAAGAGCAGTTACCCCAATGCAAAAAACAGGGACTGCCAGACTCAATCTT
  AGAATGGAAACANCAACACACTAGCCCCCAACCCCTAAACAGAGATTACAAGGAACTCAN
  CTGACGAACAGACGCAGCAGGGCNGACACCATGGCCTTGGGCACTCAGGNAGCTCACTTA
  GAAACCCTGACTACGAAAAATCACCATCAAAGTTTACAACTTTTGAANTACATN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003589
• ORF Size: 1980 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003589.2, NP_003580.1
• RefSeq Size: 3735
• RefSeq ORF: 1980
• Locus ID: 8451
• Domains: CULLIN
• Protein Pathways: Nucleotide excision repair, Ubiquitin mediated proteolysis
• Gene Summary: CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al., 2009 [PubMed 19481525]). [supplied by OMIM, Oct 2009]
  Transcript Variant: This variant (2) utilizes an alternate 5' terminal exon, compared to variant 1, resulting in an isoform (2) with a shorter N-terminus. Variants 2, 3, 5, 6, and 7 all encode the same isoform (2). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.