SPOP (NM_003563) Human Untagged Clone

CAT#: SC117899

SPOP (untagged)-Human speckle-type POZ protein (SPOP), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SPOP
• Synonyms: BTBD32; TEF2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003563 edited
  GAATTCGGCACGAGGCGCGCTCCGAGTGTGTGTGTATTTGTGTATCGGCGGTCCCGCAGG
  TCCCGGATGTTGCGGACAGTATGAGGCAAGCGCAGGGGGACGGGGACCAGCAGCTGTCGC
  CGCCGCTCTCAGATCGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCGATCTC
  GGCTCACTGCCACCTTTGCCTCCTGGGTTCAAGCGATTCTTCTGCCTCAGCCTCCCGAGT
  AGCTGGGATTACAGGGTGAAGAGGGAACAGAAATCTTTGCCCCCTGACTTTGGAAATCTC
  GTTTAACCTTCAAACTGGCGATGTCAAGGGTTCCAAGTCCTCCACCTCCGGCAGAAATGT
  CGAGTGGCCCCGTAGCTGAGAGTTGGTGCTACACACAGATCAAGGTAGTGAAATTCTCCT
  ACATGTGGACCATCAATAACTTTAGCTTTTGCCGGGAGGAAATGGGTGAAGTCATTAAAA
  GTTCTACATTTTCATCAGGAGCAAATGATAAACTGAAATGGTGTTTGCGAGTAAACCCCA
  AAGGGTTAGATGAAGAAAGCAAAGATTACCTGTCACTTTACCTGTTACTGGTCAGCTGTC
  CAAAGAGTGAAGTTCGGGCAAAATTCAAATTCTCCATCCTGAATGCCAAGGGAGAAGAAA
  CCAAAGCTATGGAGAGTCAACGGGCATATAGGTTTGTGCAAGGCAAAGACTGGGGATTCA
  AGAAATTCATCCGTAGAGATTTTCTTTTGGATGAGGCCAACGGGCTTCTCCCTGATGACA
  AGCTTACCCTCTTCTGCGAGGTGAGTGTTGTGCAAGATTCTGTCAACATTTCTGGCCAGA
  ATACCATGAACATGGTAAAGGTTCCTGAGTGCCGGCTGGCAGATGAGTTAGGAGGACTGT
  GGGAGAATTCCCGGTTCACAGACTGCTGCTTGTGTGTTGCCGGCCAGGAATTCCAGGCTC
  ACAAGGCTATCTTAGCAGCTCGTTCTCCGGTTTTTAGTGCCATGTTTGAACATGAAATGG
  AGGAGAGCAAAAAGAATCGAGTTGAAATCAATGATGTGGAGCCTGAAGTTTTTAAGGAAA
  TGATGTGCTTCATTTACACGGGGAAGGCTCCAAACCTCGACAAAATGGCTGATGATTTGC
  TGGCAGCTGCTGACAAGTATGCCCTGGAGCGCTTAAAGGTCATGTGTGAGGATGCCCTCT
  GCAGTAACCTGTCCGTGGAGAACGCTGCAGAAATTCTCATCCTGGCCGACCTCCACAGTG
  CAGATCAGTTGAAAACTCAGGCAGTGGATTTCATCAACTATCATGCTTCGGATGTCTTGG
  AGACCTCTGGGTGGAAGTCAATGGTGGTGTCACATCCCCACTTGGTGGCTGAGGCATACC
  GCTCTCTGGCTTCAGCACAGTGCCCTTTTCTGGGACCCCCACGCAAACGCCTGAAGCAAT
  CCTAAGATCCTGCTTGTTGTAAGACTCCGTTTAATTTCCAGAAGCAGCAGCCACTGTTGC
  TGCCACTGACCACCAGGTAGACAGCGCAATCTGTGGAGCTTTTACTCTGTTGTGAGGGGA
  AGAGACTGCATTGTGGCCCCAGACTTTTAAAACAGCACTAAATAACTTGGGGGAAACGGG
  GGGAGGGAAAATGAAATGAAAACCCTGTTGCTGCGTCACTGTGTTCCCTTTGGCCTGGCT
  GAGTTTGATACTGTGGGGATTCAGTTTAGGCGCTGGCCCGAGGATATCCCAGCGGTGGTA
  CTTCGGAGACACCTGTCTGCATCTGACTGAGCAGAACAAATCGTCAGGTGCCTGGAGCAA
  AAAGGAAAAAAAAAAAAGAAAGGACATTGAGTTTTAACAGAAGGGAAAAGGAAAGAAGAA
  AAGATTTTTGCAGAATTTCTCAAAAATCAGTTTGTGGATTCCAGTAGTATTTATATTGAG
  AGAAACAAATTTTAGTCCTTCTAACTGTGCTAAAACTTGGATATTTGTGAAAACTCCTTA
  CCACCATACAAGCATCAGAAGAGCTCTCTTGTTGTTAGCACTTATTGTTTGCAAGAACAG
  AATACATCCTTTTATCCTTTTATGAAAAATGACAAGTGAAGGCAAAAGGGGAAGGTTATT
  TGATCTGGAAGATGAGTGTTCTGATGTGGTGGCTTTTGCAAAAATCTTTATTGGTGTTGA
  AAACTGGAAAAAATAACTCATCCAGAATTCATATTGTCTTGACAAGAACTATGGTTCTCT
  GTTTTTAGATATTGTGGAAAATGTTTTTGGGCATTTTTCTCTGATTTTATTTCTTCTCCC
  CCACCCCTTTTTCTAAAAAACAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003563 unedited
  NGGGTCGAATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGGCGCGCTCC
  GAGTGTGTGTGTATTTGTGTATCGGCGGTCCCGCAGGTCCCGGATGTTGCGGACAGTATG
  AGGCAAGCGCAGGGGGACGGGGACCAGCAGCTGTCGCCGCCGCTCTCAGATCGAGTCTTG
  CTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCCACCTTTGCCTCC
  TGGGTTCAAGCGATTCTTCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGGTGAAGAG
  GGAACAGAAATCTTTGCCCCCTGACTTTGGAAATCTCGTTTAACCTTCAAACTGGCGATG
  TCAAGGGTTCCAAGTCCTCCACCTCCGGCAGAAATGTCGAGTGGCCCCGTAGCTGAGAGT
  TGGTGCTACACACAGATCAAGGTAGTGAAATTCTCCTACATGTGGACCATCAATAACTTT
  AGCTTTTGCCGGGAGGAAATGGGTGAAGTCATTAAAAGTTCTACATTTTCATCAGGAGCA
  AATGATAAACTGAAATGGTGTTTGCGAGTAAACCCCAAAGGGTTAGATGAAGAAAGCAAA
  GATTACCTGTCACTTTACCTGTTACTGGTCAGCTGTCCAAAGAGTGAAGTTCGGGCAAAA
  TTCAAATTCTCCATCCTGAATGCCAAGGGAGAAGAAACCAAAGCTATGGAGAGTCAACGG
  GCATATAGGGTTTGTGCAAGGCAAAGACTGGGGATTCAAGAAATTCATCCGTAGAGATTN
  TCTTTTTGGATGAGGCCAACGGGCTTCTCCCTGATGACAAGCTTACCCTCTCTGCGAGGG
  NGAAGTGTTGTGCAAGATTCTGTCACCATTTCTGGGCAGAATACATGACTGNGNGNAAGG
  TTCCCTGAGTGCCGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003563 unedited
  CGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGTTTTTAAAAAAGGGGTG
  GGGGAGAAGAAATAAAATCGAGAAAATGCCCAAAAACATTTTCCCAATATCTAAAAACAG
  AGAACCATAGTTCTTGTCAAGACAATATGAATTCTGGATGAGTTATTTTTTCCAGTTTTC
  AACACCAATAAAGATTTTTGCAAAAGCCACCACATCAGAACACTCATCTTCCAGATCAAA
  TAACCTTCCCCTTTTGCCTTCACTTGTCATTTTTCATAAAAGGATAAAAGGATGTATTCT
  GTTCTTGCAAACAATAAGTGCTAACAACAAGAGAGCTCTTCTGATGCTTGTATGGTGGTA
  AGGAGTTTTCACAAATATCCAAGTTTTAGCACAGTTAGAAGGACTAAAATTTGTTTCTCT
  CAATATAAATACTACTGGAATCCACAAACTGATTTTTGAGAAATTCTGCAAAAATCTTTT
  CTTCTTTCCTTTTCCCTTCTGTTAAAACTCAATGTCCTTTCTTTTTTTTTTTTCCTTTTT
  GCTCCAGGCACCTGACGATTTGTTCTGCTCAGTCAGATGCAGACAGGTGTCTCCGAAGTA
  CCACCGCTGGGATATCCTCGGGCCAGCGCCTAAACTGAATCCCCACAGTATCAAACTCAG
  CCAGGCCAAAGGGAACACAGTGACGCAGCAACAGGGTTTTCATTTCATTTTCCCTCCCCC
  GTTTCCCCCCAGTTATTTAGTGCTGTTTTAAAAGTCTGGGGCCACAATGCAGTCTCTTCC
  CCTCACACAGAGTAAAAGCTCCACAGATGCGCTGTCTACCTGGTGGTCAGTGGCAGCACA
  GTGGCTGCTGCTTCTGGAANTAAACGGAGTCTTACANNCAGCAGATCTTANGGATGCTCA
  GGCGTTGCGTGGGGGGTCCANAAAGGCACTGTGCTGAACCANNAAGCGGATGCCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003563
• ORF Size: 1125 bp
• Insert Size: 2430
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003563.3, NP_003554.1
• RefSeq Size: 3053
• RefSeq ORF: 1125
• Locus ID: 8405
• Domains: BTB, MATH
• Gene Summary: This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Transcript variants 1-6 encode the same protein.