MAD1 (MAD1L1) (NM_003550) Human Untagged Clone

CAT#: SC117934

MAD1L1 (untagged)-Human MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MAD1L1
• Synonyms: MAD1; PIG9; TP53I9; TXBP181
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117934 sequence for NM_003550 edited (data generated by NextGen Sequencing)
  ATGGAAGACCTGGGGGAAAACACCATGGTTTTATCCACCCTGAGATCTTTGAACAACTTC
  ATCTCTCAGCGTGTGGAGGGAGGCTCTGGACTGGATATTTCTACCTCGGCCCCAGGTTCT
  CTGCAGATGCAGTACCAGCAGAGCATGCAGCTGGAGGAAAGAGCAGAGCAGATCCGTTCG
  AAGTCCCACCTCATCCAGGTGGAGCGGGAGAAAATGCAGATGGAGCTGAGTCACAAGAGG
  GCTCGAGTGGAGCTGGAGAGAGCAGCCAGCACCAGTGCCAGGAACTACGAGCGTGAGGTC
  GACCGCAACCAGGAGCTCCTGACGCGCATCCGGCAGCTTCAGGAGCGGGAGGCCGGGGCG
  GAGGAGAAGATGCAGGAGCAGCTGGAGCGCAACAGGCAGTGTCAGCAGAACTTGGATGCT
  GCCAGCAAGAGGCTGCGTGAGAAAGAGGACAGTCTGGCCCAGGCTGGCGAGACCATCAAC
  GCACTGAAGGGGAGGATCTCGGAACTGCAGTGGAGCGTGATGGACCAGGAGATGCGGGTG
  AAGCGCCTGGAGTCGGAGAAGCAGGAGCTGCAGGAGCAGCTGGACCTGCAACACAAAAAA
  TGCCAGGAAGCCAATCAGAAAATCCAGGAACTCCAGGCCAGCCAAGAAGCAAGAGCAGAC
  CATGAGCAGCAGATTAAGGATCTGGAGCAGAAGCTGTCCCTGCAAGAGCAGGATGCAGCG
  ATTGTGAAGAACATGAAGTCTGAGCTGGTACGGCTCCCTAGGCTGGAACGGGAGCTGAAG
  CAGCTGCGGGAGGAGAGCGCGCACCTGCGGGAGATGAGAGAGACCAACGGGCTGCTCCAG
  GAAGAGCTGGAAGGGCTGCAGAGGAAGCTGGGGCGCCAGGAGAAGATGCAGGAGACGCTG
  GTTGGCTTGGAGCTGGAGAACGAGAGGCTGCTGGCCAAGCTGCAAAGCTGGGAGAGACTG
  GACCAGACCATGGGCCTGAGCATCAGGACTCCAGAAGACCTTTCCAGATTCGTGGTTGAG
  CTGCAGCAGAGGGAGCTTGCCTTGAAGGACAAGAACAGCGCCGTCACCAGCAGCGCCCGG
  GGGCTGGAGAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTG
  TTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGGAGGCTCCAGAAACGG
  GTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGC
  GAGCTGACCCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGAT
  ATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAGCTGTCGCAGGCCCTG
  GAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTG
  AAGTCTCAGTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACG
  CTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTGGAGGAGGAAAAGAGG
  ATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACC
  AAAGTGCTGCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCACGAGGAC
  CACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTGCGCGCCATGGAGAGA
  GGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAG
  GTGGCAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAG
  GTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAG
  ATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGC
  GACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACA
  GAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATC
  CCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAG
  
  Clone variation with respect to NM_003550.2
  663 c=>t;1673 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003550 unedited
  GTGTTAGAATTGTATACGACTCATATAGGCGGCCGCGAAATTCGCACGAGGGCGGCGGCA
  AGCTGGCTGCGAGCGGCTGAGCAGCACTCCAAGCTCGCCGGCCTTTGGTCTCCAGGACTT
  GTCCCAGCAGCCCCTCGAACTGAGAATTACACCATCGGACCCCTGGCTCTGAGGCCTTCA
  GACTTGGACTGTGTCACACTGCCAGGCTTCCAGGGCTCCAACTTGCAGACGGCCTGTTGT
  GGGACAGTCTCTGTAATCGCGAAAGCAACCATGGAAGACCTGGGGGAAAACACCATGGTT
  TTATCCACCCTGAGATCTTTGAACAACTTCATCTCTCAGCGTGTGGAGGGAGGCTCTGGA
  CTGGATATTTCTACCTCGGCCCCAGGTTCTCTGCAGATGCAGTACCAGCAGAGCATGCAG
  CTGGAGGAAAGAGCAGAGCAGATCCGTTCGAAGTCCCACCTCATCCAGGTGGAGCGGGAG
  AAAATGCAGATGGAGCTGAGTCACAAGAGGGCTCGAGTGGAGCTGGAGAGAGCAGCCAGC
  ACCAGTGCCAGGAACTACGAGCGTGAGGTCGACCGCAACCAGGAGCTCCTGACGCGCATC
  CGGCAGCTTCAGGAGCGGGAGGCCGGGGCGGAGGAGAAGATGCAGGAGCAGCTGGAGCGC
  AACAGGCCGTGTCAGCAGAACTTGGATGCTGCCAGCAAGAGGCTGCGTGAGACAGAAGAC
  AGTCTGGCCCAGGCTGTCGAGACCATCAACGCACTGAANGGNAGGATCTCGGAACTGCAG
  TGCAACGTGATGGACCACGAGATGCGGGTGAAACGCCTGAAGTCGGAGAAGCAGAGCTGC
  AAGAGCANCTGAACCTGCAACACAAAAAAGCCAGGAACCCATTCAGAAATCCAGNACCTC
  CG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003550 unedited
  GGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTCTAGGGGAGAAGATTTTATT
  TCACAAGGTGAGGAACCCAGGCTGGTGGCCGACGCCCACACACCAGGCTCCGGGACGCAT
  GGGGTCTGCACGTGGAGAGGGTGCTGGCCGCCCCAGCAGGAAGCCCGACGTAGGTCCCAG
  CGTGTCTGTCAGTCATGCTGCTGCCCTGTGGGGCTGGAGAGGCAGGACGTGCACCCAGCC
  TGTGGCTGGCGGGGCAGGGGACCTGCAGGTCAGGCCAAGCAGAGTGGCTCCGGCTATGCC
  CCCGAGCCTGCAGGCTACGCCACGGTCTGGCGGCTGAAGAGCTCGAGGGTGAGCGAGCTG
  AGGAAGGCAGGGATGCTGTCCTGGCGCCGCAGGTGCACCTCGATGAGCTCGCCCACGGTG
  TGTGAGAACTCTGTCTCCAGTAGCTGCATCTTGGAACCCGAGGGGCTGGTGGCCTTGAAG
  ATGAGGCAGTCGCCTGGGTGCTCGGCGTACAGCGAGGTCAGCCGGTACTGGTTCTCCGTG
  GTGATGTCGATCTGGTAGCCCGTGAGCGTGTAGCAGGCCTTGCCGAACTNCTGGATCTTG
  GTCTGGNAAACCTCCCTGAGCCGCTGTTNTTCAGCTCGGCACTCTTCACCTGCTTNTTCA
  GCTCTGCCACCTCCCGGNACGATGGCAGACTCGCGCCGGCAGCCTCAGGTCNGCTGGGAC
  GGTGCCTCCCTCTTCATGGCGCGCAGGACCCGCGCAGTCGCTCGCACTCCGCCTGAACTG
  CCTGTGGCCTCGTGCAGCCCCTGCTGGCACCCTGGTGGGGTTCAAGCTCATGGGCCCCAC
  TTTTGGCCCTGCCTGGGCATAGCAACCCTGCAGAGCTTGCGTTCACCTGTGCCTTCAGAT
  CTTTTTTCTTCTCCAGCGATCCGGTGGCTTCAAGTTCTGACTTAACTGAGGGGGCCGCTC
  TCCTGAAAACNGAACTTGTTCGGCAACTGGCTGAACTAAAACTTACCCCATCTCAAAGCT
  GGTCTTGTTCG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003550
• ORF Size: 2157 bp
• Insert Size: 3000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003550.2, NP_003541.2
• RefSeq Size: 2754
• RefSeq ORF: 2157
• Locus ID: 8379
• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle
• Gene Summary: MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1-4 encode the same isoform.