ACOX2 (NM_003500) Human Untagged Clone

CAT#: SC117937

ACOX2 (untagged)-Human acyl-CoA oxidase 2, branched chain (ACOX2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ACOX2
• Synonyms: BCOX; BRCACOX; BRCOX; CBAS6; THCCox
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117937 sequence for NM_003500 edited (data generated by NextGen Sequencing)
  ATGGGCAGCCCAGTGCACCGATTGTCATTGGGGGATACCTGGAGCAGGCAAATGCACCCC
  GACATAGAGAGCGAGAGGTATATGCAGTCCTTTGACGTGGAACGGCTCACCAACATCCTT
  GATGGAGGTGCCCAGAACACTGCACTCCGCAGGAAAGTTGAGAGCATCATCCACAGTTAC
  CCGGAGTTTAGCTGTAAGGACAATTATTTCATGACCCAGAATGAGCGTTATAAGGCTGCC
  ATGCGGAGGGCATTCCACATCCGGTTGATAGCTCGGCGCCTGGGTTGGTTAGAAGATGGT
  CGTGAATTAGGCTACGCTTACAGAGCCCTTTCTGGAGACGTGGCCTTAAATATACACAGA
  GTCTTCGTGAGAGCCCTCAGGAGCCTGGGCTCAGAGGAGCAGATTGCCAAATGGGACCCA
  CTCTGCAAAAACATCCAGATCATCGCAACGTATGCACAGACAGAGTTGGGACATGGGACA
  TATCTTCAGGGCCTGGAGACTGAAGCCACCTATGACGCAGCCACCCAGGAGTTTGTGATA
  CACAGCCCCACGCTGACTGCCACCAAATGGTGGCCTGGAGACTTGGGACGGTCAGCCACC
  CATGCCCTGGTCCAGGCCCAGCTGATCTGCTCAGGAGCCAGGCGGGGCATGCACGCTTTT
  ATTGTGCCAATCCGGAGTCTTCAGGACCACACCCCACTGCCAGGAATCATCATTGGGGAC
  ATCGGACCCAAGATGGACTTTGATCAAACAGACAATGGCTTCCTGCAGCTGAACCATGTG
  CGGGTCCCCAGGGAGAACATGCTGAGTCGCTTTGCACNGGTCTTGCCAGATGGCACCTAC
  GTCAAACTCGGTACAGCACAGAGCAACTACCTTCCCATGGTGGTGGTGCGGGTGGAGCTG
  CTGTCAGGGGAGATCCTCCCTATACTGCAGAAGGCCTGTGTCATCGCCATGCGCTACTCG
  GTCATCCGCCGCCAATCCCGGCTCCGGCCCAGTGACCCAGAGGCAAAGGTCCTGGACTAC
  CAGACACAACAGCAGAAACTCTTTCCTCAGCTGGCCATCAGTTATGCCTTCCATTTCCTG
  GCAGTCAGCCTCTTGGAGTTCTTCCAGCACTCCTACACTGCCATTCTGAACCAAGACTTC
  AGCTTCCTGCCTGAGCTCCACGCACTGAGCACGGGCATGAAGGCCATGATGTCAGAATTC
  TGCACCCAGGGAGCTGAGATGTGCCGCAGGGCCTGTGGCGGACATGGCTACTCAAAGCTG
  AGTGGCCTGCCATCACTGGTCACCAAATTGTCGGCCTCCTGTACCTACGAGGGTGAGAAC
  ACAGTGCTCTACCTGCAGGTGGCCAGGTTCCTGGTGAAGAGCTACCTGCAGACTCAGATG
  TCCCCTGGCTCCACGCCACAGAGATCTCTCTCTCCATCTGTCGCATATCTCACCGCACCT
  GACCTGGCCAGGTGTCCAGCCCAGAGGGCAGCCGACTTCCTCTGCCCGGAGCTCTACACC
  ACGGCCTGGGCACATGTGGCAGTAAGGCTCATAAAGGACTCAGTGCAGCATTTACAGACC
  CTGACGCAATCCGGAGCTGACCAGCACGAGGCTTGGAACCAGACCACTGTCATACACCTC
  CAGGCTGCTAAGGTGCACTGCTACTATGTCACTGTGAAGGGTTTTACAGAAGCTCTGGAG
  AAACTAGAAAATGAACCAGCGATTCAGCAGGTGCTCAAGCGCCTCTGTGACCTCCATGCC
  ATACATGGAATCTTGACTAACTCGGGTGACTTTCTCCATGACGCCTTCCTGTCTGGTGCC
  CAAGTGGACATGGCAAGAACAGCCTACCTGGACCTGCTCCGCCTGATCCGGAAGGATGCC
  ATCCTGTTAACTGATGCTTTTGACTTCACCGATCAGTGTTTAAATTCAGCACTTGGCTGT
  TATGATGGAAACGTCTACGAACGCCTGTTCCAGTGGGCTCAGAAGTCACCAACCAATACT
  CAGGAGAACCCTGCCTATGAGGAATATATAAGACCACTTTTACAAAGTTGGAGATCCAAG
  CTATGA
  
  Clone variation with respect to NM_003500.3
  22 g=>t;818 a=>n
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003500 unedited
  CTTTTGTATACGACTCACTATAGGGCGGCCGCGATTCGGCACGAGGCACAAGCCTGCCAG
  AGGCTGCGGCCTACAGCCGGGGAGAGGCCAGCCCGGCCTACAGTGCGGACACAGGACAGA
  GGGGAGCCAGGTTCTTTGCACTGACCAATGCTGAGAGCAGACCCTCGGAGCAGCCGGGTT
  GGAAGTGTCTCTCCACAGTCACCAGACAGATCCAGGATAGGATGGGCAGCCCAGTGCACC
  GATTGTCATTGGGGGATACCTGGAGCAGGCAAATGCACCCCGACATAGAGAGCGAGAGGT
  ATATGCAGTCCTTTGACGTGGAACGGCTCACCAACATCCTTGATGGAGGTGCCCAGAACA
  CTGCACTCCGCAGGAAAGTTGAGAGCATCATCCACAGTTACCCGGAGTTTAGCTGTAAGG
  ACAATTATTTCATGACCCAGAATGAGCGTTATAAGGCTGCCATGCGGAGGGCATTCCACA
  TCCGGTTGATAGCTCGGCGCCTGGGTTGGTTAGAAGATGGTCGTGAATTAGGCTACGCTT
  ACAGAGCCCTTTCTGGAGACGTGGCCTTAAATATACACAGAGTCTTCGTGAGAGCCCTCA
  GGAGCCTGNGCTCAGAGGAGCAGATTGCCAAATGGGACCCACTCTGCAAAAACATCCAGA
  TCATCGCAACGTATGCACAGACAGAGTTGGGACATGGGACATATCTTCAGGGCCTGGAGA
  CTGAAGCCACCTATGACGCAGCCACCCAGGAGTTTGTGATACACAGCCCCACGCTGACTG
  CCACCAAATGGTGGCCTGGAGACTTNGGACGGTCAGCCACCCATGCCCTGNTCCCAGCCC
  AGCTGATCTGCTCNAGAGCCAGCGGNGCATGCACGCCTTTATGTGCCATTCCGAGTCTTC
  AGACACCCCCACTGCAGAATATCATGGGGACTCGNCCCAGAGGACTTGTCAACAGAATGG
  CTTCTGN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003500 unedited
  CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  CTAATTAAAAATTTTAATGTTGCATATATGCCATAGTACCATTATCACATGATGGGGCTG
  GTTGCTTCTTGAATACTGTGGGTTATTTCATAGCTTGGATCTCCAACTTTGTAAAAGGGG
  TCTTATATATTCCTCATAGGCAGGGTTCTCCTGAGTATTGGTTGGGGACTTCTGAGCCCA
  CTGGAACAGGCGTTCGTAAACGTTTCCATCATAACAGCCAAGTGCTGAATTTAAACACTG
  ATCGGGGAAGTCAAAAGCATCAGTTAACAGGATGGCATCCTTCCGGATCAGGCGGAGCAG
  GTCCAGGTAGGCTGTTCTTGCCATGTCCACTTGGGCACCAAACAGGAAGGCGTCATGGAA
  AAAGTCACCCGAGTTAGTCAAGATTCCATGTATGGCATGGAGGTCACAAAGGCGCTTGAG
  CACCTGCTGAATCGCTGGTTCATTTTCTAGTTTCTCCAGAGCTTCTGTAAAACCCTTCAC
  AGTGACATAGTAGCAGTGCACCTTACCAGCCTGGAGGTGTATGACAGTGGTCTGGTTCCA
  AGCCTCGTGCTGGTCAGCTCCGGATTGCGTCAGGGTCTGTAAATGCTGCACTGAGTCCTT
  TATGAGCCTTACTGCCACATGTGCCCCAGGCCGTGGTGTAAAGCTCCGGGCAGAGGAAAG
  TCGCTGCCCTCTGGGCTGGACACCTGCCCAGNTCAGGTGCGGTGAGATTGCGACAGATGG
  AAGAGAGATTCTGTGGCGTGGAGCCAGGGACATCTGAGTCTGCAGTACTCTCACCAGACC
  CTGCCCCTGCAGTAGACACTGGGTCTCACCTGTAATACAGGAGCCGACAATTGTGACATG
  GATGCAGCCCTCACCTGGATAACATGCCGCCCAGC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003500
• ORF Size: 2046 bp
• Insert Size: 2890
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003500.2, NP_003491.1
• RefSeq Size: 2343
• RefSeq ORF: 2046
• Locus ID: 8309
• Domains: ACOX, Acyl-CoA_dh
• Protein Pathways: Metabolic pathways, PPAR signaling pathway, Primary bile acid biosynthesis
• Gene Summary: The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe cognitive disability, and death in children. [provided by RefSeq, Mar 2009]