Frizzled 5 (FZD5) (NM_003468) Human Untagged Clone

CAT#: SC117952

FZD5 (untagged)-Human frizzled family receptor 5 (FZD5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FZD5
• Synonyms: C2orf31; HFZ5
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003468 edited
  GAATTCGGCACGAGGGAGGCAGCGCCTTCCCAAAGCAGTTTATCTTTGGACGGTTTTCTT
  TAAAGGAAAAAGCAACCAACAGGTTGCCAGCCCCGGCGCCACACACGAGACGCCGGAGGG
  AGAAGCCCCGGCCCGGATTCCTCTGCCTGTGTGCGTCCCTCGCGGGCTGCTGGAGGCGAG
  GGGAGGGAGGGGGCGATGGCTCGGCCTGACCCATCCGCGCCGCCCTCGCTGTTGCTGCTG
  CTCCTGGCGCAGCTGGTGGGCCGGGCGGCCGCCGCGTCCAAGGCCCCGGTGTGCCAGGAA
  ATCACGGTGCCCATGTGCCGCGGCATCGGCTACAACCTGACGCACATGCCCAACCAGTTC
  AACCACGACACGCAGGACGAGGCGGGCCTGGAGGTGCACCAGTTCTGGCCGCTGGTGGAG
  ATCCAATGCTCGCCGGACCTGCGCTTCTTCCTATGCTCTATGTACACGCCCATCTGTCTG
  CCCGACTACCACAAGCCGCTGCCGCCCTGCCGCTCGGTGTGCGAGCGCGCCAAGGCCGGC
  TGCTCGCCGCTGATGCGCCAGTACGGCTTCGCCTGGCCCGAGCGCATGAGCTGCGACCGC
  CTCCCGGTGCTGGGCCGCGACGCCGAGGTCCTCTGCATGGATTACAACCGCAGCGAGGCC
  ACCACGGCGCCCCCCAGGCCTTTCCCAGCCAAGCCCACCCTTCCAGGCCCGCCAGGGGCG
  CCGGCCTCGGGGGGCGAATGCCCCGCTGGGGGCCCGTTCGTGTGCAAGTGTCGCGAGCCC
  TTCGTGCCCATTCTGAAGGAGTCACACCCGCTCTACAACAAGGTGCGGACGGGCCAGGTG
  CCCAACTGCGCGGTACCCTGCTACCAGCCGTCCTTCAGTGCCGACGAGCGCACGTTCGCC
  ACCTTCTGGATAGGCCTGTGGTCGGTGCTGTGCTTCATCTCCACGTCCACCACAGTGGCC
  ACCTTCCTCATCGACATGGAACGCTTCCGCTATCCTGAGCGCCCCATCATCTTCCTGTCA
  GCCTGCTACCTGTGCGTGTCGCTGGGCTTCCTGGTGCGTCTGGTCGTGGGCCATGCCAGC
  GTGGCCTGCAGCCGCGAGCACAACCACATCCACTACGAGACCACGGGCCCTGCACTGTGC
  ACCATCGTCTTCCTCCTGGTCTACTTCTTCGGCATGGCCAGCTCCATCTGGTGGGTCATC
  CTGTCGCTCACCTGGTTCCTGGCCGCCGGCATGAAGTGGGGCAACGAGGCCATCGCGGGC
  TACGCGCAGTACTTCCACCTGGCTGCGTGGCTCATCCCCAGCGTCAAGTCCATCACGGCA
  CTGGCGCTGAGCTCCGTGGACGGGGACCCAGTGGCCGGCATCTGCTACGTGGGCAACCAG
  AACCTGAACTCGCTGCGCGGCTTCGTGCTGGGCCCGCTGGTGCTCTACCTGCTGGTGGGC
  ACGCTCTTCCTGCTGGCGGGCTTCGTGTCGCTCTTCCGCATCCGCAGCGTCATCAAGCAG
  GGCGGCACCAAGACGGACAAGCTGGAGAAGCTCATGATCCGCATCGGCATCTTCACGCTG
  CTCTATACGGTCCCCGCCAGCATTGTGGTGGCCTGCTACCTGTACGAGCAGCACTACCGC
  GAGAGCTGGGAGGCGGCGCTCACCTGCGCCTGCCCGGGCCACGACACCGGCCAGCCGCGC
  GCCAAGCCCGAGTACTGGGTGCTCATGCTCAAGTACTTCATGTGCCTGGTGGTGGGCATC
  ACGTCGGGCGTCTGGATCTGGTCGGGCAAGACGGTGGAGTCGTGGCGGCGTTTCACCAGC
  CGCTGCTGCTGCCGCCCGCGGCGCGGCCACAAGAGCGGGGGCGCCATGGCCGCAGGGGAC
  TACCCCGAGGCGAGCGCCGCGCTCACAGGCAGGACCGGGCCGCCGGGCCCCGCCGCCACC
  TACCACAAGCAGGTGTCCCTGTCGCACGTGTAGGAGGCTGCCGCCGAGGGACTCGGCCGG
  AGAGCTGAGGGGAGGGGGGCGTTTTGTTTGGTAGTTTTGCCAAGGTCACTTCCGTTTACC
  TTCATGGTGCTGTTGCCCCCTCCCGCGGCGACTTGGAGAGAGGGAAGAGGGGCGTTTTCG
  AGGAAGAACCTGTCCCAGGTCTTCTCCAAGGGGCCCAGCTCACGTGTATTCTATTTTGCG
  TTTCTTACTGCCTTCTTTATGGGAACCCTCTTTTTAATTTATATGTATTTTTCTTAATTT
  GTAACTTTGTTGCATTTTGGCAACAATTTACCTTTGCTTTGGGGGCTTTACAATCCTAAG
  GTTGGCGTTGTAATGAAGTTCCACTTGGTTCAGGTTTCTTTGAACTGTGTGGTCTCAATT
  GGGAAAATATATTTCCTATACGTGTGTCTTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003468 unedited
  AAAAACCCTCCCCCGCCCGTTGCCGTCTATAGGGCGGTAGCGTGTACGGTGGNGAGTCTA
  TATAAGCAGAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCG
  GCCGCGAATTCGGCACGAGGGAGGCAGCGCCTTCCCAAAGCAGTTTATCTTTGGACGGTT
  TTCTTTAAAGGAAAAAGCAACCAACAGGTTGCCTGCCTTGGCGCCACACACGAGACGCCG
  GAGGGAGAAGCCCCGGCCCGGATTCCTCTGCCTGTGTGCGTCCCTCGCGGGCTGCTGGAG
  GCGAGGGGAGGGAGGGGGCGATGGCTCGGCCTGACCCATCCGCGCCGCCCTCGCTGTTGC
  TGCTGCTCCTGGCGCAGCTGGTGGGCCGGGCGGCCGCCGCGTCCAAGGCCCCGGTGTGCC
  AGGAAATCACGGTGCCCATGTGCCGCGGCATCGGCTACAACCTGACGCACATGCCCAACC
  AGTTCAACCACGACACGCAGGACGAGGCGGGCCTGGAGGTGCACCAGTTCTGGCCGCTGG
  TGGAGATCCAATGCTCGCCGGACCTGCGCTTCTTCCTATGCTCTATGTACACGCCCATCT
  GTCTGCCCGACTACCACAAGCCGCTGCCGCCCTGCCGCTCGGTGTGCGAGCGCGCCAAGG
  CCGGCTGCTCGCCGCTGATGCGCCAGTACGGCTTCGCCTGGCCCGAGCGCATGAGCTGCG
  ACCGCCTCCCGGTGCTGGGCCGCGACGCCGAGGTCCTCTGCATGGATTACAACCGCAGCG
  AGGCCACCCACGGCGCCCCCCAGCCCTTTCCAACCAAGCCACCCTTCCAGGCCGCCAGGG
  GCGCCGCCTCGGGGGCGAAAGCCCCGCTGGGGGCCCGTTCCTGTGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003468 unedited
  GTCCCATTATGNATGAGGNCACGCATACNATGATCGGTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTAAAAACCACGTTTAGGGAAATATATTTTCCCAATTGAGACCACACA
  GTTCAAAAAAACCTGAACCAAGTGGAACTTCATTACAACGCCAACCTTAGGATTGTAAAG
  CCCCCAAAGCAAAGGTAAATTGTTGCCAAAATGCAACAAAGTTACAAATTAAGAAAAATA
  CCTATAAATTAAAAAGAGGGTTCCCATAAAGAAGGCAGTAAGAAACGCAAAATAGAATAC
  ACGTGAGCTGGGCCCCTTGGAGAAAACCTGGGACAGGTTCTTCCTCGAAAACGCCCCTTT
  TTCCTTTCTCCAAGTCGCCGCGGGAGGGGGCAACAGCACCATGAAGGTAAACGGAAGTGA
  CCTTGGCAAAACTACCAAACAAAACGCCCCCCTCCCCTTAACTCTCCGGCCGAGTCCCTC
  GGCGGGAGCCTCCTACACGTGCGACAGGGACACCTGCTTGTGGTAAGTGGCGGCGGGGCC
  CGGCGGCCCGGTCCTGCCTGTGAGCCGGGGCTCGCCTCGGGGTAATCCCCTGGGGCCTGG
  GGCCCCCGCTCTTGTGGCCGCGCCCGGGCGGGAACAACAACGGGTGGGGAAACCCCGCCC
  CGACTCCACCGGTTTTGTCCGAACAAATTCAGAACCCCGAGGTGTTGCCCCCCACCAGGC
  ACATGGAAGTACTTGGACATGGACACCCATTCCTCGGCCTTGGCCCCCGGTTGGCCCGGT
  TTTTTGGCCCGGGAAGCCCCAGGTTGACCCCCCCTTCCCACTCTTTCGGGAATGCCGCCC
  CTACAAGGTTGAAGGCCCCCCAAGGGTTGGGGGGGCCCGCTTTAAGCAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003468
• ORF Size: 1758 bp
• Insert Size: 2500
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_003468.2, NP_003459.2
• RefSeq Size: 2561
• RefSeq ORF: 1758
• Locus ID: 7855
• Domains: FRI, Frizzled
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway
• Gene Summary: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand. [provided by RefSeq, Jul 2008]