Chromogranin C (SCG2) (NM_003469) Human Untagged Clone

CAT#: SC117954

SCG2 (untagged)-Human secretogranin II (SCG2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SCG2
• Synonyms: CHGC; EM66; SgII; SN
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117954 sequence for NM_003469 edited (data generated by NextGen Sequencing)
  ATGGCTGAAGCAAAGACCCACTGGCTTGGAGCAGCCCTGTCTCTTATCCCTTTAATTTTC
  CTCATCTCTGGGGCTGAAGCAGCTTCATTTCAGAGAAACCAGCTGCTTCAGAAAGAACCA
  GACCTCAGGTTGGAAAATGTCCAAAAGTTTCCCAGTCCTGAAATGATCAGGGCTTTGGAG
  TACATAGAAAACCTCCGACAACAAGCTCATAAGGAAGAAAGCAGCCCAGATTATAATCCC
  TACCAAGGTGTCTCTGTCCCCCTTCAGCAAAAAGAAAATGGCGATGAAAGCCACTTGCCC
  GAGAGGGATTCACTGAGTGAAGAAGACTGGATGAGAATAATACTCGAAGCTTTGAGACAG
  GCTGAAAATGAGCCTCAGTCTGCACCAAAAGAAAATAAGCCCTATGCCTTGAATTCAGAA
  AAGAACTTTCCAATGGACATGAGTGATGATTATGAGACACAGCAGTGGCCAGAAAGAAAG
  CTTAAGCACATGCAATTCCCTCCTATGTATGAAGAGAATTCCAGGGATAACCCCTTTAAA
  CGCACAAATGAAATAGTGGAGGAACAATATACTCCTCAAAGCCTTGCTACATTGGAATCT
  GTCTTCCAAGAGCTGGGGAAACTGACAGGACCAAACAACCAGAAACGTGAGAGGATGGAT
  GAGGAGCAAAAACTTTATACGGATGATGAAGATGATATCTACAAGGCTAATAACATTGCC
  TATGAAGATGTGGTCGGGGGAGAAGACTGGAACCCAGTAGAGGAGAAAATAGAGAGTCAA
  ACCCAGGAAGAGGTGAGAGACAGCAAAGAGAATATAGAAAAAAATGAACAAATCAACGAT
  GAGATGAAACGCTCAGGGCAGCTTGGCATCCAGGAAGAAGATCTTCGGAAAGAGAGTAAA
  GACCAACTCTCAGATGATGTCTCCAAAGTAATTGCCTATTTGAAAAGGTTAGTAAATGCT
  GCAGGAAGTGGGAGGTTACAGAATGGGCAAAATGGGGAAAGGGCCACCAGGCTTTTTGAG
  AAACCTCTTGATTCTCAGTCTATTTATCAGCTGATTGAAATCTCAAGGAATTTACAGATA
  CCCCCAGAAGACTTAATTGAGATGCTCAAAACTGGGGAGAAGCCGAATGGATCAGTGGAA
  CCGGAGCGGGAGCTTGACCTTCCTGTTGACCTAGATGACATCTCAGAGGCTGACTTAGAC
  CATCCAGACCTGTTCCAAAATAGGATGCTCTCCAAGAGTGGCTACCCTAAAACACCTGGT
  CGTGCTGGGACTGAGGCCCTACCAGACGGGCTCAGTGTTGAGGATATTTTAAATCTTTTA
  GGGATGGAGAGTGCAGCAAATCAGAAAACGTCGTATTTTCCCAATCCATATAACCAGGAG
  AAAGTTCTGCCAAGGCTCCCTTATGGTGCTGGAAGATCTAGATCGAACCAGCTTCCCAAA
  GCTGCCTGGATTCCACATGTTGAAAACAGACAGATGGCATATGAAAACCTGAACGACAAG
  GATCAAGAATTAGGTGAGTACTTGGCCAGGATGCTAGTTAAATACCCTGAGATCATTAAT
  TCAAACCAAGTGAAGCGAGTTCCTGGTCAAGGCTCATCTGAAGATGACCTGCAGGAAGAG
  GAACAAATTGAGCAGGCCATCAAAGAGCATTTGAATCAAGGCAGCTCTCAGGAGACTGAC
  AAGCTGGCCCTGGTGAGCAAAAGGTTCCCTGTGGGGCCCCCGAAGAATGATGATACCCCA
  AATAGGCAGTACTGGGATGAAGATCTGTTAATGAAAGTGCTGGAATACCTCAACCAAGAA
  AAGGCAGAAAAGGGAAGGGAGCATATTGCTAAGAGAGCAATGGAAAATATGTAA
  
  Clone variation with respect to NM_003469.4
  1691 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003469 unedited
  AGTATATTTGTATACGACTTCACTATAGGGCGGCCGCGAATTCGCACGAGGCTGAACCCG
  GTGACGTCAGTGTGGCAGTGCGGAGTCAGGCGCAGCGGCTCCCTATAAGCAGAGGAGCTG
  TCCGTGTGCTGAAACGGCCCGAGAAGCTCGCCCGGAGAACGGGGAGGAATATGCTGTGGA
  GCTCCTCTGCCATATAAACAAAAAGAGGAAATCTTTCAAACATGGCTGAAGCAAAGACCC
  ACTGGCTTGGAGCAGCCCTGTCTCTTATCCCTTTAATTTTCCTCATCTCTGGGGCTGAAG
  CAGCTTCATTTCAGAGAAACCAGCTGCTTCAGAAAGAACCAGACCTCAGGTTGGAAAATG
  TCCAAAAGTTTCCCAGTCCTGAAATGATCAGGGCTTTGGAGTACATAGAAAACCTCCGAC
  AACAAGCTCATAAGGAAGAAAGCAGCCCAGATTATAATCCCTACCAAGGTGTCTCTGTCC
  CCCTTCAGCAAAAAGAAAATGGCGATGAAAGCCACTTGCCCGAGAGGGATTCACTGAGTG
  AAGAAGACTGGATGAGAATAATACTCGAAGCTTTGAGACAGGCTGAAAATGAGCCTCAGT
  CTGCACCANAAGAAAATAAGCCCTATGCCTTGAATTCAGAANAGAACTTTCCAATGGACA
  TGAGTGATGATTATGAGACACAGCAGTGGCCAGAAAGAAAGCTTAAGCACATGCCATTCC
  CTNCTATGTATGAAGAGAATTCCAGGGGATACCCCCTCTAACGCCCAAATGAATAGTGGA
  GGACCATATACTCCTCAAAGCCCTGCTACATTGGAATCTGTCTCCCAGAGCTCGGGGAAC
  TGACCGGACCAACCACCNNAACCTGAAAGGATTGATGAAGACCAAAAACTTATACCCATG
  ATGAGATGATATCTACAGGGCTAATACACTGCCTATGAAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003469 unedited
  CGCAATCTAGTGTCGAGTTTTTTTTTTTTTTTTTTCCAGAAAAACATTTATTAATCAACA
  GTAAAACACACAATAGAAAAGGCCTTATAAATAAAACTATATATTTATAATGCTTTATTT
  TTTTGGTCCAGTACTCCACAAAACACTACAGACAGTAACAAAATAATTCAATAAATATTA
  AAAACTTTCAATAGAATTATAGGACACTTTTTTATCATATGTGAGCATCAACAATGCCAC
  AGCCATTAGATATACTATTAAACACAGTCATAGATATCTTTCTTGAATAATGGACATAAT
  AAATTTTTTATCAAGGAGTCATAACATTTACACATATCCATACACAAGATAACAGCTCAG
  AGGAAATGAAGCAGACTCCCCAGTGACCTGGTTTCATCTGCCTGTACATCATTTAAAGAT
  ATTACAGTGTTAACAGGATAGAAGTCAACACACTGAAGAGAAATGTTGGGATTTGCTTGG
  GGTGGGAGGAATGAAAGTAGGGTAATTAATGAAAGCAGCTTACATATTTTCCATTGCTCT
  CTTACAATATGCTCCCTTCCCTTTTCTGCCTTTTCTTGGTTGAGGTATTCCAGCACTTTC
  ATTAACAGATCTTCATCCCAGTACTGCCTATTTGGGGTATCATCATTCTTCGGAGGCCCC
  ACAGGGAACCTTTTGCTCACCAGGGCCAGCTTGTCAGTCTCCTGAGAGCTGCCTTGATTC
  AAATGCTCTTTGATGGCCTGCTCAATTTGGTCCTCTTCCTGCAAGTCATCTTCAGATGAG
  CCTTGACCAGAAACTCGCTTCACTTGGTTTGAATAATGATCTCAGGGTATTTACTAGCAT
  CCTGGNCAGTACTCACCTATTTCTGATCCTGGCGTTCAGGTTTCATATGCATCTGTCTGT
  TTCACATGTGAATCCAGCAGCTTTGGAAGCTGTTCGATCTAAATCTTCGCACATATGGAG
  CCTGGAATACTTTTCTGTTTATGATGGGAAATCAN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003469
• ORF Size: 1854 bp
• Insert Size: 2440
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_003469.3, NP_003460.2
• RefSeq Size: 2490
• RefSeq ORF: 1854
• Locus ID: 7857
• Domains: Granin
• Protein Families: Secreted Protein, Transmembrane
• Gene Summary: The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq, Jul 2008]