USP7 (NM_003470) Human Untagged Clone

CAT#: SC117955

USP7 (untagged)-Human ubiquitin specific peptidase 7 (herpes virus-associated) (USP7)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: USP7
• Synonyms: HAUSP; TEF1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_003470 edited
  GCACGAGGGAGCAAGTACGTGCGCGTCTCCCTGCCGCCGCCGCCGCCCGCCGCGGGCCGC
  CCCGGGGCCGCCGTCGCCGACGACGCGCGGGAGGAGGAGGAGGAGGCCGCCCCGCCGCCG
  CCGCCGCCGCCGCCGCCCCGGCTCGCCGCCGCCCGCCCGCCGGGCTCGCAGCCCCGGCCC
  CCGGCCGCAGGCGAGGCCCAGGCCGCGGCCGACATGAACCACCAGCAGCAGCAGCAGCAG
  CAGAAAGCGGGCGAGCAGCAGTTGAGCGAGCCCGAGGACATGGAGATGGAAGCGGGAGAT
  ACAGATGACCCACCAAGAATTACTCAGAACCCTGTGATCAATGGGAATGTGGCCCTGAGT
  GATGGACACAACACCGCGGAGGAGGACATGGAGGATGACACCAGTTGGCGCTCCGAGGCA
  ACCTTTCAGTTCACTGTGGAGCGCTTCAGCAGACTGAGTGAGTCGGTCCTTAGCCCTCCG
  TGTTTTGTGCGAAATCTGCCATGGAAGATTATGGTGATGCCACGCTTTTATCCAGACAGA
  CCACACCAAAAAAGCGTAGGATTCTTTCTCCAGTGCAATGCTGAATCTGATTCCACGTCA
  TGGTCTTGCCATGCACAAGCAGTGCTGAAGATAATAAATTACAGAGATGATGAAAAGTCG
  TTCAGTCGTCGTATTAGTCATTTGTTCTTCCATAAAGAAAATGATTGGGGATTTTCCAAT
  TTTATGGCCTGGAGTGAAGTGACCGATCCTGAGAAAGGATTTATAGATGATGACAAAGTT
  ACCTTTGAAGTCTTTGTACAGGCGGATGCTCCCCATGGAGTTGCGTGGGATTCAAAGAAG
  CACACAGGCTACGTCGGCTTAAAGAATCAGGGAGCGACTTGTTACATGAACAGCCTGCTA
  CAGACGTTATTTTTCACGAATCAGCTACGAAAGGCTGTGTACATGATGCCAACCGAGGGG
  GATGATTCGTCTAAAAGCGTCCCTTTAGCATTACAAAGAGTGTTCTATGAATTACAGCAT
  AGTGATAAACCTGTAGGAACAAAAAAGTTAACAAAGTCATTTGGGTGGGAAACTTTAGAT
  AGCTTCATGCAACATGATGTTCAGGAGCTTTGTCGAGTGTTGCTCGATAATGTGGAAAAT
  AAGATGAAAGGCACCTGTGTAGAGGGCACCATACCCAAATTATTCCGCGGCAAAATGGTG
  TCCTATATCCAGTGTAAAGAAGTAGACTATCGGTCTGATAGAAGAGAAGATTATTATGAT
  ATCCAGCTAAGTATCAAAGGAAAGAAAAATATATTTGAATCATTTGTGGATTATGTGGCA
  GTAGAACAGCTCGATGGGGACAATAAATACGACGCTGGGGAACATGGCTTACAGGAAGCA
  GAGAAAGGTGTGAAATTCCTAACATTGCCACCAGTGTTACATCTACAACTGATGAGATTT
  ATGTATGACCCTCAGACGGACCAAAATATCAAGATCAATGATAGGTTTGAATTCCCAGAG
  CAGTTACCACTTGATGAATTTTTGCAAAAAACAGATCCTAAGGACCCTGCAAATTATATT
  CTTCATGCAGTCCTGGTTCATAGTGGAGATAATCATGGTGGACATTATGTGGTTTATCTA
  AACCCCAAAGGGGATGGCAAATGGTGTAAATTTGATGACGACGTGGTGTCAAGGTGTACT
  AAAGAGGAAGCAATTGAGCACAATTATGGGGGTCACGATGACGACCTGTCTGTTCGACAC
  TGCACTAATGCTTACATGTTAGTCTACATCAGGGAATCAAAACTGAGTGAAGTTTTACAG
  GCGGTCACCGACCATGATATTCCTCAGCAGTTGGTGGAGCGATTACAAGAAGAGAAAAGG
  ATCGAGGCTCAGAAGCGGAAGGAGCGGCAGGAAGCCCATCTCTATATGCAAGTGCAGATA
  GTCGCAGAGGACCAGTTTTGTGGCCACCAAGGGAATGACATGTACGATGAAGAAAAAGTG
  AAATACACTGTGTTCAAAGTATTGAAGAACTCCTCGCTTGCTGAGTTTGTTCAGAGCCTC
  TCTCAGACCATGGGATTTCCACAAGATCAAATTCGATTGTGGCCCATGCAAGCAAGGAGT
  AATGGAACAAAACGACCAGCAATGTTAGATAATGAAGCCGACGGCAATAAAACAATGATT
  GAGCTCAGTGATAATGAAAACCCTTGGACAATATTCCTGGAAACAGTTGATCCCGAGCTG
  GCTGCTAGTGGAGCGACCTTACCCAAGTTTGATAAAGATCATGATGTAATGTTATTTTTG
  AAGATGTATGATCCCAAAACGCGGAGCTTGAATTACTGTGGGCATATCTACACACCAATA
  TCCTGTAAAATACGTGACTTGCTCCCAGTTATGTGTGACAGAGCAGGATTTATTCAAGAT
  ACTAGCCTTATCCTCTATGAGGAAGTTAAACCGAATTTAACAGAGAGAATTCAGGACTAT
  GACGTGTCTCTTGATAAAGCCCTTGATGAACTAATGGATGGTGACATCATAGTATTTCAG
  AAGGATGACCCTGAAAATGATAACAGTGAATTACCCACCGCAAAGGAGTATTTCCGAGAT
  CTCTACCACCGCGTTGATGTCATTTTCTGTGATAAAACAATCCCTAATGATCCTGGATTT
  GTGGTTACGTTATCAAATAGAATGAATTATTTTCAGGTTGCAAAGACAGTTGCACAGAGG
  CTCAACACAGATCCAATGTTGCTGCAGTTTTTCAAGTCTCAAGGTTATAGGGATGGCCCA
  GGTAATCCTCTTAGACATAATTATGAAGGTACTTTAAGAGATCTTCTACAGTTCTTCAAG
  CCTAGACAACCTAAGAAACTTTACTATCAGCAGCTTAAGATGAAAATCACAGACTTTGAG
  AACAGGCGAAGTTTTAAATGTATATGGTTAAACAGCCAATTTAGGGAAGAGGAAATAACA
  CTATATCCAGACAAGCATGGGTGTGTCCGGGACCTGTTAGAAGAATGTAAAAAGGCCGTG
  GAGCTTGGGGAGAAAGCATCAGGGAAACTTAGGCTGCTAGAAATTGTAAGCTACAAAATC
  ATTGGTGTTCATCAAGAAGATGAACTATTAGAATGTTTATCTCCTGCAACGAGCCGGACG
  TTTCGAATAGAGGAAATCCCTTTGGACCAGGTGGACATAGACAAAGAGAATGAGATGCTT
  GTCACAGTGGCGCATTTCCACAAAGAGGTCTTCGGAACGTTCGGAATCCCGTTTTTGCTG
  AGGATACACCAGGGCGAGCATTTTCGAGAAGTGATGAAGCGAATCCAGAGCCTGCTGGAC
  ATCCAGGAGAAGGAGTTTGAGAAGTTTAAATTTGCAATTGTAATGATGGGCCGACACCAG
  TACATAAATGAAGACGAGTATGAAGTAAATTTGAAAGACTTTGAGCCACAGCCCGGTAAT
  ATGTCTCATCCTCGGCCTTGGCTAGGGCTCGACCACTTCAACAAAGCCCCAAAGAGGAGT
  CGCTACACTTACCTTGAAAAGGCCATTAAAATCCATAACTGATTTCCAAGCTGGTGTGTT
  CAAGGCGAGGACGGTGTGTGGGTGGCCCCTTAACAGCCTAGAACTTTGGTGCACGTGCCC
  TCTAGCCGAAGTCTTCAGCAAGAGGATTCGCTGCTGGTGTTAATTTTATTTTATTGAGGC
  TGTTCAGTTTGGCTTCTCTGTATCTATTGACTGCCCTTTTTGAGCAAAATGAAGATGTTT
  TTATAAAGCTTGGATGCCAATGAGAGTTATTTTATGGTAACCACAGTGCAAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003470 unedited
  ATCATTTGTATACGACTCACTATGGGCGGCCCGCGATTCGGCACGAGGGAGCAAGTACGT
  GCGCGTCTCCCTGCCGCCGCCGCCGCCCGCCGCGGGCCGCCCCGGGGCCGCCGTCGCCGA
  CGACGCGCGGGAGGAGGAGGAGGAGGCCGCCCCGCCGCCGCCGCCGCCGCCGCCGCCCCG
  GCTCGCCGCCGCCCGCCCGCCGGGCTCGCAGCCCCGGCCCCCGGCCGCAGGCGAGGCCCA
  GGCCGCGGCCGACATGAACCACCAGCAGCAGCAGCAGCAGCATAAAGCGGGCGAGCAGCA
  GTTGAGCGAGCCCGATGACATGGAGATGGAAGCGGGAGATACAGATGACCCACCAAGAAT
  TACTCACAACCCTGTGATCAATGGGAATGTGGCCCTGAGTGATGGACACAACACCGCGGA
  GGAGGACATGGAGGATGACACCAGTTGGCGCTCCGAGGCAACCTTTCAGTTCACTGTGGA
  GCGCTTCAGCAGACTGAGTGAGTCGGTCCTTAGCCCTCCGTGTTTTGTGCGAAATCTGCC
  ATGGAAGATTATGGTGATGCCACGCTTTTATCCAGACAGACCACACCAAAAAAGCGTAGG
  ATTCTTTCTCCAGTGCAATGCTGAATCTGATTCCACGTCATGGTCTTGCCATGCACAAGC
  AGTGCTGAAGATAATAAATTACAGAGATGATGAAAAGTCCCTCAGCCGTCGTATTAGTCA
  TTTGCTCTTCCATAAAGANAATGATTGGGGATTTTCCAATTTTATGGCCTGGAGTGAAAT
  GACCGATCCTGAGAAAGGCTTATAGATGATGACCAAGTTCCTTTGAAGTCTTTGGACGGC
  CGATGCTCCCCTGGAGTGCGTGGGATTAAATACCACAACAGCTACCCCGCTTAAGATCAG
  GAGCGATTTGTACATGACAGCTGCTCAAACGTATTTTCCACAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003470 unedited
  ATGGACGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCATTTTTAACTTTT
  TTACAAAGTCGACAGCTTACTAACCACTAGTGAGCATGCCCTCTTGCTAAAAGGCTTTCT
  TGTCGTCTGTTCCACTTTAACGAAATTCTATTTATAATCCTTTCACCTGCTCGTATGAAC
  TGTTGAGATCGTAAGTCTGCCAAGGCAGCAGAGTAAACCTTAATTGAATTTAACAATGTT
  CTTGATTTAATAAAAAGACCCCCACAATGTCTGTCCGGACTGTATTCAGTGCATCCACTT
  TGCAAAGGGGCTGCAGACAGTAGTGGCTGACGAGGTGAGACAAGTTTATTAAAAAGCCCC
  CAGGCAGCTGGAGGAGGAGAACCCGAGGAAGGGCCGACAATGCACACAATGAAGGGAAGA
  GCGCTATTTATTAGGTTGTGAGTTTCTCTGTTTTGCCTTAACAGATGCACAAAAGGTCAT
  TGAAAGTATAACTGAAGGAAATAGGTCAGACGAGCCTAAACACAAGACTTGCTAGCTGCA
  GGGCTGGTGCACGGGACCCCAGGAAGGCAGCCGAGCCACTCGTGCCCACTAGGGACAGCC
  CAGAGACCTTGAGCCAGGGACCCCCGATCCACTAACCTCTTCNTCCCCATTGCGCTGACA
  GTTGCCTTGCACTGTGGTTACCATANAATAACTCTCATTGGCATCCCAAGCTTTATAAAA
  ACCATCTCCATTTTGCTCAAAAAGGGCAGTCAATAGATACAGAGAAGCCCAACTGAACCG
  NCCTCATAAAATAAATTTACACAGCAGCGAATCCTTTGCTGTAGACTTCGCTAGAGGCAC
  TGCACCAAAATCTTAGCTGTTAAGGGCCACCCCCCACCGCCTCGCCTTGAACCCCCACTT
  TGAAATCAGTTATGATTTTATGGCCTTTCAGGTAGGGGACCACTCTCTTTGGGCCCTGTG
  AAGGGCCAAGCCTATCCAGCCAAGGATAAACATTACCGGCTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003470
• ORF Size: 3309 bp
• Insert Size: 4820
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_003470.1, NP_003461.1
• RefSeq Size: 4022
• RefSeq ORF: 3309
• Locus ID: 7874
• Domains: UCH, MATH
• Protein Families: Druggable Genome, Protease
• Gene Summary: The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016]
  Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.