NR2C2 (NM_003298) Human Untagged Clone

CAT#: SC118058

NR2C2 (untagged)-Human nuclear receptor subfamily 2, group C, member 2 (NR2C2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NR2C2
• Synonyms: TAK1; TR4
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_003298 edited
  ATGACCAGCCCCTCCCCACGCATCCAGATAATCTCCACCGACTCTGCTGTAGCCTCACCT
  CAGCGCATTCAGGGCTCTGAACCTGCCTCTGGCCCATTGAGTGTTTTCACATCTTTGAAC
  AAAGAGAAGATTGTCACAGACCAGCAGACAGGACAGAAAATCCAGATAGTCACCGCAGTG
  GACGCCTCCGGATCCCCCAAACAGCAGTTCATCCTGACCAGCCCAGATGGAGCTGGAACT
  GGGAAGGTGATCCTGGCTTCCCCAGAGACATCCAGCGCCAAGCAACTCATATTCACCACC
  TCAGACAACCTCGTCCCTGGCAGGATCCAGATTGTCACGGATTCTGCCTCTGTGGAGCGT
  TTACTGGGGAAGACGGACGTCCAGCGGCCCCAGGTGGTAGAGTACTGTGTGGTCTGTGGC
  GACAAAGCCTCCGGCCGTCACTATGGGGCTGTCAGTTGTGAAGGTTGCAAAGGTTTCTTC
  AAAAGGAGTGTGAGGAAAAATTTGACCTACAGCTGCCGGAGCAACCAAGACTGCATCATC
  AATAAACATCACCGGAACCGCTGTCAGTTTTGCCGGCTGAAAAAATGCTTAGAGATGGGC
  ATGAAAATGGAATCTGTGCAGAGTGAACGGAAGCCCTTCGATGTGCAACGGGAGAAACCA
  AGCAATTGTGCTGCTTCAACTGAGAAAATCTATATCCGGAAAGACCTGAGAAGTCCCCTG
  ATAGCTACTCCCACGTTTGTGGCAGACAAAGATGGAGCAAGACAAACAGGTCTTCTTGAT
  CCAGGGATGCTTGTGAACATCCAGCAGCCTTTGATACGTGAGGATGGTACAGTTCTCCTG
  GCCACGGATTCTAAGGCTGAAACAAGCCAGGGAGCTCTGGGCACACTGGCAAATGTAGTG
  ACCTCCCTTGCCAACCTAAGTGAATCTTTGAACAACGGTGACACTTCAGAAATCCAGCCA
  GAGGACCAGTCTGCAAGTGAGATAACTCGGGCATTTGATACCTTAGCTAAAGCACTTAAT
  ACCACAGACAGCTCCTCTTCTCCAAGCTTGGCAGATGGGATAGACACCAGTGGAGGAGGG
  AGCATCCACGTCATCAGCAGAGACCAGTCGACACCCATCATTGAGGTTGAAGGCCCCCTC
  CTTTCAGACACACACGTCACATTTAAGCTAACAATGCCCAGTCCAATGCCAGAGTACCTC
  AACGTGCACTACATCTGTGAGTCTGCATCCCGTCTGCTTTTCCTCTCAATGCACTGGGCT
  CGGTCAATCCCAGCCTTTCAGGCACTTGGGCAGGACTGCAACACCAGCCTTGTGCGGGCC
  TGCTGGAATGAGCTCTTCACCCTCGGCCTGGCCCAGTGTGCCCAGGTCATGAGTCTCTCC
  ACCATCCTGGCTGCCATTGTCAACCACCTGCAGAACAGCATCCAGGAAGATAAACTTTCT
  GGTGACCGGATAAAGCAAGTCATGGAGCACATCTGGAAGCTGCAGGAGTTCTGTAACAGC
  ATGGCGAAGCTGGATATAGATGGCTATGAGTATGCATACCTTAAAGCTATAGTTCTCTTT
  AGCCCCGATCATCCAGGTTTGACCAGCACAAGCCAGATTGAAAAATTCCAAGAAAAGGCA
  CAGATGGAGTTGCAGGACTATGTTCAGAAAACCTACTCAGAAGACACCTACCGATTGGCC
  CGGATCCTCGTTCGCCTGCCGGCACTCAGGCTGATGAGCTCCAACATAACAGAAGAACTT
  TTTTTTACTGGTCTCATTGGCAATGTTTCGATAGACAGCATAATCCCCTACATCCTCAAG
  ATGGAGACAGCAGAGTATAATGGCCAGATCACCGGAGCCAGTCTATAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003298 unedited
  CAAAACCATTCGCACGAGGAGAAAACCAACAGTGAGATCAAGAATTGTTCTCTAATGATC
  TTGGTTCACCATGGCTACAAATATGGAGGGGCTGGTTCAGCACAGAGTGGGGACCCAGCA
  GGTGGCTGAGGTAACACGTACACAGACCTCTCGGCCGGAATCTCCAGGGATGACCAGCCT
  CTTCCTCGCATCCAGATAATCTCCACCGACTCTGCTGTAGCCTCACCTCAGCGCATTCAG
  GGCTCTGAACCTGCCTCTGGCCCATTGAGTGTTTTCACATCTTTGAACAAAGAGAAGATT
  GTCACAGACCAGCAGACAGGACAGAAAATCCAGATAGTCACCGCAGTGGACGCCTCCGGA
  TCCCCCAAACAGCAGTTCATCCTGACCAGCCCAGATGGAGCTGGAACTGGGAAGGTGATC
  CTGGCTTCCCCAGAGACATCCAGCGCCAAGCAACTCATATTCACCACCTCAGACAACCTC
  GTCCCTGGCAGGATCCAGATTGTCACGGATTCTGCCTCTGTGGAGCGTTTACTGGGGAAG
  ACGGACGTCCAGCGGCCCCAGGTGGTAGAGTACTGTGTGGTCTGTGGCGACAAAGCCTCC
  GGCCGTCACTATGGGGCTGTCAGTTGTGAAGGTTGCAAAGGTTTCTTCAAAAGGAGTGTG
  AGGAAAAATTTGACCTACAGCTGCCNGAGCAACCAAGACTGCATCATCAATAAACATCAC
  CGGGAACGCTGTCAGTTTTGCCGGCTGGAAAAATGCTTAGAGATGGGCATGAAAATGGAA
  TCTGTGCAGAGTGAACGAAAGCCCTTCCATGTGCAACGGAAGGAACCAAGCAATTGTGCT
  GCTTCACCTGAGAAAACTATATCCCGAAAAGACTGAAAAGTCCCCTGGAAGCTACTCCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003298 unedited
  GGCCGCAATCTAGCGTCGAGTTTTTTTTTTTTTTTTTTGTTTTTTGCCCTTTGAGAATTT
  CTAAATACAAATTGAGTTAAAAGATTGTTCCAAAATCTGCTGCTTCATCAAAAGGCATTA
  AAACATTTCTTATGTCAGGAAAGGATCCTACTAGTCTTTTAATTGCTATTGTCTGGGATT
  AACAGATAAGGAGAAACCAGACAGGAAATGGCTAACATATGGAAATATTTGCACATACCA
  AAATACCACTACTTTTCTTTGTATGTGAACGGTCCTGGAAGGATTCTGTTGCTCCTTGGC
  AGGTGTGTGGTTTGCGCTATAGACTGGCTCCGGTGATCTGGCCATTATACTCTGCTGTCT
  CCATCTTGAGGATGTAGGGGATTATGCTGTCTATCGAAACATTGCCAATGAGACCAGTAA
  AAAAAAGCTCTTCTGCTATGTTGGAGCTCATCACCCCGAGTGCCGGCAGGCGAACGAGGA
  TCCGGGCCCATCGGTAGGTGTCTTCTGAGTAGGTTTTCTGAACATAGAGCTGGACCTGCA
  TCTGTGCCCTTTCTTGGAATTTTTGAATCTGGCTTGTGCTGGAGCAACCTGGAAGACCGG
  GGCTAAAAAACACTTTTCCCTTGAAGTTTCGCCCCCTGTAGTCCTCGTTCTGCCACTTAA
  GCGTGCTGTAGCCCAACCGGCTCGCACTACCACGAGGGCGCCGGGCCTGGCTTTTCCCCG
  GCCGCGAAAGGTGCCCTGCTCGGTTCTTATTTACAAGTGTTAGCATTCCCCCGCCTATGG
  CGGCCAAATTCTTCCTCTCCCCACCGGTCCCCCGGGCGGGGGAAGAGCGGTTACCAGCCG
  CCGCTCGCCGCCGCCCCTCCCCGACCATCATAGTGTTTAGGGTCTATCGCCCCGCCTCGT
  ATGTAGGCCGAGCACACGCCTCCCTCGCTTCGTTGTGTGGGGCCGCCCGACGCCCGCTCG
  AACTGCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003298
• Insert Size: 2350 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003298.2, NP_003289.2
• RefSeq Size: 2416 bp
• RefSeq ORF: 1848 bp
• Locus ID: 7182
• Cytogenetics: 3p25.1
• Domains: HOLI, zf-C4
• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Gene Summary: 'This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]'
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.