TIMP1 (NM_003254) Human Untagged Clone

CAT#: SC118082

TIMP1 (untagged)-Human TIMP metallopeptidase inhibitor 1 (TIMP1)


  "NM_003254" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol TIMP1
Synonyms CLGI; EPA; EPO; HCI; TIMP; TIMP-1
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC118082 sequence for NM_003254 edited (data generated by NextGen Sequencing)
ATGGCCCCCTTTGAGCCCCTGGCTTCTGGCATCCTGTTGTTGCTGTGGCTGATAGCCCCC
AGCAGGGCCTGCACCTGTGTCCCACCCCACCCACAGACGGCCTTCTGCAATTCCGACCTC
GTCATCAGGGCCAAGTTCGTGGGGACACCAGAAGTCAACCAGACCACCTTATACCAGCGT
TATGAGATCAAGATGACCAAGATGTATAAAGGGTTCCAAGCCTTAGGGGATGCCGCTGAC
ATCCGGTTCGTCTACACCCCCGCCATGGAGAGTGTCTGCGGATACTTCCACAGGTCCCAC
AACCGCAGCGAGGAGTTTCTCATTGCTGGAAAACTGCAGGATGGACTCTTGCACATCACT
ACCTGCAGTTTCGTGGCTCCCTGGAACAGCCTGAGCTTAGCTCAGCGCCGGGGCTTCACC
AAGACCTACACTGTTGGCTGTGAGGAATGCACAGTGTTTCCCTGTTTATCCATCCCCTGC
AAACTGCAGAGTGGCACTCATTGCTTGTGGACGGACCAGCTCCTCCAAGGCTCTGAAAAG
GGCTTCCAGTCCCGTCACCTTGCCTGCCTGCCTCGGGAGCCAGGGCTGTGCACCTGGCAG
TCCCTGCGGTCCCAGATAGCCTGA

Clone variation with respect to NM_003254.2
372 t=>c
>OriGene 5' read for NM_003254 unedited
GGTAACATCTTGGATTTTGTAATCACGACTTACTATNAGGGCGGCACGCGCAATTCGGCA
CGAGGCCCAGCGCCCAGAANAAACACCAGAANAACCCACCATGGCCCCCTTTGAGCCCCT
GGCTTCTGGCATCCTGTTGTTGCTGTGGCTGATAGCCCCCAGCAGGGCCTGCACCTGTGT
CCCACCCCACCCACAGACGGCCTTCTGCAATTCCGACCTCGTCATCAGGGCCAAGTTCGT
GGGGACACCAGAAGTCAACCAGACCACCTTATACCAGCGTTATGAGATCAAGATGACCAA
GATGTATAAAGGGTTCCAAGCCTTAGGGGATGCCGCTGACATCCGGTTCGTCTACACCCC
CGCCATGGAGAGTGTCTGCGGATACTTCCACAGGTCCCACAACCGCAGCGAGGAGTTTCT
CATTGCTGGAAAACTGCAGGATGGACTCTTGCACATCACTACCTGCAGTTTCGTGGCTCC
CTGGAACAGCCTGAGCTTAGCTCAGCGCCGGGGCTTCACCAAGACCTACACTGTTGGCTG
TGAGGAATGCACAGTGTTTCCCTGTTTATCCATCCCCTGCAAACTGCAGAGTGGCACTCA
TTGCTTGTGGACGGACCAGCTCCTCCAAGGCTCTGAAAAGGGCTTCCAGTCCCGTCACCT
TGCCTGCCTGCCTCGGGAGCCAGGGCTGTGCACCTGGCAGTCCCTGCGGTCCCAGATAGC
CTGAATCCTGCCCGGAGTGGAAGCTGAAGCCTGCACAGTGTCCACCCTGTTCCCACTCCC
ATCTTTCTTNCCCGGACAATGAATANAGAGTTACCACCCAGCAAAAAAAAAAAAAAAAAA
CTCGACTCTAGATTGCGGCCCGCGTCATAGCTGTTTCCTGAACAGACCCNGGNTGA
>OriGene 3' read for NM_003254 unedited
CCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTGCTGGGTGGTAACTCTTTATTTC
ATTGTCCGGAAGAAAGAGGGAGTGGGAACAGGGTGGACACTGTGCAGGCTTCAGCTTCCA
CTCCGGGCAGGATTCAGGCTATCTGGGACCGCAGGGACTGCCAGGTGCACAGCCCTGGCT
CCCGAGGCAGGCAGGCAAGGTGACGGGACTGGAAGCCCTTTTCAGAGCCTTGGAGGAGCT
GGTCCGTCCACAAGCAATGAGTGCCACTCTGCAGTTTGCAGGGGATGGATAAACAGGGAA
ACACTGTGCATTCCTCACAGCCAACAGTGTAGGTCTTGGTGAAGCCCCGGCGCTGAGCTA
AGCTCAGGCTGTTCCAGGGAGCCACGAAACTGCAGGTAGTGATGTGCAAGAGTCCATCCT
GCAGTTTTCCAGCAATGAGAAACTCCTCGCTGCGGTTGTGGGACCTGTGGAAGTATCCGC
AGACACTCTCCATGGCGGGGGTGTAGACCAACCGGATGTCANCGGCATCCCCTAAGGCTT
GGAACCCTTTATACATCTTGGCCATCTTGATCTCATAACGCTGGTATAAGGTGGTCTGGT
TGACTTCTGGTGTCCCCACAAACTTGGCCCTGATGACCAGGTCCGAACTGCCACAACGCC
GCCTGTGGGTGGCGCGGGACACAGGTGCAAGCCCTGCTGGGGGCTATCAACCCCCGCAAC
CCAAGATGCCAAACCCAGGGGCTCAAAGGGGCTCTGGGGGGTTCCCCTGTGCTTTCTTGG
ACGCTGGCTCCGGCCAACCCCGGGCCCGCCACANCCAGCCGATTCAAAATCCCGACGGTT
TCTAAACAAGTTCCGTTTATATAACTTCCCAGTACCCCCCCCCCCCATCGCCCCACGGGC
GCGGTCTTCGAATTCCGACAACACTGTTCCCTTGGCCCCACAAACCCCCTGGTCTTCAGG
GTCGCCCCTCTCAT
Restriction Sites NotI-NotI     
ACCN NM_003254
Insert Size 870 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_003254.2, NP_003245.1
RefSeq Size 931 bp
RefSeq ORF 624 bp
Locus ID 7076
Cytogenetics Xp11.3
Domains NTR
Protein Families Druggable Genome, Secreted Protein
Gene Summary 'This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.