CD43 (SPN) (NM_003123) Human Untagged Clone

CAT#: SC118170

SPN (untagged)-Human sialophorin (SPN), transcript variant 2


  "NM_003123" in other vectors (7)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

Product Images

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SPN
Synonyms CD43; GALGP; GPL115; LSN
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC118170 sequence for NM_003123 edited (data generated by NextGen Sequencing)
ATGGCCACGCTTCTCCTTCTCCTTGGGGTGCTGGTGGTAAGCCCAGACGCTCTGGGGAGC
ACAACAGCAGTGCAGACACCCACCTCCGGAGAGCCTTTGGTCTCTACTAGCGAGCCCCTG
AGCTCAAAGATGTACACCACTTCAATAACAAGTGACCCTAAGGCCGACAGCACTGGGGAC
CAGACCTCAGCCCTACCTCCCTCAACTTCCATCAATGAGGGATCCCCTCTTTGGACTTCC
ATTGGTGCCAGCACTGGTTCCCCTTTACCTGAGCCAACAACCTACCAGGAAGTTTCCATC
AAGATGTCATCAGTGCCCCAGGAAACCCCTCATGCAACCAGTCATCCTGCTGTTCCCATA
ACAGCAAACTCTCTAGGATCCCACACCGTGACAGGTGGAACCATAACAACGAACTCTCCA
GAAACCTCCAGTAGGACCAGTGGAGCCCCTGTTACCACGGCAGCTAGCTCTCTGGAGACC
TCCAGAGGCACCTCTGGACCCCCTCTTACCATGGCAACTGTCTCTCTGGAGACTTCCAAA
GGCACCTCTGGACCCCCTGTTACCATGGCAACTGACTCTCTGGAGACCTCCACTGGGACC
ACTGGACCCCCTGTTACCATGACAACTGGCTCTCTGGAGCCCTCCAGCGGGGCCAGTGGA
CCCCAGGTCTCTAGCGTAAAACTATCTACAATGATGTCTCCAACGACCTCCACCAACGCA
AGCACTGTGCCCTTCCGGAACCCAGATGAGAACTCACGAGGCATGCTGCCAGTGGCTGTG
CTTGTGGCCCTGCTGGCGGTCATAGTCCTCGTGGCTCTGCTCCTGCTGTGGCGCCGGCGG
CAGAAGCGGCGGACTGGGGCCCTCGTGCTGAGCAGAGGCGGCAAGCGTAACGGGGTGGTG
GACGCCTGGGCTGGGCCAGCCCAGGTCCCTGAGGAGGGGGCCGTGACAGTGACCGTGGGA
GGGTCCGGGGGCGACAAGGGCTCTGGGTTCCCCGATGGGGAGGGGTCTAGCCGTCGGCCC
ACGCTCACCACTTTCTTTGGCAGACGGAAGTCTCGCCAGGGCTCCCTGGCGATGGAGGAG
CTGAAGTCTGGGTCAGGCCCCAGCCTCAAAGGGGAGGAGGAGCCACTGGTGGCCAGTGAG
GATGGGGCTGTGGACGCCCCAGCTCCTGATGAGCCCGAAGGGGGAGACGGGGCTGCCCCT
TAA

Clone variation with respect to NM_003123.3
>OriGene 5' read for NM_003123 unedited
NGGTTCGGATTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGGACCTGGC
CCCAGTGCTGCGTCCTTATCAGCCGAGCCGGTCCCAGCTCTTGCTCCTGCCTGTTTGCCT
GGAAATGGCCACGCTTCTCCTTCTCCTTGGGGTGCTGGTGGTAAGCCCAGACGCTCTGGG
GAGCACAACAGCAGTGCAGACACCCACCTCCGGAGAGCCTTTGGTCTCTACTAGCGAGCC
CCTGAGCTCAAAGATGTACACCACTTCAATAACAAGTGACCCTAAGGCCGACAGCACTGG
GGACCAGACCTCAGCCCTACCTCCCTCAACTTCCATCAATGAGGGATCCCCTCTTTGGAC
TTCCATTGGTGCCAGCACTGGTTCCCCTTTACCTGAGCCAACAACCTACCAGGAAGTTTC
CATCAAGATGTCATCAGTGCCCCAGGAAACCCCTCATGCAACCAGTCATCCTGCTGTTCC
CATAACAGCAAACTCTCTAGGATCCCACACCGTGACAGGTGGAACCATAACAACGAACTC
TCCAGAAACCTCCAGTAGGACCAGTGGAGCCCCTGTTACCACGGCAGCTAGCTCTCTGGA
GACCTCCAGAGGCACCTCTGGACCCCCTCTTACCATGGCAACTGTCTCTCTGGAGACTTC
CAAAGGCACCTCTGGACCCCCTGTTACCATGGCAACTGACTCTCTGGAGACCTCCACTGG
GACCACTGGACCCNCTGTTACCATGACAACTGGCTCTCTGGAGCCCTCCAGCGGGGCCAG
TGGACCCCAGGTCTCTAGCGTAAAACTATCTACAATGATGTCTCCAACGACCTNCACCAA
CGCAAGCACTGTGCCCTTCCCGAACCCAGATGAGAACTCACGAGGCATGCTGCCAGTGGC
TGTGCTTGTGGCCCCTGCTGCNGTCATAGTCCT
>OriGene 3' read for NM_003123 unedited
CGGCCGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTGGAGAAAAAGGGGTGGATGAG
GAGGGTTTATTCATTCAGTCCACAGACGTTGAGAGGTGCCAGCCCTGCCCTGCCCAGGCG
CTAGTTGTGGGTGCTGGGTGAGGATGGCAGCAGGAAATCCAGGGCTGAGAAGCCTCATGA
GGATTCAGAGTGAAGAGGTGGGTGAGGAGGCAAGGCGCGGAGGCTCATGTCTGTAATCTC
AGCACTTTGGGAGGCTGAGGCAGGTAGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTA
GCCAACATGGTGAAACCCCATCTCTACCAAAAATACAAAAAAGCAGCTGGGCATGGTGGT
GGGTGCCTGTAATCTCAGTTACTCGGGAAGCTGAGGCAGGAGAATCGCCTGAACTTAGGA
GGCAGAGGTTGCAGTGAACTGAGATCGTGCATTGCACTCCAGCCTGGGCGACAAAGCGAA
ACTCTGTCTCAAAAGAAAAAAAAAAAGGAGATTCGGGTGAGGATCAGGGTGCCGGGTGGA
AACATGGGAGCGAGGGGGCAGTGGGATGGTGAGAGGGAAGGTGCTGGAGGCTGGCTGAGA
TTCCGGCCTCCAGCCTCACTATTCACCGACACTTAAGGGGCAGCCCCGTCTCCCCCTTCG
GGCTCATCAGGAGCTGGGGCGTCCACAGCCCCATTCTCACTGGCCACCAGTGGCTCCTCC
TCCCCTTTGAGGCTGGGGCCTGACCCAGACTTCAGCTCCNTCATCGCCAGGGAGCCCCTG
GCGAGACTTCCGTCTGCCAAAGAAAGTGGTGAGCGTTGGCCGACGGCTAGAACCCTCCCC
ATCGGGCAACCCATAGCCCTTGTCGCCCCCGGCACCTCCCCGGTCACTTGTACGGCCCCT
TCTTAGGACCTCGGGGTTGGCCCGCCCCAGTCGTTCCCCACCCGTTACGCTTGCCCCCTT
GCCCATACCAGGCCCCA
Restriction Sites NotI-NotI     
ACCN NM_003123
Insert Size 1880 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_003123.2, NP_003114.1
RefSeq Size 2288 bp
RefSeq ORF 1203 bp
Locus ID 6693
Cytogenetics 16p11.2
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)
Gene Summary 'This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]'
Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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