STAT4 (NM_003151) Human Untagged Clone

CAT#: SC118193

STAT4 (untagged)-Human signal transducer and activator of transcription 4 (STAT4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STAT4
• Synonyms: SLEB11
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_003151, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCTCAGTGGAATCAAGTCCAACAGTTAGAAATCAAGTTTTTGGAGCAGGTGGATCAATTCTATGATG
  ACAACTTTCCCATGGAAATTCGGCATCTGTTGGCCCAATGGATTGAAAATCAAGACTGGGAGGCAGCTTC
  TAACAATGAAACCATGGCAACGATTCTTCTTCAAAACTTGTTAATACAACTGGATGAACAGTTAGGTCGT
  GTTTCCAAAGAGAAAAACCTACTCTTGATACACAATCTAAAAAGAATTAGGAAGGTCCTTCAGGGAAAAT
  TTCATGGAAATCCAATGCATGTAGCTGTGGTTATTTCAAACTGTTTAAGGGAAGAGAGGAGAATATTGGC
  TGCAGCCAACATGCCTGTCCAGGGGCCTCTAGAGAAATCCTTACAAAGTTCTTCAGTTTCAGAAAGACAG
  AGGAATGTGGAGCACAAAGTGGCTGCCATTAAAAACAGTGTGCAGATGACAGAACAAGATACCAAATACT
  TAGAAGATCTGCAAGACGAATTTGACTACAGGTATAAAACAATTCAGACAATGGATCAGAGTGACAAGAA
  TAGTGCCATGGTGAATCAGGAAGTTTTGACACTGCAGGAAATGCTTAACAGCCTCGATTTCAAGAGAAAG
  GAGGCTCTCAGTAAAATGACCCAAATCATCCATGAGACAGACCTGTTAATGAACACCATGCTCATAGAAG
  AGCTGCAAGACTGGAAGCGGCGGCAGCAAATCGCCTGCATCGGGGGTCCACTCCACAATGGGCTCGACCA
  GCTTCAGAACTGCTTTACACTATTGGCAGAAAGTCTTTTCCAACTGAGAAGGCAATTGGAGAAACTAGAG
  GAGCAATCTACCAAAATGACATATGAAGGTGATCCCATTCCAATGCAAAGAACTCACATGCTAGAAAGAG
  TCACCTTCTTGATCTACAACCTTTTCAAGAACTCATTTGTGGTTGAGCGACAGCCATGTATGCCAACCCA
  CCCTCAGAGGCCGTTGGTACTTAAAACCCTAATTCAGTTCACTGTAAAACTAAGGCTACTAATAAAATTG
  CCAGAACTAAACTATCAGGTAAAGGTTAAGGCATCAATTGACAAGAATGTTTCAACTCTAAGCAACCGAA
  GATTTGTACTTTGTGGAACTAATGTCAAAGCCATGTCTATTGAAGAATCTTCCAATGGGAGTCTCTCAGT
  AGAATTTCGACATTTGCAACCAAAGGAAATGAAGTCCAGTGCTGGAGGTAAAGGAAATGAGGGCTGTCAC
  ATGGTGACTGAAGAACTTCATTCCATAACGTTTGAAACACAGATCTGCCTCTATGGCCTGACCATAGATT
  TGGAGACCAGCTCATTGCCTGTGGTGATGATTTCCAATGTCAGTCAGTTACCTAATGCTTGGGCATCCAT
  CATTTGGTACAACGTGTCAACCAACGATTCCCAGAACTTGGTTTTCTTTAATAATCCTCCACCTGCCACA
  TTGAGTCAACTACTGGAGGTGATGAGCTGGCAGTTTTCATCGTACGTTGGTCGTGGTCTTAACTCAGATC
  AACTCCATATGCTGGCAGAGAAGCTTACAGTCCAATCTAGCTACAGTGATGGTCACCTCACCTGGGCCAA
  GTTCTGCAAGGAACATTTACCTGGTAAATCATTTACCTTTTGGACATGGCTTGAAGCAATATTGGATCTA
  ATTAAGAAACACATTCTTCCCCTTTGGATTGATGGGTATGTCATGGGCTTTGTTAGCAAAGAGAAGGAAC
  GGCTGTTGCTAAAGGATAAAATGCCTGGCACCTTTTTATTAAGATTCAGTGAAAGCCATCTCGGAGGAAT
  AACTTTCACCTGGGTGGACCATTCTGAAAGTGGGGAAGTGAGATTCCACTCTGTAGAACCCTACAATAAA
  GGCCGGTTGTCTGCTCTGCCATTCGCTGACATCCTGCGAGACTACAAAGTTATTATGGCTGAAAACATTC
  CTGAAAACCCTCTGAAGTACCTATATCCTGACATTCCCAAAGACAAAGCCTTCGGTAAACACTACAGCTC
  TCAGCCTTGCGAAGTTTCAAGACCAACAGAAAGGGGTGACAAAGGTTATGTTCCTTCTGTTTTTATCCCC
  ATCTCAACAATCCGAAGTGATTCAACAGAGCCACATTCTCCATCAGACCTTCTTCCCATGTCTCCAAGTG
  TGTATGCGGTGTTGAGAGAAAACCTGAGTCCCACAACAATTGAAACTGCAATGAAGTCTCCTTATTCTGC
  TGAATGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003151 unedited
  NGGTTCGTTTTTGTATACGACTCCTATAGGGCGGCCGCGATTCGGCACGAGGGGGACACT
  CACCCTTGGAACCCAGCTGCCATATTGTGAGGAAGCTCAAGCCACAGGGAAGGCCATGTG
  TAGGTGTTTGGGCTGATGGTGCCAGCTGAGGACCTGGTCTACTGCCAGTACAACTTATAT
  CAAGCATGTGAGTTGGCGAGCTTTTGAAAGAACTCCAGCCACAGTCACTGACCACGCTGC
  CTGAGAGACCTAGAGAGAAAACCTAGCTGAGCCAAATCAGGCCCCGGAAACCATGTCTCA
  GTGGAATCAAGTCCAACAGTTAGAAATCAAGTTTTTGGAGCAGGTGGATCAATTCTATGA
  TGACAACTTTCCCATGGAAATTCGGCATCTGTTGGCCCAATGGATTGAAAATCAAGACTG
  GGAGGCAGCTTCTAACAATGAAACCATGGCAACGATTCTTCTTCAAAACTTGTTAATACA
  ACTGGATGAACAGTTAGGTCGTGTTTCCAAAGAGAAAAACCTACTCTTGATACACAATCT
  AAAAAGAATTAGGAAGGTCCTTCAGGGAAAATTTCATGGAAATCCAATGCATGTAGCTGT
  GGTTATTTCAAACTGTTTAAGGGAAGAGAGGAGAATATTGGCTGCAGCCAACATGCCTGT
  CCAGNGGCCTCTAGAGAAATCCTTACAAAGTTCTTCAGTTTCAGAAAGACAGAGGAATGT
  GGAGCACAAAGTGGCTGCCATTAAAAACAGTGTGCAGATGACAGAACAAGATACCANATA
  CTTAGNAAGATCTGCAAGACGAANTTGACTACNAGGTATANACAATTCAGACCATGGATC
  AGAGTGACAAGAATAGTGCCATGGTGATCCAAGNAAGTTTTGACACTGCAGNAAATGCTT
  AACAGCCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003151 unedited
  GGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTCTGTTAATATTGTTATTAACAC
  TGGTTTCTTAAAGTTGTCTTATCTTGCAAGTTTATCTGAAGCTTTGGTTTCAAGCATTTC
  AGTCACAACACTCCCAATTGAGGAGTGCCACGGGAGTGTGAAGAGAGCTTCAGATGTCAA
  ACATTTCCTAGAACCTGGTATTTACAAAGCTGAAGAAATAAAATGTGGTTATTGGGCAAA
  GAACAGTCTTTAAACTTTTTCATTTGCTTCCTTTCTTGGTGCGTCAGAGTTTATCCTGTC
  ATTCAGCAGAATAAGGAGACTTCATTGCAGTTTCAATTGTTGTGGGACTCAGGTTTTCTC
  TCAACACCGCATACACACTTGGAGACATGGGAAGAAGGTCTGATGGAGAATGTGGCTCTG
  TTGAATCACTTCGGATTGTTGAGATGGGGATAAAAACAGAAGGAACATAACCTTTGTCAC
  CCCTTTCTGTTGGTCTTGAAACTTCGCAAGGCTGAGAGCTGTAGTGTTTACCGAAGGCTT
  TGTCTTTGGGAATGTCAGGATATAGGTACTTCAGAGGGTTTTCAGGAATGTTTTCAGCCA
  TAATAACTTTGTAGTCTCGCAGGATGTCAGCGAATGGCAGAGCAGACAACCGGCCTTTAT
  TGTANGGTTCTACAGAGTGGAATCTCACTTCCCCACTTTCAGAATGGTCCACCCCAGTGA
  AAAGTATTCCTCCGAGATGGCTTTCACTGAATCTTATAAAAAGGTGCCAGGCATTTTATC
  CTTTAGCACAGCCGTTCCTTCTCTTTGCTAACAAAGCCCATGACATACCCATCAATCCAA
  AGGGAAGAATGTNGTTNCTAAATAGATCCAATATGCTCCAGCCTGTCCAAAGTAATGATT
  ACCAGGTAATGTTCTGCAAACTGGGCCGGTGAGTGACATACTGTACTTGATGACTGAAGC
  TTCCTGCACTTGGAGTGACTGAGTAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003151
• Insert Size: 3070 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003151.2, NP_003142.1
• RefSeq Size: 2761 bp
• RefSeq ORF: 2247 bp
• Locus ID: 6775
• Cytogenetics: 2q32.2-q32.3
• Domains: SH2, STAT
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Jak-STAT signaling pathway
• Gene Summary: 'The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]'
  Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.