SLUG (SNAI2) (NM_003068) Human Untagged Clone

CAT#: SC118205

SNAI2 (untagged)-Human snail homolog 2 (Drosophila) (SNAI2)


  "NM_003068" in other vectors (6)

Reconstitution Protocol

USD 310.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SNAI2
Synonyms SLUG; SLUGH; SLUGH1; SNAIL2; WS2D
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_003068 edited
GAATTCGGCACGAGGAGGAGCCGGGTGACTTCAGAGGCGCCGGCCCGTCCGTCTGCCGCA
CCTGAGCACGGCCCCTGCCCGAGCCTGGCCCGCCGCGATGCTGTAGGGACCGCCGTGTCC
TCCCGCCGGACCGTTATCCGCGCCGGGCGCCCGCCAGACCCGCTGGCAAGATGCCGCGCT
CCTTCCTGGTCAAGAAGCATTTCAACGCCTCCAAAAAGCCAAACTACAGCGAACTGGACA
CACATACAGTGATTATTTCCCCGTATCTCTATGAGAGTTACTCCATGCCTGTCATACCAC
AACCAGAGATCCTCAGCTCAGGAGCATACAGCCCCATCACTGTGTGGACTACCGCTGCTC
CATTCCACGCCCAGCTACCCAATGGCCTCTCTCCTCTTTCCGGATACTCCTCATCTTTGG
GGCGAGTGAGTCCCCCTCCTCCATCTGACACCTCCTCCAAGGACCACAGTGGCTCAGAAA
GCCCCATTAGTGATGAAGAGGAAAGACTACAGTCCAAGCTTTCAGACCCCCATGCCATTG
AAGCTGAAAAGTTTCAGTGCAATTTATGCAATAAGACCTATTCAACTTTTTCTGGGCTGG
CCAAACATAAGCAGCTGCACTGCGATGCCCAGTCTAGAAAATCTTTCAGCTGTAAATACT
GTGACAAGGAATATGTGAGCCTGGGCGCCCTGAAGATGCATATTCGGACCCACACATTAC
CTTGTGTTTGCAAGATCTGCGGCAAGGCGTTTTCCAGACCCTGGTTGCTTCAAGGACACA
TTAGAACTCACACGGGGGAGAAGCCTTTTTCTTGCCCTCACTGCAACAGAGCATTTGCAG
ACAGGTCAAATCTGAGGGCTCATCTGCAGACCCATTCTGATGTAAAGAAATACCAGTGCA
AAAACTGCTCCAAAACCTTCTCCAGAATGTCTCTCCTGCACAAACATGAGGAATCTGGCT
GCTGTGTAGCACACTGAGTGACGCAATCAATGTTTACTCGAACAGAATGCATTTCTTCAC
TCCGAAGCCAAATGACAAATAAAGTCCAAAGGCATTTTCTCCTGTGCTGACCAACCAAAT
AATATGTATAGACACACACACATATGCACACACACACACACACACCCACAGAGAGAGAGC
TGCAAGAGCATGGAATTCATGTGTTTAAAGATAATCCTTTCCATGTGAAGTTTAAAATTA
CTATATATTTGCTGATGGCTAGATTGAGAGAATAAAAGACAGTAACCTTTCTCTTCAAAG
ATAAAATGAAAAGCACATTGCATCTTTTCTTCCTAAAAAAATGCAAAGATTTACATTGCT
GCCAAATCATTTCAACTGAAAAGAACAGTATTGCTTTGTAATAGAGTCTGTAATAGGATT
TCCCATAGGAAGAGATCTGCCAGACGCGAACTCAGGTGCCTTAAAAAGTATTCCAAGTTT
ACTCCATTACATGTCGGTTGTCTGGTTGCCATTGTTGAACTAAAGCCTTTTTTTGATTAC
CTGTAGTGCTTTAAAGTATATTTTTAAAAGGGAGGAAAAAAATAACAAGAACAAAACACA
GGAGAATGTATTAAAAGTATTTTTGTTTTGTTTTGTTTTTGCCAATTAACAGTATGTGCC
TTGGGGGAGGAGGGAAAGATTAGCTTTGAACATTCCTGGCGCATGCTCCATTGTCTTACT
ATTTTAAAACATTTTAATAATTTTTGAAAATTAATTAAAGATGGGAATAAGTGCAAAAGA
GGATTCTTACAAATTCATTAATGTACTTAAACTATTTCAAATGCATACCACAAATGCAAT
AATACAATACCCCTTCCAAGTGCCTTTTTAAATTGTATAGTTGATGAGTCAATGTAAATT
TGTGTTTATTTTTATATGATTGAATGAGTTCTGTATGAAACTGAGATGTTGTCTATAGCT
ATGTCTATAAACAACCTGAAGACTTGTGAAATCAATGTTTCTTTTTTAAAAAACAATTTT
CAAGTTTTTTTTACAATAAACAGTTTTGATTTAAAAAAAAAAAAAAAAAACTCGAC
>OriGene 5' read for NM_003068 unedited
GTCAGAATTTGTATACGACTCATATAGGGCGGCCGCGATTCGGCACGAGGAGGAGCCGGG
TGACTTCAGAGGCGCCGGCCCGTCCGTCTGCCGCACCTGAGCACGGCCCCTGCCCGAGCC
TGGCCCGCCGCGATGCTGTAGGGACCGCCGTGTCCTCCCGCCGGACCGTTATCCGCGCCG
GGCGCCCGCCAGACCCGCTGGCAAGATGCCGCGCTCCTTCCTGGTCAAGAAGCATTTCAA
CGCCTCCAAAAAGCCAAACTACAGCGAACTGGACACACATACAGTGATTATTTCCCCGTA
TCTCTATGAGAGTTACTCCATGCCTGTCATACCACAACCAGAGATCCTCAGCTCAGGAGC
ATACAGCCCCATCACTGTGTGGACTACCGCTGCTCCATTCCACGCCCAGCTACCCAATGG
CCTCTCTCCTCTTTCCGGATACTCCTCATCTTTGGGGCGAGTGAGTCCCCCTCCTCCATC
TGACACCTCCTCCAAGGACCACAGTGGCTCAGAAAGCCCCATTAGTGATGAAGAGGAAAG
ACTACAGTCCAAGCTTTCAGACCCCCATGCCATTGAAGCTGAAAAGTTTCAGTGCAATTT
ATGCAATAAGACCTATTCAACTTTTTCTGGGCTGGCCAAACATAAGCAGCTGCACTGCGA
TGCCCAGTCTAGAAAATCTTTCAGCTGTAAATACTGTGACAAGGAATATGTGAGCCTGGG
CGCCCTGAAGATGCATATTCGGACCCACACATTACCTTGTGTTTGCAAGATCTGCGGNCA
GGCGTTTTCCAGACCCTGGTTGCTTCAAGACACATTAGAACTCACACGGNGGAGAAGCCT
TTTTCTTGCNCCTCACTGCACAGAGCATTTGCAGACAGGTCAAATCTGAGGGCTCATCTG
CAGACCCATTNCTGATGTAAGAAATACCAGTGCANAAACTGCTNCCACACCT
>OriGene 3' read for NM_003068 unedited
GCGGCACGCAATCTAGAATCGAGTTTTTTTTTTTTTTTTTTAAATCAAAACTGTTTATTG
TAAAAAAAACTTGAAAATTGTTTTTTAAAAAAAAAACATTGATTTCACAAGTCTTCAGGT
TGTTTATAGACATAGCTATAGACAACATCTCAGTTTCATACAGAACTCATTCAATCATAT
AAAAATAAACACAAATTTACATTGACTCATCAACTATACAATTTAAAAAGGCACTTGGAA
GGGGTATTGTATTATTGCATTTGTGGTATGCATTTGAAATAGTTTAAGTACATTAATGAA
TTTGTAAGAATCCTCTTTTGCACTTATTCCCATCTTTAATTAATTTTCAAAAATTATTAA
AATGTTTTAAAATAGTAAGACAATGGAGCATGCGCCAGGAATGTTCAAAGCTAATCTTTC
CCTCCTCCCCCAAGGCACATACTGTTAATTGGCAAAAACAAAACAAAACAAAAATACTTT
TAATACATTCTCCTGAGTTTTGTTCTTGTTATTTTTTTCCTCCCTTTTAAAAATATACTT
TAAAGCACTACAGGTAATCAAAAAAAGGCTTTAGTTCAACAATGGCAACCAGACAACCGA
CATGTAATGGAGTAAACTTGGAATACTTTTTAAGGCACCTGAGTTCGCGTCTGGCAGATC
TCTTCCTATGGGAAATCCTATTACAGACTCTATTACAAAGCAATACTGTTCTTTTCAGTT
GAAATGATTTGGCAGCAATGTAAATCTTTGCATTNTTTTAGGAAGAAAAAGATGCATGTG
CTTTTCATTTTATCTTTGAAGAGAAAGTTACTGTNCTTTATTCTCTCAATCTAGCCATCA
GCAAATATATAGTAATTTTAAACTTACATGGGAAGGGATATCTTAACACATGAAATTCAT
GCTCTGCAGCTCTCTTCTGGGGNNGGNGNGNGGGGGNGGGCATATGGGGGGNGNCTATCA
TATTATTGGGTGGNCANACAGGAAAA
Restriction Sites NotI-NotI     
ACCN NM_003068
Insert Size 1900 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_003068.3, NP_003059.1
RefSeq Size 2101 bp
RefSeq ORF 807 bp
Locus ID 6591
Cytogenetics 8q11.21
Domains zf-C2H2
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Adherens junction
Gene Summary 'This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.