beta Synuclein (SNCB) (NM_003085) Human Untagged Clone

CAT#: SC118218

SNCB (untagged)-Human synuclein, beta (SNCB), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SNCB
• Synonyms: beta-synuclein; synuclein, beta
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118218 sequence for NM_003085 edited (data generated by NextGen Sequencing)
  ATGGACGTGTTCATGAAGGGCCTGTCCATGGCCAAGGAGGGCGTTGTGGCAGCCGCGGAG
  AAAACCAAGCAGGGGGTCACCGAGGCGGCGGAGAAGACCAAGGAGGGCGTCCTCTACGTC
  GGAAGCAAGACCCGAGAAGGTGTGGTACAAGGTGTGGCTTCAGTGGCTGAAAAAACCAAG
  GAACAGGCCTCACATCTGGGAGGAGCTGTGTTCTCTGGGGCAGGGAACATCGCAGCAGCC
  ACAGGACTGGTGAAGAGGGAGGAATTCCCTACTGATCTGAAGCCAGAGGAAGTGGCCCAG
  GAAGCTGCTGAAGAACCACTGATTGAGCCCCTGATGGAGCCAGAAGGGGAGAGTTATGAG
  GACCCACCCCAGGAGGAATATCAGGAGTATGAGCCAGAGGCGTAG
  
  Clone variation with respect to NM_003085.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003085 unedited
  TATTTTGTAATACGACTCACTTATAGGGCGGCCGCGATTCGGCACGAGGTGCCCGCCGCA
  GCCGCCGCTCCATCCCCAGCCCCGGCCCCGCATCCAGGCCGCCAGGATGGACGTGTTCAT
  GAAGGGCCTGTCCATGGCCAAGGAGGGCGTTGTGGCAGCCGCGGAGAAAACCAAGCAGGG
  GGTCACCGAGGCGGCGGAGAAGACCAAGGAGGGCGTCCTCTACGTCGGAAGCAAGACCCG
  AGAAGGTGTGGTACAAGGTGTGGCTTCAGTGGCTGAAAAAACCAAGGAACAGGCCTCACA
  TCTGGGAGGAGCTGTGTTCTCTGGGGCAGGGAACATCGCAGCAGCCACAGGACTGGTGAA
  GAGGGAGGAATTCCCTACTGATCTGAAGCCAGAGGAAGTGGCCCAGGAAGCTGCTGAAGA
  ACCACTGATTGAGCCCCTGATGGAGCCAGAAGGGGAGAGTTATGAGGACCCACCCCAGGA
  GGAATATCAGGAGTATGAGCCAGAGGCGTAGGGGCCCAGGAGAGCCCCCACCAGCAGCAC
  AATTCTGTCCCTGTCCCTGCCCCGCCCCCCAGAGCCAGGGCTGTCCTTAGACTCCTTCTC
  CCCAATCACGAGATCTTCCTTCCGCTCTGAGGCAACCCCCTCGGAGCCTGTGTTAGTGTC
  TGTCCATCTGTCTGTCCTACCCGCCCGCGTCCAACCCCGGNGCATGGACAGGGCCAGGGT
  TGCGGTCGCGGCTGGGAGCCTCGCCCCTCCAGTGNTGCCTCCTCCCATCCAGCGTCTGCG
  CGGATGTAGCATGTTCTATGTGTTTTTAAACGAAGATCCGAGCGACGGCTTCCTCCCCGA
  TCCCCGACAGTGCTCTCCAAGCGGCCCCCCGGCAGCCACAGAGCACCCCGCCCCGACTCC
  ATTAACCTCGCATAACCTTNTTTTTTTTTACCAAAACCACGAAGCCAGCCTGTGCCATGT
  CCCCCGCCCCATCCCAGCCGTCCCGTGCCGACACCG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003085 unedited
  CTATGTACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTACAAACAGAA
  TTAGCTTTATTCATGGACTCTCGGGGGGCGGCCGGGCCCACCCGCCCGGGACACGCTCAC
  ATGGGGGGGATGGGGACTCTCCATGCCACAATCACAACACACGACGCCCGCGTTCGGACC
  GGGCCGGCTGGGATGGGGGGCGGGGGACATGGCACAGCCTGGCTCCTGGTTTTGGTTAAA
  AAAAAAAAGGTTCTCGAGGTTAATGGGAGTCGGGCGGGGTGCTCTGGGGCTGCCCGGGGG
  CCGCTTGGAGAGCCACCTGTCGGGGATCGGGGAGGAGCCGTCGCTCGGATCTTCGTTTAA
  AAACCACATAGAACATGCTACATCCGCGCAAACCCTGGATGGGAGGAGGCAACACTGGAG
  GGGCGAGGCTTCCACCCGCGACCCGAAACCCTGGCCCTGTCCATGGCCCCGGGGTTGGAC
  GCCGGCGGGTAGGACAGACAGATGGGACAGACCCTAACCCAGCCTCCGAGGGGGTTGCCC
  CAAAGCGGAAGAAAAACTCTGGAATGGGGAAACAGGACCCTAAGGCCAACCCTGGCTTCT
  GGGGGGCGGGGCAGGGCCAGGGACCAAATCGGCCCGCCTGGAGGGGGCCCCACTGGGCCC
  CCCACCCCCTGGACAATACCAAACGACAATCCCCCGGGGCGGGCTCCCCCTACTTCATAA
  CTAACGACAATCCAACAGCGCCCCATTAACCTTGAATTCTACACAACAACCCCCGACACT
  AAACACATTCGCCATTCTTCGCTCTACCTCCCCACCTTCTTCACATTTCTAACCCCCTCT
  TA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003085
• Insert Size: 1210 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003085.3, NP_003076.1
• RefSeq Size: 1310 bp
• RefSeq ORF: 405 bp
• Locus ID: 6620
• Cytogenetics: 5q35.2
• Domains: Synuclein
• Gene Summary: 'This gene encodes a member of a small family of proteins that inhibit phospholipase D2 and may function in neuronal plasticity. The encoded protein is abundant in lesions of patients with Alzheimer disease. A mutation in this gene was found in individuals with dementia with Lewy bodies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]'
  Transcript Variant: This variant (2) lacks an exon in the 5' UTR compared to variant 1. Variants 1, 2 and 7 encode the same protein (isoform 1).